Effect of honey on nocturnal cough and sleep quality: a double-blind, randomized, placebo-controlled study.

Abstract:

OBJECTIVES:To compare the effects of a single nocturnal dose of 3 honey products (eucalyptus honey, citrus honey, or labiatae honey) to placebo (silan date extract) on nocturnal cough and difficulty sleeping associated with childhood upper respiratory tract infections (URIs). METHODS:A survey was administered to parents on 2 consecutive days, first on the day of presentation, when no medication had been given the previous evening, and the following day, when the study preparation was given before bedtime, based on a double-blind randomization plan. Participants included 300 children aged 1 to 5 years with URIs, nocturnal cough, and illness duration of ≤ 7 days from 6 general pediatric community clinics. Eligible children received a single dose of 10 g of eucalyptus honey, citrus honey, labiatae honey, or placebo administered 30 minutes before bedtime. Main outcome measures were cough frequency, cough severity, bothersome nature of cough, and child and parent sleep quality. RESULTS:In all 3 honey products and the placebo group, there was a significant improvement from the night before treatment to the night of treatment. However, the improvement was greater in the honey groups for all the MAIN OUTCOME MEASURES: CONCLUSIONS:Parents rated the honey products higher than the silan date extract for symptomatic relief of their children's nocturnal cough and sleep difficulty due to URI. Honey may be a preferable treatment for cough and sleep difficulty associated with childhood URI.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Cohen HA,Rozen J,Kristal H,Laks Y,Berkovitch M,Uziel Y,Kozer E,Pomeranz A,Efrat H

doi

10.1542/peds.2011-3075

subject

Has Abstract

pub_date

2012-09-01 00:00:00

pages

465-71

issue

3

eissn

0031-4005

issn

1098-4275

pii

peds.2011-3075

journal_volume

130

pub_type

杂志文章,多中心研究,随机对照试验
  • Thyroid-Stimulating Hormone Reference Ranges for Preterm Infants.

    abstract:BACKGROUND AND OBJECTIVES:Many newborn screening (NBS) programs now perform repeat or serial NBS to detect congenital hypothyroidism. There is wide variation in thyroid-stimulating hormone (TSH) cutoffs used by NBS programs. Data on TSH reference ranges in preterm infants at increasing postnatal age are limited. Our st...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-0290

    authors: Kaluarachchi DC,Allen DB,Eickhoff JC,Dawe SJ,Baker MW

    更新日期:2019-08-01 00:00:00

  • Addressing parental smoking in pediatrics and family practice: a national survey of parents.

    abstract:BACKGROUND:Parental smoking has been associated with increased rates of sudden infant death syndrome, low birth weight, otitis media, asthma, and decreased lung growth. No prior parent surveys have assessed national rates of screening and counseling for parental tobacco use in the context of their child's visit to prim...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.112.5.1146

    authors: Winickoff JP,McMillen RC,Carroll BC,Klein JD,Rigotti NA,Tanski SE,Weitzman M

    更新日期:2003-11-01 00:00:00

  • A Previously Healthy Adolescent With Acute Psychosis and Severe Hyperhidrosis.

    abstract::A previously healthy 15-year-old boy presented with 3 months of progressive psychosis, insomnia, back and groin pain, and hyperhidrosis. On examination, the patient was disheveled, agitated, and soaked with sweat, with systolic blood pressure in the 160s and heart rate in the 130s. Aside from occasional auditory and v...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-3786

    authors: Rosenblatt T,Ort K,Shaw R,Levy RJ,Chen C,Niemi A,Hoang K

    更新日期:2020-06-01 00:00:00

  • Alcohol Use by Youth.

    abstract::Alcohol use continues to be problematic for youth and young adults in the United States. Understanding of neurobiology and neuroplasticity continues to highlight the potential adverse impact of underage drinking on the developing brain. This policy statement provides the position of the American Academy of Pediatrics ...

    journal_title:Pediatrics

    pub_type: 杂志文章,实务指引

    doi:10.1542/peds.2019-1356

    authors: Quigley J,COMMITTEE ON SUBSTANCE USE AND PREVENTION.

