Hypocrellin A photosensitization involves an intracellular pH decrease in 3T3 cells.

abstract：:Demetalation kinetics of bacteriochlorophylls (BChls) c, d and e from green sulfur photosynthetic bacteria were studied under weakly acidic conditions. Demetalation rate constants of BChl e possessing a formyl group at the 7-position were significantly smaller than those of BChls c and d, which had a methyl group at t...

journal_title：Photochemistry and photobiology

authors： Hirai Y,Tamiaki H,Kashimura S,Saga Y

更新日期：2009-09-01 00:00:00

abstract：:The modifications induced by reactive oxygen species (ROS) on fluorescent proteins (FPs) may have important implications for live cell fluorescence imaging. Using quantitative gamma-radiolysis, we have studied the ROS-induced biochemical and photophysical perturbations on recombinant cyan fluorescent protein (CFP). Af...

journal_title：Photochemistry and photobiology

authors： Alvarez L,Levin CH,Merola F,Bizouarn T,Pasquier H,Baciou L,Rusconi F,Erard M

更新日期：2010-01-01 00:00:00

abstract：:In an attempt to develop an efficient chemotherapeutic agent targeted at malignant cells that express receptors to gonadotropin releasing hormone (GnRH) we coupled [D-Lys6]GnRH covalently to an emodin derivative, i.e. emodic acid (Emo) to yield [D-Lys6(Emo)]GnRH. Emodin is a naturally occurring anthraquinone which is ...

journal_title：Photochemistry and photobiology

authors： Rahimipour S,Bilkis I,Péron V,Gescheidt G,Barbosa F,Mazur Y,Koch Y,Weiner L,Fridkin M

更新日期：2001-08-01 00:00:00

abstract：:There is a need to improve the selectivity of photodynamic therapy and for better targeting of tumor cells within specific tumor compartments. Selective in vitro phototoxicity of a human bladder carcinoma cell line 647V has been achieved by targeting sulfonated aluminum phthalocyanines (AlSPc) with monoclonal antibodi...

journal_title：Photochemistry and photobiology

authors： Morgan J,Lottman H,Abbou CC,Chopin DK

更新日期：1994-11-01 00:00:00

abstract：:The synthesis of some bromine-substituted rhodamine derivatives viz., 4,5-dibromorhodamine methyl ester (dye 2) and 4,5-dibromorhodamine n-butyl ester (dye 3) are reported. These dyes were synthesized to promote a more efficient cancer cell photosensitizer for potential use in in vitro bone marrow purging in preparati...

journal_title：Photochemistry and photobiology

authors： Pal P,Zeng H,Durocher G,Girard D,Li T,Gupta AK,Giasson R,Blanchard L,Gaboury L,Balassy A,Turmel C,Laperrière A,Villeneuve L

更新日期：1996-02-01 00:00:00

abstract：:A model of UV-induced DNA damage in oceanic bacterioplankton was developed and tested against previously published and novel measurements of cyclobutane pyrimidine dimers (CPD) in surface layers of the ocean. The model describes the effects of solar irradiance, wind-forced mixing of bacterioplankton and optical proper...

journal_title：Photochemistry and photobiology

authors： Huot Y,Jeffrey WH,Davis RF,Cullen JJ

更新日期：2000-07-01 00:00:00

abstract：:Tissue inhibitors of metalloproteinases (TIMPs) are the major endogenous regulators of metalloproteinase activity in tissues. TIMPs are able to inhibit activity of all known matrix metalloproteinases (MMPs) and thus participate in controlling extracellular matrix synthesis and degradation. We showed previously elevate...

journal_title：Photochemistry and photobiology

authors： Ardan T,Němcová L,Bohuslavová B,Klezlová A,Popelka Š,Studenovská H,Hrnčiarová E,Čejková J,Motlík J

更新日期：2016-09-01 00:00:00

abstract：:Blue visible light damage to retinal pigment epithelial cells occurs through a photooxidative mechanism and the resultant damage is hypothesized to induce or exacerbate age-related macular degeneration. The purpose of the present study was to identify changes in the cell growth and the expression of hepatocyte growth ...

journal_title：Photochemistry and photobiology

authors： Chu R,Zheng X,Chen D,Hu DN

更新日期：2006-09-01 00:00:00

abstract：:Near-infrared spectroscopy has been used to quantify the composition of healthy female breast tissue in vivo. By collecting transillumination spectra in the wavelength range 680-1100 nm at 7-9 positions on the breasts of five female volunteers, an attempt was made to quantify the intra- and intersubject variability of...

journal_title：Photochemistry and photobiology

authors： Quaresima V,Matcher SJ,Ferrari M

更新日期：1998-01-01 00:00:00

abstract：:Photodynamic therapy (PDT) of solid tumors elicits a strong, acute inflammatory response characterized by a rapid and massive infiltration of activated neutrophils into the tumor. The present study investigated the impact of PDT on the systemic and local (treatment site) kinetics of neutrophil trafficking and activity...

