Access to diagnosis and treatment of Chagas disease/infection in endemic and non-endemic countries in the XXI century.

abstract：:Only one drug is currently available for the treatment and control of schistosomiasis and the increasing risk of selecting strains of schistosome that are resistant to praziquantel means that the development of new drugs is urgent. With this objective we have chosen to target the enzymes modifying histones and in part...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pierce RJ,Dubois-Abdesselem F,Caby S,Trolet J,Lancelot J,Oger F,Bertheaume N,Roger E

更新日期：2011-11-01 00:00:00

abstract：:Given their medical and veterinary relevance, the members of the Pipiens Assemblage are a worldwide target of ecological research. The distribution of Culex pipiens s.s. and Cx. quinquefasciatus converge in Buenos Aires, Argentina, where hybrids have been detected. Each member of the assemblage exhibits a distinct eco...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cardo MV,Rubio A,Junges M,Vezzani D,Carbajo AE

更新日期：2016-11-01 00:00:00

abstract：:The four dominant outer membrane proteins (46, 38, 33 and 28 kDa) were detected by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) in a semi-purified preparation of vesicle membranes of a Neisseria meningitidis (N44/89, B:4:P1.15:P5.5,7) strain isolated in Brazil. The N-terminal amino acid sequenc...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： De Simone SG,Soares SA,Souza AL,Danelli MG

更新日期：1996-01-01 00:00:00

abstract：:The Kilombero Malaria Project (KMP) attempts to define operationally useful indicators of levels of transmission and disease and health system relevant monitoring indicators to evaluate the impact of disease control at the community or health facility level. The KMP is a longitudinal community based study (N = 1024) i...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Teuscher T

更新日期：1992-01-01 00:00:00

abstract：:A shift from large to small average sizes was observed in Triatoma infestans and Rhodnius domesticus between field and domestic (or laboratory) conditions of life. It was more pronounced in the female specimens, leading to a subsequent reduction of sexual size dimorphism. This feature is discussed in terms of genetic ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Dujardin J,Steinden M,Chavez T,Machane M,Schofield C

更新日期：1999-07-01 00:00:00

abstract：:Lymphatic filariasis caused by nematode parasites Wuchereria bancrofti or Brugia malayi is a spectral disease and produces wide range of immune responses and varying levels of microfilaraemia in infected individuals. The relationship between the immune response of host and the developmental stage of the parasite as we...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Athisaya Mary K,Hoti S,Paily K

更新日期：2006-05-01 00:00:00

abstract：:Dissection of Lutzomyia longipalpis, captured in the São Luis focus of visceral Leishmaniasis revealed a 1.8% promastigote infection rate. ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ryan L,Brazil RP

更新日期：1984-07-01 00:00:00

abstract：:The diagnosis of human cutaneous leishmaniasis in small towns is sometimes made without the species identification of the Leishmania, even in areas without previous epidemiological surveys. Here we report the isolation of a Leishmania strain from a patient of Rincão, state of São Paulo, that was identified by isoenzym...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Pinto MC,Rosa JA,Fernandes ZM,Graminha MA,Mine JC,Allegretti SM,Delort S,Riedel C,Paes EL,Cupolillo E

更新日期：2005-11-01 00:00:00

abstract：:A massive and homogeneous amount of amastigote-like forms was detected in the stomodeal valve (SV) and the thoracic mid-gut (TMG) of Leishmania major-infected Phlebotomus papatasi, which received a second blood meal 13 to 21 days post-infection on healthy anaesthetized hamsters. After re-feeding, the infected sand fli...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Añez N,Tang Y,Rojas A,Crisante G,Killick-Kendrick M,Killick-Kendrick R

更新日期：2003-06-01 00:00:00

abstract：:Chagas heart disease (CHD) results from infection with the protozoan parasite Trypanosoma cruzi and is the leading cause of infectious myocarditis worldwide. It poses a substantial public health burden due to high morbidity and mortality. CHD is also the most serious and frequent manifestation of chronic Chagas diseas...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Rassi A Jr,Rassi A,Marin-Neto JA

