N-terminal amino acid sequences of the major outer membrane proteins from a Neisseria meningitidis group B strain isolated in Brazil.

Abstract:

:The four dominant outer membrane proteins (46, 38, 33 and 28 kDa) were detected by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) in a semi-purified preparation of vesicle membranes of a Neisseria meningitidis (N44/89, B:4:P1.15:P5.5,7) strain isolated in Brazil. The N-terminal amino acid sequence for the 46 kDa and 28 kDa proteins matched that reported by others for class 1 and 5 proteins respectively, whereas the sequence (25 amino acids) for the 38 kDa (class 3) protein was similar to class 1 meningococcal proteins. The sequence for the 33 kDa (class 4) was unique and not homologous to any known protein.

journal_name

Mem Inst Oswaldo Cruz

authors

De Simone SG,Soares SA,Souza AL,Danelli MG

doi

10.1590/s0074-02761996000100020

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

111-6

issue

1

eissn

0074-0276

issn

1678-8060

pii

S0074-02761996000100020

journal_volume

91

pub_type

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