Developing a clinical-grade cryopreservation protocol for human testicular tissue and cells.

abstract：:The selection of the most relevant molecular descriptors to describe a target variable in the context of QSAR (Quantitative Structure-Activity Relationship) modelling is a challenging combinatorial optimization problem. In this paper, a novel software tool for addressing this task in the context of regression and clas...

journal_title：BioMed research international

authors： Martínez MJ,Razuc M,Ponzoni I

更新日期：2019-02-17 00:00:00

abstract：Background:Many studies, comparing the health associated risks of electronic cigarettes with conventional cigarettes focus mainly on the common chemical compounds found between them. Aim:Review chemical compounds found exclusively in electronic cigarettes and describe their toxic effects, focusing on electronic-cigare...

journal_title：BioMed research international

authors： Armendáriz-Castillo I,Guerrero S,Vera-Guapi A,Cevallos-Vilatuña T,García-Cárdenas JM,Guevara-Ramírez P,López-Cortés A,Pérez-Villa A,Yumiceba V,Zambrano AK,Leone PE,Paz-Y-Miño C

更新日期：2019-12-19 00:00:00

abstract：:We previously found that the greatest salivation response in healthy human subjects is produced by facial vibrotactile stimulation of 89 Hz frequency with 1.9 μ m amplitude (89 Hz-S), as reported by Hiraba et al. (2012, 20011, and 2008). We assessed relationships between the blood flow to brain via functional near-inf...

journal_title：BioMed research international

authors： Hiraba H,Inoue M,Gora K,Sato T,Nishimura S,Yamaoka M,Kumakura A,Ono S,Wakasa H,Nakayama E,Abe K,Ueda K

更新日期：2014-01-01 00:00:00

abstract：:Chronic obstructive pulmonary disease (COPD) features chronic inflammatory reactions of both intra- and extrapulmonary nature. Moreover, COPD is associated with abnormal glucose and lipid metabolism in patients, which influences the prognosis and chronicity of this disease. Abnormal glucose and lipid metabolism are al...

journal_title：BioMed research international

authors： Li J,Lu Y,Li N,Li P,Wang Z,Ting W,Liu X,Wu W

更新日期：2020-04-06 00:00:00

abstract：:The aim of this study is to investigate the stress distributions of different restoration options for class II mesio-occluso-distal (MOD) cavities. A class II MOD cavity with proximal box gingival floor 1 mm below cementoenamel junction was designed in a mandibular first molar tooth model. 3D finite-element analysis (...

journal_title：BioMed research international

authors： Alp Ş,Gulec Alagoz L,Ulusoy N

更新日期：2020-12-15 00:00:00

abstract：Objective:The use of a biofabrication nerve scaffold, which mimics the nerve microstructure, as an alternative for autologous nerve transplantation is a promising strategy for treating peripheral nerve defects. This study aimed to design a customized biofabrication scaffold model with the characteristics of human perip...

journal_title：BioMed research international

authors： Yao Z,Yan LW,Qiu S,He FL,Gu FB,Liu XL,Qi J,Zhu QT

更新日期：2019-12-14 00:00:00

abstract：INTRODUCTION:Deep vein thrombosis (DVT) is a severe complication after total hip arthroplasty (THA). It leads to acute pulmonary embolism, a life-threatening disease. P-selectin is a 140-kDa transmembrane glycoprotein. Elevated P-selectin was associated with 1.7-fold increase in the risk of venous thrombosis. MATERIAL...

journal_title：BioMed research international

authors： Shi D,Xu X,Xu Z,Nakamura T,Pang Y,Yao C,Wang F,Chen D,Dai J,Jiang Q

更新日期：2014-01-01 00:00:00

abstract：:Secretory leukoprotease inhibitor (SLPI) is an anti-inflammatory protein present in respiratory secretions. Whilst epithelial cell SLPI is extensively studied, neutrophil associated SLPI is poorly characterised. Neutrophil function including chemotaxis and degranulation of proteolytic enzymes involves changes in cytos...

journal_title：BioMed research international

authors： Reeves EP,Banville N,Ryan DM,O'Reilly N,Bergin DA,Pohl K,Molloy K,McElvaney OJ,Alsaleh K,Aljorfi A,Kandalaft O,O'Flynn E,Geraghty P,O'Neill SJ,McElvaney NG

更新日期：2013-01-01 00:00:00

abstract：Background:The predictive values of monocytes in the prognosis of patients with acute paraquat (PQ) poisoning are unclear. This retrospective study investigated the predictive values of monocytes in the prognosis of patients with acute PQ poisoning. Methods:Adult patients who suffered from acute PQ poisoning in the em...