更新日期：2009-07-01 00:00:00

abstract：:In this study, HIV-1 viral blood quantitation determined by Nucleic Acid Sequence Based Amplification (NASBA) was compared with other surrogate disease progression markers (antigen p24, CD4/CD8 cell counts and beta-2 microglobulin) in 540 patients followed up at São Paulo, SP, Brazil. HIV-1 RNA detection was statistic...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Sitnik R,Pinho JR

更新日期：1998-05-01 00:00:00

abstract：:Mitochondrial DNA of Biomphalaria tenagophila, a mollusc intermediate host of Schistosoma mansoni in Brazil, was sequenced and characterised. The genome size found for B. tenagophila was 13,722 bp and contained 13 messenger RNAs, 22 transfer RNAs (tRNA) and two ribosomal RNAs (rRNA). In addition to sequencing, the mit...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Jannotti-Passos LK,Ruiz JC,Caldeira RL,Murta SM,Coelho PM,Carvalho OS

更新日期：2010-07-01 00:00:00

abstract：:To study changes in survival, in biological activities and behavior of planorbids submitted to increased hydrostatic pressure, we developed a technique using two transparent chambers and a hydraulic piston. The apparatus permitted renewal of the liquid medium without substantial variations in pressure, thus eliminatin...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Jurberg P,Soares MS,Mascitelli AC,Favre TC,Barbosa JV

更新日期：1988-01-01 00:00:00

abstract：:A large bibliographic survey provided data on Trypanosoma cruzi serology covering the period 1948-1984. Epidemiological-demographic methods provided an estimate of 11% for the prevalence of positive serology in Brazil, by 1984. Significant temporal trends were observed for most of the Brazilian geographical regions as...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Feitosa MF,Krieger H

更新日期：1991-04-01 00:00:00

abstract：:Tissue invasion and pathology by Trypanosoma cruzi result from an interaction between parasite virulence and host immunity. Successive in vivo generations of the parasite select populations with increasing ability to invade the host. Conversely, prolonged in vitro selection of the parasite produces attenuated sublines...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Basombrío MA,Segura MA,Gómez L,Padilla M

更新日期：2000-01-01 00:00:00

abstract：:Forty-four marsupials, 77 rodents and 161 ticks were captured in an Atlantic Forest Reserve in Cotia county, State of São Paulo, where human cases of Lyme disease (LD) simile were reported. Twenty-one borrelia-like spirochete isolates were recovered from the mammals' blood and rodent livers or spleens, and triturated ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Abel IS,Marzagão G,Yoshinari NH,Schumaker TT

更新日期：2000-09-01 00:00:00

abstract：:Soluble antigens (Ag) from Paracoccidioides brasiliensis, Histoplasma capsulatum and Aspergillus fumigatus were prepared and standardized by double immunodiffusion (DID) and immunoelectroosmophoresis (IEOP). No difference in sensitivity was observed between the two techniques; 100% of standard patient sera were positi...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ferreira-da-Cruz MF,Galvão-Castro B,Wanke B

更新日期：1985-07-01 00:00:00

abstract：:Peritoneal exudate cells from mice infected with Schistosoma mansoni (S-PEC) can kill schistosomula in vitro in the presence of immune serum. S-PEC produce a low level of respiratory burst, and schistosomula mortality in their presence is not reduced when exogenous antioxidants are added, suggesting that with S-PEC, o...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Smith JM,Mikoji GM,Prichard RK

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Zika virus (ZIKV) was recognised as a zoonotic pathogen in Africa and southeastern Asia. Human infections were infrequently reported until 2007, when the first known epidemic occurred in Micronesia. After 2013, the Asian lineage of ZIKV spread along the Pacific Islands and Americas, causing severe outbreaks ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Freire CCM,Palmisano G,Braconi CT,Cugola FR,Russo FB,Beltrão-Braga PC,Iamarino A,Lima Neto DF,Sall AA,Rosa-Fernandes L,Larsen MR,Zanotto PMA

更新日期：2018-05-10 00:00:00

abstract：:In recent years, the development of new tools to gather field information about vector ecological parameters has increased. This report evaluated the BG-Sentinel Trap (BGS-Trap), a promising new attempt to improve collection of the dengue vector, Aedes aegypti. The efficacy of the BGS-Trap was compared with the CDC ba...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Maciel-de-Freitas R,Eiras AE,Lourenço-de-Oliveira R

