Thyroid-Stimulating Hormone Reference Ranges for Preterm Infants.

Abstract:

BACKGROUND AND OBJECTIVES:Many newborn screening (NBS) programs now perform repeat or serial NBS to detect congenital hypothyroidism. There is wide variation in thyroid-stimulating hormone (TSH) cutoffs used by NBS programs. Data on TSH reference ranges in preterm infants at increasing postnatal age are limited. Our study objective was to determine TSH reference ranges for preterm infants born at <32 weeks' gestation. METHODS:We analyzed serial TSH levels on NBS performed on infants born between 22 and 31 weeks' gestation from 2012 to 2016 in Wisconsin. The study cohort was divided into 2 groups (22-27 and 28-31 weeks), and TSH percentiles were defined from birth to the term equivalent gestational age. RESULTS:The study cohort consisted of 1022 and 2115 infants born at 22 to 27 and 28 to 31 weeks' gestation, respectively. The 95th percentile TSH level for the group born at 22 to 27 weeks' gestation gradually decreased and reached a nadir at ∼10 to 11 weeks. In contrast, for the group born at 28 to 31 weeks' gestation, the 95th percentile TSH level reached a nadir at ∼5 to 6 weeks. At 3 to 4 weeks after birth, the 95th percentile TSH level ranged from 11 to 11.8 μIU/mL for the group born at 22 to 27 weeks' gestation and ranged from 8.2 to 9 μIU/mL for the group born at 28 to 31 weeks' gestation. CONCLUSIONS:Using a statewide cohort of preterm infants, we constructed TSH reference charts from birth to the term equivalent gestation for preterm infants born at <32 weeks' gestation. Use of a single cutoff for all preterm infants might lead to misdiagnosis. The differences in TSH levels according to gestational-age categories might explain the increased frequency in congenital hypothyroidism diagnoses among preterm infants. These data are useful for defining age-adjusted NBS TSH cutoffs for preterm infants.

journal_name

Pediatrics

journal_title

Pediatrics

authors

Kaluarachchi DC,Allen DB,Eickhoff JC,Dawe SJ,Baker MW

doi

10.1542/peds.2019-0290

subject

Has Abstract

pub_date

2019-08-01 00:00:00

issue

2

eissn

0031-4005

issn

1098-4275

pii

peds.2019-0290

journal_volume

144

pub_type

杂志文章
  • Four patterns of response to inhaled nitric oxide for persistent pulmonary hypertension of the newborn.

    abstract:OBJECTIVE:To determine the clinical role of inhaled nitric oxide (iNO) in the treatment of persistent pulmonary hypertension of the newborn (PPHN). STUDY DESIGN:Prospective open observational clinical study. SETTING:A regional cardiac and pediatric intensive care unit. METHODS:Twenty-five consecutive near-term neona...

    journal_title:Pediatrics

    pub_type: 临床试验,杂志文章

    doi:

    authors: Goldman AP,Tasker RC,Haworth SG,Sigston PE,Macrae DJ

    更新日期:1996-10-01 00:00:00

  • Randomized, controlled trial on tracheal colonization of ventilated infants: can gravity prevent ventilator-associated pneumonia?

    abstract:OBJECTIVE:The goal was to test the hypothesis that intubated infants positioned on their sides would be less likely to contract bacterial colonization in their tracheae, compared with those positioned supine. METHODS:We conducted a prospective, randomized, controlled trial with 60 intubated infants; 30 infants were po...

    journal_title:Pediatrics

    pub_type: 杂志文章,随机对照试验

    doi:10.1542/peds.2007-1826

    authors: Aly H,Badawy M,El-Kholy A,Nabil R,Mohamed A

    更新日期:2008-10-01 00:00:00

  • The changing role and responsibilities of chairmen in clinical academic departments: the transition from autocracy.

    abstract::There is considerable literature dealing with the responsibilities of clinical department chairmen, which primarily emphasizes the importance of developing a sound and facilitating administration. This is dependent on the hiring of appropriate support personnel, developing a representative committee structure, being a...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Brent RL

    更新日期:1992-07-01 00:00:00

  • Comparison of outcome measures for a traditional pediatric faculty service and nonfaculty hospitalist services in a community teaching hospital.

    abstract:OBJECTIVE:Several studies have found decreased cost and length of stay for patients who are cared for by pediatric hospitalists compared with traditional faculty models. The objective of this study was to compare cost and length of stay between a faculty group and 2 separate hospitalist groups in a community teaching h...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2005-3146

    authors: Boyd J 3rd,Samaddar K,Parra-Roide L,Allen EP,White B

    更新日期:2006-10-01 00:00:00

  • Providing Care for Children in Immigrant Families.

    abstract::Children in immigrant families (CIF), who represent 1 in 4 children in the United States, represent a growing and ever more diverse US demographic that pediatric medical providers nationwide will increasingly encounter in clinical care. Immigrant children are those born outside the United States to non-US citizen pare...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-2077

    authors: Linton JM,Green A,COUNCIL ON COMMUNITY PEDIATRICS.

