alpha-Terthienyl photosensitizes damage to pBR322 DNA.

abstract：:Solar ultraviolet B (UVB) radiation has been shown to induce inflammation, DNA damage, p53 mutations and alterations in signaling pathways eventually leading to skin cancer. In this study, we investigated whether fisetin reduces inflammatory responses and modulates PI3K/AKT/NFκB cell survival signaling pathways in UVB...

journal_title：Photochemistry and photobiology

authors： Pal HC,Athar M,Elmets CA,Afaq F

更新日期：2015-01-01 00:00:00

abstract：:In this study our aim was to determine the biophysical values of constitutive skin color in Caucasians and to define the correlation between skin color and phototype assessed according to the Fitzpatrick method. Constitutive skin color was measured on the buttock, with a Minolta CR-200 colorimeter, in a population-of ...

journal_title：Photochemistry and photobiology

authors： Rubegni P,Cevenini G,Flori ML,Fimiani M,Stanghellini E,Molinu A,Barbini P,Andreassi L

更新日期：1997-02-01 00:00:00

abstract：:Channelrhodopsins act as photoreceptors for control of motility behavior in flagellates and are widely used as genetically targeted tools to optically manipulate the membrane potential of specific cell populations ("optogenetics"). The first two channelrhodopsins were obtained from the model organism Chlamydomonas rei...

journal_title：Photochemistry and photobiology

authors： Hou SY,Govorunova EG,Ntefidou M,Lane CE,Spudich EN,Sineshchekov OA,Spudich JL

更新日期：2012-01-01 00:00:00

abstract：:Pyrimidine dimers were measured in epidermal DNA of SKH:HR1 mice following exposure to solar-simulated UV radiation (SSUV, 290-400 nm) or to UVA (320-400 nm). Mice were exposed to SSUV or UVA after topical application (2 mg/cm2) of vehicle, a UVB absorber (5% 2-ethylhexyl p-methoxycinnamate [2-EHMC]), or a broad-spect...

journal_title：Photochemistry and photobiology

authors： Ley RD,Fourtanier A

更新日期：1997-06-01 00:00:00

abstract：:Ultraviolet photolesions endow DNA with distinct structural and dynamic properties. Biophysical studies of photoproduct-containing DNA have shown that these lesions affect the mutagenic properties of DNA and damage recognition by DNA repair systems. Recently obtained high-resolution cocrystal structures of damaged DNA...

journal_title：Photochemistry and photobiology

authors： Park CJ,Lee JH,Choi BS

更新日期：2007-01-01 00:00:00

abstract：:High-altitude Andean lakes (HAAL) are a treasure chest for microbiological research in South America. Their indigenous microbial communities are exposed to extremely high UV irradiation and to multiple chemical extremes (Arsenic, high salt content, alkalinity). Microbes are found both, free-living or associated into m...

journal_title：Photochemistry and photobiology

authors： Albarracín VH,Gärtner W,Farias ME

更新日期：2016-01-01 00:00:00

abstract：:In the present study, hypericin analogs with an increased hydrophilic character were synthesized. As chemical modifications alter the lipophilicity/hydrophilicity balance together with the photophysical/chemical background of the molecule the influence of these structural changes on the cellular uptake, retention and ...

journal_title：Photochemistry and photobiology

authors： Delaey EM,Obermuëller R,Zupkó I,De Vos D,Falk H,de Witte PA

更新日期：2001-08-01 00:00:00

abstract：:The fluorescent pH probe carboxy-seminaphtorhodafluor-1 (C-Snarf-1) has been used for laser microspectro-fluorometric assays of intracellular pH in 3T3 mouse fibroblasts treated with hypocrellin A. These results are compared to those previously obtained with the structurally related hydroxylated polycyclic quinone, hy...

journal_title：Photochemistry and photobiology

authors： Chaloupka R,Sureau F,Kocisova E,Petrich JW

更新日期：1998-07-01 00:00:00

abstract：:The transport mechanisms of 5-aminolevulinic acid methyl ester (5-ALA-ME) have been studied in a human adenocarcinoma cell line (WiDr) by means of 14[C]-labeled 5-ALA-ME. The transport was found to be partly Na+ dependent, while the extracellular Cl- concentration did not affect the uptake. The transport of 5-ALA-ME i...

journal_title：Photochemistry and photobiology

authors： Gederaas OA,Holroyd A,Brown SB,Vernon D,Moan J,Berg K

更新日期：2001-02-01 00:00:00

abstract：:Vitamin D production in human skin occurs only when incident UV radiation exceeds a certain threshold. From simulations of UV irradiances worldwide and throughout the year, we have studied the dependency of the extent and duration of cutaneous vitamin D production in terms of latitude, time, total ozone, clouds, aeros...

