Detection of CD1 positive cells in the peripheral blood of patients suffering from cancer-associated malnutrition.

abstract：BACKGROUND:Infantile hemangiomas (IHs) are the most common benign tumors of childhood. They are characterized by a unique clinical course with two phases, proliferation and involution, which are followed by regression. The therapy of infantile hemangiomas was revolutionized in 2008 by the introduction of propranolol, h...

journal_title：Immunology letters

authors： Wnęk A,Andrzejewska E,Kobos J,Taran K,Przewratil P

更新日期：2017-05-01 00:00:00

abstract：:Phagocytosis of latex beads by peritoneal macrophages was examined by means of flow cytometry (FCM). This assay revealed that adrenocorticotropic hormone (ACTH) suppressed phagocytosis in a dose-dependent manner. ACTH (1-24) was more suppressive than ACTH (1-39). Control phagocytosis was partially suppressed in Ca(2+)...

journal_title：Immunology letters

authors： Ichinose M,Sawada M,Maeno T

更新日期：1994-10-01 00:00:00

abstract：:Previously we reported that a mega-dose of Vitamin C enhanced the initial stage of delayed-type hypersensitivity reaction in Balb/c mice. In this study its effects were further evaluated as follows. Mice were administered Vitamin C intraperitoneally at 0.625 mg/day or at 5mg/day for variable days before, during, or af...

journal_title：Immunology letters

authors： Noh K,Lim H,Moon SK,Kang JS,Lee WJ,Lee D,Hwang YI

更新日期：2005-04-15 00:00:00

abstract：:Within the 3' end of nucleotide sequence of human adult T-cell leukaemia virus (ATLV) four small open frames in various phases were found previously. The frames code for 10,000-, 11,000-, 12,000- and 27,000-dalton polypeptides, one of which can be responsible for virus transforming activity. By means of methods of pre...

journal_title：Immunology letters

authors： Zav'yalov VP,Denesyuk AI

更新日期：1987-01-01 00:00:00

abstract：:Diabetes mellitus is associated with an increased incidence of cardiovascular events and microvascular complications. Serum amyloid A (SAA), a HDL apolipoprotein is a risk marker for cardiovascular disease. A permanent increase in SAA plasma levels is observed in diabetics. Because SAA acts on leukocytes, we evaluated...

journal_title：Immunology letters

authors： Hatanaka E,Monteagudo PT,Marrocos MS,Campa A

更新日期：2007-02-15 00:00:00

abstract：:Natural levels of goat antiphosphorylethanolamine (anti-PE) antibodies decreased after injection of purified human C-reactive protein (CRP). The concentration of anti-CRP antibodies followed a continuous increment from non-detectable levels to a plateau at 80 days after first injection. ...

journal_title：Immunology letters

authors： Coll JM

更新日期：1988-05-01 00:00:00

abstract：:The aim of the present work was to develop an in vitro model of eosinophil cytotoxicity which mimics numerous in vivo situations characterized by complement activation through the alternative pathway. Our results demonstrate that eosinophilic granulocytes from patients with parasitic diseases and blood eosinophilia we...

journal_title：Immunology letters

authors： De Simone C,Ferrari M,Pugnaloni L,Ferrarelli G,Rumi C,Sorice F

更新日期：1986-01-01 00:00:00

abstract：:As shown earlier, the cells transformed in vitro by several different oncogenes, or spontaneously, during in vivo growth in normal hosts would be gradually replaced by the highly-tumorigenic descendants co-expressing high H2O2-catabolizing and PGE2-releasing activities. Acquisition of (H2O2(CA) + PGE(S)) phenotype pro...

journal_title：Immunology letters

authors： Deichman G,Dyakova N,Kashkina L,Matveeva V,Uvarova E

更新日期：1999-10-01 00:00:00

abstract：:In this study, we examined the cytokine production by human peripheral blood mononuclear cells (PBM) from recipients of orthotopic liver transplants which had been stimulated by donor-specific alloantigen. Levels of interleukin (IL)-2, IL-4, interferon (IFN)-gamma, IL-10 and transforming growth factor (TGF)-beta produ...

journal_title：Immunology letters

authors： Chung SW,Yoshida EM,Cattral MS,Hu Y,Gorczynski RM

更新日期：1998-09-01 00:00:00

abstract：:NK-like T cells which express the NK1.1 molecule and CD3 (or TCR) of intermediate level (CD3int or TCRint cells) were recently demonstrated to be present in various immune organs, and to have NK-like cytotoxic activity against NK target cells. In this study, we investigated whether NK1.1- T cells could express NK1.1. ...

