Genotoxicity studies of a desealant solvent mixture, SR-51.

abstract：:People live in the mountains distributed across the world and are exposed to reduced inspired oxygen and lower barometric pressure along with other factors that lead to high-altitude diseases. The present study was conducted to examine what extent of marketed medicines used in the management of high-altitude sickness ...

journal_title：Toxicology and industrial health

authors： Ghosh M,Biswas D,Mukherjee A

更新日期：2010-08-01 00:00:00

abstract：:The hypolipidemic effect of 10% fruit fibers in rats fed with high-fat diet (HFD) was evaluated. This study was conducted on a total of 50 male Albino rats divided into 10 equal groups fed with different types of dietary fruits. The feeding period lasted for 24 weeks. Fasting blood samples were collected and sera sepa...

journal_title：Toxicology and industrial health

authors： Esmael OA,Sonbul SN,Kumosani TA,Moselhy SS

更新日期：2015-03-01 00:00:00

abstract：:Cyclophosphamide (CP) is an alkylating agent that has been considered effective for cancer treatment. Lycopene, the pigment in tomato fruits, has beneficial effect in the treatment of some diseases. The goal of this study is to evaluate the protective effect of lycopene alone or combined with melatonin (Mel) in inhibi...

journal_title：Toxicology and industrial health

authors： Al-Malki AL

更新日期：2014-07-01 00:00:00

abstract：:Recently, we have detailed a DNA alkaline unwinding assay (DAUA) that can be used to rapidly measure chemically induced strand breaks in mammalian cells (Daniel et al., 1985). In this paper we present further development of this assay, including: (1) studies on the relationship between DNA adducts and DNA strand break...

journal_title：Toxicology and industrial health

authors： Daniel FB,Chang LW,Schenck KM,DeAngelo AB,Skelly MF

更新日期：1989-10-01 00:00:00

abstract：:Peracetic acid (PAA) is a corrosive chemical with a pungent odor, which is extensively used in occupational settings and causes various health hazards in exposed workers. Currently, there is no US government agency recommended method that could be applied universally for the sampling and analysis of PAA. Legacy method...

journal_title：Toxicology and industrial health

authors： Nordling J,Kinsky OR,Osorio M,Pechacek N

更新日期：2017-12-01 00:00:00

abstract：:Yoghurt is a popular dairy product in Iran because of its beneficial influence on human health and nutritional value. Aflatoxin M1 (AFM1) is the metabolite of potential carcinogen aflatoxin B1, which can contaminate milk through the feed and is not eliminated by common processing heat treatment. An analytical method u...

journal_title：Toxicology and industrial health

authors： Tabari M,Karim G,Ghavami M,Chamani M

更新日期：2011-08-01 00:00:00

abstract：:The bromoalkane, 1-bromopropane (1-BP), may damage the reproductive system though oxidative stress, while the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2) plays an important role in regulating intracellular antioxidant levels against oxidative stress. This study explored the role of oxidativ...

journal_title：Toxicology and industrial health

authors： Yang G,Xiang Y,Zhou W,Zhong X,Zhang Y,Lin D,Huang X

更新日期：2020-12-11 00:00:00

abstract：:The US Air Force has implemented the widespread use of JP-8 jet fuel in its operations, although a thorough understanding of its potential effects upon exposed personnel is unclear. Previous work has reported that JP-8 exposure is immunosuppressive. In the present study, the effects of in-utero JP-8 jet fuel exposure ...

journal_title：Toxicology and industrial health

authors： Harris DT,Sakiestewa D,He X,Titone D,Witten M

更新日期：2007-10-01 00:00:00

abstract：:Cutting fluids can become contaminated with metals (e.g., nickel, Ni) and nitrosamines (e.g., N-nitrosodiethanolamine, NDELA) and there is concern that these classes of contaminants can modulate dermal disposition and ultimately the toxicity of cutting fluid additives, such as irritant biocides (e.g., triazine). Bioci...

journal_title：Toxicology and industrial health

authors： Baynes RE,Brooks JD,Barlow BM,Riviere JE

更新日期：2005-10-01 00:00:00

abstract：:The aim of this study was to investigate the effect of oral cadmium (Cd) intoxication on the antioxidant response and its relationship with essential bioelements like copper (Cu) and zinc (Zn). The experimental group was chronically exposed to Cd daily for 8 weeks via consumption of water containing 15 ppm cadmium chl...

