The antimicrobial activity of lapachol and its thiosemicarbazone and semicarbazone derivatives.

abstract：:More sensitive methodologies are necessary to improve strongyloidiasis diagnosis. This study compared the sensitivities of the McMaster modified technique and polymerase chain reaction (PCR) assays, both performed in faecal samples. Lewis rats were subcutaneously infected with 4,000, 400 or 40 infective third-stage la...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Marra NM,Chiuso-Minicucci F,Machado GC,Zorzella-Pezavento SF,França TG,Ishikawa LL,Amarante AF,Sartori A,Amarante MR

更新日期：2010-02-01 00:00:00

abstract：:An experimental model for acquired and congenital ocular toxoplasmosis as well as a model to induce experimental autoimmune uveitis (EAU) was investigated in Calomys callosus. Toxoplasma gondii, ME-49 strain, was used to infect males and pregnant- and not pregnant-females while S-antigen, a major glycoprotein of the r...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pereira Mde F,Silva DA,Ferro EA,Mineo JR

更新日期：1999-01-01 00:00:00

abstract：:In this study, HIV-1 viral blood quantitation determined by Nucleic Acid Sequence Based Amplification (NASBA) was compared with other surrogate disease progression markers (antigen p24, CD4/CD8 cell counts and beta-2 microglobulin) in 540 patients followed up at São Paulo, SP, Brazil. HIV-1 RNA detection was statistic...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Sitnik R,Pinho JR

更新日期：1998-05-01 00:00:00

abstract：:The trypanosomatid cytoskeleton is responsible for the parasite's shape and it is modulated throughout the different stages of the parasite's life cycle. When parasites are exposed to media with reduced osmolarity, they initially swell, but subsequently undergo compensatory shrinking referred to as regulatory volume d...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Dagger F,Valdivieso E,Marcano AK,Ayesta C

更新日期：2013-02-01 00:00:00

abstract：:Aspartyl proteases are a class of enzymes that include the yeast aspartyl proteases and secreted aspartyl protease (Sap) superfamilies. Several Sap superfamily members have been demonstrated or suggested as virulence factors in opportunistic pathogens of the genus Candida. Candida albicans, Candida tropicalis, Candida...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Parra-Ortega B,Cruz-Torres H,Villa-Tanaca L,Hernández-Rodríguez C

更新日期：2009-05-01 00:00:00

abstract：:Some species of Amphibia and Reptilia are listed as new hosts of spargana, from material deposited in the Helminthological Collection of Oswaldo Cruz Institute. It is discussed the difficulties in identifying the larvae (Sparganum) and also the identification of adults of Luheella species from South America. The histo...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Rego AA,Schäffer GV

更新日期：1992-01-01 00:00:00

abstract：:Non-bilayer phospholipid arrangements are three-dimensional structures that form when anionic phospholipids with an intermediate structure of the tubular hexagonal phase II are present in a bilayer of lipids. Antibodies that recognise these arrangements have been described in patients with antiphospholipid syndrome an...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Baeza I,Wong-Baeza C,Valerdi E,Serafin-Lopez J,Ibáñez M,Estrada-Parra S,Wong C,Estrada-Garcia I

更新日期：2012-12-01 00:00:00

abstract：:In schistosomiasis, the host/parasite interaction remains not completely understood. Many questions related to the susceptibility of snails to infection by respective trematode still remain unanswered. The control of schistosomiasis requires a good understanding of the host/parasite association. In this work, the susc...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Abdel-Hamid AH,Rawi SM,Arafa AF

更新日期：2006-12-01 00:00:00

abstract：:In this article, Médicos Sin Fronteras (MSF) Spain faces the challenge of selecting, piecing together, and conveying in the clearest possible way, the main lessons learnt over the course of the last seven years in the world of medical care for Chagas disease. More than two thousand children under the age of 14 have be...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Villa L,Morote S,Bernal O,Bulla D,Albajar-Vinas P

更新日期：2007-10-30 00:00:00

abstract：BACKGROUND:Gene reporter-fluorescent cells have emerged as alternative method for drug screening. OBJECTIVE:Achievement of constitutive expression of fluorescent protein GFP by Leishmania braziliensis as alternative method for drug screening. METHODS:L. braziliensis-GFP was generated using Leishmania tarentolae pLEXS...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bastos MS,Souza LÂ,Onofre TS,Silva A Júnior,Almeida MR,Bressan GC,Fietto JL

