Tetraspanin CD151 mediates papillomavirus type 16 endocytosis.

abstract：:The segment of simian virus 40 (SV40) genome which is recognized as the BC domain encodes for the COOH-terminal end of the SV40 major capsid protein VP1. Mutations in this domain lead to the synthesis of a thermosensitive VP1 which fails to assemble mature SV40 at the nonpermissive temperature. We determined the DNA s...

journal_title：Journal of virology

authors： Ng SC,Behm M,Bina M

更新日期：1985-05-01 00:00:00

abstract：:Epstein-Barr virus (EBV) efficiently drives proliferation of human primary B cells in vitro, a process relevant for human diseases such as infectious mononucleosis and posttransplant lymphoproliferative disease. Human B-cell proliferation is also driven by ligands of Toll-like receptors (TLRs), notably viral or bacter...

journal_title：Journal of virology

authors： Iskra S,Kalla M,Delecluse HJ,Hammerschmidt W,Moosmann A

更新日期：2010-04-01 00:00:00

abstract：:A deletion mutant of severe acute respiratory syndrome coronavirus (SARS-CoV) has been engineered by deleting the structural E gene in an infectious cDNA clone that was constructed as a bacterial artificial chromosome (BAC). The recombinant virus lacking the E gene (rSARS-CoV-DeltaE) was rescued in Vero E6 cells. The ...

journal_title：Journal of virology

authors： DeDiego ML,Alvarez E,Almazán F,Rejas MT,Lamirande E,Roberts A,Shieh WJ,Zaki SR,Subbarao K,Enjuanes L

更新日期：2007-02-01 00:00:00

abstract：:The aryl hydrocarbon receptor (AhR) is a cytoplasmic receptor/transcription factor that modulates several cellular and immunological processes following activation by pathogen-associated stimuli, though its role during virus infection is largely unknown. Here, we show that AhR is activated in cells infected with mouse...

journal_title：Journal of virology

authors： Grunewald ME,Shaban MG,Mackin SR,Fehr AR,Perlman S

更新日期：2020-01-17 00:00:00

abstract：:In view of the concern over potential infection hazards in the use of porcine tissues and organs for xenotransplantation to humans, we investigated the diversity of porcine endogenous retrovirus (PERV) genomes in the DNA of domestic pigs and related species. In addition to the three known envelope subgroups of infecti...

journal_title：Journal of virology

authors： Patience C,Switzer WM,Takeuchi Y,Griffiths DJ,Goward ME,Heneine W,Stoye JP,Weiss RA

更新日期：2001-03-01 00:00:00

abstract：:Hemorrhage is a common clinical manifestation in dengue patients. However, the pathogenic mechanism of dengue virus (DV)-induced hemorrhage awaits clarification. We established a mouse model of DV hemorrhage using immunocompetent C57BL/6 mice by injecting DV serotype 2 strain 16681 intradermally. While inoculation of ...

journal_title：Journal of virology

authors： Chen HC,Hofman FM,Kung JT,Lin YD,Wu-Hsieh BA

更新日期：2007-06-01 00:00:00

abstract：:The role of the Autographa californica multiple nucleopolyhedrovirus (AcMNPV) immediate-early protein IE0 in the baculoviral infection is not clear. In this study, we constructed the recombinant virus vAcDeltaie0 null for ie0 expression by targeted mutagenesis replacing exon0 with the cat gene. We found that vAcDeltai...

journal_title：Journal of virology

authors： Lu L,Rivkin H,Chejanovsky N

更新日期：2005-08-01 00:00:00

abstract：:Vaccinia virus genes are expressed in a sequential fashion, suggesting a role for negative as well as positive regulatory mechanisms. A potential down regulator of gene expression was mapped by transfection assays to vaccinia virus open reading frame D10, which encodes a protein with no previously known function. Inhi...

journal_title：Journal of virology

authors： Shors T,Keck JG,Moss B

更新日期：1999-01-01 00:00:00

abstract：:Human cytomegalovirus (HCMV) major immediate-early protein IE1 is an abundant 72-kDa nuclear phosphoprotein that is thought to play an important role in efficient triggering of the lytic cycle, especially at low multiplicity of infection. The best-known properties of IE1 at present are its transient targeting to punct...

journal_title：Journal of virology

authors： Xu Y,Ahn JH,Cheng M,apRhys CM,Chiou CJ,Zong J,Matunis MJ,Hayward GS

更新日期：2001-11-01 00:00:00

abstract：:Mouse neuroblastoma cells containing intracisternal type A particles were treated with iododeoxyuridine and dexamethasone to induce the release of type C oncornavirus particles. For 5 days after treatment, antigenic markers and DNA polymerase activities specific to particles of each of the two types were assayed in th...