journal_title：Toxicology and industrial health

authors： Erdem O,Yazihan N,Kocak MK,Sayal A,Akcil E

更新日期：2016-08-01 00:00:00

abstract：:Occupational exposure in a copper smelting industry may produce various adverse health effects including cancer. Despite a number of well-documented studies reporting an increased risk of cancer among copper smelter workers, the data on genotoxic effects in this industry are scarce. In view of the above, an assessment...

journal_title：Toxicology and industrial health

authors： De Olivera JV,Boufleur LA,Dos Santos CE,Dias JF,Squeff CH,Silva GR,Ianistcki M,Benvegnú VC,Da Silva J

更新日期：2012-10-01 00:00:00

abstract：:The aryl hydrocarbon receptor (AHR) is one of the principal xenobiotic, nuclear receptor that is responsible for the early events involved in the transcription of a complex set of genes comprising the CYP450 gene family. In the present computational study, homology modelling and molecular docking were carried out with...

journal_title：Toxicology and industrial health

authors： Panda R,Cleave AS,Suresh PK

更新日期：2014-09-01 00:00:00

abstract：:Molecular mechanisms in the pathogenesis of silicosis are not fully understood. Exposure to crystalline silica leads to the activation of signaling pathways controlling the production and secretion of inflammatory mediators. Inflammatory cytokines are noted as important candidate genes for fibrotic lung diseases. Cyto...

journal_title：Toxicology and industrial health

authors： Mohebbi I,Rad IA,Bagheri M

更新日期：2013-10-01 00:00:00

abstract：:Carbendazim is a broad spectrum carbamate fungicide used in the control of various fungal pathogens. Licorice (Glycyrrhiza glabra) is one of the widely used medicinal plants in oriental nations. The present work studied the effect of licorice aqueous extract on carbendazim-induced testicular toxicity in albino rats. A...

journal_title：Toxicology and industrial health

authors： Sakr SA,Shalaby SY

更新日期：2014-04-01 00:00:00

abstract：:Zinc oxide nanoparticles (ZnO NPs) are produced in high tonnage each year; they are widely used in consumer and industrial products, also now finding applications in bioimaging and drug delivery. In the present study, comparison between ZnO NPs (39 nm) and its bulk/micron form (particle size = 5 µm) on liver function ...

journal_title：Toxicology and industrial health

authors： Moatamed ER,Hussein AA,El-Desoky MM,Khayat ZE

更新日期：2019-10-01 00:00:00

abstract：:Silver nanoparticles (Ag NPs) are widely used in nanomedicine, pharmaceutical products, industry and other consumer products owing to their unique physiochemical properties with probable potential risk to human health and the ecosystems. The aim of this work was to investigate the in-life morphological effects, bioche...

journal_title：Toxicology and industrial health

authors： Al-Doaiss AA,Jarrar Q,Alshehri M,Jarrar B

更新日期：2020-08-01 00:00:00

abstract：:In summary, we have described our method of treating phosgene inhalation injury. We have presented two serious cases in detail which demonstrate that survival was associated with aggressive therapy. Several points should be mentioned. The pulmonary edema and resulting fluid and foam production can be so copious as to ...

journal_title：Toxicology and industrial health

authors： Regan RA

更新日期：1985-10-01 00:00:00

abstract：:The risk assessment process must encompass all available toxicological data and scientific evidence on the plausible toxicities of a chemical or chemical mixture. As an extension to the approaches used to conduct risk assessments on chemical mixtures, a preliminary scheme, analogous to the IARC classification of carci...

journal_title：Toxicology and industrial health

authors： Mumtaz MM,Durkin PR

更新日期：1992-11-01 00:00:00

abstract：:Two prospective, longitudinal studies-one in North Carolina and one in Michigan-have examined effects of prenatal polychlorinated biphenyl (PCB) exposure on behavioral and cognitive development in infants and children. The Michigan cohort was selected to overrepresent the offspring of women who had eaten relatively la...

journal_title：Toxicology and industrial health

authors： Jacobson JL,Jacobson SW

更新日期：1996-05-01 00:00:00

abstract：:In the present study, the single and combined neurotoxic effects of benzo[a]pyrene ([BaP] 0.0, 0.5, and 5.0 mg/kg body weight; intragastric administration) and lead acetate (0.0, 5.4, and 54.0 mg/L; by drinking water) were examined on KunMing mice. In the Morris water maze, results showed that BaP and lead induced syn...

journal_title：Toxicology and industrial health

authors： Youbin Q,Chengzhi C,Yan T,Xuejun J,Chongying Q,Bin P,Baijie T

更新日期：2013-06-01 00:00:00

abstract：:Arsenic is an ubiquitous and well-documented carcinogenic metalloid. The most common source of arsenic is drinking water. The mechanism of arsenic toxicity in a cell has historically been centered around its inhibitory effects on cellular respiration and mitochondrial injury. Ascorbic acid, a low molecular weight, wat...

