Prostaglandin and thromboxane formation in glomeruli from rats with reduced renal mass.

abstract：:The 24-hour urinary excretion of kallikrein (K) and prostaglandin E2 (PGE2), which reflects their intrarenal synthesis, was measured in 7 normal women (NW), 10 women with essential hypertension (EH), 26 normal pregnant women (NP), 12 women with hypertension in pregnancy (HP), and 4 women with toxemia. All pregnant wom...

journal_title：Nephron

authors： Kovatz S,Arber I,Korzets Z,Rathaus M,Ben Aderet N,Bernheim J

更新日期：1985-01-01 00:00:00

abstract：:Kidney biopsy remains the gold standard for uncovering the pathogenesis of acute and chronic kidney diseases. However, the ability to perform high resolution, quantitative, molecular and cellular interrogation of this precious tissue is still at a developing stage compared to other fields such as oncology. Here, we di...

journal_title：Nephron

authors： Winfree S,Dagher PC,Dunn KW,Eadon MT,Ferkowicz M,Barwinska D,Kelly KJ,Sutton TA,El-Achkar TM

更新日期：2018-01-01 00:00:00

abstract：:A 4-year-old girl, who had been in perfect health, presented with the acute onset of renal failure and abdominal mass. Investigations revealed a solitary left kidney which on histology had the typical features of xanthogranulomatous pyelonephritis. The child had no previous history suggestive of chronic renal disease ...

journal_title：Nephron

authors： Noah M,Schoeneman MJ,Haycock G,Levitt SB,Bennett B,Greifer I

更新日期：1978-01-01 00:00:00

abstract：:Prolongation of repolarization dispersion (QT interval dispersion) measured from the 12-lead surface ECG has been associated with sudden cardiac death and ventricular tachyarrhythmias in a variety of cardiac disorders. The aim of our study was to assess the effects of hemodialysis (HD) and continuous ambulatory perito...

journal_title：Nephron

authors： Kantarci G,Ozener C,Tokay S,Bihorac A,Akoğlu E

更新日期：2002-08-01 00:00:00

abstract：:Several underlying metabolic abnormalities may be present in patients with recurrent calcium calculus disease (RCCD). The aim of this study was to determine the prevalence of deficiencies of 2 well-known potent inhibitors of crystal formation and growth, citrate and pyrophosphate, in the various metabolic subgroups an...

journal_title：Nephron

authors： Laminski NA,Meyers AM,Sonnekus MI,Smyth AE

更新日期：1990-01-01 00:00:00

abstract：:Recent studies have shown that the mass transfer coefficients (MTC) for low- and middle-molecular-weight substances are maintained at medium terms in patients under continuous ambulatory peritoneal dialysis (CAPD) therapy. We have studied the MTC for parathormone (MW 5,500-6,000) in 29 patients under CAPD. 11 patients...

journal_title：Nephron

authors： Rodríguez-Carmona A,Selgas R,Martínez ME,Ortí F,Miguel JL,Salinas M,Riñón C,Sánchez-Sicilia L

更新日期：1984-01-01 00:00:00

abstract：:Urate deposits within microtophi were found in 8% of unselected autopsies in Brisbane, Australia. Significant association were demonstrated with (a) a history of gouty arthritis and (b) the existence of nitrogen retention and renal disease of apparently primary, but not gouty, origin. However, in 26% of the patients, ...

journal_title：Nephron

authors： Linnane JW,Burry AF,Emmerson BT

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND:Complement factor H (hCFH) plays a key inhibitory role in the control of the alternative complement pathway. We examined whether urinary hCFH (U-hCFH) levels is useful as an indirect indicator of renal damage. METHODS:Urine samples were obtained from 104 patients with renal disease. Urine was collected with...

journal_title：Nephron

authors： Tamano M,Fuke Y,Endo M,Ohsawa I,Fujita T,Ohi H

更新日期：2002-01-01 00:00:00

abstract：:We studied complexes composed of C1q and beta 2-microglobulin (C1q.beta 2M) or serum amyloid P-component (C1q.SAP) in the sera of 38 patients receiving hemodialysis (HD) and 20 healthy control subjects using an enzyme-linked immunoassay. We also compared complex levels in HD patients with and without symptoms of HD-as...

journal_title：Nephron

authors： Hasegawa M,Kawashima S,Shikano M,Kojima K,Yanai T,Hassegawa H,Tomita M,Murakami K,Kawamura N,Katsumata H

更新日期：1995-01-01 00:00:00

abstract：:In order to elucidate the cells produced from human glomerular cultures, a pre-embedding ultrastructural immunoperoxidase technique was developed to investigate the precise localisation of a panel of monoclonal antibodies specific to human glomerular antigens in situ and used to identify the same antigens in vitro. Th...

