Mesangial IgA deposits in two patients with AIDS-related complex.

abstract：:X-linked nephrogenic diabetes insipidus (NDI) is a rare disease caused by mutations in the vasopressin V2 receptor (AVPR2) gene. We analyzed the AVPR2 gene in 6 unrelated Korean families with X-linked NDI, and found 6 novel mutations. Two of them were missense point mutations, 2 were short deletions causing frameshift...

journal_title：Nephron

authors： Cheong HI,Park HW,Ha IS,Moon HN,Choi Y,Ko KW,Jun JK

更新日期：1997-01-01 00:00:00

abstract：:Serum apolipoproteins A (Apo-A) and B (Apo-B) and lecithin: cholesterol acyl transferase (LCAT) activities and 24-hour urinary cholesterol levels were estimated in 25 nephrotic children before and during steroid treatment with 4 weeks of daily prednisolone followed by another 4 weeks of alternate-day prednisolone. The...

journal_title：Nephron

authors： Nayak SS,Bhaskaranand N,Kamath KS,Baliga M,Venkatesh A,Aroor AR

更新日期：1990-01-01 00:00:00

abstract：:Spontaneous allograft rupture after kidney transplantation is a rare complication usually due to an acute rejection of the interstitial type. In a 32-year-old man kidney transplantation was performed under immunosuppression with prednisolone and ciclosporin (CS). The dose of CS was 5 mg/kg body weight intravenously fo...

journal_title：Nephron

authors： Biesenbach G,Zazgornik J,Kaiser W,Grafinger P,Stuby U,Gross C,Hartl P,Brücke P

更新日期：1992-01-01 00:00:00

abstract：:A case of isolated ACTH deficiency with hyporeninemic hypoaldosteronism, presenting severe hyponatremia, is described. A 57-year-old man complaining of nausea, vomiting and fatigability was admitted to our hospital because of hyponatremia (114 mEq/I). The low levels of serum cortisol and urinary 17-OHCS suggested gluc...

journal_title：Nephron

authors： Okada K,Takahashi S

更新日期：1996-01-01 00:00:00

abstract：:In vitro formation of prostaglandins (PG) E2, F2 alpha, 6-keto-F1 alpha, and thromboxane B2 (TxB2) by glomeruli from rats with reduced renal mass (RRM) were evaluated by radioimmunoassay. Four weeks following ablation of renal mass, PGE2, PGF2 alpha, and TxB2 production by glomeruli from RRM rats was significantly gre...

journal_title：Nephron

authors： Stahl RA,Kudelka S,Paravicini M,Schollmeyer P

更新日期：1986-01-01 00:00:00

abstract：:In order to estimate a regenerative response in the early phase after renal ischemia-reperfusion in rat, we examined the time course of the activation of epidermal growth factor receptor (EGFR) as a response of signal transduction pathway after 45 min ischemia in kidney. The activation of EGFR was observed 5-30 min af...

journal_title：Nephron

authors： Yano T,Yazima S,Hagiwara K,Ozasa H,Ishizuka S,Horikawa S

更新日期：1999-02-01 00:00:00

abstract：:The effects of chitosan-coated dialdehyde cellulose (chitosan DAC), a newly developed oral adsorbent for urea and ammonia, were examined in a glomerulonephritis model in rats. Mesangial proliferative glomerulonephritis accompanied with proteinuria was induced by an intravenous injection of anti-rat Thy-1.1 monoclonal ...

journal_title：Nephron

authors： Yagi M,Kato S,Nishitoba T,Sato H,Kobayashi N,Iinuma N,Nagano N

更新日期：1998-01-01 00:00:00

abstract：:The present study was aimed to determine the effect of caffeine on the development of renal hypertension. Two-kidney, 1-clip (2K1C) hypertension and deoxycorticosterone acetate (DOCA, 200 mg/kg, subcutaneous implantation)-salt (0.9% NaCl drinking) hypertension were instituted in Sprague-Dawley rats. They were then gro...

journal_title：Nephron

authors： Choi KC,Lee J,Moon KH,Park KK,Kim SW,Kim NH

更新日期：1993-01-01 00:00:00

abstract：:Assessment of kidney function is primarily based on urine output and Creatinine (Cr)-based methods to estimate glomerular filtration rate (GFR). The latter is confounded as Cr is not exclusively filtered by the kidney and rises relatively late after the onset of acute kidney injury (AKI). This leads to delays in recog...

journal_title：Nephron

authors： Khorashadi M,Beunders R,Pickkers P,Legrand M

更新日期：2020-01-01 00:00:00

abstract：:Mizoribine has been shown to possess an immunosuppressive action that inhibits the proliferation of lymphocytes selectively by interfering with inosine monophosphate dehydrogenase. Recent studies have demonstrated that mizoribine improves renal tubulointerstitial fibrosis in the rat model of unilateral ureteral obstru...