journal_title：Photochemistry and photobiology

authors： Cecic I,Parkins CS,Korbelik M

更新日期：2001-11-01 00:00:00

abstract：:The tetraruthenated porphyrin, mu-[meso-5,10,15,20-tetra(pyridyl)porphyrin]tetrakis[bis-(bipyridine) chloride ruthenium(II)] (TRP) is a supramolecular cationic species. The aim of the present investigation was to evaluate the photodynamic properties of TRP and Zn-TRP to damage DNA with emphasis on the mechanistic aspe...

journal_title：Photochemistry and photobiology

authors： Ravanat JL,Cadet J,Araki K,Toma HE,Medeiros MH,Mascio PD

更新日期：1998-11-01 00:00:00

abstract：:Molecular beacons (MB) are becoming more common as sequence-selective detectors of nucleic acids. Although they can easily detect single-base mismatches, they have never been used to directly detect DNA or RNA damage. To measure the degree of ultraviolet (UV) light damage in oligonucleotides, we report a novel MB appr...

journal_title：Photochemistry and photobiology

authors： Yarasi S,McConachie C,Loppnow GR

更新日期：2005-03-01 00:00:00

abstract：:To improve the understanding of human skin autofluorescence emission, the spectroscopic and microscopic characteristics of skin autofluorescence were studied using a combined fluorescence and reflectance spectroanalyzer and a fiber optic microspectrophotometer. The autofluorescence spectra of in vivo human skin were m...

journal_title：Photochemistry and photobiology

authors： Zeng H,MacAulay C,McLean DI,Palcic B

更新日期：1995-06-01 00:00:00

abstract：:Well-resolved vibrational spectra of LH2 complex isolated from two photosynthetic bacteria, Rhodobacter sphaeroides and Ectothiorhodospira sp., were obtained using surface-enhanced resonance Raman scattering (SERRS) exciting into the Qx and the Qy transitions of bacteriochlorophyll a. High-quality SERRS spectra in the...

journal_title：Photochemistry and photobiology

authors： Chumanov G,Picorel R,Ortiz de Zarate I,Cotton TM,Seibert M

更新日期：2000-05-01 00:00:00

abstract：:Vitamin D production in human skin occurs only when incident UV radiation exceeds a certain threshold. From simulations of UV irradiances worldwide and throughout the year, we have studied the dependency of the extent and duration of cutaneous vitamin D production in terms of latitude, time, total ozone, clouds, aeros...

journal_title：Photochemistry and photobiology

authors： Engelsen O,Brustad M,Aksnes L,Lund E

更新日期：2005-11-01 00:00:00

abstract：:A new water-soluble porphyrin derivative, 2,4-bis(1-decyloxyethyl)-deuteroporphyrinyl-6,7-bisaspart ic acid (C10-DP), and its metal complexes (Ga, I(n), Zn, Mn, Cu, Ni and Fe) were examined for their physicochemical properties (absorption, fluorescence, triplet lifetime and partition coefficient) and photocytotoxicity...

journal_title：Photochemistry and photobiology

authors： Ando T,Irie K,Koshimizu K,Takemura T,Nishino H,Iwashima A,Takeda N,Nakajima S,Sakata I

更新日期：1993-04-01 00:00:00

abstract：:Light emitted by electronic photographic flash units is shown to damage bacteria and human skin fibroblasts deficient in repair systems, with survival curves very similar to those produced by 254 nm short UV. The lesions induced by these flashes are as photorepairable by the photolyase enzyme as those induced by 254 n...

journal_title：Photochemistry and photobiology

authors： Menezes S,Monteiro C

更新日期：1996-09-01 00:00:00

abstract：:The incidence and prevalence of inflammatory bowel disease (IBD) are increasing worldwide. Some ecological studies show increasing incidence with increasing latitude. Ambient ultraviolet radiation varies inversely with latitude, and sun exposure of the skin is a major source of vitamin D. Vitamin D deficiency is commo...

journal_title：Photochemistry and photobiology

authors： Holmes EA,Rodney Harris RM,Lucas RM

更新日期：2019-01-01 00:00:00

abstract：:Towards our overall objectives of developing potent antimicrobial materials to combat the escalating threat to human health posed by the transmission of surface-adhering pathogenic bacteria, we have investigated the photobactericidal activity of cellulose nanocrystals that have been modified with a porphyrin-derived p...

journal_title：Photochemistry and photobiology

authors： Carpenter BL,Feese E,Sadeghifar H,Argyropoulos DS,Ghiladi RA

更新日期：2012-05-01 00:00:00

abstract：:Uveal melanoma is the most frequent intraocular cancer and the second most common form of melanoma. It metastasizes in half of the patients and the prognostic is poor. Although ultraviolet (UV) radiation is a proven risk factor for skin melanoma, the role of UV light in the etiology of uveal melanoma is still contradi...

