Co-registered pulse-echo/photoacoustic transvaginal probe for real time imaging of ovarian tissue.

abstract：:The aim of this study was to evaluate whether OCT topography of the Bowman's layer and artificial intelligence (AI) can result in better diagnosis of forme fruste (FFKC) and clinical keratoconus (KC). Normal (n = 221), FFKC (n = 72) and KC (n = 116) corneas were included. Some of the FFKC and KC patients had the fello...

journal_title：Journal of biophotonics

authors： Chandapura R,Salomão MQ,Ambrósio R Jr,Swarup R,Shetty R,Sinha Roy A

更新日期：2019-10-01 00:00:00

abstract：:Atherosclerosis is a process of thickening and stiffening of the arterial walls through the accumulation of lipids and fibrotic material, as a consequence of aging and unhealthy life style. However, not all arterial plaques lead to complications, which can lead to life-threatening events such as stroke and myocardial ...

journal_title：Journal of biophotonics

authors： Dugandžić V,Drikermann D,Ryabchykov O,Undisz A,Vilotijević I,Lorkowski S,Bocklitz TW,Matthäus C,Weber K,Cialla-May D,Popp J

更新日期：2018-12-01 00:00:00

abstract：:Monitoring living cells in real-time is important in order to unravel complex dynamic processes in life sciences. In particular the dynamics of initiation and progression of degenerative diseases is intensely studied. In atherosclerosis the thickening of arterial walls is related to high lipid levels in the blood stre...

journal_title：Journal of biophotonics

authors： Stiebing C,Meyer T,Rimke I,Matthäus C,Schmitt M,Lorkowski S,Popp J

更新日期：2017-09-01 00:00:00

abstract：:We report a compact, cost-effective tuned amplifier for frequency-selective amplification of the modulated signal in heterodyne detected nonlinear optical microscopy. Our method improved the signal to noise ratio by an order of magnitude compared to conventional lock-in detection, as demonstrated through stimulated Ra...

journal_title：Journal of biophotonics

authors： Slipchenko MN,Oglesbee RA,Zhang D,Wu W,Cheng JX

更新日期：2012-10-01 00:00:00

abstract：:Therapeutically exploiting vascular and metabolic endpoints becomes critical to translational cancer studies because altered vascularity and deregulated metabolism are two important cancer hallmarks. The metabolic and vascular phenotypes of three sibling breast tumor lines with different metastatic potential are inves...

journal_title：Journal of biophotonics

authors： Zhu C,Li M,Vincent T,Martin HL,Crouch BT,Martinez AF,Madonna MC,Palmer GM,Dewhirst MW,Ramanujam N

更新日期：2019-04-01 00:00:00

abstract：:We report the use of ultrasound modulated optical tomography (UOT) with heterodyne parallel detection to locally sense and image blood flow deep inside a highly scattering medium. We demonstrate that the UOT signal is sensitive to the speed of the blood flow in the ultrasound focus and present an analytical model that...

journal_title：Journal of biophotonics

authors： Hussain A,Steenbergen W,Vellekoop IM

更新日期：2018-01-01 00:00:00

abstract：:Previous studies for melanin visualization in the retinal pigment epithelium (RPE) have exploited either its absorption properties (using photoacoustic tomography or photothermal optical coherence tomography [OCT]) or its depolarization properties (using polarization sensitive OCT). However, these methods are only sui...

journal_title：Journal of biophotonics

authors： Harper DJ,Konegger T,Augustin M,Schützenberger K,Eugui P,Lichtenegger A,Merkle CW,Hitzenberger CK,Glösmann M,Baumann B

更新日期：2019-12-01 00:00:00

abstract：:This study presents numerical simulations of UVC light propagation through seven different filtered face respirators (FFR) to determine their suitability for Ultraviolet germicidal inactivation (UVGI). UV propagation was modeled using the FullMonte program for two external light illuminations. The optical properties o...

journal_title：Journal of biophotonics

authors： Lilge L,Manalac A,Weersink M,Schwiegelshohn F,Young-Schultz T,Abdalrhman AS,Wang C,Ngan A,Gu FX,Betz V,Hofmann R

更新日期：2020-12-01 00:00:00

abstract：:The ability to provide quantitative, objective and automated pathological analysis would provide enormous benefits for national cancer screening programmes, in terms of both resource reduction and improved patient wellbeing. The move towards molecular pathology through spectroscopic methods shows great promise, but ha...

journal_title：Journal of biophotonics

authors： Woolford L,Chen M,Dholakia K,Herrington CS

更新日期：2018-04-01 00:00:00

abstract：:We present a noninvasive and noncontacting biosensor using Wavelength Modulated Differential Photothermal Radiometry (WM-DPTR) to monitor blood glucose concentration (BGC) through interstitial fluid (ISF) probing in human middle fingers. WM-DPTR works in the interference-free mid-infrared range with differential wavel...