journal_title：Photochemistry and photobiology

authors： Engelsen O,Brustad M,Aksnes L,Lund E

更新日期：2005-11-01 00:00:00

abstract：:The photodegradation of the herbicide clomazone in the presence of S(2)O(8) (2-) or of humic substances of different origin was investigated. A value of (9.4 +/- 0.4) x 10(8) m(-1) s(-1) was measured for the bimolecular rate constant for the reaction of sulfate radicals with clomazone in flash-photolysis experiments. ...

journal_title：Photochemistry and photobiology

authors： David Gara PM,Bosio GN,Arce VB,Poulsen L,Ogilby PR,Giudici R,Gonzalez MC,Mártire DO

更新日期：2009-05-01 00:00:00

abstract：:The incidence of skin cancer is increasing rapidly, particularly in the Caucasian population. Epidemiological and experimental studies demonstrated that ultraviolet radiation (UVR) is the primary cause for the increasing incidence of skin cancer. It is well known that UV irradiation induces DNA damage. If the damage i...

journal_title：Photochemistry and photobiology

authors： Bush JA,Ho VC,Mitchell DL,Tron VA,Li G

更新日期：1999-09-01 00:00:00

abstract：:Using normal, untransformed, human fibroblasts, the effectiveness of aminolevulinic (ALA)-mediated photodynamic therapy (PDT) was investigated in terms of both clonogenic survival and DNA damage. The response of normal fibroblasts was then compared with Gorlin syndrome-derived fibroblasts (basal cell nevus syndrome [B...

journal_title：Photochemistry and photobiology

authors： Haylett AK,Ward TH,Moore JV

更新日期：2003-10-01 00:00:00

abstract：:The production of vitamin D3 is a pharmaceutically relevant process, producing high added-value products. Precursors are extracts from vegetal origin but bearing mainly an E geometry in the 5,6 double bond. The synthesis of vitamin D3 (5-E-α-calcidol) with the correct Z stereochemistry in the 5,6 double bond from the ...

journal_title：Photochemistry and photobiology

authors： Estruch GA,Aramendía PF

更新日期：2012-07-01 00:00:00

abstract：:We describe here the development of monoclonal antibodies to the hapten tryptophan-riboflavin, generated by irradiation of a solution of bovine serum albumin in the presence of riboflavin. The specificity of the three obtained monoclonal antibodies, named 1E6, 5H5, 5A8 all belonging to the IgG1 isotype, was assessed b...

journal_title：Photochemistry and photobiology

authors： Diaz M,Becker MI,De Ioannes AE,Silva E

更新日期：1996-06-01 00:00:00

abstract：:A set of linear and asymmetric coumarin-imidazole hybrid compounds having a N,N-diethylamine at 7-position and imidazole at 3-position on the coumarin were synthesized. Insertion of thiophene π-spacer between coumarin and imidazole moieties (5b, 5d) leads to redshifted absorption and emission compared to 5a and 5c. Al...

journal_title：Photochemistry and photobiology

authors： Bhagwat AA,Avhad KC,Patil DS,Sekar N

更新日期：2019-05-01 00:00:00

abstract：:The retinal protonated Schiff base of bacteriorhodopsin is photoreactive to reducing agents such as NaBH4. In the present work we have studied the effect of different protein hydration levels on the photoreductive reaction, as well as the consequences of preventing isomerization around the critical C13=C14 retinal dou...

journal_title：Photochemistry and photobiology

authors： Aharoni A,Ottolenghi M,Sheves M

更新日期：2002-06-01 00:00:00

abstract：:The ultraviolet (UV) component of solar radiation is the driving force of life on earth, but it can cause photoaging and skin cancer. In this study, we investigated the effects of the glucosamine-derivative 2-(N-Acetyl)-L-phenylalanylamido-2-deoxy-β-D-glucose (NAPA) on human primary fibroblasts (FBs) stimulated in vit...

journal_title：Photochemistry and photobiology

authors： Lopreiato M,Cocchiola R,Falcucci S,Leopizzi M,Cardone M,Di Maio V,Brocco U,D'Orazi V,Calvieri S,Scandurra R,De Marco F,Scotto d'Abusco A

更新日期：2020-01-01 00:00:00

abstract：:Time-resolved singlet oxygen, O(2)(a(1)Delta(g)), phosphorescence experiments have been performed in single cells upon pulsed laser irradiation of a photosensitizer incorporated into the cell. Data recorded as a function of the partial pressure of ambient oxygen to which the cell is exposed reflect apparent values for...

journal_title：Photochemistry and photobiology

authors： Hatz S,Poulsen L,Ogilby PR

更新日期：2008-09-01 00:00:00

abstract：:The synthesis of a molecule containing hypericin and luciferin moieties joined by a tether is reported. The light-induced (in vitro) antiviral activity as well as the photophysical properties of this new compound are measured and compared with those of the parent compounds, hypericin and pseudohypericin. This tethered...

journal_title：Photochemistry and photobiology

authors： Wen J,Chowdhury P,Wills NJ,Wannemuehler Y,Park J,Kesavan S,Carpenter S,Kraus GA,Petrich JW