journal_title：Nephron

authors： Jackson AE,Atkins RC,Glasgow EF

更新日期：1989-01-01 00:00:00

abstract：:The expression of the adhesion molecules LFA-1 (CD11a-CD18), Mac-1 (CD11b-CD18), and LAM-1 on predialysis and intradialysis neutrophils (PMN) was analyzed by flow cytometry in 10 chronic hemodialysis patients (CHD) and compared with age-matched normal controls. All patients were dialyzed either with a polyacrylonitril...

journal_title：Nephron

authors： Zachée P,Daelemans R,Pollaris P,Boogaerts MA,Lins RL

更新日期：1994-01-01 00:00:00

abstract：:The Center for Devices and Radiological Health, in collaboration with the Department of Veterans Affairs Medical Center, Brooklyn, N.Y., conducted a multi-center, multi-institutional study of the seroprevalence of antibodies to the human immunodeficiency virus (HIV) among dialysis workers. Seven dialysis units and 112...

journal_title：Nephron

authors： Berlyne G,Kaczmarek RG,Hamburger S,Hamilton P,Moore RM Jr,Charney AN,Kahn T,Gruber M,Kaufman CE,Goffinet J

更新日期：1992-01-01 00:00:00

abstract：:Hyaluronic acid (HA) is a ubiquitous component of extracellular matrix. After tissue injury, HA appears in greater abundance during the inflammatory response and the phase of clearance of cell and matrix debris, before collagen production and matrix degradation. The aim of this study was to examine whether normal rat ...

journal_title：Nephron

authors： Pedagogos E,Hewitson TD,Nicholls KM,Becker GJ

更新日期：2001-08-01 00:00:00

abstract：:Plasma and urine beta-2-microglobulin (B2m) were measured in 37 renal transplant recipients and 34 healthy subjects. Serum B2m was found to be a more sensitive index of renal function than serum creatinine. Renal transplant recipients had significantly higher urine B2m when compared with normal controls. Normal subjec...

journal_title：Nephron

authors： Woo KT,Lee EJ,Lau YK,Lim CH

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Glucose degradation products (GDPs) in peritoneal dialysis (PD) solution (PDS) have been shown to inflict damage to the kidney, which is the major organ for advanced glycosylation end product elimination. Hence, this study investigated whether new PDSs with neutral pH and low-GDPs have a beneficial effect on...

journal_title：Nephron

authors： Wang J,Zhu N,Yuan W

更新日期：2015-01-01 00:00:00

abstract：:Two observers, unaware of each other's findings and of the diagnosis, examined red cells in the urine of 109 patients by phase-contrast microscopy. All specimens were examined uncentrifuged by inverted microscopy, and 48 of the 109 were also examined under a light microscope after centrifugation. We were unable to con...

journal_title：Nephron

authors： Venkat Raman G,Pead L,Lee HA,Maskell R

更新日期：1986-01-01 00:00:00

abstract：:We describe a pair of 17-year-old identical twin brothers with asymptomatic proteinuria, one of whom showed focal segmental glomerulosclerosis (FSGS) while the other showed immunoglobulin M (IgM) nephropathy. For each twin, audiological examination was normal. There was no family history of renal failure, deafness, or...

journal_title：Nephron

authors： Kim HY,Oh H,Lee YH,Huh W,Kim YG,Kim DJ,Ko YH,Kim MK

更新日期：1999-06-01 00:00:00

abstract：:By April 26, 2020, infections related to coronavirus disease 2019 (COVID-19) affected people from 210 countries and caused 203,818 reported deaths worldwide. A few studies discussed the outcome of COVID-19 in kidney transplant recipients. This short series demonstrates our experience in managing COVID-19 disease in re...

journal_title：Nephron

authors： Elhadedy MA,Marie Y,Halawa A

更新日期：2020-12-08 00:00:00

abstract：:The size distribution pattern of circulating rPRL was studied in intact control (C) rats and in three uremic models, namely urine autoinfusion (UA), bilateral ureteral ligation (BUL), and bilateral nephrectomy (BNx). Plasmas were chromatographed by gel filtration in Sephadex G-100. Rat PRL was measured by RIA. The rPR...

journal_title：Nephron

authors： Martin-Oar JE,Cachofeiro MV,Rodriguez-Puyol D,Hernando L,López-Novoa JM

更新日期：1984-01-01 00:00:00

abstract：:A new case of acute renal failure after rifampicin is presented, together with a review of the 36 similar cases published up to date in the literature. Evidence is provided that irregularities in drug intake, either as true intermittent treatment or as discontinuation of continuous therapy, play an important role in t...

