Sheeppox virus SPPV14 encodes a Bcl-2-like cell death inhibitor that counters a distinct set of mammalian proapoptotic proteins.

abstract：:Broad, multispecific CD4(+) and CD8(+) T-cell responses to the hepatitis C virus (HCV), as well as virus-cross-neutralizing antibodies, are associated with recovery from acute infection and may also be associated in chronic HCV patients with a favorable response to antiviral treatment. In order to recapitulate all of ...

journal_title：Journal of virology

authors： Lin Y,Kwon T,Polo J,Zhu YF,Coates S,Crawford K,Dong C,Wininger M,Hall J,Selby M,Coit D,Medina-Selby A,McCoin C,Ng P,Drane D,Chien D,Han J,Vajdy M,Houghton M

更新日期：2008-08-01 00:00:00

abstract：:Human parechoviruses (HPeV), members of the Parechovirus genus of Picornaviridae, are frequent pathogens but have been comparatively poorly studied, and little is known of their diversity, evolution, and molecular biology. To increase the amount of information available, we have analyzed 7 HPeV strains isolated in Cal...

journal_title：Journal of virology

authors： Al-Sunaidi M,Williams CH,Hughes PJ,Schnurr DP,Stanway G

更新日期：2007-01-01 00:00:00

abstract：:The origin and role of the endonuclease activity associated with purified virions of simian virus 40, previously described by this and other laboratories, have been further investigated. We found that the enzymatic activity from virions of temperature-sensitive (ts) mutants is not more heat labile than that from wild-...

journal_title：Journal of virology

authors： Dooley DC,Ryzlak MT,Ozer HL

更新日期：1976-02-01 00:00:00

abstract：:Rio Bravo virus (RBV) is a member of the family Flaviviridae, genus Flavivirus. It belongs to a group of viruses in the genus with no known vector. In this report, we analyze the complete genome of the prototype RBV, strain M64. ...

journal_title：Journal of virology

authors： Volkova E,Tesh RB,Monath TP,Vasilakis N

更新日期：2012-04-01 00:00:00

abstract：:From the results of transient plasmid-based replication assays, it has been postulated that homologous regions (hrs) of Autographa californica nuclear polyhedrosis virus (AcMNPV) function as origins of viral DNA replication. However, these assays vary in specificity according to the methodology used and may not be dep...

journal_title：Journal of virology

authors： Wu Y,Carstens EB

更新日期：1996-10-01 00:00:00

abstract：:Hepatitis C virus (HCV) infection causes not only intrahepatic diseases but also extrahepatic manifestations, including type 2 diabetes. We previously reported that HCV replication suppresses cellular glucose uptake by downregulation of cell surface expression of glucose transporter 2 (GLUT2) (D. Kasai et al., J. Hepa...

journal_title：Journal of virology

authors： Matsui C,Shoji I,Kaneda S,Sianipar IR,Deng L,Hotta H

更新日期：2012-12-01 00:00:00

abstract：:Noroviruses (NoVs) are a leading cause of gastroenteritis worldwide, yet host factors that restrict NoV replication are not well understood. Here, we use a CRISPR activation genome-wide screening to identify host genes that can inhibit murine norovirus (MNoV) replication in human cells. Our screens identified with hig...

journal_title：Journal of virology

authors： Orchard RC,Sullender ME,Dunlap BF,Balce DR,Doench JG,Virgin HW

更新日期：2018-12-10 00:00:00

abstract：:Transfection has been found and characterized in pneumococcus. For replicating omega3 phage DNA extracted from infected cells, transfection was relatively efficient and rose linearly with DNA concentration and quadratically with time, according to T(T - 3.5) min(2). For mature DNA extracted from phage particles, trans...

journal_title：Journal of virology

authors： Porter RD,Guild WR

更新日期：1978-01-01 00:00:00

abstract：:Increasing evidence suggests that the generation of cytotoxic T-lymphocyte (CTL) responses specific for a diversity of viral epitopes will be needed for an effective human immunodeficiency virus type 1 (HIV-1) vaccine. Here, we determine the frequencies of CTL responses specific for the simian immunodeficiency virus G...

journal_title：Journal of virology

authors： Barouch DH,Craiu A,Santra S,Egan MA,Schmitz JE,Kuroda MJ,Fu TM,Nam JH,Wyatt LS,Lifton MA,Krivulka GR,Nickerson CE,Lord CI,Moss B,Lewis MG,Hirsch VM,Shiver JW,Letvin NL

更新日期：2001-03-01 00:00:00

abstract：:The nucleotide sequences of the termini of the mature pseudorabies virus genome and of the junction between these termini in concatemeric DNA were compared. To ensure conservation of unmodified 5' and 3' termini, the end fragments obtained directly (uncloned) from mature viral DNA were sequenced. The sequence obtained...

journal_title：Journal of virology

authors： Harper L,Demarchi J,Ben-Porat T

更新日期：1986-12-01 00:00:00

abstract：UNLABELLED:Virus-like particles (VLPs) built on the Newcastle disease virus (NDV) core proteins, NP and M, and containing two chimeric proteins, F/F and H/G, composed of respiratory syncytial virus (RSV) fusion protein (F) and glycoprotein (G) ectodomains fused to the transmembrane and cytoplasmic domains of the NDV F ...