journal_title：Nephron

authors： Sato N,Shiraiwa K,Kai K,Watanabe A,Ogawa S,Kobayashi Y,Yamagishi-Imai H,Utsunomiya Y,Mitarai T

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Several studies have provided convincing evidence that in apparently healthy subjects elevated serum levels of plasma C-reactive protein (CRP) are associated with an increased risk of experiencing myocardial infarction and sudden cardiac death. It has been claimed that, in dialytic patients, the hepatic synt...

journal_title：Nephron

authors： Panichi V,Migliori M,De Pietro S,Taccola D,Bianchi AM,Giovannini L,Norpoth M,Metelli MR,Cristofani R,Bertelli AA,Sbragia G,Tetta C,Palla R,Colombo R

更新日期：2002-08-01 00:00:00

abstract：:Results from many laboratories, including our own, support the following view of the status of renal blood flow (RBF) in acute renal failure (ARF). During the initiation phase of virtually all forms of experimental ARF, RBF appears to be substantially decreased. The mechanisms for the decrease in RBF vary depending on...

journal_title：Nephron

authors： Hsu CH,Kurtz TW

更新日期：1981-01-01 00:00:00

abstract：:The urinary transforming growth factor beta (TGF-beta) excretion was measured in 33 patients including 10 with systemic lupus erythematosus (SLE), 8 with focal glomerular sclerosis (FGS), 9 with IgA nephropathy (IgAN), and 6 with membranous nephropathy (MN), and in 7 healthy subjects by enzyme-linked immunosorbent ass...

journal_title：Nephron

authors： Kanai H,Mitsuhashi H,Ono K,Yano S,Naruse T

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND/AIMS:Enamel-renal syndrome is characterized by nephrocalcinosis, enamel defects, gingival hyperplasia and eruption failures. It has been recently identified that recessive mutations in the FAM20A gene result in amelogenesis imperfecta (AI)-gingival fibromatosis. The aim of this research to determine whether ...

journal_title：Nephron

authors： Koruyucu M,Seymen F,Gencay G,Gencay K,Tuna EB,Shin TJ,Hyun HK,Kim YJ,Kim JW

更新日期：2018-01-01 00:00:00

abstract：:The concentration changes, during hemodialysis treatment, of 18 characteristic uremia compounds, analyzed by high-pressure liquid chromatography in sera of renal patients were studied. Pre- to postdialysis concentration ratios (dialysis ratio, D) varied from 0.83 to 3.04 for the different solutes. A division into thre...

journal_title：Nephron

authors： Schoots AC,Peeters JA,Gerlag PG

更新日期：1989-01-01 00:00:00

abstract：:Platelet activation is commonly monitored with a battery of monoclonal antibodies against different platelet epitopes with controversial results. The transient expression of platelet markers and their role mediating interactions with other cells could easily explain these discrepancies. The present study has evaluated...

journal_title：Nephron

authors： Hernández MR,Galán AM,Lozano M,Bozzo J,Cases A,Escolar G,Calls J,Ordinas A

更新日期：1998-10-01 00:00:00

abstract：OBJECTIVE:To develop and internally validate a multivariable prediction model based on simple clinical record data and laboratory tests and to estimate the probability of left-ventricular diastolic dysfunction (LVDD) in stable maintenance hemodialysis (MHD) patients without clinical heart failure. DESIGN:Cross-section...

journal_title：Nephron

authors： Sun L,Ji Y,Wang Y,Zhu D,Chen F,Zhang N,Shen E,Wang X

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND/AIMS:Fatigue is a common symptom in patients receiving hemodialysis (HD) and is generally associated with anemia. However, it can be difficult to resolve, even when anemia has been treated using erythropoiesis-stimulating agents and iron replacement therapy. In the present study, we examined the associations...

journal_title：Nephron

authors： Yamasaki A,Yoda K,Koyama H,Yamada S,Tsujimoto Y,Okuno S,Okada S,Inaba M

更新日期：2016-01-01 00:00:00

abstract：:We followed renal function through the natriuretic phase of 6 occasions of drug-induced recovery from minimal lesions nephrotic syndrome (MLNS). Protein excretion started to fall 1-3 days prior to the start of the natriuresis. The natriuresis was accompanied by a rise in glomerular filtration rate (GFR, inulin clearan...

journal_title：Nephron

authors： Koomans HA,Boer WH,Dorhout Mees EJ

更新日期：1987-01-01 00:00:00

abstract：:Isolated hindquarters of bilaterally nephrectomized and sham-operated rats were perfused in the presence and absence of 14C-labelled serine, respectively. After a perfusion period of 30 min 14C-serine was 4,074 +/- 270 dpm/ml in the perfusion medium of sham-operated animals and decreased to 2,800 +/- 190 dpm/ml in the...