    更新日期:2019-09-01 00:00:00

  • Maternal cigarette smoking and fetal oxygen transport: a study of P50, 2,3-diphosphoglycerate, total hemoglobin, hematocrit, and type F hemoglobin in fetal blood.

    abstract::The current study was undertaken to determine whether the O2 carrying capacity of newborns born to mothers who smoke can accommodate to carbon monoxide poisoning to compensate for the potential tissue hypoxia induced by CO. From a cohort of 1,222 women and newborn infants the total hemogloblin concentration, hematocri...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Bureau MA,Shapcott D,Berthiaume Y,Monette J,Blouin D,Blanchard P,Begin R

    更新日期:1983-07-01 00:00:00

  • Biphasic anaphylactic reactions in pediatrics.

    abstract:OBJECTIVES:The objectives of this study were to: 1) determine the incidence of biphasic reactions in children with anaphylaxis; 2) establish what risk factors can predict progression to a biphasic reaction; and 3) assess the utility of inpatient observation for patients whose anaphylaxis appears to have resolved. METH...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.106.4.762

    authors: Lee JM,Greenes DS

    更新日期:2000-10-01 00:00:00

  • Amniotic fluid microviscosity determined by fluorescence polarization: methodology and relation to gestational age.

    abstract::The fluorescence polarization of 116 amniotic fluid specimens obtained from 22 isoimmunized pregnant women was determined. The degree of fluorescence polarization of amniotic fluid provides an index of microvisocity in lipid aggregates that is dependent on the lecithin-to-sphingomyelin ratio and the degree of saturati...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Stark RI,Blumenfeld TA,George JD,Freda VJ,James LS

    更新日期:1979-02-01 00:00:00

  • Immersion in water during labor and delivery.

    abstract::Immersion in water has been suggested as a beneficial alternative for labor, delivery, or both and over the past decades has gained popularity in many parts of the world. Immersion in water during the first stage of labor may be associated with decreased pain or use of anesthesia and decreased duration of labor. Howev...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2013-3794

    authors: American Academy of Pediatrics Committee on Fetus and Newborn.,American College of Obstetricians and Gynecologists Committee on Obstetric Practice.

    更新日期:2014-04-01 00:00:00

  • Intravenous ceftriaxone and calcium in the neonate: assessing the risk for cardiopulmonary adverse events.

    abstract:OBJECTIVES:Unsolicited reports regarding potentially serious adverse drug reactions in neonates and young infants were reported to the Food and Drug Administration, leading to changes in the package label for ceftriaxone. This report describes and summarizes the reported cases that led to safety concerns regarding the ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-3080

    authors: Bradley JS,Wassel RT,Lee L,Nambiar S

    更新日期:2009-04-01 00:00:00

  • Daptomycin for Complicated Skin Infections: A Randomized Trial.

    abstract:BACKGROUND:Complicated skin and skin structure infections (cSSSI) are common in children. Due to safety and resistance issues with recommended agents, new treatment options would be advantageous. METHODS:Multicenter, evaluator-blinded clinical trial. Patients 1 to 17 years old with cSSSI caused by Gram-positive pathog...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1542/peds.2016-2477

    authors: Bradley J,Glasser C,Patino H,Arnold SR,Arrieta A,Congeni B,Daum RS,Kojaoghlanian T,Yoon M,Anastasiou D,Wolf DJ,Bokesch P

    更新日期:2017-03-01 00:00:00

  • Comparison of findings on cranial ultrasound and magnetic resonance imaging in preterm infants.

    abstract:OBJECTIVE:To compare findings on hard copies of cranial ultrasound (US) and magnetic resonance imaging (MRI) obtained between birth and term in a group of preterm infants. PARTICIPANTS AND METHODS:Infants born at or below a gestational age of 30 weeks who underwent cranial US scan and MRI on the same day were eligible...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.107.4.719

    authors: Maalouf EF,Duggan PJ,Counsell SJ,Rutherford MA,Cowan F,Azzopardi D,Edwards AD

    更新日期:2001-04-01 00:00:00

  • Ensuring Timely Connection to Early Intervention for Young Children With Developmental Delays.

    abstract:BACKGROUND AND OBJECTIVES:Timely provision of developmental services can improve outcomes for children 0 to 3 years old with developmental delays. Early Intervention (EI) provides free developmental services to children under age 3 years; however, data suggests that many children referred to EI never connect to the pro...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2017-4017

    authors: Conroy K,Rea C,Kovacikova GI,Sprecher E,Reisinger E,Durant H,Starmer A,Cox J,Toomey SL