journal_title：Journal of biophotonics

authors： Guo X,Zhang D,Shojaei-Asanjan K,Sivagurunathan K,Melnikov A,Song P,Mandelis A

更新日期：2019-07-01 00:00:00

abstract：:Current elastography techniques are limited in application to accurately assess spatially resolved corneal elasticity in vivo for human eyes. The air-puff optical coherence elastography (OCE) with an eye motion artifacts correction algorithm is developed to distinguish the in vivo cornea vibration from the eye motion ...

journal_title：Journal of biophotonics

authors： Jin Z,Chen S,Dai Y,Bao C,Ye S,Zhou Y,Wang Y,Huang S,Wang Y,Shen M,Zhu D,Lu F

更新日期：2020-08-01 00:00:00

abstract：:In this work we aim to show how it is possible to exploit the second harmonic generation (SHG) signal for producing multimodal microscopic images of biological tissues. SHG microscopy constitutes an important tool for high-resolution, high-contrast, three-dimensional studies of live cell and tissue architectures. The ...

journal_title：Journal of biophotonics

authors： Bianchini P,Diaspro A

更新日期：2008-12-01 00:00:00

abstract：:Human immunodeficiency virus (HIV-1) infection remains a major health problem despite the use of highly active antiretroviral therapy (HAART), which has greatly reduced mortality rates. Due to the unavailability of an effective vaccine and treatment that would completely eradicate the virus in infected individuals, th...

journal_title：Journal of biophotonics

authors： Lugongolo MY,Manoto SL,Ombinda-Lemboumba S,Maaza M,Mthunzi-Kufa P

更新日期：2017-10-01 00:00:00

abstract：:The aim of this study is to identify changes in scattering with optical coherence tomography (OCT) and relate these measurements with mitochondrial changes during the initiation of apoptosis. Human retinal pigment epithelial cells were cultured and apoptosis was induced using 10% alcohol. Using the attenuation coeffic...

journal_title：Journal of biophotonics

authors： de Bruin DM,Broekgaarden M,van Gemert MJ,Heger M,de la Rosette JJ,Van Leeuwen TG,Faber DJ

更新日期：2016-09-01 00:00:00

abstract：:We developed an optical imaging method based on a feedback principle in which the specific scan pattern is adapted according to the shape of the sample. The feedback approach produces nanometer-resolved 3D images of very small and moving features in live cells in seconds. We show images of microvilli in live cultured ...

journal_title：Journal of biophotonics

authors： Lanzano L,Digman MA,Fwu P,Giral H,Levi M,Gratton E

更新日期：2011-06-01 00:00:00

abstract：:Surface-enhanced Raman scattering (SERS) is highly sensitive and label-free analytical technique based on Raman spectroscopy aided by field-multiplying plasmonic nanostructures. We report the use of SERS measurements of patient urine in conjunction with biostatistical algorithms to assess the treatment response of pro...

journal_title：Journal of biophotonics

authors： Ma Y,Chi J,Zheng Z,Attygalle A,Kim IY,Du H

更新日期：2021-01-01 00:00:00

abstract：:Molecular motors have been extensively studied over the past 25 years using a range of optical microscopy methods. The specific example of RNA polymerase, responsible for transcribing the information encoded in DNA into RNA, illustrates the strength of the convergence between these recent approaches and the vast store...

journal_title：Journal of biophotonics

authors： Strick TR

更新日期：2008-09-01 00:00:00

abstract：:Photoacoustic microscopy (PAM) provides a fundamentally new tool for a broad range of studies of biological structures and functions. However, the use of PAM has been largely limited to small vertebrates due to the large size/weight and the inconvenience of the equipment. Here, we describe a portable optical-resolutio...

journal_title：Journal of biophotonics

authors： Jin T,Guo H,Yao L,Xie H,Jiang H,Xi L

更新日期：2018-04-01 00:00:00

abstract：:Optical coherence tomography (OCT) imaging shows a significant potential in clinical routines due to its noninvasive property. However, the quality of OCT images is generally limited by inherent speckle noise of OCT imaging and low sampling rate. To obtain high signal-to-noise ratio (SNR) and high-resolution (HR) OCT ...

journal_title：Journal of biophotonics

authors： Qiu B,You Y,Huang Z,Meng X,Jiang Z,Zhou C,Liu G,Yang K,Ren Q,Lu Y

更新日期：2021-01-01 00:00:00

abstract：:Ectasia after refractive surgery represents a major concern among refractive surgeons. Corneal abnormalities and preexisting corneal ectasia are the most important risk factors. Corneal topography and central corneal thickness are the factors traditionally screening for in refractive surgery candidates. Study of the a...

