Time-frequency approaches for the detection of interactions and temporal properties in renal autoregulation.

abstract：:In this study, cell-material adhesive strength and cellular mechanical properties were measured using atomic force microscopy (AFM) to track cell attachment and osteogenic differentiation. First, chitosan substrates were treated with simulated body fluid (SBF) for various periods, resulting in substrates with differen...

journal_title：Annals of biomedical engineering

authors： Ho MH,Li CH,Hsiao SW,Thien DV

更新日期：2015-04-01 00:00:00

abstract：:Left ventricular (LV) diastolic filling is limited by the constraining effects exerted by the pericardium (PE) and the lung/chest wall. The aim of the present study was to assess the validity of various estimates of external cardiac constraint, compared to pericardial surface pressure (Ppe) measured lateral to the LV ...

journal_title：Annals of biomedical engineering

authors： Kingma I,Smiseth OA,Frais MA,Smith ER,Tyberg JV

更新日期：1987-01-01 00:00:00

abstract：:Radiation applied for therapy and diagnostics damages molecular/atomic couples of biotissues, bones being among them. As a result, electron peculiarities and mechanical behavior of the latter are altered. Correlation between strength of the irradiated bone and its electron features explored due to photo- and exoelectr...

journal_title：Annals of biomedical engineering

authors： Dekhtyar Y

更新日期：2001-12-01 00:00:00

abstract：:The Veterans Health Administration determined that over 250,000 U.S. service members were diagnosed with a traumatic brain injury (TBI) between 2008 and 2018, of which a great proportion were due to blast exposure. Although the penetrating (secondary) and inertia-driven (tertiary) phases of blast-induced TBI (bTBI) ha...

journal_title：Annals of biomedical engineering

authors： Vogel EW 3rd,Panzer MB,Morales FN,Varghese N,Bass CR,Meaney DF,Morrison B 3rd

更新日期：2020-04-01 00:00:00

abstract：:Femoral neck fractures are a relevant clinical and social problem. The aim of this study was to improve the prediction of patients at-risk of femoral neck fracture with respect to the current densitometric-based methods. In particular, finite element models were used to assess the prediction accuracy obtained by combi...

journal_title：Annals of biomedical engineering

authors： Testi D,Viceconti M,Cappello A,Gnudi S

更新日期：2002-06-01 00:00:00

abstract：:Defining the constituent regulatory molecules in tendon is critical to understanding the process of tendon repair and instructive to the development of novel treatment modalities. The purpose of this study is to define the structural, expressional, and mechanical changes in the tendon injury response, and elucidate th...

journal_title：Annals of biomedical engineering

authors： Dunkman AA,Buckley MR,Mienaltowski MJ,Adams SM,Thomas SJ,Satchell L,Kumar A,Pathmanathan L,Beason DP,Iozzo RV,Birk DE,Soslowsky LJ

更新日期：2014-03-01 00:00:00

abstract：:Recently, we reported that tethering and rolling of neutrophils in shear flow over a substrate of E-selectin signals activation of beta 2-integrins and firm adhesion via an intracellular signaling pathway involving phosphorylation of p38 MAP kinase. In the current study the objective was to examine the molecular mecha...

journal_title：Annals of biomedical engineering

authors： Hentzen E,McDonough D,McIntire L,Smith CW,Goldsmith HL,Simon SI

更新日期：2002-09-01 00:00:00

abstract：:Magnetic (eddy-current) stimulation of the inspiratory motor nerves in the neck of the anesthetized dog was achieved. Using a 10-turn coil wound around the base of the neck and a train of pulses (25/s), inspiration was produced by tetanic contraction of the inspiratory muscles. The volume of air inspired increased wit...

journal_title：Annals of biomedical engineering

authors： Geddes LA,Mouchawar G,Bourland JD,ElAbbady T,Nyenhuis J

更新日期：1993-05-01 00:00:00

abstract：:The long held assumption that sustained drug elution from stent coatings over weeks to months is imperative for clinical efficacy has limited the choice for stent coating materials. We developed and evaluated an omega-3 fatty acid (O3FA) based stent coating that is 85% absorbed and elutes 97% of its Sirolimus analog (...

journal_title：Annals of biomedical engineering

authors： Artzi N,Tzafriri AR,Faucher KM,Moodie G,Albergo T,Conroy S,Corbeil S,Martakos P,Virmani R,Edelman ER

