Extremely low-frequency magnetic field induces manganese accumulation in brain, kidney and liver of rats.

Abstract:

:The aim of the present study was to determine the effects of extremely low-frequency magnetic field (ELF-MF) on accumulation of manganese (Mn) in the kidney, liver and brain of rats. A total of 40 rats were randomly divided into eight groups. Four control groups received 0, 3.75, 15 and 60 mg Mn per kg body weight orally every 2 days for 45 days, respectively. The remaining four groups received same concentrations of Mn and were also exposed to ELF-MF (1.5 mT; 50 Hz) for 4 h for 5 days a week during 45 days. Following the last exposure, kidney, liver and brain were taken from all rats and they were analyzed for Mn accumulation levels using an inductively coupled plasma-optical emission spectrometer. In result of the current study, we observed that Mn levels in brain, kidney and liver were higher in Mn groups than in control groups. Mn levels in brain, kidney and liver were also higher in Mn plus ELF-MF groups than in Mn groups. In conclusion, result of the current study showed that the ELF-MF induced manganese accumulation in kidney, liver and brain of rats.

journal_name

Toxicol Ind Health

authors

Çelik MS,Güven K,Akpolat V,Akdağ MZ,Nazıroğlu M,Gül-Güven R,Çelik MY,Erdoğan S

doi

10.1177/0748233713480204

subject

Has Abstract

pub_date

2015-06-01 00:00:00

pages

576-80

issue

6

eissn

0748-2337

issn

1477-0393

pii

0748233713480204

journal_volume

31

pub_type

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