    更新日期:2019-07-01 00:00:00

  • Back to sleep: can we influence child care providers?

    abstract:OBJECTIVE:Despite the fact that 20% of sudden infant death syndrome (SIDS) deaths occur in child care settings, many child care providers continue to be unaware of the association of SIDS and infant sleep position and/or are misinformed as to the risks and benefits of the various sleep positions. The objective of this ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.112.4.878

    authors: Moon RY,Oden RP

    更新日期:2003-10-01 00:00:00

  • Sudden infant death syndrome and small airway occlusion: facts and a hypothesis.

    abstract::Respiratory failure is almost certainly the cause of death in the majority of cases of sudden infant death syndrome (SIDS), but the mechanisms leading to it have not been elucidated. SIDS shares many environmental and socioeconomic risk factors with severe forms of bronchiolitis, and the age distribution of incident c...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:

    authors: Martinez FD

    更新日期:1991-02-01 00:00:00

  • Effect of antibiotic therapy and etiologic microorganism on the risk of bacterial meningitis in children with occult bacteremia.

    abstract:OBJECTIVE:To quantify the effect of antibiotic therapy on the probability of subsequent bacterial meningitis in children with fever without source treated as outpatients. DESIGN:Bayesian meta-analyses. REPORTS INCLUDED: All reports of the organism-specific prevalence of occult bacteremia in children with fever without...

    journal_title:Pediatrics

    pub_type: 杂志文章,meta分析

    doi:

    authors: Baraff LJ,Oslund S,Prather M

    更新日期:1993-07-01 00:00:00

  • Iodine deficiency, pollutant chemicals, and the thyroid: new information on an old problem.

    abstract::Many women of reproductive age in the United States are marginally iodine deficient, perhaps because the salt in processed foods is not iodized. Iodine deficiency, per se, can interfere with normal brain development in their offspring; in addition, it increases vulnerability to the effects of certain environmental pol...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2014-0900

    authors: Council on Environmental Health.,Rogan WJ,Paulson JA,Baum C,Brock-Utne AC,Brumberg HL,Campbell CC,Lanphear BP,Lowry JA,Osterhoudt KC,Sandel MT,Spanier A,Trasande L

    更新日期:2014-06-01 00:00:00

  • Iatrogenic Cushing's Syndrome Due to Intranasal Usage of Ophthalmic Dexamethasone: A Case Report.

    abstract::Iatrogenic Cushing's syndrome (ICS) is caused by exogenous corticosteroid administration with suppression of the hypothalamic-pituitary-adrenal axis. It has been commonly described with oral and topical steroid use, but scarce reports have documented intranasal steroid usage as the etiology in infancy. In this article...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2015-3845

    authors: Orton S,Censani M

    更新日期:2016-05-01 00:00:00

  • Toward an Understanding of Advance Care Planning in Children With Medical Complexity.

    abstract:BACKGROUND AND OBJECTIVES:Children with medical complexity (CMC) often have multiple life-limiting conditions with no unifying diagnosis and an unclear prognosis and are at high risk for morbidity and mortality. Advance care planning (ACP) conversations need to be uniquely tailored to this population. Our primary objec...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-2241

    authors: Orkin J,Beaune L,Moore C,Weiser N,Arje D,Rapoport A,Netten K,Adams S,Cohen E,Amin R

    更新日期:2020-03-01 00:00:00

  • Incidence, prognosis, and risk factors for fatigue and chronic fatigue syndrome in adolescents: a prospective community study.

    abstract:OBJECTIVE:The objective of this study was to describe the incidence, prevalence, risk factors, and prognosis of fatigue, chronic fatigue, and chronic fatigue syndrome in 11- to 15-year-olds. METHODS:A random general population sample (n = 842) of British adolescents and their parents were assessed at baseline and 4 to...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-2231

    authors: Rimes KA,Goodman R,Hotopf M,Wessely S,Meltzer H,Chalder T

    更新日期:2007-03-01 00:00:00

  • Marriage and the well-being of children.

    abstract::Children's well-being has become the focal consideration in legal and public policy debates regarding same-sex marriage. In this article, we critically examine and rebut the central moral argument made by opponents of same-sex marriage: that the state should not license any domestic arrangement other than "traditional...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2012-2665

    authors: Garrett JR,Lantos JD

    更新日期:2013-03-01 00:00:00

  • An evaluation of information-seeking behaviors of general pediatricians.

    abstract:OBJECTIVE:Usage of computer resources at the point of care has a positive effect on physician decision making. Pediatricians' information-seeking behaviors are not well characterized. The goal of this study was to characterize quantitatively the information-seeking behaviors of general pediatricians and specifically co...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章

    doi:10.1542/peds.113.1.64

    authors: D'Alessandro DM,Kreiter CD,Peterson MW

    更新日期:2004-01-01 00:00:00

  • Changing Trends in Asthma Prevalence Among Children.

