Abstract:
OBJECTIVES:This article reports on the progress made in addressing pediatric medical device needs through the establishment of the Pediatric Device Consortia Grant Program. Pediatric practitioners should be aware of both the imperative for well-studied devices for children and the existence of recently created resources to help foster the development of such products. METHODS:This article discusses some of the challenges associated with pediatric device development and describes the implementation of section 305 of the Pediatric Medical Device Safety and Improvement Act of 2007. This statute called for the creation of nonprofit consortia to facilitate the development, production, and distribution of pediatric medical devices. RESULTS:A summary of the accomplishments of the pediatric device consortia is presented. Eleven million dollars have been awarded to 5 consortia since 2009. As of July 2012, they have collectively assisted in the development of 219 pediatric device ideas. The consortia provide innovators with both mentorship and services to help advance proposed pediatric device projects, including assistance with prototyping, identification of potential funding sources, preclinical and clinical trial design, and introductions to potential manufacturers. CONCLUSIONS:Currently, 5 federally funded pediatric device consortia exist to help advance the development of potential pediatric devices. These consortia serve as a national resource for those with ideas for medical devices that may advance the health and well-being of children.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Ulrich LC,Joseph FD,Lewis DY,Koenig RLdoi
10.1542/peds.2012-1534subject
Has Abstractpub_date
2013-05-01 00:00:00pages
981-5issue
5eissn
0031-4005issn
1098-4275pii
peds.2012-1534journal_volume
131pub_type
杂志文章相关文献
PEDIATRICS文献大全abstract:BACKGROUND:It remains unclear if fatal brain injuries in young children are characterized by immediate rapid deterioration or can present after an initial period of lucidity. This issue has legal implications in child abuse, for which understanding the clinical course affects perpetrator identification. OBJECTIVE:To d...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2004-2671
更新日期:2005-07-01 00:00:00
abstract::To investigate the possible association of chronic otitis media and school learning problems, past and current middle ear status in 53 learning-disabled (LD) children was compared to that of 56 control children without learning problems. A history of recurrent otitis media was obtained in 23% of the LD children and in...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1980-08-01 00:00:00
abstract::Adenovirus infection is common in childhood and is generally associated with self-limited disease. Cidofovir, a viral DNA polymerase inhibitor, is used to treat adenovirus infection in select populations but is not often recommended for immunocompetent patients because of limited antiviral activity and nephrotoxicity....
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2019-1632
更新日期:2020-01-01 00:00:00
abstract::Kwashiorkor, with typical edema and skin rash is occasionally seen in affluent countries as a result of severe protein restriction. Treatment is with a lactose-free formula after rehydration and sometimes after a period of parenteral alimentation. Complications of therapy included: diarrhea, congestive heart failure, ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1980-12-01 00:00:00
abstract::The effect of taurine supplementation on the absorption of a fat meal was evaluated in patients with cystic fibrosis. In a cross-over design study, five patients with cystic fibrosis (12.1 +/- 2.6 years of age) and three control subjects received either placebo or taurine (30 mg/kg/d) for two 1-week periods, a month a...
journal_title:Pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1987-10-01 00:00:00
abstract:OBJECTIVE:The goal was to describe the epidemiological features of physical education (PE)-related injuries treated in US emergency departments. METHODS:A retrospective analysis was conducted with data for children and adolescents (5-18 years of age) from the National Electronic Injury Surveillance Study of the US Con...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2008-3843
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:During the past 2 decades, celiac disease (CD) has been recognized as a multisystem autoimmune disorder. A growing body of distinct neurologic conditions such as cerebellar ataxia, epilepsy, myoclonic ataxia, chronic neuropathies, and dementia have been reported, mainly in middle-aged adults. There still are ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.113.6.1672
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVES:The goals of this study were to: (1) determine if management according to a standardized clinical management pathway/algorithm (compared with usual treatment) improves clinical outcomes by 6 weeks; and (2) assess the reliability and validity of a standardized clinical management pathway for chronic cough in ...
journal_title:Pediatrics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1542/peds.2012-3318
更新日期:2013-05-01 00:00:00
abstract::Two matched groups of children with a family history of atopy/allergy were observed from birth. In one group (n = 65) the mothers had a diet free from eggs, cow's milk, and fish during the first 3 months of lactation, whereas the mothers in the other group (n = 50) had a normal diet. Atopic/allergic manifestations, sk...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-04-01 00:00:00
abstract::Urinary concentrations of beta 2-microglobulin (beta 2M) and creatinine were measured in normal term infants and in those born with meconium-stained amniotic fluid. None of the infants or their mothers had conditions known to modify beta 2M excretion. Measurements of beta 2M were made on urines collected by bagging; u...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1985-12-01 00:00:00
abstract:OBJECTIVE:Advances in medical care have led to a growing population of special needs children who are at risk for suboptimal care when they present to a physician with no previous knowledge of their medical history. This risk may be amplified in the emergency department setting when time-sensitive interventions must be...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.102.2.367
更新日期:1998-08-01 00:00:00
abstract:CONTEXT:Language barriers affect health care interactions. Large, randomized studies of the relative efficacy of interpreter modalities have not been conducted. OBJECTIVE:To compare the efficacy of telephonic and in-person medical interpretation to visits with verified bilingual physicians. METHODS:This was a prospec...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2009-0769
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVE:Respiratory tract infections are a leading cause of morbidity and mortality worldwide. Recently, a newly identified human respiratory virus, human metapneumovirus (hMPV), was reported by investigators in the Netherlands. We sought to determine whether hMPV was circulating in our community and to determine the...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.111.6.1407
更新日期:2003-06-01 00:00:00
abstract:OBJECTIVE:To determine whether pediatric health care providers recognize maternal depressive symptoms and to explore whether maternal, provider, and visit characteristics affect pediatric providers' ability to recognize inner-city mothers with depressive symptoms. DESIGN:A cross-sectional study was conducted at a hosp...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.106.6.1367
更新日期:2000-12-01 00:00:00
abstract:OBJECTIVE:To quantify the effect of antibiotic therapy on the probability of subsequent bacterial meningitis in children with fever without source treated as outpatients. DESIGN:Bayesian meta-analyses. REPORTS INCLUDED: All reports of the organism-specific prevalence of occult bacteremia in children with fever without...
