Abstract:
:Respiratory failure is almost certainly the cause of death in the majority of cases of sudden infant death syndrome (SIDS), but the mechanisms leading to it have not been elucidated. SIDS shares many environmental and socioeconomic risk factors with severe forms of bronchiolitis, and the age distribution of incident cases is similar. Present knowledge of lung and airway development during infancy, determinants of peripheral airway patency, changes in lung surface activity in infants with SIDS, and fluid film dynamics in small airways are reviewed. It is hypothesized that many cases of SIDS may be due to a final episode of progressive peripheral bronchial occlusion in infants with preceding critically diminished conductance of the smaller airways.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Martinez FDsubject
Has Abstractpub_date
1991-02-01 00:00:00pages
190-8issue
2eissn
0031-4005issn
1098-4275journal_volume
87pub_type
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