更新日期：2002-08-01 00:00:00

abstract：:Cis-urocanic acid (UCA), formed in the epidermis by UV irradiation of trans-UCA, has been implicated as a mediator of the immunosuppression induced by UV exposure of the skin. This review covers recent work in which the wavelength dependence of cis-UCA formation, the interaction of UCA isomers with DNA, the effects of...

journal_title：Photochemistry and photobiology

authors： Norval M,Gibbs NK,Gilmour J

更新日期：1995-08-01 00:00:00

abstract：:Hypericin is a naturally occurring photosensitizer, whose presence in plants has been responsible for cutaneous phototoxicity in grazing animals. The photosensitizing properties of this agent have recently been exploited in models for anti-tumor and anti-viral activity. The cytotoxicity of hypericin and light was asse...

journal_title：Photochemistry and photobiology

authors： Yu H,Wolford ST,Kegode R,Zhao W,Osweller GD

更新日期：1996-07-01 00:00:00

abstract：:The UVA and UVB components of sunlight can produce three classes of bipyrimidine DNA photolesions [cyclobutane pyrimidine dimers (CPDs), pyrimidine (6-4) pyrimidone photoproducts (6-4PPs) and related Dewar valence isomers (DewarPPs)]. The UVA/UVB ratio of sunlight is high in winter and low in summer in the Northern He...

journal_title：Photochemistry and photobiology

authors： Nishimura K,Ikehata H,Douki T,Cadet J,Sugiura S,Mori T

更新日期：2020-12-03 00:00:00

abstract：:Albino hairless mice (Skh: HR-1) exposed chronically to sub-erythemal doses of UV radiation display physical, visible and histological alterations. Using narrow bandwidth radiation covering the UV radiation spectrum from 280-380 nm, the wavelength dependence of these alterations was determined. The wavelength dependen...

journal_title：Photochemistry and photobiology

authors： Bissett DL,Hannon DP,Orr TV

更新日期：1989-12-01 00:00:00

abstract：:Tin oxide nanoparticles about 4 nm in size were successfully synthesized using hydrothermal method. The photocatalytic activity of the particles was determined by the decolorization of malachite green (MG) and titanium yellow (TY) under UV light. 12 ppm of MG and TY were used for the solution with an initial volume of...

journal_title：Photochemistry and photobiology

authors： Esen B,Yumak T,Sınağ A,Yıldız T

更新日期：2011-03-01 00:00:00

abstract：:Syntheses for the new photosensitizers HOSiPcOSi(CH3)2(CH2)3N(CH1)1 or 3(CH3)2, Pc 34 and Pc 25, have been developed and the order of activity of these photosensitizers and the previously reported photosensitizer Pc 4, HOSiPcOSi(CH3)2(CH2)3N(CH3)2, in the dark and with broad-band red light toward Plasmodium falciparum...

journal_title：Photochemistry and photobiology

authors： Zhao XJ,Lustigman S,Li YS,Kenney ME,Ben-Hur E

更新日期：1997-08-01 00:00:00

abstract：:Photosensitizers (PS) are compounds that can generate reactive oxygen species under irradiation of appropriate light and are widely used in photodynamic therapy (PDT). Currently, topical PDT is an effective treatment for several skin diseases, including bacterial infections, fungal mycoses and psoriasis. In addition, ...

journal_title：Photochemistry and photobiology

authors： de França BM,Ghasemishahrestani Z,de Souza GFM,da Silva RN,Queiroz DD,Pierre MBR,Pereira MD,Forero JSB,Corrêa RJ

更新日期：2020-09-23 00:00:00

abstract：:Nowadays, introducing self-cleaning properties on various fabrics under daylight irradiation for automotive and upholstery application is in a central point of research. This can be achieved by application of metal-doped TiO2 nano particles on the textile fabrics. Here, alkali hydrolysis of polyester fabric has been c...

journal_title：Photochemistry and photobiology

authors： Gaminian H,Montazer M

更新日期：2015-09-01 00:00:00

abstract：:A diffusible multitherapy resistance factor (MTRF) is produced by Cloudman S91 melanoma cells in vitro. The MTRF decreases sensitivity of the target cell line, S91/amel, to gamma-irradiation, UVC (200-280 nm) and mitomycin C (MMC). In the present study, we demonstrate that MTRF also increases the survival of S91/amel ...

journal_title：Photochemistry and photobiology

authors： Hill HZ,Hill GJ,Cieszka K,Azure M,Chowdhary I,Sayre RM

更新日期：1995-05-01 00:00:00

abstract：:Using information on solar irradiance at different latitudes derived from a radiative transfer model and a detailed in vivo action spectrum for immune suppression in a murine system, we report here calculations of the "biologically effective" irradiance of sunlight for immune suppression. From 40 degrees N to 40 degre...

journal_title：Photochemistry and photobiology

authors： De Fabo EC,Noonan FP,Frederick JE

更新日期：1990-10-01 00:00:00