journal_title：Nephron

authors： Nessi R,Bonoldi GL,Redaelli B,di Filippo G

更新日期：1976-01-01 00:00:00

abstract：:Mean renal blood flow (MRBF), cortical blood flow (CBF), glomerular filtration rate (GFR), heart rate, arterial blood pressure, Na+ and K+ excretion were determined before and 10 min after intrarenal administration of dihydroergocristine (0.017 mg/kg b.w.) in 13 patients suffering from liver cirrhosis. Cardiac output ...

journal_title：Nephron

authors： Gatta A,Merkel C,Grassetto M,Milani L,Zuin R,Ruol A

更新日期：1982-01-01 00:00:00

abstract：:Primary hyperoxaluria type 1 (PH1) is caused by deficiency of peroxisomal alanine-glyoxylate aminotransferase which is in humans exclusively expressed in liver cells. The disease is inherited as an autosomal recessive trait, and initial symptoms usually occur in early childhood. Up to the age of 25 years, 90% of the p...

journal_title：Nephron

authors： David-Walek T,Niederstadt C,Rob PM,Fricke L,Latta K,Steinhoff J,Stange EF

更新日期：2001-01-01 00:00:00

abstract：:Methylguanidine (MG), guanidinosuccinic acid (GSA) and creatinine (Cr), which accumulate in the body in parallel with the progress of renal failure after adenine administration, were given separately to rats in order to compare their toxicities. Food containing adenine was given to rats for 24 days to induce renal fai...

journal_title：Nephron

authors： Yokozawa T,Mo ZL,Oura H

更新日期：1989-01-01 00:00:00

abstract：:A 2-year prospective study was done in 45 patients to see whether the FENa test, done at first nephrology consultation visit for acute renal failure, was useful in prognosticating whether patients would recover renal function spontaneously or need dialysis. Of 26 patients who recovered renal function spontaneously, 8 ...

journal_title：Nephron

authors： Pru C,Kjellstrand CM

更新日期：1984-01-01 00:00:00

abstract：:In 42 untreated patients at various stages of chronic renal failure, plasma level of parathyroid hormone was directly proportional to the degree of renal failure and inversely proportional to the serum calcium level. Plasma parathyroid hormone levels were frequently elevated in 21 patients undergoing regular dialysis ...

journal_title：Nephron

authors： Fuss M,De Backer M,Brauman J,Nijs-Dewolf N,Manderlier T,Brauman H,Corvilain J

更新日期：1976-01-01 00:00:00

abstract：:As with many other amino acids the transport of cystine across the tubular epithelium is coupled to a parallel transport of sodium. We have studied the effect of a sodium-restricted diet on the urinary excretion of cystine in 13 patients with cystinuria, 7 of whom were treated with the SH compound tiopronin (2-mercapt...

journal_title：Nephron

authors： Lindell A,Denneberg T,Edholm E,Jeppsson JO

更新日期：1995-01-01 00:00:00

abstract：:Rat sera, 10-30 h after unilateral nephrectomy (UNI), enhance 3H-thymidine ("3H-Tdr) incorporation into DNA of incubating renal tissue from control rats. Stimulation is even greater when extracts from remaining growing kidneys 20 h after UNI are combined with sera from rats after UNI. UNI extracts, i.e., extracts from...

journal_title：Nephron

authors： Castillo O,Robertson D,Goldin H,Preuss HG

更新日期：1980-01-01 00:00:00

abstract：:The recent experience of six large trials of antihypertensive therapy has not clearly demonstrated any beneficial effect on the prevention of coronary heart disease (CHD). The data from the HDFP study have been analyzed by three cholesterol strata at baseline. The higher the baseline cholesterol levels, the greater th...

journal_title：Nephron

authors： Schneider KA,Heyden S,Ford C

更新日期：1987-01-01 00:00:00

abstract：:Hematuria and proteinuria in rheumatoid arthritis (RA) are commonly associated with drug therapy but occur independently of drugs, amyloid or urologic disorders. The latter occurrences suggest a primary renal lesion associated with RA. Review of reported renal biopsies identifies mesangial glomerulopathy as a common f...

journal_title：Nephron

authors： Pollet S,Depner T,Moore P,Olander H,Robbins D

更新日期：1989-01-01 00:00:00

abstract：:Inflammation is broadly recognized as an important factor in the pathogenesis of acute kidney injury (AKI), but pharmacological approaches to alleviate inflammation in AKI have been without success in clinical trials. Neuromodulation by nonpharmacological methods is emerging as a novel therapeutic strategy to treat in...

journal_title：Nephron

authors： Tanaka S,Inoue T,Hossack JA,Okusa MD

更新日期：2017-01-01 00:00:00