更新日期：2017-02-01 00:00:00

abstract：:Different molecular-genetic methods were used to identify a cohort of Leishmania strains from natural foci of zoonotic cutaneous leishmaniasis located in Central Asia, on the former USSR territory. The results obtained using isoenzymes, PCR, restriction fragment length polymorphisms of kDNA and molecular hybridization...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Strelkova MV,Pacheco RS,Bulat SA,Rakitskaya TA

更新日期：1997-01-01 00:00:00

abstract：:This study examined whether the antidermatophytic activity of essential oils (EOs) can be used as an indicator for the discovery of active natural products against Leishmania amazonensis. The aerial parts of seven plants were hydrodistilled. Using broth microdilution techniques, the obtained EOs were tested against th...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Houël E,Gonzalez G,Bessière JM,Odonne G,Eparvier V,Deharo E,Stien D

更新日期：2015-02-01 00:00:00

abstract：:We used a slide culture technique to detect tubercle bacilli surviving in sputum smears (n=46) after conventional heat fixation and Ziehl-Neelsen staining. In all heat-fixed sputum smears, tubercle bacilli survived after time 0 (n=22), 24 h (n=7), 48 h (n=7), 72 h (n=4), and seven days (n=6). None of the stained sputu...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cardoso CL,Giacomelli LR,Helbel C,Sant'Ana JJ,Martins FM,Barreto AM

更新日期：2001-02-01 00:00:00

abstract：:The study was set up to evaluate the impact of two commercial larvicide formulations, Bacillus thuringiensis serovar israelensis base (Bti) at 15 ppm/1 min and temephos at 0.03 ppm of active ingredient, used to control Simulium pertinax populations, on associated non-target entomofauna occupying the same breeding site...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： de Araújo-Coutinho CJ,Cunha Ade B,Serra-Freire NM,de Mello RP

更新日期：2003-07-01 00:00:00

abstract：:Trypanosoma rangeli, a parasite generally considered non-pathogenic for man, is the second species of human trypanosome to be reported from the New World. The geographical distribution of T. rangeli often overlaps with that of T. cruzi, the same vertebrate and invertebrate hosts being infected. Their differentiation t...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Guhl F,Vallejo GA

更新日期：2003-06-01 00:00:00

abstract：:Anti-human immunodeficiency virus type 1 (HIV-1) "binding antibodies" (antibodies capable of binding to synthetic peptides or proteins) occur throughout HIV-1 infection, are high-titered and highly cross-reactive, as confirmed in this study by analyzing plasma from B and F genotype HIV-1 infected individuals. Plasma f...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bongertz V,Teixeira SL,Grinztejn B,Pilotto JH,Veloso VG,Morgado MG,Bastos FI,Ouverney EP

更新日期：2005-02-01 00:00:00

abstract：:Host lipids have been implicated in the pathogenesis of Toxoplasma gondii infection. To determine if Toxoplasma infection influences the lipid status in the normal host, we assessed serum lipids of Swiss-Webster mice during infection with the BGD-1 strain (type-2) at a series of time points. Mice were bled at days zer...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Milovanović I,Vujanić M,Klun I,Bobić B,Nikolić A,Ivović V,Trbovich AM,Djurković-Djaković O

更新日期：2009-03-01 00:00:00

abstract：:In Argentina, most information on hepatitis C virus (HCV) genotype distribution comes from studies carried out in Buenos Aires (east province). In order to identify HCV subtypes in central Argentina, nucleotide sequencing of core region was performed in samples from 36 patients living in Córdoba, the second most popul...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ré V,Contigiani M,Yoshida CF,Lampe E

更新日期：2007-12-01 00:00:00

abstract：:Clinical and laboratory evidence is reviewed which shows that there is a great deal of variation in the susceptibility of Schistosoma mansoni to oxamniquine. This variation occurs both among endemic regions and within endemic regions in Brazil and Kenya. It is genetically controlled. It is suggested that the parasite ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Kinoti GK

更新日期：1987-01-01 00:00:00

abstract：:In a previous study, the Schistosoma mansoni Rho1 protein was able to complement Rho1 null mutant Saccharomyces cerevisiae cells at restrictive temperatures and under osmotic stress (low calcium concentration) better than the human homologue (RhoA). It is known that under osmotic stress, the S. cerevisiae Rho1 trigger...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Aguiar PH,Santos DN,Lobo FP,Santos TM,Macedo AM,Pena SD,Machado CR,Franco GR