journal_title：Toxicology and industrial health

authors： Singh S,Rana SV

更新日期：2010-06-01 00:00:00

abstract：:In allelopathy, one plant suppresses the growth and development of other plant/plants by negatively affecting a variety of physiological and biochemical reactions. We checked the effects of methanolic extracts (allelochemical extracts) of Phytolacca latbenia (Moq.) H. Walter on antioxidant enzyme activities such as pe...

journal_title：Toxicology and industrial health

authors： Ullah N,Haq IU,Safdar N,Mirza B

更新日期：2015-10-01 00:00:00

abstract：:Zinc oxide nanoparticles (ZnONP) are manufactured on a large scale and can be found in a variety of consumer products, such as sunscreens, lotions, paints and food additives. Few studies have been carried out on its genotoxic potential and related mechanisms in whole organisms. In the present study, the in vivo genoto...

journal_title：Toxicology and industrial health

authors： Carmona ER,Inostroza-Blancheteau C,Rubio L,Marcos R

更新日期：2016-12-01 00:00:00

abstract：:The morphological changes of ricin-induced apoptosis in a human cervical cancer cell line were studied. To shed light on the mechanism of action of ricin toxin (RT) at the cellular level, we examined cell growth, apoptosis, changes of mitochondrial membrane potential (MMP) and cytochrome C translocation in HeLa cells ...

journal_title：Toxicology and industrial health

authors： Liao P,Liu W,Li H,Gao H,Wang H,Li N,Xu N,Li J,Wan J,Liu L,Sun Y

更新日期：2012-06-01 00:00:00

abstract：:The reporting of physical symptoms is influenced to a large degree by psychological processes. Individuals are more likely to notice subtle sensations in environments lacking in stimulation than those demanding external attention. The beliefs or schemas that people hold dictate where and how they attend to their bodie...

journal_title：Toxicology and industrial health

authors： Pennebaker JW

更新日期：1994-07-01 00:00:00

abstract：:The purpose of this study was to characterize the ultrastructural changes in the muscles of 2- and 6-month-old rats that were injected with 6-mercaptopurine monohydrate (6-MP) at 2 mg base/kg sc daily from 2 to 22 days of age. The earliest, usually subsarcolemmal alterations, were disorganization of fibrils at the Z-b...

journal_title：Toxicology and industrial health

authors： Abraham AA,Veronesi B,Alleva FR,Balazs T

更新日期：1986-09-01 00:00:00

abstract：:Several classes of environmental contaminants have been claimed or suggested to possess endocrine-disrupting potency, which may result in reproductive problems and developmental disorders. In this paper the focus is on the multiple and interactive mechanisms of interference of persistent polyhalogenated aromatic hydro...

journal_title：Toxicology and industrial health

authors： Brouwer A,Morse DC,Lans MC,Schuur AG,Murk AJ,Klasson-Wehler E,Bergman A,Visser TJ

更新日期：1998-01-01 00:00:00

abstract：:The purpose of this study was to describe for asthmatic subjects the distribution of individual bronchial sensitivity to sulfur dioxide (SO2). Subjects were nonsmoking male asthmatics (n = 27) who were sensitive to inhaled methacholine. None of the subjects used corticosteroids or cromolyn sodium. Oral medications wer...

journal_title：Toxicology and industrial health

authors： Horstman D,Roger LJ,Kehrl H,Hazucha M

更新日期：1986-09-01 00:00:00

abstract：:We recently determined that the metabolism of a series of tumorigenic pyrrolizidine alkaloids resulted in the formation of a set of 6,7-dihydro-7-hydroxy-1-hydroxymethyl-5H-pyrrolizine (DHP)-derived DNA adducts. These DHP-derived DNA adducts have been proposed as potential biomarkers of pyrrolizidine alkaloid tumorige...

journal_title：Toxicology and industrial health

authors： Chou MW,Fu PP

更新日期：2006-09-01 00:00:00

abstract：:T-2 toxin is one of the mycotoxins, a group of type A trichothecenes produced by several fungal genera including Fusarium species, which may lead to the decrease of testosterone secretion in primary Leydig cells derived from mouse testis. The previous study demonstrated T-2 toxin decrease the testosterone biosynthesis...

journal_title：Toxicology and industrial health

authors： Yang JY,Zhang YF,Li YX,Guan GP,Kong XF,Liang AM,Ma KW,Da Li G,Bai XF

更新日期：2016-10-01 00:00:00