journal_title：BioMed research international

authors： Zhao Y,Song YQ,Gao J,Feng SY,Li Y

更新日期：2019-07-15 00:00:00

abstract：:Blood compatibility of metallocene polyethylene (mPE) was investigated after modifying the surface using hydrochloric acid. Contact angle of the mPE exposed to HCl poses a decrease in its value which indicates increasing wettability and better blood compatibility. Surface of mPE analyzed by using FTIR revealed no sign...

journal_title：BioMed research international

authors： Jaganathan SK,Mohandas H,Sivakumar G,Kasi P,Sudheer T,Avineri Veetil S,Murugesan S,Supriyanto E

更新日期：2014-01-01 00:00:00

abstract：:In spite of the declining incidence of gastric cancer (GC) in recent years, the mortality rate is still high. The asymptomatic nature and nonspecific clinical manifestations combined with the lack of efficient screening programs delay the diagnosis of GC. Therefore, the prevalence of advanced gastric cancer (AGC) has ...

journal_title：BioMed research international

authors： Xu W,Beeharry MK,Liu W,Yan M,Zhu Z

更新日期：2016-01-01 00:00:00

abstract：:Induced pluripotent stem cells (iPSC) hold tremendous potential for personalized cell-based therapy for skin regeneration. Aiming to establish human iPSCs as a potential cell source for skin tissue engineering, we expect to obtain an epidermal-like cell line with angiogenic and keratinogenic differentiation potential ...

journal_title：BioMed research international

authors： Lin W,Chen M,Hu C,Qin S,Chu C,Xiang L,Man Y,Qu Y

更新日期：2018-09-13 00:00:00

abstract：:Growing evidence indicates that immune-related biomarkers play an important role in tumor processes. This study investigates immune-related gene expression and its prognostic value in lung squamous cell carcinoma (LUSC). A cohort of 493 samples of patients with LUSC was collected and analyzed from data generated by th...

journal_title：BioMed research international

authors： Yan Y,Zhang M,Xu S,Xu S

更新日期：2020-06-27 00:00:00

abstract：:Background. With the introduction of three-dimensional (3D) ultrasound it has become possible to measure volumes. The relative increase in embryonic volume (EV) is much larger than that of the crown-rump length (CRL) over the same time period. We examined whether EV is a better parameter to determine growth restrictio...

journal_title：BioMed research international

authors： Baken L,Benoit B,Koning AHJ,van der Spek PJ,Steegers EAP,Exalto N

更新日期：2017-01-01 00:00:00

abstract：:Impact of bone mesenchymal stem cell (BMSC) transfusion on chronic smoking-induced lung inflammation is poorly understood. In this study, a rat model of smoking-related lung injury was induced and the rats were treated with vehicle or BMSCs for two weeks. Different subsets of CD4+ T cells, cytokines, and anti-elastin ...

journal_title：BioMed research international

authors： Li X,Wang J,Cao J,Ma L,Xu J

更新日期：2015-01-01 00:00:00

abstract：:Although disorders of the stomatognathic system are common, the mechanisms involved are unknown. Our objective was to study the changes in the masseter muscles after unilateral exodontia. Molar extraction was performed on Wistar rats (left side), and the animals were sacrificed after either 14 or 26 days. The masseter...

journal_title：BioMed research international

authors： Guerra Cde S,Carla Lara Pereira Y,Issa JP,Luiz KG,Guimarães EA,Gerlach RF,Iyomasa MM

更新日期：2014-01-01 00:00:00

abstract：:Rhabdoid tumor of the kidney (RTK) is a rare and severely malignant tumor occurring in infancy and early childhood, with the overall outcomes remain poor. Neither gene regulatory networks nor biomarkers to predict the prognostic outcomes have been elucidated in RTK. In this study, RNA sequencing data were obtained to ...

journal_title：BioMed research international

authors： Wang X,Wu X,Li T,Cui M,Zhu L,Wang G,Guo F

更新日期：2020-08-26 00:00:00

abstract：Background:The apolipoprotein E knockout (ApoE -/-) mouse model is well established for the study of terpenoids in the prevention of atherosclerosis. Studies investigating the clinical benefit of terpenoids in humans are scarce. This systematic review and meta-analysis evaluated the effects of terpenoid administration ...

journal_title：BioMed research international

authors： Liu H,Zhang Y,Sun S,Wang S

更新日期：2019-07-17 00:00:00

abstract：:MicroRNAs (miRNAs) family, which is involved in cancer development, proliferation, apoptosis, and drug resistance, is a group of noncoding RNAs that modulate the expression of oncogenes and antioncogenes. Doxorubicin is an active cytotoxic agent for breast cancer treatment, but the acquisition of doxorubicin resistanc...

journal_title：BioMed research international

authors： Long J,Ji Z,Jiang K,Wang Z,Meng G

更新日期：2015-01-01 00:00:00

abstract：:Myopia is the most common ocular abnormality. Its high and growing prevalence has contributed to a recent surge in surgical interest in the disorder, since retinal detachment in eyes with high myopia differs from that in emmetropic eyes or eyes with low myopia. The myopic eye, because of its specific anatomy, poses sp...

