Pneumocystis jiroveci pneumonia and colonization in patients with advanced lung cancer.

abstract：:Gastric cancer (GC) is the second leading cause of cancer-related mortality worldwide. The usual treatment of GC consists of surgery with additional adjuvant chemotherapy. In the present study, the feasibility and safety of adjuvant S-1 plus oxaliplatin (SOX) chemotherapy for patients with GC and the optimal dosage of...

journal_title：Oncology letters

authors： Yang L,Yang Y,Qin Q,Zhou A,Zhao J,Wang J,Shu C,Yuan X,Hu S

更新日期：2015-03-01 00:00:00

abstract：:Cell adhesion molecule (CADM) genes encode immunoglobulin superfamily molecules, which are involved in cell-cell adhesion in a number of human epithelia. Through the maintenance of epithelia, CADM genes protect against malignant conversion and metastasis. Whilst numerous in vitro studies have investigated the molecula...

journal_title：Oncology letters

authors： Saito M,Goto A,Abe N,Saito K,Maeda D,Ohtake T,Murakami Y,Takenoshita S

更新日期：2018-02-01 00:00:00

abstract：:Individuals >65 years old account for a large proportion of cancer patients, and usually have poor prognoses due to relative weaker physiological function and lower drug tolerance. To characterize the efficacy and safety of dendritic cell (DC)-activated cytokine-induced killer cell (CIK)-mediated treatment, and develo...

journal_title：Oncology letters

authors： Liu Y,Liu H,Liu H,He P,Li J,Liu X,Chen L,Wang M,Xi J,Wang H,Zhang H,Zhu Y,Zhu W,Ning J,Guo C,Sun C,Zhang M

更新日期：2016-12-01 00:00:00

abstract：:Serine/threonine kinase 39 (STK39) is associated with hypertension, autism, Parkinson's disease and various types of cancer in recent years. This study investigated STK39 expression and possible roles in osteosarcoma using qPCR and western blot analysis. Compared to normal bone tissues, the mRNA and protein expression...

journal_title：Oncology letters

authors： Huang T,Zhou Y,Cao Y,Tao J,Zhou ZH,Hang DH

更新日期：2017-10-01 00:00:00

abstract：:The present study aimed to investigate the association between insulin-like growth factor-1 (IGF-1) and matrix metalloproteinase-11 (MMP-11) expression in gastric cancer (GC) and the underlying mechanisms in SGC-7901 cells. Reverse transcription-quantitative polymerase chain reaction analysis revealed that the express...

journal_title：Oncology letters

authors： Su C,Wang W,Wang C

更新日期：2018-05-01 00:00:00

abstract：:The Mantle Cell Lymphoma International Prognostic Index (MIPI) combines four factors to differentiate low-, intermediate- and high-risk prognostic groups in advanced mantle cell lymphoma using data from patients treated in clinical trials. To evaluate its use in routine practice, we applied the simplified index retros...

journal_title：Oncology letters

authors： Lim SY,Horsman JM,Hancock BW

更新日期：2010-01-01 00:00:00

abstract：:The present study analyzed polymorphisms of the 5' flanking region (from nt -840 to +151) of the haptoglobin gene in 120 patients with advanced non-small cell lung cancer (NSCLC) receiving personalized peptide vaccinations. In the region, six single nucleotide polymorphisms (SNPs) were confirmed, of which two, rs5472 ...

journal_title：Oncology letters

authors： Waki K,Yamada T,Yoshiyama K,Terazaki Y,Sakamoto S,Sugawara S,Takamori S,Itoh K,Yamada A

更新日期：2017-02-01 00:00:00

abstract：:The S100 protein family is widely involved in the pathological process of various types of cancer. However, the prognostic value of the S100 protein family member S100A12 in hepatocellular carcinoma (HCC) remains unknown. A total of 139 patients undergoing curative surgical resection for HCC from December 2005 to June...

journal_title：Oncology letters

authors： Cai H,Ye BG,Ao JY,Zhu XD,Zhang YY,Chai ZT,Wang CH,Sun HC

更新日期：2018-10-01 00:00:00

abstract：:Tuberous sclerosis complex (TSC) is an autosomal dominant disease involving multiple organs, but there are a limited number of reports on family TSC. In the present report, a case of a 52-year-old female with a familial genetic TSC, associated with bilateral giant renal angiomyolipoma, was described. The mother, secon...

journal_title：Oncology letters

authors： Wang L,Ni D,Zhong L,Wang J

更新日期：2017-12-01 00:00:00

abstract：:Overexpression of adenosine triphosphate-binding cassette (ABC) transport protein is emerging as a critical contributor to anticancer drug resistance. The eukaryotic translation initiation factor (eIF) 4F complex, the key modulator of mRNA translation, is regulated by the phosphoinositide 3-kinase-AKT-mammalian target...