更新日期：2006-09-01 00:00:00

abstract：:Rhesus monkeys (Macaca mulatta) were infected subcutaneously with 1.0 x 10(4) to 1.5 x 10(4) metacyclic trypomastigotes of Trypanosoma cruzi (Colombian strain). Parasitological and immunological parameters were evaluated in these animals for periods of 1 month to over 3 years. A chagoma was observed between the 3rd an...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bonecini-Almeida Mda G,Galvão-Castro B,Pessoa MH,Pirmez C,Laranja F

更新日期：1990-04-01 00:00:00

abstract：:The community structure of insects, especially mosquito larvae, in water held in the fungus Aquascypha hydrophora (Berk.) Reid (Stereaceae) is reported. The study was done in the Adolpho Ducke Forest Reserve, 26 km east of Manaus, AM, Brazil, from September 1998 through November 1999. The most abundant entomofauna wer...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ferreira RL,Oliveira AF,Pereira ES,Hamada N

更新日期：2001-11-01 00:00:00

abstract：:We report the first two cases of Trichosporon mycotoxinivorans infections in Latin America. We also conducted a literature review and a microbiological investigation, including that of clinical and environmental isolates. A 30-year-old man with chronic renal failure had disseminated infection after dialysis and a 15-y...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Almeida JN Jr,Francisco EC,Barberino MGMA,Silva LVRFD Filho,Brandão OM,Colombo AL,Padovan ACB

更新日期：2017-10-01 00:00:00

abstract：:Mutations in the katG gene have been identified and correlated with isoniazid (INH) resistance in Mycobacterium tuberculosis isolates. The mutation AGC-->ACC (Ser-->Thr) at katG315 has been reported to be the most frequent and is associated with transmission and multidrug resistance. Rapid detection of this mutation c...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Verza M,Maschmann Rde A,Silva MS,Dalla Costa ER,Ribeiro MO,Rosso F,Suffys PN,Tortoli E,Marcelli F,Zaha A,Rossetti ML

更新日期：2009-08-01 00:00:00

abstract：:The global malaria situation has scarcely improved in the last 100 years, despite major advances in our knowledge of the basic biology, epidemiology and clinical basis of the disease. Effective malaria control, leading to a significant decrease in the morbidity and mortality attributable to malaria, will require a mul...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Riley EM

更新日期：2000-01-01 00:00:00

abstract：:The lymneid snail Lymnaea bogotensis Pilsbry 1935 is synonymized with L. cousini Jousseaume 1887, based on morphological comparisons of the reproductive systems. The shell, renal tube, and reproductive system are described and illustrated from specimens collected in the type locality and the municipality of Paipa, Col...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Velásquez LE

更新日期：2006-11-01 00:00:00

abstract：:The aim of this study was to determine the presence of Helicobacter pylori cytotoxin-associated gene (cagA)/vacuolating cytotoxin gene (vacA) among patients with chronic gastritis in Cuba and Venezuela. Gastric antrum biopsies were taken for culture, DNA extraction and PCR analysis. Amplification of vacA and cagA segm...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ortiz-Princz D,Guariglia-Oropeza V,Avila M,Correnti M,Perrone M,Gutierrez B,Torres J,Megraud F,Cavazza ME

更新日期：2010-05-01 00:00:00

abstract：:This is the first report on occurrence of Biomphalaria straminea in the district of São José de Almeida (municipality of Jaboticatubas) State of Minas Gerais, Brazil. The presence of B. glabrata and B. tenagophila had already been reported in this area. Such municipality is part of the metropolitan region of Belo Hori...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Massara CL,Carvalho Odos S,Caldeira RL,Jannotti-Passos LK,Schall VT

更新日期：2002-01-01 00:00:00

abstract：:In Brazil, malaria still remains a clinically important febrile syndrome for local populations and travelers, occurring mostly in the Amazon Basin. This review aims to report the main efforts employed to control this disease since the 1940s and the emergence of Plasmodium falciparum and Plasmodium vivax chemoresistanc...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Gama BE,Lacerda MV,Daniel-Ribeiro CT,Ferreira-da-Cruz Mde F

更新日期：2011-08-01 00:00:00

abstract：:Facilitated and improved by advances in molecular biology, techniques for the immunodiagnosis of schistosomiasis, including assays based on the detection of antigens circulating in the serum and/or excreted in the urine, have now reached the stage of multi-centre trials. There is a need to complement parasitological t...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bergquist NR

更新日期：1992-01-01 00:00:00