journal_title：Journal of virology

authors： McGinnes Cullen L,Schmidt MR,Kenward SA,Woodland RT,Morrison TG

更新日期：2015-07-01 00:00:00

abstract：:Human herpesvirus 8 (HHV-8) (also known as Kaposi's sarcoma-associated herpesvirus) encodes a novel noncoding polyadenylated nuclear (PAN) RNA (also known as T1.1 or nut-1) during the early phase of lytic replication. PAN RNA is the most abundant transcript of HHV-8, comprising 80% of total poly(A)-selected transcript...

journal_title：Journal of virology

authors： Song MJ,Brown HJ,Wu TT,Sun R

更新日期：2001-04-01 00:00:00

abstract：:Taking advantage of the wide tropism of baculoviruses (BVs), we constructed a recombinant BV (BV(CAR)) pseudotyped with human coxsackie B-adenovirus receptor (CAR), the high-affinity attachment receptor for adenovirus type 5 (Ad5), and used the strategy of piggybacking Ad5-green fluorescent protein (Ad5GFP) vector on ...

journal_title：Journal of virology

authors： Granio O,Porcherot M,Corjon S,Kitidee K,Henning P,Eljaafari A,Cimarelli A,Lindholm L,Miossec P,Boulanger P,Hong SS

更新日期：2009-06-01 00:00:00

abstract：:Intrarectal simian immunodeficiency virus (SIV) infection in rhesus macaques is a model for sexual transmission of primate retroviruses. Phylogenetic studies on envelope gene sequences that were present in blood following intrarectal SIV inoculation provided evidence for selective amplification of a subset of viruses ...

journal_title：Journal of virology

authors： Trivedi P,Horejsh D,Hinds SB,Hinds PW II,Wu MS,Salvato MS,Pauza CD

更新日期：1996-10-01 00:00:00

abstract：:Members of the apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC3 [A3]) family of DNA cytidine deaminases are intrinsic restriction factors against retroviruses. In felids such as the domestic cat (Felis catus), the A3 genes encode the A3Z2, A3Z3, and A3Z2Z3 antiviral cytidine deaminases. Only A3...

journal_title：Journal of virology

authors： Gu Q,Zhang Z,Gertzen CGW,Häussinger D,Gohlke H,Münk C

更新日期：2018-02-26 00:00:00

abstract：UNLABELLED:Enterovirus A71 (EV-A71) is a major cause of hand, foot, and mouth disease (HFMD) and is particularly prevalent in parts of Southeast Asia, affecting thousands of children and infants each year. Revealing the evolutionary and epidemiological dynamics of EV-A71 through time and space is central to understandi...

journal_title：Journal of virology

authors： Geoghegan JL,Tan le V,Kühnert D,Halpin RA,Lin X,Simenauer A,Akopov A,Das SR,Stockwell TB,Shrivastava S,Ngoc NM,Uyen le TT,Tuyen NT,Thanh TT,Hang VT,Qui PT,Hung NT,Khanh TH,Thinh le Q,Nhan le NT,Van HM,Viet do C

更新日期：2015-09-01 00:00:00

abstract：:Five hepatoma cell lines, including CZHC/8571, PLC/PRF/5, Hep3B, HepG2, and HUH7, were inoculated with three diverse isolates of human immunodeficiency virus type 1 (HIV-1). Productive infection was noted in all hepatoma cell lines, and expression of viral p24 antigen lasted for over 3 months, but its level decreased ...

journal_title：Journal of virology

authors： Cao YZ,Friedman-Kien AE,Huang YX,Li XL,Mirabile M,Moudgil T,Zucker-Franklin D,Ho DD

更新日期：1990-06-01 00:00:00

abstract：:Naked DNA vaccines expressing the prM and E genes of two tick-borne flaviviruses, Russian spring summer encephalitis (RSSE) virus and Central European encephalitis (CEE) virus were evaluated in mice. The vaccines were administered by particle bombardment of DNA-coated gold beads by Accell gene gun inoculation. Two imm...

journal_title：Journal of virology

authors： Schmaljohn C,Vanderzanden L,Bray M,Custer D,Meyer B,Li D,Rossi C,Fuller D,Fuller J,Haynes J,Huggins J

更新日期：1997-12-01 00:00:00

abstract：:The Tf1 retrotransposon of Schizosaccharomyces pombe represents a group of eukaryotic long terminal repeat (LTR) retroelements that, based on their sequences, were predicted to use an RNA self-primer for initiating reverse transcription while synthesizing the negative-sense DNA strand. This feature is substantially di...

journal_title：Journal of virology

authors： Hizi A

更新日期：2008-11-01 00:00:00

abstract：:Interferon regulatory factor 7 (IRF-7) is implicated in the regulation of Epstein-Barr virus (EBV) latency. EBV transforms primary B cells, and the major EBV oncoprotein, latent membrane protein 1 (LMP-1), is required for the process. LMP-1 both induces the expression of IRF-7 and activates the IRF-7 protein by phosph...

