Effects of Polycan, a β-glucan, on experimental periodontitis and alveolar bone loss in Sprague-Dawley rats.

abstract：:Deepened periodontal pockets exert a significant pathological burden on the host and its immune system, particularly in a patient with generalized moderate to severe periodontitis. This burden is extensive and longitudinal, occurring over decades of disease development. Considerable diagnostic and prognostic successes...

journal_title：Journal of periodontal research

authors： Elashiry M,Meghil MM,Arce RM,Cutler CW

更新日期：2019-02-01 00:00:00

abstract：:Bursts of periodontal destruction are modelled as percolation-driven phase shift events. Percolation theory, though widely used to study the flow of liquids through porous nonliving materials (e.g., soils and rocks), can be applied to bacterial or toxicological penetration of living tissue in only an approximate sense...

journal_title：Journal of periodontal research

authors： Cohen ME

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:The aim of this study was to evaluate the effect of radiotherapy on the osseointegration of dental implants in the tibia and the action of platelet-rich plasma (PRP) as an adjuvant therapy. MATERIAL AND METHODS:A total of 18 rabbits received two implants in each tibial epiphysis, totalizing 7...

journal_title：Journal of periodontal research

authors： Ocaña RP,Rabelo GD,Sassi LM,Rodrigues VP,Alves FA

更新日期：2017-06-01 00:00:00

abstract：BACKGROUND/OBJECTIVES:Endotoxin tolerance is characterized by a state of hyporesponsiveness after confrontation with endotoxins such as lipopolysaccharides (LPS) at low concentrations. The aim of this study was to investigate, whether pretreatment with Porphyromonas gingivalis leads to endotoxin tolerance induction and...

journal_title：Journal of periodontal research

authors： Blufstein A,Behm C,Nguyen PQ,Rausch-Fan X,Andrukhov O

更新日期：2018-08-01 00:00:00

abstract：:The matrix metalloproteinases (MMPs) collagenase, gelatinase A (72 kDa gelatinase), stromelysin, and their specific inhibitor TIMP-1 (tissue inhibitor of metalloproteinases), were immunolocalized using specific polyclonal antisera in gingival tissues from 21 patients with chronic inflammatory periodontal disease. Mono...

journal_title：Journal of periodontal research

authors： Meikle MC,Hembry RM,Holley J,Horton C,McFarlane CG,Reynolds JJ

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Retinoic acid (RA) exerts a wide variety of effects on development, cellular differentiation and homeostasis in various tissues. However, little is known about the effects of RA on the differentiation of periodontal ligament cells. In this study, we investigated whether RA can affect the dexam...

journal_title：Journal of periodontal research

authors： Shibuya N,Nemoto E,Kanaya S,Kunii R,Shimauchi H

更新日期：2005-12-01 00:00:00

abstract：:Recently, a relationship was demonstrated between the thickness of the cementum layer in rat molars and the activity of alkaline phosphatase (ALP) in the adjoining periodontal ligament (PDL). It was the aim of the present study to investigate whether such a relationship also exists in the periodontium of man. Healthy ...

journal_title：Journal of periodontal research

authors： van den Bos T,Beertsen W

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The purpose of this study was to determine any difference between Porphyromonas gingivalis isolates from periodontally healthy sites as compared to those from diseased sites with respect to the ability to invade host cells. MATERIAL AND METHODS:Subgingival plaque samples were obtained from per...

journal_title：Journal of periodontal research

authors： Jandik KA,Bélanger M,Low SL,Dorn BR,Yang MC,Progulske-Fox A

更新日期：2008-10-01 00:00:00

abstract：:The immunoglobulin class distribution of antibody to human collagen type I has been examined in sera and gingival extracts from patients with adult chronic periodontitis. Tissue extracts were made either by simple washing or ultrasonication. With either method, IgG and IgA antibodies to collagen were present in higher...

journal_title：Journal of periodontal research

authors： Anusaksathien O,Singh G,Matthews N,Dolby AE

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Chronic infections have been reported to be risk factors for coronary heart disease and ischemic stroke. However, the association of coronary heart disease and ischemic stroke with periodontal disease, which is also a chronic inflammatory disease, needs to be evaluated. The present case-control...