journal_title：BioMed research international

authors： Semeraro F,Morescalchi F,Russo A,Romano MR,Costagliola C

更新日期：2014-01-01 00:00:00

abstract：:A 35 KDa protein referred to as F3 was purified from the seeds of Borreria hispida by precipitation with 80% ammonium sulphate and gel filtration on Sephadex G-100 column. RP-HPLC analysis of protein fraction (F3) on an analytical C-18 column produced a single peak, detected at 220 nm. F3 showed an apparent molecular ...

journal_title：BioMed research international

authors： Rupachandra S,Sarada DV

更新日期：2014-01-01 00:00:00

abstract：Objective:To analyze the ten-year surgical outcomes and postoperative complications of French-Door laminoplasty (FDL) in the management of multilevel cervical spondylotic myelopathy (MCSM) and analyze the prognostic factors for FDL in treating MCSM. Methods:64 patients with MCSM, who were operated by FDL, were include...

journal_title：BioMed research international

authors： Chen G,Liu X,Chen N,Chen B,Zou X,Wei F,Liu S

更新日期：2020-05-06 00:00:00

abstract：:Liver cell culture within three-dimensional structures provides an improved culture system for various applications in basic research, pharmacological screening, and implantable or extracorporeal liver support. Biodegradable calcium-based scaffolds in such systems could enhance liver cell functionality by providing en...

journal_title：BioMed research international

authors： Finoli A,Schmelzer E,Over P,Nettleship I,Gerlach JC

更新日期：2016-01-01 00:00:00

abstract：:Peroxisome proliferators-activated receptor (PPAR) gene family members exhibit distinct patterns of distribution in tissues and differ in functions. The purpose of this study is to investigate the evolutionary impacts on diversity functions of PPAR members and the regulatory differences on gene expression patterns. 63...

journal_title：BioMed research international

authors： Zhou T,Yan X,Wang G,Liu H,Gan X,Zhang T,Wang J,Li L

更新日期：2015-01-01 00:00:00

abstract：:Hepatitis B virus (HBV) is an important public health problem that poses a serious threat to human health. HBV reactivation generally occurs in overt or occult HBV infection patients who suffered DDAs, chemotherapy, or immunosuppressive therapy, especially when some solid tumors and leukemia patients are using hormone...

journal_title：BioMed research international

authors： Guo L,Wang D,Ouyang X,Tang N,Chen X,Zhang Y,Zhu H,Li X

更新日期：2018-12-26 00:00:00

abstract：INTRODUCTION:The PiCCO transpulmonary thermodilution technique provides two indices of cardiac systolic function, the cardiac function index (CFI) and the global ejection fraction (GEF). Both appear to be correlated with left ventricular ejection fraction (LVEF) measured by echocardiography in patients with circulatory...

journal_title：BioMed research international

authors： Perny J,Kimmoun A,Perez P,Levy B

更新日期：2014-01-01 00:00:00

abstract：:Duchenne muscular dystrophy (DMD), the most common form of muscular dystrophy, is characterized by muscular wasting caused by dystrophin deficiency that ultimately ends in force reduction and premature death. In addition to primary genetic defect, several mechanisms contribute to DMD pathogenesis. Recently, antioxidan...

journal_title：BioMed research international

authors： Sitzia C,Farini A,Colleoni F,Fortunato F,Razini P,Erratico S,Tavelli A,Fabrizi F,Belicchi M,Meregalli M,Comi G,Torrente Y

更新日期：2015-01-01 00:00:00

abstract：:Erythrocytes deformation is one of the exciting properties of erythrocytes. It is still under investigation by many of the researchers in different disciplines. The clinicians and researchers are still looking for a simple and efficient method to monitor and tracking the erythrocytes deformation. This research article...

journal_title：BioMed research international

authors： Elblbesy MA

更新日期：2018-10-24 00:00:00

abstract：:Previous studies have linked systemic glucocorticoid use with intestinal perforation. However, the association between intestinal perforation and endogenous hypercortisolism has not been well described, with only 14 previously published case reports. In this study, we investigated if intestinal perforation occurred mo...

journal_title：BioMed research international

authors： Shahidi M,Phillips RA,Chik CL

更新日期：2019-03-13 00:00:00

abstract：Introduction:Even today, despite medical progress and intensive health education, odontogenic infections leading to surgical intervention and hospitalization are common in children and young people. The aim of this study was to give a detailed overview of clinical and economic data on children and young people treated ...

journal_title：BioMed research international

authors： Doll C,Carl F,Neumann K,Voss JO,Hartwig S,Waluga R,Heiland M,Raguse JD

更新日期：2018-08-26 00:00:00