journal_title：Immunology letters

authors： Ikarashi Y,Maruoka H,Shinohara K,Sugimura T,Terada M,Wakasugi H

更新日期：1998-04-01 00:00:00

abstract：BACKGROUND:Omalizumab therapy was found to be safe and effective as an add-on therapy for patients with poorly controlled severe asthma. Although several studies over the last decade have demonstrated its efficacy in other Immunoglobulin E related diseases, its use in such conditions is off-label. OBJECTIVE:This study...

journal_title：Immunology letters

authors： Cavaliere C,Begvarfaj E,Incorvaia C,Sposato B,Brunori M,Ciofalo A,Greco A,de Vincentiis M,Masieri S

更新日期：2020-11-01 00:00:00

abstract：:Others have reported that a monoclonal anti-human IL-2 receptor antibody (anti-CD25) specifically binds a membrane receptor on Xenopus laevis PHA-induced and paraformaldehyde-fixed splenic blasts. In this paper, we present evidence suggesting that this binding is an artifact of membrane damage. Specifically, significa...

journal_title：Immunology letters

authors： Haynes L,Moynihan JA,Cohen N

更新日期：1990-12-01 00:00:00

abstract：:Wnt5a is a secreted pleiotropic glycoprotein produced in an inflammatory state by a wide spectrum of ubiquitous cell populations. Recently, we demonstrated that Wnt5a skews the differentiation of human monocyte derived dendritic cells (moDCs) to a tolerogenic functional state. In this study we focus our interest on th...

journal_title：Immunology letters

authors： Valencia J,Martínez VG,Hidalgo L,Hernández-López C,Canseco NM,Vicente A,Varas A,Sacedón R

更新日期：2014-11-01 00:00:00

abstract：:Whilst many physiological functions of nitric oxide (NO) have been revealed so far, recent evidence proposes an essential role for NO in T lymphocyte activation and signal transduction. NO acts as a second messenger, activating soluble guanyl cyclase and participating in signal transduction pathways involving cyclic G...

journal_title：Immunology letters

authors： Nagy G,Clark JM,Buzás EI,Gorman CL,Cope AP

更新日期：2007-07-31 00:00:00

abstract：:In the current study, the possible association of positivity (POS), recently defined as general disposition to view life under positive outlook, with immune markers and post-stress modifications, was analyzed. Circulating lymphocyte subsets and serum cytokine levels were evaluated before and after a standard mild acut...

journal_title：Immunology letters

authors： Caprara GV,Nisini R,Castellani V,Vittorio P,Alessandri G,Vincenzo Z,Claudia F,Valentina G,Andrea PD,Biondo MI,Milanetti F,Salerno G,Vincenzo V,Mario P,Aniballi E,Simonetta S,Angela S,D'Amelio R

更新日期：2017-08-01 00:00:00

abstract：:Four murine monoclonal antibodies (mAbs) showing similar reactivity with a cell-wall extract and mannan preparation obtained from Candida albicans were examined for epitope specificity. An enzyme-linked immunosorbent assay (ELISA) was used to determine total mAb binding to extracted cell-wall antigen when each mAb was...

journal_title：Immunology letters

authors： Chaffin WL,Morrow KJ Jr

更新日期：1989-07-01 00:00:00

abstract：:Pertussis, or whooping cough, has recently reemerged as a major public health threat despite high levels of vaccination. The development of a novel pertussis vaccine, especially an intranasal (i.n.) vaccine is undoubtedly necessary, and mucosal adjuvants have been explored to enhance the immune response. In the presen...

journal_title：Immunology letters

authors： Shi W,Kou Y,Jiang H,Gao F,Kong W,Su W,Xu F,Jiang C

更新日期：2018-06-01 00:00:00

abstract：:A direct role for delayed hypersensitivity in organized granuloma formation has been emphasized in the literature, but some clinical and experimental studies have suggested a more complicated relationship. In order to further evaluate T-cell function in cutaneous granulomatous inflammation, hepatic granulomas isolated...

journal_title：Immunology letters

authors： Epstein WL,Okamoto M,Suya H,Fukuyama K

更新日期：1986-11-17 00:00:00

abstract：:Mature B cells express a single immunoglobulin Fc receptor, FcgammaRIIB, that functions to block downstream signaling by co-aggregated antigen receptors. Co-aggregation of receptors is essential because BCR activated kinases must phosphorylate FcgammaRIIB to recruit SHIP and mediate inhibitory signals. Pre-B cells als...

journal_title：Immunology letters

authors： Brauweiler AM,Cambier JC

更新日期：2004-03-29 00:00:00

abstract：:Immunodeficiencies can lead to alterations of the gut microbiome that render it pathogenic and capable of transmitting disease to naïve hosts. Here, we review the role of Toll-like receptor (TLR) 5, the innate receptor for bacterial flagellin, in immune responses to the normal gut microbiota with a focus its role on a...