journal_title：Journal of periodontal research

authors： Pradeep AR,Hadge P,Arjun Raju P,Shetty SR,Shareef K,Guruprasad CN

更新日期：2010-04-01 00:00:00

abstract：:This study reports the immunohistochemical localization of TGF-beta receptor type II (T beta R-II) and type III (T beta R-III) in cells of the forming periodontal ligament (PDL) in rat first molar roots. Mandibular periodontium was obtained from 3, 6 and 12-wk-old rats. This represented tissue from the initial, pre-ma...

journal_title：Journal of periodontal research

authors： Gao J,Symons AL,Bartold PM

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Gingival crevicular fluid has been of major interest for many decades as a valuable body fluid that may serve as a source of biomarkers for both periodontal and systemic diseases. Owing to its very small sample size, submicroliter volumes, identification of its protein composition by classical ...

journal_title：Journal of periodontal research

authors： Carneiro LG,Venuleo C,Oppenheim FG,Salih E

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:After tooth formation is complete, it is suggested that continuity exists between the epithelial cell rests of Malassez (ERM), reduced enamel epithelium (REE) and subsequently the junctional epithelium. However, the junctional epithelium was reported to differ from REE and ERM. The developmenta...

journal_title：Journal of periodontal research

authors： Li S,Ge S,Yang P

更新日期：2015-12-01 00:00:00

abstract：OBJECTIVE:To describe the periodontal conditions among 30-39- and 50-59-year-old rural Thais from the Province of Songkhla, Southern Thailand. METHODS:A total of 359 dentate persons were given a clinical examination comprising recordings of plaque and calculus in six teeth, and bleeding on probing, attachment level an...

journal_title：Journal of periodontal research

authors： Baelum V,Pisuithanakan S,Teanpaisan R,Pithpornchaiyakul W,Pongpaisal S,Papapanou PN,Dahlén G,Fejerskov O

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Periodontal disease has been described as playing a role in the atherosclerosis process, and its relation with intimal thickness and vascular endothelial function (EF) has been investigated. The present study sought to determine whether there are differences in parameters of arterial stiffness ...

journal_title：Journal of periodontal research

authors： Nicolosi LN,Lewin PG,Rudzinski JJ,Pompeo M,Guanca F,Rodríguez P,Gelpi RJ,Rubio MC

更新日期：2017-02-01 00:00:00

abstract：AIM:This subgroup analysis of a 12-week randomized, double-blind, and two-center trial aimed to evaluate whether two different toothpaste formulations can differentially modulate the dental microbiome. MATERIAL AND METHODS:Forty one mild to moderate periodontitis patients used as an adjunct to periodontal treatment ei...

journal_title：Journal of periodontal research

authors： Hagenfeld D,Prior K,Harks I,Jockel-Schneider Y,May TW,Harmsen D,Schlagenhauf U,Ehmke B

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:High-mobility-group box 1 functions as a late-phase inflammatory mediator. It can be released extracellularly by macrophages and necrotic cells through lipopolysaccharide and tumor necrosis factor-alpha. The objective of this study was to clarify the source of high-mobility-group box 1 in chron...

journal_title：Journal of periodontal research

authors： Morimoto Y,Kawahara KI,Tancharoen S,Kikuchi K,Matsuyama T,Hashiguchi T,Izumi Y,Maruyama I

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Cannabinoid receptor CB2, expressed in osteoblasts and osteoclasts, plays a crucial role in the regulation of bone metabolism. Since periodontal ligament (PDL) cells can differentiate into osteoblasts, this study was undertaken to investigate CB2 expression and the effect of CB2 activation on o...

journal_title：Journal of periodontal research

authors： Qian H,Zhao Y,Peng Y,Han C,Li S,Huo N,Ding Y,Duan Y,Xiong L,Sang H

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The transplantation of cell sheets of mesenchymal stem cells (MSCs) is expected to be the next generation of periodontal regenerative therapy. An adequate method of multilayering MSCs has yet to be established. When cell sheets proliferate, they usually contract and detach from culture dishes a...

journal_title：Journal of periodontal research

authors： Nakamura K,Yoshimura A,Kaneko T,Sato K,Hara Y

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Fibronectin (FN) is an important cell adhesion molecule that is used widely to characterize cell behavior. Preparations of FN purified from human plasma by gelatin-Sepharose affinity chromatography typically also contain gelatin-binding gelatinases that may cleave FN, reduce its stability and a...