journal_title：Oncology letters

authors： Pan X,Yang X,Zang J,Zhang S,Huang N,Guan X,Zhang J,Wang Z,Li X,Lei X

更新日期：2017-06-01 00:00:00

abstract：:Melanoma is the most severe type of skin cancer and its incidence has increased in the last decades. In the United States, it is the 6th most common cancer in both men and women. Prognosis for patients with melanoma depends on the stage of the disease at the time of diagnosis and it can be influenced by the immunologi...

journal_title：Oncology letters

authors： Antohe M,Nedelcu RI,Nichita L,Popp CG,Cioplea M,Brinzea A,Hodorogea A,Calinescu A,Balaban M,Ion DA,Diaconu C,Bleotu C,Pirici D,Zurac SA,Turcu G

更新日期：2019-05-01 00:00:00

abstract：:The aim of the present study was to explore the therapeutic effect of 20 kHz ultrasound (US) and microbubbles (MBs) on rabbit VX2 liver tumors by spiral computed tomography (CT) scanning. A total of 16 New Zealand rabbits with hepatic VX2 tumors were divided into four groups: Control, MB, low-frequency US and US + MB....

journal_title：Oncology letters

authors： Shen ZY,Liu C,Wu MF,Shi HF,Zhou YF,Zhuang W,Xia GL

更新日期：2017-09-01 00:00:00

abstract：:Ovarian endometrioid borderline tumors (EBTs) are extremely rare, and are thought to be precursors of endometrioid carcinoma, beginning as adenofibroma or endometriosis and progressing in a slow, stepwise manner. In endometrioid carcinomas, a high frequency of activating mutations in phosphatase and tensin homolog (PT...

journal_title：Oncology letters

authors： Nakamura K,Nakayama K,Ishikawa M,Minamoto T,Ishibashi T,Sato E,Sanuki K,Yamashita H,Ono R,Iida K,Sultana R,Hossain MM,Ishikawa N,Kyo S

更新日期：2018-07-01 00:00:00

abstract：:Recently, a number of microRNAs (miRNAs) have been reported to play different roles in human cancers, including colorectal cancer (CRC). However, the specific role of miR-758 has not been clarified in CRC. Therefore, the aim of the present study was to explore the role of miR-758 in CRC. RT-qPCR and western blot analy...

journal_title：Oncology letters

authors： Zhang X,Xu J,Zhang H,Sun J,Li N,Huang X

更新日期：2020-06-01 00:00:00

abstract：:For individualized bevacizumab-based therapy, non-invasive biomarkers are necessary. This study assessed the predictive value of plasma vascular endothelial growth factor (VEGF)-A, soluble VEGF receptor (sVEGFR)-1 and sVEGFR-2 levels as biomarkers for clinical response and survival in advanced colorectal cancer (CRC) ...

journal_title：Oncology letters

authors： Aoyagi Y,Iinuma H,Horiuchi A,Shimada R,Watanabe T

更新日期：2010-03-01 00:00:00

abstract：:The majority of giant cell tumors (GCTs) occur in the ends of the long bones. The presence of more than one GCT in the axial skeleton is rare. A GCT is capable of remaining clinically latent following treatment and becoming active a number of years later. We report an extremely rare case of GCT occurring in the axial ...

journal_title：Oncology letters

authors： Park YS,Lee JK,Baek SW,Park CK

更新日期：2011-11-01 00:00:00

abstract：:The recognition of the biological relevance of long non-coding RNA (lncRNA) molecules has only recently been recognized as one of the most significant advances in contemporary molecular biology. A growing body of evidence indicates that lncRNAs act not only as the intermediary between DNA and protein but also as signi...

journal_title：Oncology letters

authors： Yu X,Li Z

更新日期：2015-10-01 00:00:00

abstract：:Pulmonary tumor thrombotic microangiopathy (PTTM) is an uncommon cancer-related complication characterized by intimal proliferation in pulmonary small arteries and arterioles with or without tumor emboli. In the majority of cases, the causative lesion is gastric poorly differentiated adenocarcinoma. In the present stu...

journal_title：Oncology letters

authors： Hotta M,Ishida M,Kojima F,Iwai Y,Okabe H

更新日期：2011-05-01 00:00:00

abstract：:Point mutation of the BRAF gene is a genetic event that occurs in a subset of lung adenocarcinoma cases. For example, BRAF V600E is a driver mutation that can be effectively targeted using selective BRAF and/or MEK inhibitors. The present study hypothesized that an increase in BRAF copy number may be correlated with c...

journal_title：Oncology letters

authors： Sasaki H,Maekawa M,Tatematsu T,Okuda K,Moriyama S,Yano M,Fujii Y

更新日期：2015-02-01 00:00:00

abstract：:Recommendations concerning the intake of vitamin D and/or sunlight exposure in the handling of patients with vitamin D deficiency remain a matter of debate. The present study of the German network of dermato-oncologists (Onkoderm e.V.) refers to an inquiry conducted among general practitioners on this and related issu...