journal_title：Immunology letters

authors： Leifer CA,McConkey C,Li S,Chassaing B,Gewirtz AT,Ley RE

更新日期：2014-12-01 00:00:00

abstract：:Alpha-fetoprotein (AFP), an onco-fetal protein which binds specifically polyunsaturated fatty acids, has been shown to modulate arachidonic acid metabolism in a human T-cell line. In Jurkat lymphoma cells, AFP decreases the synthesis of prostaglandins and increases the release of arachidonic acid and leukotrienes. The...

journal_title：Immunology letters

authors： Aussel C,Fehlmann M

更新日期：1987-01-01 00:00:00

abstract：:The surface phenotypes of lymphoid cells in the developing embryonic thymus were characterized by using monoclonal antibodies. FT-2 antigen thus defined was predominantly expressed on thymocytes in the earlier embryonic stages in all the inbred mouse strains tested. The immunofluorescence and immunoperoxidase tests in...

journal_title：Immunology letters

authors： Takashi T,Kasai M,Tanaka N,Takahashi T,Tokunaga T

更新日期：1985-01-01 00:00:00

abstract：:Despite the prominent progress in understanding cancer immunosurveillance mechanisms, there are some types of problems which have been identified to hinder effective and successful immunotherapy of cancers. Such problems have been ascribed to the tumor abilities in the creation of a tolerant milieu that can impair imm...

journal_title：Immunology letters

authors： Bahrambeigi S,Molaparast M,Sohrabi F,Seifi L,Faraji A,Fani S,Shafiei-Irannejad V

更新日期：2020-04-01 00:00:00

abstract：:In addition to its hematopoietic activities, interleukin-3 (IL-3) can modulate macrophage functions. We have studied the production of interleukin-1 (IL-1), interleukin-6 (IL-6) and tumor necrosis factor (TNF) by mouse peritoneal macrophages triggered by lipopolysaccharide (LPS) in the presence or absence of IL-3. Int...

journal_title：Immunology letters

authors： Cohen L,David B,Cavaillon JM

更新日期：1991-05-01 00:00:00

abstract：:Recent data have shown that piperlongumine (PL), an important component of Piper longum fruits, is known to possess anti-inflammatory and vascular-protective activities. This study aimed to examine the therapeutic effects and underlying mechanisms of PL on lupus-prone MRL-Fas(lpr) mice. Female MRL-Fas(lpr) mice were i...

journal_title：Immunology letters

authors： Yao L,Chen HP,Ma Q

更新日期：2014-09-01 00:00:00

abstract：:The production of interleukin 1 (IL-1) by lipopolysaccharide (LPS)-stimulated myelomonocytic cell lines ML-1, THP-1 and PL-21 was significantly enhanced by the addition of insulin, insulin-like growth factor (IGF)-I or IGF-II into the cell cultures. The IL-1 activity in the supernatants from cell cultures stimulated w...

journal_title：Immunology letters

authors： Holán V,Minowada J

更新日期：1992-12-01 00:00:00

abstract：:The antigen receptors on the surface of B- and T-lymphocytes are complexes of several integral membrane proteins, essential for their proper expression and function. Recent studies demonstrated that transmembrane (TM) domains of the components of these receptors play a critical role in their association and function. ...

journal_title：Immunology letters

authors： Zidovetzki R,Rost B,Pecht I

更新日期：1998-12-01 00:00:00

abstract：:Wistar rats submitted to 3 intravenous (i.v.) or intraperitoneal (i.p.) immunizations with saline extract of rat male accessory glands (RAG) associated to liposomes developed a delayed type hypersensitivity (DTH) response to RAG after the first immunization, a remission state after the second immunization and a specif...

journal_title：Immunology letters

authors： Correa SG,Riera CM

更新日期：1991-04-01 00:00:00

abstract：:Human natural killer (NK) cell activity was not significantly affected by leukotriene (LT) B4 over a wide concentration range (10(-6)-10(-14) M), whether added directly to the NK cell assay or after preincubation of effector cells for 2 h with the drug before addition of Cr labelled K562 target cells. In addition, LTB...

journal_title：Immunology letters

authors： Hall TJ,Brostoff J

更新日期：1985-01-01 00:00:00

abstract：:The murine pre-B-like cell line, 70Z /3, has been shown to undergo differentiation in response to supernatants derived from concanavalin-A (Con A) stimulated rat spleen cells or ultraviolet light treated P388D1 macrophage cell line. After culture for 24 h with supernatant factors, normally membrane IgM negative 70Z /3...

journal_title：Immunology letters

authors： Stanton T,Maynard M

更新日期：1984-01-01 00:00:00