更新日期：2016-02-01 00:00:00

abstract：:Intramuscular pressure (IMP) shows promise for estimating individual muscle tension in vivo. However, previous pressure measurements show high variability during isometric contraction and poor correlation with tension during dynamic contraction. We hypothesized that enhanced sensor anchoring/orientation would improve ...

journal_title：Annals of biomedical engineering

authors： O'Connor SM,Kaufman KR,Ward SR,Lieber RL

更新日期：2021-02-01 00:00:00

abstract：:A coculture of endothelial cells (ECs) and smooth muscle cells (SMCs), which mimics cellular interactions appearing in vivo, has been performed in studies on the relationship between atherogenesis and fluid shear stress conditions. Although healthy arteries in vivo consist of contractile phenotype SMCs, cultured cells...

journal_title：Annals of biomedical engineering

authors： Sakamoto N,Kiuchi T,Sato M

更新日期：2011-11-01 00:00:00

abstract：:In this work, we propose an analog electrical model of the coronary circulation for patients with obstructive disease undergoing revascularization. In this clinical situation, the collateral circulation to the occluded artery is difficult to ascertain via preoperative measurements and well-developed collaterals might ...

journal_title：Annals of biomedical engineering

authors： Maasrani M,Verhoye JP,Corbineau H,Drochon A

更新日期：2008-07-01 00:00:00

abstract：:Linear compartmental models are useful, explanatory tools, that have been widely used to represent the dynamic behavior of complex biological systems. This paper addresses the problem of the numerical identification of such models, i.e., the estimation of the parameter values that will generate predictions closest to ...

journal_title：Annals of biomedical engineering

authors： Juillet B,Bos C,Gaudichon C,Tomé D,Fouillet H

更新日期：2009-05-01 00:00:00

abstract：:Similarities between photoreceptor Kx channels and EAG and KCNQ channels suggest that the Kx channel may be related to one or both of these families of potassium channels. To provide a basis for further comparison of these channels, as well as to reveal the role of zinc (endogenously present in photoreceptors) in Kx c...

journal_title：Annals of biomedical engineering

authors： Kourennyi DE,Liu X,Barnes S

更新日期：2002-01-01 00:00:00

abstract：:We investigate the potential of prosthetic heart valves to generate abnormal flow and stress patterns, which can contribute to platelet activation and lysis according to blood damage accumulation mechanisms. High-resolution velocity measurements of the unsteady flow field, obtained with a standard particle image veloc...

journal_title：Annals of biomedical engineering

authors： Bellofiore A,Quinlan NJ

更新日期：2011-09-01 00:00:00

abstract：:A wide range of length and time scales are relevant to pharmacology, especially in drug development, drug design and drug delivery. Therefore, multiscale computational modeling and simulation methods and paradigms that advance the linkage of phenomena occurring at these multiple scales have become increasingly importa...

journal_title：Annals of biomedical engineering

authors： Clancy CE,An G,Cannon WR,Liu Y,May EE,Ortoleva P,Popel AS,Sluka JP,Su J,Vicini P,Zhou X,Eckmann DM

更新日期：2016-09-01 00:00:00

abstract：:Percutaneous stent implantation has revolutionized the clinical treatment of occluded arteries. Nevertheless, there is still a large unmet need to prevent re-occlusion after implantation. Consequently, a niche exists for a cost-effective pre-clinical method of evaluating novel interventional devices in human models. T...

journal_title：Annals of biomedical engineering

authors： Punchard MA,O'Cearbhaill ED,Mackle JN,McHugh PE,Smith TJ,Stenson-Cox C,Barron V

更新日期：2009-07-01 00:00:00

abstract：:This study presents a novel approach to modeling the electrocardiogram (ECG): the Gaussian pulse decomposition. Constituent waves of the ECG are decomposed into and represented by Gaussian pulses using an iterative algorithm: the chip away decomposition (ChAD) algorithm. At each iteration, a nonlinear minimization met...

journal_title：Annals of biomedical engineering

authors： Suppappola S,Sun Y,Chiaramida SA

更新日期：1997-03-01 00:00:00

abstract：:Accurate identification of contracting muscles can help us to understand the muscle function in both physiological and pathological conditions. Conventional electromyography (EMG) have limited access to deep muscles, crosstalk, or instability in the recordings. Accordingly, a novel framework was developed to detect co...

journal_title：Annals of biomedical engineering

authors： Zheng Y,Shin H,Kamper DG,Hu X

更新日期：2021-01-01 00:00:00

abstract：:We attempted to estimate in living adherent epithelial alveolar cells, the degree of structural and mechanical heterogeneity by considering two individualized cytoskeleton components, i.e., a submembranous "cortical" cytoskeleton and a "deep" cytoskeleton (CSK). F-actin structure characterizing each CSK component was ...