journal_title：Journal of biophotonics

authors： Luz A,Lopes B,Salomão M,Ambrósio R

更新日期：2016-05-01 00:00:00

abstract：:The use of conventional fluorescence microscopy for characterizing tissue pathological states is limited by overlapping spectra and the dependence on excitation power and fluorophore concentration. Fluorescence lifetime imaging microscopy (FLIM) can overcome these limitations due to its insensitivity to fluorophore co...

journal_title：Journal of biophotonics

authors： Gu J,Fu CY,Ng BK,Gulam Razul Ss,Lim SK

更新日期：2014-07-01 00:00:00

abstract：:Microcalcifications are an early mammographic sign of breast cancer and a target for stereotactic breast needle biopsy. Here, we develop and compare different approaches for developing Raman classification algorithms to diagnose invasive and in situ breast cancer, fibrocystic change and fibroadenoma that can be associ...

journal_title：Journal of biophotonics

authors： Dingari NC,Barman I,Saha A,McGee S,Galindo LH,Liu W,Plecha D,Klein N,Dasari RR,Fitzmaurice M

更新日期：2013-04-01 00:00:00

abstract：:The paper presents a new algorithm based on some selected automatic quantitative methods for analysing thermal images. It shows the practical implementation of these image analysis methods in Matlab. It enables to perform fully automated and reproducible measurements of selected parameters in thermal images. The paper...

journal_title：Journal of biophotonics

authors： Koprowski R

更新日期：2016-05-01 00:00:00

abstract：:The structural organization of cellular membranes has an essential influence on their functionality. The membrane surfaces currently are considered to consist of various distinct patches, which play an important role in many processes, however, not all parameters such as size and distribution are fully determined. In ...

journal_title：Journal of biophotonics

authors： Deckert-Gaudig T,Böhme R,Freier E,Sebesta A,Merkendorf T,Popp J,Gerwert K,Deckert V

更新日期：2012-07-01 00:00:00

abstract：:To this day, any photosensitizers for the photodynamic treatment of pulmonary illnesses have been administered intravenously. There is, however, an intrinsic difficulty in reaching the target cells or bacteria in the respiratory system. Nebulization could overcome distribution problems and alleviate side effects by de...

journal_title：Journal of biophotonics

authors： Kassab G,Geralde MC,Inada NM,Achiles AE,Guerra VG,Bagnato VS

更新日期：2019-04-01 00:00:00

abstract：:In the current clinical care practice, Gleason grading system is one of the most powerful prognostic predictors for prostate cancer (PCa). The grading system is based on the architectural pattern of cancerous epithelium in histological images. However, the standard procedure of histological examination often involves ...

journal_title：Journal of biophotonics

authors： Yang Q,Xu Z,Liao C,Cai J,Huang Y,Chen H,Tao X,Huang Z,Chen J,Dong J,Zhu X

更新日期：2020-02-01 00:00:00

abstract：:For the screening purposes urine is an especially attractive biofluid, since it offers easy and noninvasive sample collection and provides a snapshot of the whole metabolic status of the organism, which may change under different pathological conditions. Raman spectroscopy (RS) has the potential to monitor these chang...

journal_title：Journal of biophotonics

authors： Žukovskaja O,Ryabchykov O,Straßburger M,Heinekamp T,Brakhage AA,Hennings CJ,Hübner CA,Wegmann M,Cialla-May D,Bocklitz TW,Weber K,Popp J

更新日期：2020-01-01 00:00:00

abstract：:223 Radium (223 Ra) is widely used in nuclear medicine to treat patients with osseous metastatic prostate cancer. In clinical practice 223 Ra cannot be imaged directly; however, gamma photons produced by its short-lived daughter nuclides can be captured by conventional gamma cameras. In this work, we show that 223 Ra ...

journal_title：Journal of biophotonics

authors： Boschi F,De Sanctis F,Spinelli AE

更新日期：2018-04-01 00:00:00

abstract：:Lasers are used in dentistry for a variety of indications. One of these is the disinfection of root canals or the sterilization of residual caries. Many studies have demonstrated the capacity to kill bacteria for lasers but the fundamental mechanism of the laser effect remains quite unclear. With our experiments we wa...

journal_title：Journal of biophotonics

authors： Hibst R,Graser R,Udart M,Stock K

更新日期：2010-06-01 00:00:00

abstract：:This contribution covers recent original research papers in the biophotonics field. The content is organized into main techniques such as multiphoton microscopy, Raman spectroscopy, infrared spectroscopy, optical coherence tomography and photoacoustic tomography, and their applications in the context of fluid, cell, t...

journal_title：Journal of biophotonics

authors： Krafft C

更新日期：2016-12-01 00:00:00