journal_title：Nephron

authors： Djovkar A,Hörl WH,Heidland A

更新日期：1983-01-01 00:00:00

abstract：:The effect of imidazole-2-hydroxibenzoate on urinary excretion rates of glycosaminoglycans and albumin in 22 insulin-dependent diabetics with albumin excretion rates under 300 mg/day was evaluated in a 165-day double blind crossover study. Unlike placebo, the drug reduced glycosaminoglycan and albumin excretion rates ...

journal_title：Nephron

authors： Baggio B,Briani G,Cicerello E,Gambaro G,Giorato C,Iori E,Lavagnini T,Crepaldi G

更新日期：1988-01-01 00:00:00

abstract：:As the nephron population diminishes and azotemia develops, each remaining nephron adapts and increases its function by as much as 80%. To determine whether this adaption is permanent or transient, a rat model utilizing one remnant kidney and one normal control kidney was used. In stage one, immediately after ligation...

journal_title：Nephron

authors： Shankel SW,McDaniel J

更新日期：1982-01-01 00:00:00

abstract：:Diffuse crescentic glomerulonephritis was observed in a 40-year-old male patient who had a ventriculoatrial shunt implanted after a traffic accident 10 years previously. Immediately after treatment with immunosuppressants and plasma pheresis, signs of meningitis and septicemia developed. The responsible organism isola...

journal_title：Nephron

authors： Wakabayashi Y,Kobayashi Y,Shigematsu H

更新日期：1985-01-01 00:00:00

abstract：:Calcitonin, whatever its origin, produces a decrease in the renal tubular reabsorption of sodium, phosphate and calcium in man and in the rat. Renal receptors for calcitonin have been demonstrated in the membranes of rat tubular cells using 125I salmon calcitonin as a tracer. Hormone-receptor interaction initiates the...

journal_title：Nephron

authors： Ardaillou R

更新日期：1975-01-01 00:00:00

abstract：:Chronic kidney disease (CKD) is a worldwide public health problem associated with a high prevalence of cardiovascular disease (CVD) and impaired quality of life. Previous research for preventing loss of glomerular filtration rate (GFR) has focused on reducing blood pressure (BP) and proteinuria. Angiotensin converting...

journal_title：Nephron

authors： Ahmed A,Jorna T,Bhandari S

更新日期：2016-01-01 00:00:00

abstract：:The Spanish brush goat (Capra hiricus) was studied as an animal model for the anephric state. This rugged animal has a hardy appetite and offers ready blood access for dialysis and sampling. BUN, plasma creatinine and potassium could be brought to normal values by daily hemodialysis. Continual weight loss, severe anem...

journal_title：Nephron

authors： Bower JD,Holbert RD,Pearson JE,Jones Q,Bengis R,Berndt WO

更新日期：1980-01-01 00:00:00

abstract：INTRODUCTION:Control of hyperphosphatemia in patients on dialysis remains a major challenge. OBJECTIVE:This study evaluated predictors of serum phosphorus (sP) control among dialysis patients treated with noncalcium, oral phosphate binder therapy in a phase 3 clinical trial. METHODS:Post hoc analyses were performed u...

journal_title：Nephron

authors： Covic AC,Sprague SM,Rastogi A,Ketteler M,Walpen S,Perrin A,Floege J

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND/AIMS:Renal function deteriorates with age, but a few studies have addressed this longitudinally in elderly women. Our objective was, using 5 estimated glomerular filtration rates (eGFR)-equations, to evaluate changes in renal function and association with adverse outcomes for a decade in 75-year-old women. ...

journal_title：Nephron

authors： Malmgren L,McGuigan FE,Berglundh S,Westman K,Christensson A,Åkesson K

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Urinary neutrophil gelatinase associated lipocalin (uNGAL) and urinary kidney injury molecule-1 (uKIM-1) are markers of acute kidney injury. The albuminuria is a well-known abnormality after physical exercise. The aim of this study was to investigate changes in uNGAL and uKIM-1 after intensive exerc...

journal_title：Nephron

authors： Wołyniec W,Ratkowski W,Urbański R,Bartoszewicz M,Siluk D,Wołyniec Z,Kasprowicz K,Zorena K,Renke M

更新日期：2018-01-01 00:00:00

abstract：INTRODUCTION:Little is known about the effect of posttransplant opioid use on adherence to immunosuppressant therapy (IST) among adult renal transplant recipients (RTRs). OBJECTIVE:The aim of this study was to examine the relationship between opioid use and IST adherence among adult RTRs during the first year posttran...

journal_title：Nephron

authors： Chisholm-Burns MA,Spivey CA,Potukuchi PK,Streja E,Kalantar-Zadeh K,Kovesdy CP,Molnar MZ

更新日期：2020-01-01 00:00:00