Chromatin regulation in schistosomes and histone modifying enzymes as drug targets.

abstract：:As pyrethroids are presently the favored group of insecticides to control triatomines, we performed a series of bioassays to determine the intrinsic activity of some of the main compounds used in the control campaigns, against five of the main species of triatomines to be controlled. Comparing the insecticides it can ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Oliveira Filho AM

更新日期：1999-01-01 00:00:00

abstract：:Through its life cycle from the insect vector to mammalian hosts Trypanosoma cruzi has developed clever strategies to reach the intracellular milieu where it grows sheltered from the hosts' immune system. We have been interested in several aspects of in vitro interactions of different infective forms of the parasite w...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Mortara RA,Procópio DO,Barros HC,Verbisck NV,Andreoli WK,Silva RB,da Silva S

更新日期：1999-01-01 00:00:00

abstract：:Nontuberculous mycobacteria are ubiquitous and saprophytic organisms that have been implicated in a wide spectrum of diseases due to an increasing number of immunocompromised patients. The natural resistance of atypical mycobacteria to classical antituberculous drugs has encouraged research into new chemotherapeutic a...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Silva JL,Mesquita AR,Ximenes EA

更新日期：2009-07-01 00:00:00

abstract：:A massive and homogeneous amount of amastigote-like forms was detected in the stomodeal valve (SV) and the thoracic mid-gut (TMG) of Leishmania major-infected Phlebotomus papatasi, which received a second blood meal 13 to 21 days post-infection on healthy anaesthetized hamsters. After re-feeding, the infected sand fli...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Añez N,Tang Y,Rojas A,Crisante G,Killick-Kendrick M,Killick-Kendrick R

更新日期：2003-06-01 00:00:00

abstract：:While the influence of water in Helicobacter pylori culturability and membrane integrity has been extensively studied, there are little data concerning the effect of this environment on virulence properties. Therefore, we studied the culturability of water-exposed H. pylori and determined whether there was any relatio...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Guimarães NM,Azevedo NF,Vieira MJ,Figueiredo C

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Since the early 1990s, programs to control Chagas disease in South America have focused on eradicating domiciliary Triatoma infestans, the main vector. Seroprevalence studies of the chagasic infection are included as part of the vector control programs; they are essential to assess the impact of vector contr...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Russomando G,Cousiño B,Sanchez Z,Franco LX,Nara EM,Chena L,Martínez M,Galeano ME,Benitez L

更新日期：2017-05-01 00:00:00

abstract：:A simple and rapid method for differentiating the sibling species Biomphalaria tenagophila and Biomphalaria occidentalis by agarose gel electrophoresis (AGE) is described. Snail hemolymph is used as the test sample and the red coloration of the hemoglobin fraction permits visualization of the migration patterns withou...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Bailey JB,Michelson EH,Paraense WL

更新日期：1986-07-01 00:00:00

abstract：:Immunoblot analysis was used to investigate antigenic differences among clinical isolates of Leishmania amazonensis and their role in the etiology of the disease. Western blots of promastigote homogenates were analyzed with either monoclonal antibodies (MAbs) specific for the L. mexicana complex (M-4, M-6, M-9, and M-...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Leon LL,Machado GM,Barral A,de Carvalho-Paes LE,Grimaldi Júnior G

更新日期：1992-04-01 00:00:00

abstract：:A survey of the carrion fauna was made at two sites in Curitiba, State of Paraná, with the objective of describing the insects associated with carrion and setting up a preliminary data-base for medico-legal purposes in south Brazil. Vertebrate exclusion experiments were carried out in each season between 1994 and 1995...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Moura MO,de Carvalho CJ,Monteiro-Filho EL

更新日期：1997-03-01 00:00:00

abstract：:The black flies of the genus Inaequalium present a Neotropical distribution, with Panama at the northern limit, and the Argentinian pampas at the southern, but do not occur in the Central Amazon. This study offers a cladistic analysis establishing a hypothesis of relationships between the species of Inaequalium. A tot...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Strieder MN,Py-Daniel V

更新日期：2002-01-01 00:00:00

abstract：:In schistosomiasis, the host/parasite interaction remains not completely understood. Many questions related to the susceptibility of snails to infection by respective trematode still remain unanswered. The control of schistosomiasis requires a good understanding of the host/parasite association. In this work, the susc...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Abdel-Hamid AH,Rawi SM,Arafa AF

更新日期：2006-12-01 00:00:00

abstract：:The four dominant outer membrane proteins (46, 38, 33 and 28 kDa) were detected by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) in a semi-purified preparation of vesicle membranes of a Neisseria meningitidis (N44/89, B:4:P1.15:P5.5,7) strain isolated in Brazil. The N-terminal amino acid sequenc...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： De Simone SG,Soares SA,Souza AL,Danelli MG

更新日期：1996-01-01 00:00:00

abstract：:An increased plasma concentration of von Willebrand factor (vWF) is detected in individuals with many infectious diseases and is accepted as a marker of endothelium activation and prothrombotic condition. To determine whether ExoU, a Pseudomonas aeruginosa cytotoxin with proinflammatory activity, enhances the release ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Freitas C,Assis MC,Saliba AM,Morandi VM,Figueiredo CC,Pereira M,Plotkowski MC