journal_title：Oncology letters

authors： Reinhold U,Dirschka T,Hartgens K,Kirchesch H,Ostendorf R,Petering H,Prieur H,Krähn-Senftleben G,Malaisse WJ

更新日期：2012-12-01 00:00:00

abstract：:Malignant transformation of an epidermoid cyst is rare. The current report presents a case of a 55-year-old female patient with squamous cell carcinoma arising from a benign epidermoid cyst in the left temporal region and prepontine area. She had undergone subtotal resection of an epidermoid cyst 7 months previously. ...

journal_title：Oncology letters

authors： Ding S,Jin Y,Jiang J

更新日期：2016-05-01 00:00:00

abstract：:Photodynamic therapy (PDT) is a treatment modality that has clinical applications in both non-neoplastic and neoplastic diseases. PDT involves a light-sensitive compound (photosensitizer), light and molecular oxygen. This procedure may lead to several different cellular responses, including cell death. Alterations in ...

journal_title：Oncology letters

authors： Pacheco-Soares C,Maftou-Costa M,DA Cunha Menezes Costa CG,DE Siqueira Silva AC,Moraes KC

更新日期：2014-08-01 00:00:00

abstract：:The present study aimed to identify microRNA (miRNA) expression profiles associated with brain metastases of colorectal cancers. We conducted miRNA expression profiling of 3 primary colorectal cancers and 3 brain-metastatic carcinomas using Agilent Human miRNA Microarrays. Quantitative real-time reverse transcription-...

journal_title：Oncology letters

authors： Li Z,Gu X,Fang Y,Xiang J,Chen Z

更新日期：2012-02-01 00:00:00

abstract：:Previous studies have shown that the activation of the β2 adrenergic receptor (ADRB2) can stimulate several signaling pathways that promote tumor growth and metastasis. β-adrenergic antagonism may have a beneficial role in cancer treatment; however, little is known about the effect of ADRB2 inhibition on the growth of...

journal_title：Oncology letters

authors： Dang D,Zhang J,Yang J

更新日期：2018-08-01 00:00:00

abstract：:Observational and experimental studies have produced inconsistent evidence about the association of serum levels of B-type natriuretic peptide (BNP) with anthracycline-induced cardiotoxicity (AIC). Therefore, the current meta-analysis examined the association between serum BNP levels and AIC by using data from high qu...

journal_title：Oncology letters

authors： Wang YD,Chen SX,Ren LQ

更新日期：2016-05-01 00:00:00

abstract：:Ductal adenocarcinoma of the prostate (DAP) is a rare variant of prostate cancer, and has poorly-identified clinical characteristics. Few cases have been previously reported in Chinese males and DAP is more commonly reported in Caucasian males over 70-years of age. In the present study, a 55-year-old Chinese male pati...

journal_title：Oncology letters

authors： Ji C,Zhou M,Gan W,Zheng J,Yan X,Guo H

更新日期：2016-02-01 00:00:00

abstract：:The aim of the present study was to investigate the association between methylation of cyclin-dependent kinase inhibitor 2B (CDKN2B) CpG islands and telomerase activity in children with acute lymphoblastic leukemia (ALL). A total of 72 children with ALL and 12 children with immune thrombocytopenia (ITP) were subjected...

journal_title：Oncology letters

authors： Hu Q,Chen X,Liu S,Wen R,Yuan X,Xu D,Liu G,Wen F

更新日期：2017-04-01 00:00:00

abstract：:Overexpression of apoptosis-stimulating of p53 protein 2 (ASPP2) can induce apoptotic cell death in hepatoma cells, which contributes to a killing effect of ASPP2 on treating hepatocellular carcinoma (HCC). In the present study, ASPP2 overexpression failed to induce apoptotic cell death in the HCC Huh7.5 cell line, bu...

journal_title：Oncology letters

authors： Liu D,Li R,Guo X,Pang L,Zang Y,Liu K,Chen D

更新日期：2018-06-01 00:00:00

abstract：:Hepatitis B virus × protein (HBx) serves an important role in the pathogenesis of the hepatitis B virus infection. Previous studies have reported that the interaction between HBx and hepatocyte mitochondria is an important factor leading to liver cell injury and apoptosis, ultimately inducing the formation of liver ca...

journal_title：Oncology letters

authors： Ling LR,Zheng DH,Zhang ZY,Xie WH,Huang YH,Chen ZX,Wang XZ,Li D

更新日期：2020-04-01 00:00:00

abstract：:Clear cell myoepithelial carcinoma is a very rare disease which develops primarily in the parotid gland. To date, only 17 cases of clear cell myoepithelial carcinoma have been reported worldwide. Among them, only three cases developed in the minor salivary gland in the oral cavity. No cases developed in the base of th...

journal_title：Oncology letters

authors： Park JH,Choi JY,Hong R,DO NY

更新日期：2012-12-01 00:00:00