journal_title：Annals of biomedical engineering

authors： Laurent VM,Fodil R,Cañadas P,Féréol S,Louis B,Planus E,Isabey D

更新日期：2003-11-01 00:00:00

abstract：:A python computer package is developed to segment and analyze scanning electron microscope (SEM) images of scaffolds for bone tissue engineering. The method requires only a portion of an SEM image to be labeled and used for training. The algorithm is then able to detect the pore characteristics for other SEM images ac...

journal_title：Annals of biomedical engineering

authors： Rouhollahi A,Ilegbusi O,Foroosh H

更新日期：2020-10-15 00:00:00

abstract：:A recent analytical solution of the three-dimensional Stokes flow through a bumpy tube predicts that for a given bump area, there exists an optimal circumferential wavenumber which minimizes flow resistance. This study uses measurements of microvessel endothelial cell morphology to test whether this prediction holds i...

journal_title：Annals of biomedical engineering

authors： Sumagin R,Brown CW 3rd,Sarelius IH,King MR

更新日期：2008-04-01 00:00:00

abstract：:Cellular engineering applies the principles and methods of engineering to the problems of cell and molecular biology of both a basic and applied nature. As biomedical engineering has shifted from the organ and tissue level to the cellular and sub-cellular level, cellular engineering has emerged as a new area. A corner...

journal_title：Annals of biomedical engineering

authors： Nerem RM

更新日期：1991-01-01 00:00:00

abstract：:A two-dimensional sheet model was used to study the dynamics of reentry around a zone of functional block. The sheet is a set of parallel, continuous, and uniform cables, transversely interconnected by a brick-wall arrangement of fixed resistors. In accord with experimental observations on cardiac tissue, longitudinal...

journal_title：Annals of biomedical engineering

authors： Leon LJ,Roberge FA,Vinet A

更新日期：1994-11-01 00:00:00

abstract：:Dynamic occlusal loading during mastication is clinically relevant in the design and functional assessment of dental restorations and removable dentures, and in evaluating temporomandibular joint dysfunction. The aim of this study was to develop a modelling framework to evaluate subject-specific dynamic occlusal loadi...

journal_title：Annals of biomedical engineering

authors： Woodford SC,Robinson DL,Edelmann C,Mehl A,Röhrle O,Vee Sin Lee P,Ackland DC

更新日期：2021-01-06 00:00:00

abstract：:In vitro stent-induced thromboembolism was altered by the presence of residual stenoses placed upstream or placed upstream and downstream of the stent. Heparinized (3 micro/ml) bovine blood was gravity fed through a conduit with a deployed coronary stent. Embolism was continuously monitored using a light-scattering mi...

journal_title：Annals of biomedical engineering

authors： Sukavaneshvar S,Rosa GM,Solen KA

更新日期：2000-02-01 00:00:00

abstract：:Upon nerve injury, the body creates an environment consisting of permissive and non-permissive cues that instruct the function of cells involved in nerve repair. Among other roles, the developing extracellular matrix (ECM) acts as an underlying substrate to guide the union of neurites extending from the proximal stump...

journal_title：Annals of biomedical engineering

authors： Man AJ,Leach JK,Bannerman P

更新日期：2014-06-01 00:00:00

abstract：:Polycrystalline silicon (poly-Si) micromechanical structures can be made by selectively etching an underlying sacrificial oxide layer. Advantages of this micromachining technique are its simplicity and compatibility with conventional integrated-circuit processing. Compressive internal stress in poly-Si films constrain...

journal_title：Annals of biomedical engineering

authors： Howe RT

更新日期：1986-01-01 00:00:00

abstract：:New porous implant designs made possible by additive manufacturing allow for increased osseointegration, potentially improving implant performance and longevity for patients that require massive bone implants. The aim of this study was to evaluate how implantation and the strain distribution in the implant affect the ...

journal_title：Annals of biomedical engineering

authors： Cheong VS,Fromme P,Coathup MJ,Mumith A,Blunn GW

更新日期：2020-01-01 00:00:00

abstract：:We examine the low-frequency limit of hearing of the mammalian ear through the analytical modelling of the natural frequency of the tympanic membrane. The resulting equation of the natural frequency of the modelled tympanic membrane is numerically verified against previous theoretical studies, and is statistically val...

journal_title：Annals of biomedical engineering

authors： Jabaraj DJ

更新日期：2020-01-01 00:00:00