    abstract:BACKGROUND:Childhood asthma prevalence doubled from 1980 to 1995 and then increased more slowly from 2001 to 2010. During this second period, racial disparities increased. More recent trends remain to be described. METHODS:We analyzed current asthma prevalence using 2001-2013 National Health Interview Survey data for ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2015-2354

    authors: Akinbami LJ,Simon AE,Rossen LM

    更新日期:2016-01-01 00:00:00

  • Physical activity in children attending preschools.

    abstract:OBJECTIVE:To identify correlates of objectively measured moderate and vigorous physical activity (MVPA) in children during preschool attendance. METHODS:This cross-sectional study included data from 426 apparently healthy Danish children (49.5% boys), 5 to 6 years of age enrolled in 42 randomly selected preschools. Th...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2012-3961

    authors: Olesen LG,Kristensen PL,Korsholm L,Froberg K

    更新日期:2013-11-01 00:00:00

  • Methadone-induced rigid-chest syndrome after substantial overdose.

    abstract::We report here the case of an infant who developed life-threatening rigid-chest syndrome after receiving an accidental overdose of methadone. The child responded to narcotic reversal. Pediatric physicians should be aware of this possible complication. ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2009-3243

    authors: Lynch RE,Hack RA

    更新日期:2010-07-01 00:00:00

  • Overcrowding crisis in our nation's emergency departments: is our safety net unraveling?

    abstract::Emergency departments (EDs) are a vital component in our health care safety net, available 24 hours a day, 7 days a week, for all who require care. There has been a steady increase in the volume and acuity of patient visits to EDs, now with well over 100 million Americans (30 million children) receiving emergency care...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2004-1287

    authors: American Academy of Pediatrics Committee on Pediatric Emergency Medicine.

    更新日期:2004-09-01 00:00:00

  • First-week protein and energy intakes are associated with 18-month developmental outcomes in extremely low birth weight infants.

    abstract:OBJECTIVE:We sought to evaluate the association between early protein and energy intake and neurodevelopment and growth of extremely low birth weight (<1000 g) infants. STUDY DESIGN:Daily protein and energy intakes were collected by chart review for the first 4 weeks of life on 148 extremely low birth weight survivors...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-0211

    authors: Stephens BE,Walden RV,Gargus RA,Tucker R,McKinley L,Mance M,Nye J,Vohr BR

    更新日期:2009-05-01 00:00:00

  • Aminoglycoside-based triple-antibiotic therapy versus monotherapy for children with ruptured appendicitis.

    abstract:OBJECTIVE:We conducted a retrospective cohort study to compare the use of triple therapy versus monotherapy for children and adolescents with perforated appendicitis and to determine whether there has been a transition to monotherapy within the freestanding children's hospitals that contribute to the Pediatric Health I...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.2006-2040

    authors: Goldin AB,Sawin RS,Garrison MM,Zerr DM,Christakis DA

    更新日期:2007-05-01 00:00:00

  • Quality-of-life concerns differ among patients, parents, and medical providers in children and adolescents with congenital and acquired heart disease.

    abstract:OBJECTIVES:Mortality rates in pediatric patients with heart disease have decreased dramatically in recent decades, resulting in an increasing number of survivors with morbidities that impact quality of life. The purpose of this study was to assess and compare how heart disease affects the quality of life of the pediatr...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-2572

    authors: Marino BS,Tomlinson RS,Drotar D,Claybon ES,Aguirre A,Ittenbach R,Welkom JS,Helfaer MA,Wernovsky G,Shea JA

    更新日期:2009-04-01 00:00:00

  • Implementation of a Standardized Approach to Improve the Pediatric Discharge Medication Process.

    abstract:BACKGROUND AND OBJECTIVES:The pediatric inpatient discharge medication process is complicated, and caregivers have difficulty managing instructions. Authors of few studies evaluate systematic processes for ensuring quality in these care transitions. We aimed to improve caregiver medication management and understanding ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-2711

    authors: Philips K,Zhou R,Lee DS,Marrese C,Nazif J,Browne C,Sinnett M,Tuckman S,Modi A,Rinke ML

    更新日期:2021-02-01 00:00:00

  • Mainstream end-tidal carbon dioxide monitoring in the neonatal intensive care unit.

    abstract:BACKGROUND:Continuous noninvasive monitoring of arterial carbon dioxide (CO2) in neonatal intensive care unit (NICU) patients would help clinicians avoid complications of hypocarbia and hypercarbia. End-tidal CO2 monitoring has not been used in this population to date, but recent technical advances and the introduction...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章

    doi:10.1542/peds.101.4.648

    authors: Rozycki HJ,Sysyn GD,Marshall MK,Malloy R,Wiswell TE

    更新日期:1998-04-01 00:00:00

  • Advanced Ultrasound Techniques for Pediatric Imaging.