更新日期：2006-05-01 00:00:00

abstract：:The high level of protection elicited in rodents and primates by the radiation-attenuated schistosome vaccine gives hope that a human vaccine relying on equivalent mechanisms is feasible. In humans, a vaccine would be undoubtedly administered to previously or currently infected individuals. We have therefore used the ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Coulson PS,Kariuki TM

更新日期：2006-09-01 00:00:00

abstract：:Tungiasis is a parasitic skin disease widespread in resource-poor urban and rural communities in Brazil. Inhabitants of an urban slum in Northeast Brazil were examined for the presence of tungiasis lesions and followed-up twice a week for a period of three weeks. Each time the number, stages, and topographic localizat...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Feldmeier H,Kehr JD,Poggensee G,Heukelbach J

更新日期：2006-02-01 00:00:00

abstract：:Nontuberculous mycobacteria are ubiquitous and saprophytic organisms that have been implicated in a wide spectrum of diseases due to an increasing number of immunocompromised patients. The natural resistance of atypical mycobacteria to classical antituberculous drugs has encouraged research into new chemotherapeutic a...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Silva JL,Mesquita AR,Ximenes EA

更新日期：2009-07-01 00:00:00

abstract：:The objective of this study was to evaluate the feeding behavior of Triatoma vitticeps through the identification of its food sources and the characterization of the blood ingestion process. In addition, we aimed to verify if the saliva of this vector interferes with the perception of the host during the feedings by c...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Souza Rde C,Soares AC,Alves CL,Lorosa ES,Pereira MH,Diotaiuti L

更新日期：2011-02-01 00:00:00

abstract：:The sample consists of 226 skulls from the Atacameño cemetery of Coyo Oriente (639-910 AD), associated with the Tiwanaku period. The authors analyzed signs of acute trauma typically associated with violence, and the results were 12% of men and 9.9% of women displaying any type of lesion related to violence. In males, ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Lessa A,de Souza SM

更新日期：2006-12-05 00:00:00

abstract：:Schistosoma mansoni infections are associated with a strong Th2 cytokine response. Treatment of mice with IL-12 or anti-IL-2 or anti-IL-4 before i.v. injection of eggs increased IFN-gamma production and downregulated Th2 responses and pulmonary granuloma size. Conversely, anti-IFN-gamma antibody treatment increased Th...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cheever AW,Jankovic D,Yap GS,Kullberg MC,Sher A,Wynn TA

更新日期：1998-01-01 00:00:00

abstract：:A major advance in our understanding of the natural history of Schistosoma haematobium-related morbidity has come through the introduction of the portable ultrasound machines for non-invasive examination of the kidneys and bladder. With the use of generators or battery packs to supply power in non-clinical field setti...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： King CH

更新日期：2002-01-01 00:00:00

abstract：:This study was undertaken to investigate the prevalence of Mansonella ozzardi infection and to estimate the parasitic infection rate (PIR) in simuliid black flies in the municipality of Pauini, Amazonas, Brazil. We used thick blood films to examine 921 individuals in 35 riverine communities along the Pauini and Purus ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Medeiros JF,Py-Daniel V,Barbosa UC,Izzo TJ

更新日期：2009-02-01 00:00:00

abstract：:Protection against Fasciola hepatica in goats immunized with a synthetic recombinant antigen from Schistosoma mansoni fatty acid-binding protein 14 (rSm14) was investigated by assessing worm burdens, serum levels of hepatic enzymes, faecal egg count and hepatic damage, which was evaluated using gross and microscopic m...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Mendes RE,Zafra R,Pérez-Ecija RA,Buffoni L,Martínez-Moreno A,Tendler M,Pérez J

更新日期：2010-08-01 00:00:00

abstract：:This study had the objective of to analyze the demographic and bacteriologic data of 32 hospitalized newborns in an neonatal intensive care unit of a public maternity hospital in Rio de Janeiro city, Brazil, seized by Pseudomonas aeruginosa sepsis during a period ranged from July 1997 to July 1999, and to determine th...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Loureiro MM,de Moraes BA,Mendonca VL,Quadra MR,Pinheiro GS,Asensi MD

更新日期：2002-04-01 00:00:00