journal_title：Journal of virology

authors： Kuff EL,Lueders KK,Orenstein JM,Wilson SH

更新日期：1976-08-01 00:00:00

abstract：:The human immunodeficiency virus Tat protein is essential for virus replication and is a candidate vaccine antigen. Macaques immunized with Tat or chemically modified Tat toxoid having the same clade B sequence developed strong antibody responses. We compared these antisera for their abilities to recognize diverse Tat...

journal_title：Journal of virology

authors： Tikhonov I,Ruckwardt TJ,Hatfield GS,Pauza CD

更新日期：2003-03-01 00:00:00

abstract：:Dengue virus (DENV) is a major global pathogen that causes significant morbidity and mortality in tropical and subtropical areas worldwide. An improved understanding of the regions within the DENV genome and its encoded proteins that are required for the virus replication cycle will expedite the development of urgentl...

journal_title：Journal of virology

authors： Eyre NS,Johnson SM,Eltahla AA,Aloi M,Aloia AL,McDevitt CA,Bull RA,Beard MR

更新日期：2017-11-14 00:00:00

abstract：:The induction of a unique macrophage procoagulant molecule by murine hepatitis virus strain 3 correlates with the severity of viral hepatitis. The role of tyrosine phosphorylation in the signalling pathway leading to procoagulant expression was studied. Murine hepatitis virus strain 3 initiated a rapid increase in pho...

journal_title：Journal of virology

authors： Dackiw AP,Zakrzewski K,Nathens AB,Cheung PY,Fingerote R,Levy GA,Rotstein OD

更新日期：1995-09-01 00:00:00

abstract：:Satellite RNAs are the smallest infectious agents whose replication is thought to be completely dependent on their helper virus (HV). Here we report that, when expressed autonomously in the absence of HV, a variant of satellite RNA (satRNA) associated with Cucumber mosaic virus strain Q (Q-satRNA) has a propensity to ...

journal_title：Journal of virology

authors： Choi SH,Seo JK,Kwon SJ,Rao AL

更新日期：2012-05-01 00:00:00

abstract：:Herpesviruses establish latency in suitable host cells after primary infection and persist in their host organisms for life. Most of the viral genes are silenced during latency, also enabling the virus to escape from an immune response. This study addresses the control of viral gene silencing by epigenetic mechanisms,...

journal_title：Journal of virology

authors： Alberter B,Vogel B,Lengenfelder D,Full F,Ensser A

更新日期：2011-06-01 00:00:00

abstract：UNLABELLED:The expression of the antiviral host cell factor tetherin is induced by interferon and can inhibit the release of enveloped viruses from infected cells. The Vpu protein of HIV-1 antagonizes the antiviral activity of tetherin, and tetherin antagonists with Vpu-like activity have been identified in other virus...

journal_title：Journal of virology

authors： Gnirß K,Zmora P,Blazejewska P,Winkler M,Lins A,Nehlmeier I,Gärtner S,Moldenhauer AS,Hofmann-Winkler H,Wolff T,Schindler M,Pöhlmann S

更新日期：2015-09-01 00:00:00

abstract：:Herpes simplex virus type 1 (HSV-1) is a large (150-kb) double-stranded DNA virus that forms latent infections in neuronal cells of the human peripheral nervous system. Previous work determined that the HSV-1 genome is found in an ordered nucleosomal structure during latent infection. However, during lytic infection, ...

journal_title：Journal of virology

authors： Kent JR,Zeng PY,Atanasiu D,Gardner J,Fraser NW,Berger SL

更新日期：2004-09-01 00:00:00

abstract：:Murine gammaherpesvirus 68 (gammaHV68; also known as MHV-68) can establish a latent infection in both inbred and outbred strains of mice and, as such, provides a tractable small-animal model to address mechanisms and cell types involved in the establishment and maintenance of chronic gammaherpesvirus infection. Latenc...

journal_title：Journal of virology

authors： Willer DO,Speck SH

更新日期：2003-08-01 00:00:00

abstract：:To evaluate host range differences between two different strains of feline leukemia virus subgroup B (FeLV-B), we compared the binding and infectivity patterns of retrovirus vectors bearing either FeLV-B-90Z or FeLV-B-GA envelopes. We report here that the ability of these envelopes to utilize different Pit1 orthologs ...

journal_title：Journal of virology

authors： Faix PH,Feldman SA,Overbaugh J,Eiden MV

更新日期：2002-12-01 00:00:00

abstract：:The VP6 protein of bluetongue virus possesses a number of activities, including nucleoside triphosphatase, RNA binding, and helicase activity (N. Stauber, J. Martinez-Costas, G. Sutton, K. Monastyrskaya, and P. Roy, J. Virol. 71:7220-7226, 1997). Although the enzymatic functions of the protein have been documented, a ...