    更新日期:2018-07-01 00:00:00

  • The International Liaison Committee on Resuscitation (ILCOR) consensus on science with treatment recommendations for pediatric and neonatal patients: pediatric basic and advanced life support.

    abstract::This publication contains the pediatric and neonatal sections of the 2005 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations (COSTR). The consensus process that produced this document was sponsored by the International Liaison Committee on ...

    journal_title:Pediatrics

    pub_type: 杂志文章,实务指引

    doi:10.1542/peds.2006-0206

    authors: International Liaison Committee on Resuscitation.

    更新日期:2006-05-01 00:00:00

  • Maternal Intellectual or Developmental Disability and Newborn Discharge to Protective Services.

    abstract:BACKGROUND:Approximately half of women with intellectual and developmental disabilities (IDDs) lose custody of their children at some point in their child's development, but their rates of and risk factors for newborn discharge to child protective services from the birth hospitalization are relatively unknown. METHODS...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2018-1416

    authors: Brown HK,Potvin LA,Lunsky Y,Vigod SN

    更新日期:2018-12-01 00:00:00

  • Preschool vision screening frequency after an office-based training session for primary care staff.

    abstract:OBJECTIVE:Although vision screening for preschool children is recommended for detecting amblyopia, many pediatric and family medicine practices do not screen preschool-aged children. The aim of this study was to determine the effect of a training program for primary care clinical staff on vision screening behavior and ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.112.1.e17

    authors: Hered RW,Rothstein M

    更新日期:2003-07-01 00:00:00

  • Erythromelalgia.

    abstract::Erythromelalgia is an extraordinary disease which remains elusive in its pathophysiology and management. Victims suffer intense burning and redness of the hands and feet. In what appears to be the antithesis of Raynaud's disease, the pain is relieved by emersion in cold. A child with erythromelalgia is described whose...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Mandell F,Folkman J,Matsumoto S

    更新日期:1977-01-01 00:00:00

  • Neural tube defects: knowledge and preconceptional prevention practices in minority young women.

    abstract:OBJECTIVE:To assess 1) knowledge of neural tube defect (NTD) prevention by folic acid, 2) frequency of intake of multivitamins and folate- and folic acid-fortified food, and 3) factors associated with knowledge and prevention practices among sexually active minority adolescent and young adult women. METHODS:Young mino...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.112.3.536

    authors: Chacko MR,Anding R,Kozinetz CA,Grover JL,Smith PB

    更新日期:2003-09-01 00:00:00

  • Screening tests for urinary tract infection in children: A meta-analysis.

    abstract:OBJECTIVE:To review systematically and to summarize the existing literature regarding performance of rapid diagnostic tests for urinary tract infection (UTI) in children. DESIGN:Systematic review and meta-analysis. METHODS:Published articles reporting the performance of urine dipstick tests (leukocyte esterase [LE] a...

    journal_title:Pediatrics

    pub_type: 杂志文章,meta分析

    doi:10.1542/peds.104.5.e54

    authors: Gorelick MH,Shaw KN

    更新日期:1999-11-01 00:00:00

  • Life events and childhood morbidity: a prospective study.

    abstract::The relationship between family life events and rates of childhood morbidity was studied prospectively in a birth cohort of New Zealand children during the period from ages 1 to 4 years. Family life events were associated with increased risk of medical consultation and hospital attendance for illness of the lower resp...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:

    authors: Beautrais AL,Fergusson DM,Shannon FT

    更新日期:1982-12-01 00:00:00

  • Prolonged QTc interval in association with medium-chain acyl-coenzyme A dehydrogenase deficiency.

    abstract::Medium-chain acyl-coenzyme A dehydrogenase (MCAD) deficiency is the most common disorder of mitochondrial fatty acid oxidation. We report a term male infant who presented at 3 days of age with hypoglycemia, compensated metabolic acidosis, hypocalcemia, and prolonged QTc interval. Pregnancy was complicated by maternal ...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2013-1105

    authors: Wiles JR,Leslie N,Knilans TK,Akinbi H

    更新日期:2014-06-01 00:00:00

  • Maternal smoking and congenital heart defects.

    abstract:OBJECTIVES:In a population-based case-control study, we investigated the association between congenital heart defects and maternal smoking. METHODS:The National Birth Defects Prevention Study enrolled 3067 infants with nonsyndromic congenital heart defects and their parents and 3947 infants without birth defects and t...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2007-1519

    authors: Malik S,Cleves MA,Honein MA,Romitti PA,Botto LD,Yang S,Hobbs CA,National Birth Defects Prevention Study.