journal_title：Photochemistry and photobiology

authors： Mallet JD,Gendron SP,Drigeard Desgarnier MC,Rochette PJ

更新日期：2014-01-01 00:00:00

abstract：:Photodynamic therapy (PDT) oxygen consumption, clonogenic cell survival, fluorescence photobleaching and photoproduct formation were investigated during benzoporphyrin derivative monoacid (BPD-MA)-PDT of MAT-LyLu cells in vitro. Cells were incubated with BPD-MA concentrations of 0.1, 0.5 or 2.5 μg mL(-1) for 2 h and t...

journal_title：Photochemistry and photobiology

authors： Weston MA,Patterson MS

更新日期：2011-09-01 00:00:00

abstract：:Confocal laser microspectrofluorometric measurements on human T47D mammary tumor cells have been performed to assess the intracellular distribution of hypericin within the various cell compartments: cytoplasmic membrane, cytoplasm and nucleus. Confocal fluorescence measurements obtained from microvolumes (approximatel...

journal_title：Photochemistry and photobiology

authors： Miskovsky P,Sureau F,Chinsky L,Turpin PY

更新日期：1995-09-01 00:00:00

abstract：:The recently discovered photo-activated adenylyl cyclase (mPAC from Microcoleus chthonoplastes) is the first PAC that owes a light-, oxygen- and voltage-sensitive (LOV) domain for blue-light sensing. The photoreaction of the mPAC receptor was studied by time-resolved UV/vis and light-induced Fourier transform infrared...

journal_title：Photochemistry and photobiology

authors： Kerruth S,Langner P,Raffelberg S,Gärtner W,Heberle J

更新日期：2017-05-01 00:00:00

abstract：:Solar ultraviolet B (UVB) radiation has been shown to induce inflammation, DNA damage, p53 mutations and alterations in signaling pathways eventually leading to skin cancer. In this study, we investigated whether fisetin reduces inflammatory responses and modulates PI3K/AKT/NFκB cell survival signaling pathways in UVB...

journal_title：Photochemistry and photobiology

authors： Pal HC,Athar M,Elmets CA,Afaq F

更新日期：2015-01-01 00:00:00

abstract：:In this paper, we propose a new physical method in combination with mixed solution of thiazone and polyethylene glycol 400 (thiazone PEG 400 solution) penetration into tissue to assess the skin optical clearing. Four treatments were performed: (1) control group (C); (2) polyethylene glycol 400 (PEG400); (3) 0.25% thia...

journal_title：Photochemistry and photobiology

authors： Zhong H,Guo Z,Wei H,Guo L,Wang C,He Y,Xiong H,Liu S

更新日期：2010-05-01 00:00:00

abstract：:We examined the influence of solar ultraviolet-B radiation (UV-B; 280-320 nm) on the growth, biomass production and phenylpropanoid concentrations of Deschampsia antarctica during the springtime ozone depletion season at Palmer Station, along the Antarctic Peninsula. Treatments involved placing filters on frames over ...

journal_title：Photochemistry and photobiology

authors： Ruhland CT,Xiong FS,Clark WD,Day TA

更新日期：2005-09-01 00:00:00

abstract：:We recently reported that variations in cellular phototoxicity among a series of alkynyl-substituted zinc trisulfophthalocyanines (ZnPcS3Cn) correlates with their hydrophobicity, with the most amphiphilic derivatives showing the highest cell uptake and phototoxicity. In this study we address the role of the plasma mem...

journal_title：Photochemistry and photobiology

authors： Cauchon N,Nader M,Bkaily G,van Lier JE,Hunting D

更新日期：2006-11-01 00:00:00

abstract：:The dependence of autofluorescence properties on the metabolic and functional engagement and on the transformation condition was studied on single cells. Normal Galliera rat fibroblasts at low subculture passage (cell strain), at high subculture passage (stabilized cell line), and transformed cell line derived from a ...

journal_title：Photochemistry and photobiology

authors： Croce AC,Spano A,Locatelli D,Barni S,Sciola L,Bottiroli G

更新日期：1999-03-01 00:00:00

abstract：:Solar light leads to thymine dimers that are mutagenic and primary cause of skin cancer. Here, we report absorption and synchrotron radiation circular dichroism (CD) spectra of Tn single strands with different number n of bases (n = 2-7, 10, 11) recorded after various 254 nm irradiation times. From a principal compone...

journal_title：Photochemistry and photobiology

authors： Baggesen LM,Hoffmann SV,Nielsen SB

更新日期：2014-01-01 00:00:00

abstract：:Activation of expression of the heme oxygenase (HO) gene appears to be involved in a cellular defense system in mammalian cells. We now demonstrate that while HO-1 mRNA levels are strongly inducible in dermal fibroblasts they are barely inducible in human epidermal keratinocytes following oxidative stress (UVA radiati...

journal_title：Photochemistry and photobiology

authors： Applegate LA,Noël A,Vile G,Frenk E,Tyrrell RM

更新日期：1995-03-01 00:00:00