    abstract::Ultrasound has become a useful tool in the workup of pediatric patients because of the highly convenient, cost-effective, and safe nature of the examination. With rapid advancements in anatomic and functional ultrasound techniques over the recent years, the diagnostic and interventional utility of ultrasound has risen...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2018-2609

    authors: Hwang M,Piskunowicz M,Darge K

    更新日期:2019-03-01 00:00:00

  • Milk intolerance in children with persistent sleeplessness: a prospective double-blind crossover evaluation.

    abstract::From July 1986 to July 1988, 146 children less than 5 years of age were referred by their physicians to our university sleep clinic for continual waking and crying during sleep hours. For 85 children (58.2%), the sleeplessness was attributed to inappropriate sleep habits. For 17 children (11.6%), no explanation was fo...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Kahn A,Mozin MJ,Rebuffat E,Sottiaux M,Muller MF

    更新日期:1989-10-01 00:00:00

  • A cough algorithm for chronic cough in children: a multicenter, randomized controlled study.

    abstract:OBJECTIVES:The goals of this study were to: (1) determine if management according to a standardized clinical management pathway/algorithm (compared with usual treatment) improves clinical outcomes by 6 weeks; and (2) assess the reliability and validity of a standardized clinical management pathway for chronic cough in ...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.2012-3318

    authors: Chang AB,Robertson CF,van Asperen PP,Glasgow NJ,Masters IB,Teoh L,Mellis CM,Landau LI,Marchant JM,Morris PS

    更新日期:2013-05-01 00:00:00

  • Nutritional practices in the neonatal intensive care unit: analysis of a 2006 neonatal nutrition survey.

    abstract:OBJECTIVE:The goal of this investigation was to determine how current parenteral nutrition and enteral nutrition practice intentions for preterm infants compare with published recommendations and previous feeding practices. METHODS:A survey of feeding strategies for 3 preterm infant weight groups was sent to NICU dire...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2007-3644

    authors: Hans DM,Pylipow M,Long JD,Thureen PJ,Georgieff MK

    更新日期:2009-01-01 00:00:00

  • A cross-sectional survey of levels of care and response mechanisms for evolving critical illness in hospitalized children.

    abstract:OBJECTIVES:Recognition and treatment of evolving critical illness is a fundamental element of hospital care. Hospital systems should triage patients to receive appropriate levels of care. We describe here the levels of care, the frequency of near or actual cardiopulmonary arrest (code-blue events), identification mecha...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2006-0852

    authors: VandenBerg SD,Hutchison JS,Parshuram CS,Paediatric Early Warning System Investigators.

    更新日期:2007-04-01 00:00:00

  • Prenatal Exposure to Acetaminophen and Risk of ADHD.

    abstract:OBJECTIVES:To estimate the association between maternal use of acetaminophen during pregnancy and of paternal use before pregnancy with attention-deficit/hyperactivity disorder (ADHD) in offspring while adjusting for familial risk for ADHD and indications of acetaminophen use. METHODS:Diagnoses were obtained from the ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2016-3840

    authors: Ystrom E,Gustavson K,Brandlistuen RE,Knudsen GP,Magnus P,Susser E,Davey Smith G,Stoltenberg C,Surén P,Håberg SE,Hornig M,Lipkin WI,Nordeng H,Reichborn-Kjennerud T

    更新日期:2017-11-01 00:00:00

  • Validation of the Rapid Estimate for Adolescent Literacy in Medicine Short Form (REALM-TeenS).

    abstract:BACKGROUND:This study was designed to develop and validate a brief adolescent health literacy assessment tool (Rapid Estimate of Adolescent Literacy in Medicine Short Form [REALM-TeenS]). METHODS:We combined datasets from 2 existing research studies that used the REALM-Teen (n = 665) and conducted an item response the...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2016-3286

    authors: Manganello JA,Colvin KF,Chisolm DJ,Arnold C,Hancock J,Davis T

    更新日期:2017-05-01 00:00:00

  • Hepatitis a vaccination coverage among adolescents in the United States.

    abstract:OBJECTIVE:Hepatitis A infection causes severe disease among adolescents and adults. The Advisory Committee on Immunization Practices instituted incremental recommendations for hepatitis A vaccination (HepA) at 2 years of age based on risk (1996), in selected states (1999), and universally at 1 year of age, with vaccina...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2011-2197

    authors: Dorell CG,Yankey D,Byrd KK,Murphy TV

    更新日期:2012-02-01 00:00:00