Terpenoids from the octocorals Menella sp. (Plexauridae) and Lobophytum crassum (Alcyonacea).

Abstract:

:A new germacrane-type sesquiterpenoid, menelloide E (1), and a new cembrane-type diterpenoid, lobocrassin F (2), were isolated from the octocorals Menella sp. and Lobophytum crassum, respectively. The structures of terpenoids 1 and 2 were determined by spectroscopic and chemical methods and compound 2 was found to display a significant inhibitory effect on the release of elastase by human neutrophils.

journal_name

Mar Drugs

journal_title

Marine drugs

authors

Lee CH,Kao CY,Kao SY,Chang CH,Su JH,Hwang TL,Kuo YH,Wen ZH,Sung PJ

doi

10.3390/md10020427

subject

Has Abstract

pub_date

2012-02-01 00:00:00

pages

427-38

issue

2

issn

1660-3397

pii

marinedrugs-10-00427

journal_volume

10

pub_type

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