journal_title：Journal of periodontal research

authors： Pal S,Chen Z,Xu X,Mikhailova M,Steffensen B

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Postranslational modification of proteins can lead to the production of autoantibodies and loss of immune tolerance. This process has been hypothesised to be a critical factor in the pathogenesis of rheumatoid arthritis. The objective of this study was to demonstrate that inflamed human gingiva...

journal_title：Journal of periodontal research

authors： Bright R,Thiele GM,Manavis J,Mikuls TR,Payne JB,Bartold PM

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Alveolar bone resorption is a characteristic feature of periodontal diseases and involves the removal of both the mineral and organic constituents of the bone matrix, which is caused by either multinucleated osteoclast cells or matrix metalloproteinases (MMPs). The gram-negative bacterium, Porphyromonas ging...

journal_title：Journal of periodontal research

authors： Yun JH,Pang EK,Kim CS,Yoo YJ,Cho KS,Chai JK,Kim CK,Choi SH

更新日期：2004-10-01 00:00:00

abstract：OBJECTIVE:Smoking causes pathological changes in all tissues, including gingiva and alveolar bone. The aim of present study was to evaluate apoptotic tissue alterations and tissue destruction in smoker and non-smoker periodontitis patients and healthy individuals. METHODS:Gingival biopsy samples from 15 systemically a...

journal_title：Journal of periodontal research

authors： Karatas O,Balci Yuce H,Tulu F,Taskan MM,Gevrek F,Toker H

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Forsythia detaching factor (FDF) is a putative virulence factor of Tannerella forsythia that induces detachment of adherent cells and interleukin-8 production in human fibroblasts. The objective of the present study was to clarify the relationship between anti-FDF IgG levels in gingival crevicu...

journal_title：Journal of periodontal research

authors： Onishi H,Arakawa S,Nakajima T,Izumi Y

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The origin of cells in the mature periodontium, and the location of their progenitors, are still unknown. It is also unknown whether inflammation influences the number and distribution of these cells within the periodontium. Molecules such as STRO-1, CD146 and CD44 have been identified on a var...

journal_title：Journal of periodontal research

authors： Chen SC,Marino V,Gronthos S,Bartold PM

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:T cells and their cytokines are believed to be key factors in periodontal disease and bone resorption. We previously showed that T cells transferred to nude mice were related to inflammatory bone resorption in vivo. However, it has not been clarified whether T cells can induce bone resorption i...

journal_title：Journal of periodontal research

authors： Yamaguchi M,Ukai T,Kaneko T,Yoshinaga M,Yokoyama M,Ozaki Y,Hara Y

更新日期：2008-10-01 00:00:00

abstract：:The formation of new cementum is an important issue in clinical periodontology, as cementum is required to provide attachment for newly formed periodontal tissues to the root surface. In this study a model of cementogenesis in vitro was used in order to test the effects of root surface demineralization on the migratio...

journal_title：Journal of periodontal research

authors： Tenorio D,Foyle DM,Hughes FJ

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Cyclosporine A treatment is important in the therapy of a number of medical conditions; however, alveolar bone loss is an important negative side-effect of this drug. As such, we evaluated whether concomitant administration of simvastatin would minimize cyclosporine A-associated alveolar bone l...

journal_title：Journal of periodontal research

authors： Nassar PO,Nassar CA,Guimarães MR,Aquino SG,Andia DC,Muscara MN,Spolidorio DM,Rossa C Jr,Spolidorio LC

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:The gingiva is the first oral tissue directly exposed to cigarette smoke (CS). Exposure to CS compromises the structure and function of gingival tissue. Damaging or altering the gingival epithelium leads to a compromised protective barrier of the periodontium, resulting in several diseases. The...

journal_title：Journal of periodontal research

authors： Alharbi IA,Rouabhia M

更新日期：2016-10-01 00:00:00

abstract：:In the present study, the effect of bacterial protease on the periodontal tissues in rats was investigated histologically and histometrically. In the control group, 0.03 ml distilled water was applied to the lingual marginal gingiva of the mandibular incisor while, in the experimental group, 0.03 ml bacterial protease...

journal_title：Journal of periodontal research

authors： Suzumura Y,Kameyama Y,Mizutani M,Kato M,Kondo K,Mabuchi R

更新日期：1989-05-01 00:00:00