Abstract：
:People with major depressive disorder (MDD) have an increased burden of chronic physical illnesses (CPI). However, information about the effect of CPIs on recurrent MDD treatment outcome is limited. The objective of this study was to explore whether the number of CPIs in patients with recurrent MDD was associated with higher rate of psychiatric admissions. Data were collected for a consecutive sample of 190 patients diagnosed with recurrent MDD. The key outcome was the number of psychiatric admissions following psychiatric diagnosis. The independent variable was the number of CPIs. The effects of different clinical, sociodemographic, and lifestyle confounding factors were controlled using robust regression. The patients with CPI had significantly more psychiatric admissions than the patients without CPI, and the number of CPIs was significantly associated with the number of psychiatric admissions. The results of our study largely confirmed that more than two CPIs in patients diagnosed with recurrent MDD are associated with higher rates of psychiatric admission, independent of psychiatric comorbidities and other clinical and sociodemographic factors. These findings indicate that to improve treatment outcome and to reduce recurrence, it is crucial to enhance early recognition and treatment of physical comorbidity.
journal_name
Psychiatry Resjournal_title
Psychiatry researchauthors
Šimunović Filipčić I,Filipčić I,Glamuzina L,Devčić S,Bajić Ž,Braš M,Mihaljević Peleš A,Marčinko D,Sartorius Ndoi
10.1016/j.psychres.2018.12.178subject
Has Abstractpub_date
2019-02-01 00:00:00pages
602-608eissn
0165-1781issn
1872-7123pii
S0165-1781(18)31042-4journal_volume
272pub_type
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