journal_title：Journal of virology

authors： Zhang L,Zhang J,Lambert Q,Der CJ,Del Valle L,Miklossy J,Khalili K,Zhou Y,Pagano JS

更新日期：2004-12-01 00:00:00

abstract：:Three plaque isolates of SV40 strain 777 and 1 plaque isolate of strain 776 were grown to high-titer stocks and serially passaged, undiluted, in monkey BS-C-1 cells. In each case, the serial passaging procedure resulted in the accumulation of closed-circular SV40 DNA molecules containing covalently linked sequences ho...

journal_title：Journal of virology

authors： Lavi S,Rozenblatt S,Singer MF,Winocour E

更新日期：1973-09-01 00:00:00

abstract：:Group A rotaviruses are major pathogens causing acute gastroenteritis in children and animals. To determine if group A rotavirus replicates and induces disease in rats, antibody-negative Lewis neonatal or adult rats were inoculated orally with tissue culture-adapted human (Wa, WI61, and HAL1166), simian (rhesus rotavi...

journal_title：Journal of virology

authors： Ciarlet M,Conner ME,Finegold MJ,Estes MK

更新日期：2002-01-01 00:00:00

abstract：:Primary human embryonic kidney (HEK) cells were transformed by a focus assay with BK virus (BKV) DNA molecularly cloned at its unique EcoRI site. Both viral DNA sequences and viral tumor antigens were present and expressed in all the foci that we examined. However, cells isolated from foci were incapable of growth in ...

journal_title：Journal of virology

authors： Pater A,Pater MM

更新日期：1986-05-01 00:00:00

abstract：:The envelope protein of human immunodeficiency virus type 1 HIV-1 undergoes proteolytic cleavage in the Golgi complex to produce subunits designated gp120 and gp41, which remain noncovalently associated. While gp41 has a well-characterized oligomeric structure, the maintenance of gp41-independent gp120 intersubunit co...

journal_title：Journal of virology

authors： Center RJ,Earl PL,Lebowitz J,Schuck P,Moss B

更新日期：2000-05-01 00:00:00

abstract：:The purpose of this study was to gain insights into the regulation of Epstein-Barr virus (EBV) gene transcription during the establishment of viral latency in B cells. During the early stages of EBV infection in B lymphocytes, transcription of six viral nuclear antigens (EBNAs) is initiated from an early promoter (Wp)...

journal_title：Journal of virology

authors： Schlager S,Speck SH,Woisetschläger M

更新日期：1996-06-01 00:00:00

abstract：UNLABELLED:While numerous viral microRNAs (miRNAs) expressed by DNA viruses, especially herpesvirus family members, have been reported, there have been very few reports of miRNAs derived from RNA viruses. Here we describe three miRNAs expressed by bovine foamy virus (BFV), a member of the spumavirus subfamily of retrov...

journal_title：Journal of virology

authors： Whisnant AW,Kehl T,Bao Q,Materniak M,Kuzmak J,Löchelt M,Cullen BR

更新日期：2014-05-01 00:00:00

abstract：:Measles is a highly contagious human disease caused by the measles virus (MeV). In this study, by proteomic analysis, we identified peroxiredoxin 1 (Prdx1) as a host factor that binds to the C-terminal region of the nucleoprotein (N; N(TAIL)) of MeV. Glutathione S-transferase (GST) pulldown experiments showed that the...

journal_title：Journal of virology

authors： Watanabe A,Yoneda M,Ikeda F,Sugai A,Sato H,Kai C

更新日期：2011-03-01 00:00:00

abstract：:Densonucleosis viruses 1 and 2 both contain the three polyamines putrescine, spermidine, and spermine in complete virus particles but not in their respective top components. The polyamines, with spermidine predominant, comprise 1.41% of the virus particle by weight, which is sufficient to neutralize 26% of the single-...

journal_title：Journal of virology

authors： Kelly DC,Elliott RM

更新日期：1977-01-01 00:00:00

abstract：:Human oncolytic adenoviruses have been used in clinical trials targeting cancers of epithelial origin. To gain a better understanding of the infectious cycle of adenovirus in normal human squamous tissues, we examined the viral infection process in organotypic cultures of primary human keratinocytes. We show that for ...

journal_title：Journal of virology

authors： Noya F,Balagué C,Banerjee NS,Curiel DT,Broker TR,Chow LT

更新日期：2003-06-01 00:00:00

abstract：:After rabies virus glycoprotein was treated with CNBr, the peptide mixture was fractionated by preparative sodium dodecyl sulfate-polyacrylamide gel electrophoresis. CNBr-cleaved peptide fragments were resolved into seven peptide bands under reducing conditions and six peptide bands under nonreducing conditions. The i...

journal_title：Journal of virology

authors： Dietzschold B,Wiktor TJ,Macfarlan R,Varrichio A

更新日期：1982-11-01 00:00:00