journal_title:Pediatrics
pub_type: 杂志文章,meta分析
doi:
更新日期:1993-07-01 00:00:00
abstract::Phenotypic and biological characterization of rare monogenic disorders represents 1 of the most important avenues toward understanding the mechanisms of human disease. Among patients with SH3 and multiple ankyrin repeat domains 3 (SHANK3) mutations, a subset will manifest neurologic regression, psychosis, and mood dis...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2019-1490
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:The goal was to determine whether the increasing prevalence of autism, on the basis of educational data, in Wisconsin between 2002 and 2008 was uniform in all school districts or was greatest in districts with lower baseline (2002) prevalence. METHODS:Special education counts were obtained for all Wisconsin ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2010-1023
更新日期:2010-11-01 00:00:00
abstract::Children's well-being has become the focal consideration in legal and public policy debates regarding same-sex marriage. In this article, we critically examine and rebut the central moral argument made by opponents of same-sex marriage: that the state should not license any domestic arrangement other than "traditional...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2012-2665
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:Young children are generally considered immunologically naive with respect to influenza exposure opportunities; thus, a 2-dose schedule is recommended when a child is first immunized with conventional influenza vaccine lacking adjuvant. We estimated the effectiveness of a single pediatric dose of AS03-adjuvan...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2010-3492
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVE:We sought to determine the correlates of intent to breastfeed and of successful lactation and nursing at the breast in mothers of very low birth weight (VLBW; <1.5 kg) infants. METHODS:We conducted a prospective observational study of 119 mothers of singleton VLBW infants (mean birth weight: 1056 g; mean ges...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.109.4.e57
更新日期:2002-04-01 00:00:00
abstract::In Norway, a national consensus-based guideline used to address thresholds for offering life support at extreme preterm birth was issued in 1998. Since then, therapeutic advances may have changed attitudes and expectations to treatment, both within the medical community and the public, and there are concerns that syst...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:10.1542/peds.2018-0478E
更新日期:2018-09-01 00:00:00
abstract::This article reviews the literature on possible growth-suppressing effects of stimulant medications in the long-term treatment of children with the hyperkinetic behavior syndrome. The evidence clearly indicates a temporary retardation in the rate of growth in weight and suggests a temporary slowing of growth in statur...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1979-06-01 00:00:00
abstract::Child sexual abuse criminal court cases from a 12-month period were reviewed to determine the frequency and significance of physical evidence in legally "proven" felony cases with penetration. One hundred fifteen consecutive cases were reviewed, and 87 (76%) had resulted in conviction of the perpetrator on felony char...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-09-01 00:00:00
abstract:OBJECTIVE:To examine trends in multiple births conceived using assisted reproductive technology (ART) in the United States between 1997 and 2000 and to estimate the proportion of all US multiple births attributable to ART use. METHODS:We analyzed population-based data of 109 519 live-born infants who were conceived in...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:2003-05-01 00:00:00
abstract::An overview is presented of the major methods of contraception available to the sexually active adolescent. Emphasis is given to the combined birth control pill, while the literature describing absolute and relative contraindications to oral contraception is reviewed. It is noted that adolescents with chronic illness ...
journal_title:Pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:1980-01-01 00:00:00
abstract::An organization of clinical faculty has been formed at Rainbow Babies and Childrens Hospital, Cleveland, Ohio, to help coordinate the mutual goals but sometimes conflicting needs of practicing pediatricians and a teaching hospital. The organization has been active in developing and conducting educational experiences f...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1975-08-01 00:00:00
abstract:OBJECTIVE:The goal was to evaluate the impact of cerebrospinal fluid enterovirus polymerase chain reaction testing on the length of hospitalization and the duration of antibiotic use for infants < or = 90 days of age with suspected aseptic meningitis. METHODS:This retrospective cohort study was conducted at an urban, ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2007-0252
更新日期:2007-09-01 00:00:00
abstract::Severe hypercalcemia with decreased renal function, hypertension, and renal calcifications developed in a 14-year-old boy who required prolonged immobilization for multiple fractures. Parathyroid hormone was not detectable in the serum. Urinary calcium excretion was high. Initially, mobilization was impossible and the...
journal_title:Pediatrics
pub_type: 杂志文章
doi:
更新日期:1979-01-01 00:00:00
abstract:OBJECTIVE:Propranolol hydrochloride is a safe and effective medication for treating infantile hemangiomas (IHs), with decreases in IH volume, color, and elevation. METHODS:Forty children between the ages of 9 weeks and 5 years with facial IHs or IHs in sites with the potential for disfigurement were randomly assigned ...
journal_title:Pediatrics
pub_type: 杂志文章,随机对照试验
doi:10.1542/peds.2010-0029
更新日期:2011-08-01 00:00:00
abstract::Measles is readily spread to susceptible individuals, but is no longer endemic in the United States. In March 2011, measles was confirmed in a Minnesota child without travel abroad. This was the first identified case-patient of an outbreak. An investigation was initiated to determine the source, prevent transmission, ...
journal_title:Pediatrics
pub_type: 杂志文章
doi:10.1542/peds.2013-4260
更新日期:2014-07-01 00:00:00