journal_title：Journal of virology

authors： Kar AK,Roy P

更新日期：2003-11-01 00:00:00

abstract：:The degree of genetic variability in the hypervariable region 1 of hepatitis C virus (HCV) was analyzed by cloning and sequencing HCV genomes obtained in paired samples of serum, liver tissue, and peripheral blood mononuclear cells (PBMC) from four chronic hepatitis C patients. Genetic variability in serum was higher ...

journal_title：Journal of virology

authors： Navas S,Martín J,Quiroga JA,Castillo I,Carreño V

更新日期：1998-02-01 00:00:00

abstract：:Many viruses express inhibitors of programmed cell death (apoptosis), thereby countering host defenses that would otherwise rapidly clear infected cells. To counter this, viruses such as adenoviruses and herpesviruses express recognizable homologs of the mammalian prosurvival protein Bcl-2. In contrast, the majority o...

journal_title：Journal of virology

authors： Okamoto T,Campbell S,Mehta N,Thibault J,Colman PM,Barry M,Huang DC,Kvansakul M

更新日期：2012-11-01 00:00:00

abstract：UNLABELLED:Many coxsackievirus B (CVB) isolates bind to human decay-accelerating factor (DAF) as well as to the coxsackievirus and adenovirus receptor (CAR). However, the virus does not interact with murine DAF. To understand why CVB3 binds specifically to human DAF, we constructed a series of chimeric molecules in whi...

journal_title：Journal of virology

authors： Pan J,Zhang L,Organtini LJ,Hafenstein S,Bergelson JM

更新日期：2015-01-15 00:00:00

abstract：:Little is known about the biological significance of human adenovirus type 5 (Ad5) E1A in vivo. However, Ad5 E1A is well defined in vitro and can be detected frequently in the lungs of patients with pulmonary disease. Transgenic expression of the Ad5 E1A gene targeted to the mouse lung reveals distinct biological effe...

journal_title：Journal of virology

authors： Yang Y,McKerlie C,Borenstein SH,Lu Z,Schito M,Chamberlain JW,Buchwald M

更新日期：2002-09-01 00:00:00

abstract：UNLABELLED:Next-generation sequence analysis of virus-like particles (VLPs) produced during agroinfiltration of cucumber necrosis virus (CNV) coat protein (CP) and of authentic CNV virions was conducted to assess if host RNAs can be encapsidated by CNV CP. VLPs containing host RNAs were found to be produced during agro...

journal_title：Journal of virology

authors： Ghoshal K,Theilmann J,Reade R,Maghodia A,Rochon D

更新日期：2015-11-01 00:00:00

abstract：:Recent evidence supports a role for vitamin K-dependent coagulation zymogens in adenovirus serotype 5 (Ad5, subgroup C) infection of hepatocytes. Here, we assessed the effect of virus-zymogen interaction on cellular transduction using a panel of fiber (f)-pseudotyped viruses derived from subgroup D (f47, f33, f24, f45...

journal_title：Journal of virology

authors： Parker AL,McVey JH,Doctor JH,Lopez-Franco O,Waddington SN,Havenga MJ,Nicklin SA,Baker AH

更新日期：2007-04-01 00:00:00

abstract：:We demonstrate that the S4 genome segment of baboon reovirus (BRV) contains two sequential partially overlapping open reading frames (ORFs), both of which are functional in vitro and in virus-infected cells. The 15-kDa gene product (p15) of the 5"-proximal ORF induces efficient cell-cell fusion when expressed by itsel...

journal_title：Journal of virology

authors： Dawe S,Duncan R

更新日期：2002-03-01 00:00:00

abstract：:Replication of flock house virus (FHV) RNA1 and production of subgenomic RNA3 in the yeast Saccharomyces cerevisiae provide a useful tool for the dissection of FHV molecular biology and host-encoded functions involved in RNA replication. The replication template activity of RNA1 can be separated from its coding potent...

journal_title：Journal of virology

authors： Lindenbach BD,Sgro JY,Ahlquist P

更新日期：2002-04-01 00:00:00

abstract：:Infection of microglia and other cells of the macrophage/monocyte lineage in the central nervous system (CNS) by human immunodeficiency virus type I (HIV-1) underlies the development of giant cell encephalitis (GCE). It is currently unknown whether GCE depends on the emergence of virus populations specifically adapted...

journal_title：Journal of virology

authors： Wang TH,Donaldson YK,Brettle RP,Bell JE,Simmonds P

更新日期：2001-12-01 00:00:00

abstract：:Hypervariable region 5 (HVR5) is a hydrophilic, serotypically nonconserved loop of the hexon monomer which extrudes from the adenovirus (Ad) capsid. We have replaced the HVR5 sequence of Ad5 with that of heterologous peptides and studied their effects on virus viability and peptide accessibility. A poliovirus model ep...

journal_title：Journal of virology

authors： Vigne E,Mahfouz I,Dedieu JF,Brie A,Perricaudet M,Yeh P

更新日期：1999-06-01 00:00:00