    更新日期:2008-04-01 00:00:00

  • Maternal perception of weight status and health risks associated with obesity in children.

    abstract:OBJECTIVE:To examine factors associated with the maternal perception of the weight status in related and unrelated children and to examine whether associated health risks for children's physical and mental health are recognized. PATIENTS AND METHODS:Two hundred nineteen mothers with children between 3 and 6 years of a...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2008-1845

    authors: Warschburger P,Kröller K

    更新日期:2009-07-01 00:00:00

  • Health supervision for children with fragile X syndrome.

    abstract::Fragile X syndrome (an FMR1-related disorder) is the most commonly inherited form of mental retardation. Early physical recognition is difficult, so boys with developmental delay should be strongly considered for molecular testing. The characteristic adult phenotype usually does not develop until the second decade of ...

    journal_title:Pediatrics

    pub_type: 杂志文章,评审

    doi:10.1542/peds.2010-3500

    authors: Hersh JH,Saul RA,Committee on Genetics.

    更新日期:2011-05-01 00:00:00

  • Quality Improvement Incorporating a Feedback Loop for Accurate Medication Reconciliation.

    abstract:OBJECTIVES:Medication reconciliation errors on hospital admission can lead to significant patient harm. A pediatric intermediate care unit initiated a quality improvement project and aimed to reduce errors in admission medication reconciliation by 50% in 12 months. METHODS:From August 2017 to December 2018, a multidis...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2019-2464

    authors: Russ CM,Stone S,Treseler J,Vincuilla J,Partin L,Jones E,Chu E,Currier D,Kelly DP

    更新日期:2020-12-01 00:00:00

  • Developmental Outcomes in Duarte Galactosemia.

    abstract::: media-1vid110.1542/5849572227001PEDS-VA_2018-2516Video Abstract OBJECTIVES: For decades, infants with Duarte galactosemia (DG) have been identified by newborn screening (NBS), but whether they should be treated with dietary restrictions of galactose has remained unknown. To clarify, we conducted a study of dietary a...

    journal_title:Pediatrics

    pub_type: 杂志文章,多中心研究

    doi:10.1542/peds.2018-2516

    authors: Carlock G,Fischer ST,Lynch ME,Potter NL,Coles CD,Epstein MP,Mulle JG,Kable JA,Barrett CE,Edwards SM,Wilson E,Fridovich-Keil JL

    更新日期:2019-01-01 00:00:00

  • A population-based, multisite cohort study of the predictors of chronic idiopathic thrombocytopenic purpura in children.

    abstract:OBJECTIVE:The objective of this study was to identify risk factors for developing chronic idiopathic thrombocytopenic purpura in a cohort of pediatric patients with idiopathic thrombocytopenic purpura. METHODS:We conducted a retrospective cohort analysis of 259 children who were diagnosed with idiopathic thrombocytope...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2007-1129

    authors: Glanz J,France E,Xu S,Hayes T,Hambidge S

    更新日期:2008-03-01 00:00:00

  • Poverty and chronic illness in early childhood: a comparison between the United kingdom and Quebec.

    abstract:OBJECTIVES:Our goal was to examine the association between poverty, in the first and fourth years of life and cumulatively in the first and fourth years of life, and the health of children in the fourth year of life in the UK Millennium Cohort Study and in the Quebec Longitudinal Study of Child Development (QLSCD). ME...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2009-0701

    authors: Nikiéma B,Spencer N,Séguin L

    更新日期:2010-03-01 00:00:00

  • American Academy of Pediatrics. Committee on Infecious Diseases. Prevention of Lyme disease.

    abstract::Lyme disease is currently the most frequently reported vector-borne illness in the United States, accounting for more than 95% of such cases. The purpose of this report is to provide recommendations for preventing Lyme disease, including the use of Lyme disease vaccine. Individuals can reduce their risk of Lyme diseas...

    journal_title:Pediatrics

    pub_type: 指南,杂志文章,实务指引,评审

    doi:

    authors:

    更新日期:2000-01-01 00:00:00

  • Enhancing developmentally oriented primary care: an Illinois initiative to increase developmental screening in medical homes.

    abstract::In 2005, the Enhancing Developmentally Oriented Primary Care (EDOPC) project of the Illinois chapter of the American Academy of Pediatrics and the Illinois Department of Healthcare and Family Services began a project to improve the delivery and financing of preventive health and developmental services for children in ...

    journal_title:Pediatrics

    pub_type: 杂志文章

    doi:10.1542/peds.2010-1466K

    authors: Allen SG,Berry AD,Brewster JA,Chalasani RK,Mack PK

    更新日期:2010-12-01 00:00:00