更新日期：2012-09-01 00:00:00

abstract：:Distinct Toxoplasma gondii antigens were entrapped within liposomes and evaluated for their ability to protect Balb/c mice against congenital transmission: soluble tachyzoite antigen (L/STAg), soluble tissue cyst antigen (L/SCAg), soluble tachyzoite plus tissue cyst (L/STCAg) or purified 32kDa antigen of tachyzoite (L...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Elsaid MM,Martins MS,Frézard F,Braga EM,Vitor RW

更新日期：2001-01-01 00:00:00

abstract：:Sandfly prevalence in the Kani tribe settlements of Western Ghats in India was investigated. A total of 1,279 sandflies comprising 17 species was obtained. Sandfly abundance showed a negative correlation (r = -0.97, p = 0.003) with increase in altitudinal ranges from 0-1,000 m. When sandfly samples were grouped accord...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ranganathan S,Swaminathan S

更新日期：2015-04-01 00:00:00

abstract：:Infection of C3H/He mice with the Peruvian strain of Trypanosoma cruzi (Biodeme type I, Z2b), a macrophagotropic strain, determined severe parasitism of macrophages, necrosis of the spleen, and high host mortality. In the present study, pentoxifylline (PTX), an inhibitor of TNF-alpha was investigated on its action upo...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Andrade SG,Magalhães Ldos A,Pessina DH

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Cutaneous leishmaniasis (CL) generally presents with a single or several localised cutaneous ulcers without involvement of mucous membranes. Ulcerated lesions are susceptible to secondary contamination that may slow the healing process. OBJECTIVE:This study verified the influence of non-parasitic wound infe...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Antonio LF,Lyra MR,Saheki MN,Schubach AO,Miranda LFC,Madeira MF,Lourenço MCDS,Fagundes A,Ribeiro ÉADS,Barreto L,Pimentel MIF

更新日期：2017-09-01 00:00:00

abstract：:Cephalobium magdalensis n. sp. (Rhabditida: Diplogasteridae) found in Magdalena, Buenos Aires, and Cruznema lincolnensis n. sp. (Rhabditida: Rhabditidae) found in Lincoln, Buenos Aires, parasitizing the cricket Gryllodes laplatae (Orthoptera: Gryllidae) are described and illustrated. C. magdalensis n. sp. is character...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Reboredo GR,Camino NB

更新日期：1998-11-01 00:00:00

abstract：:Aedes albopictus was found in six of the 10 departments of Haiti and in 14 of the 35 communes surveyed. The survey found the larvae of Ae. albopictus in 13 different types of containers. Used tires and tins were by far the most common breeding sites used by this mosquito species. At the breeding sites, Ae. albopictus ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Fernández Mdel C,Jean YS,Callaba CA,López LS

更新日期：2012-03-01 00:00:00

abstract：:Previous investigations showed that Schistosoma mansoni infection aggravates protein malabsorption in undernourished mice and this can be reverted by administration of casein hydrolysate. The present study was undertaken to evaluate the effects of ingestion of casein hydrolysate for long periods. Albino Swiss mice wer...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ferreira HS,Coutinho EM,Nascimento GR,Carvalho MC

更新日期：1998-01-01 00:00:00

abstract：:Leptospirosis is a zoonotic disease caused by pathogenic spirochetes of the Leptospira genus. Vaccination with bacterins has severe limitations. Here, we evaluated the N-terminal region of the leptospiral immunoglobulin-like B protein (LigBrep) as a vaccine candidate against leptospirosis using immunisation strategies...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Forster KM,Hartwig DD,Oliveira TL,Bacelo KL,Schuch R,Amaral MG,Dellagostin OA

更新日期：2015-12-01 00:00:00

abstract：:Aspartyl proteases are a class of enzymes that include the yeast aspartyl proteases and secreted aspartyl protease (Sap) superfamilies. Several Sap superfamily members have been demonstrated or suggested as virulence factors in opportunistic pathogens of the genus Candida. Candida albicans, Candida tropicalis, Candida...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Parra-Ortega B,Cruz-Torres H,Villa-Tanaca L,Hernández-Rodríguez C

更新日期：2009-05-01 00:00:00

abstract：:In the Brazilian Amazon, American tegumentary leishmaniasis (ATL) is endemic and presents a wide spectrum of clinical manifestations due, in part, to the circulation of at least seven Leishmania species. Few reports of Leishmania (Viannia) naiffi infection suggest that its occurrence is uncommon and the reported cases...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Fagundes-Silva GA,Romero GA,Cupolillo E,Yamashita EP,Gomes-Silva A,Guerra JA,Da-Cruz AM

更新日期：2015-09-01 00:00:00

abstract：:Sand fly identification is complex because it depends on the expertise of the taxonomist. The females show subtle morphological differences and the occurrence of the species complexes are usual in this taxon. Therefore, a fragment of the cytochrome c oxidase subunit I (COI) gene is used for taxon barcoding to resolve ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Laurito M,Ontivero IM,Almirón WR

更新日期：2019-11-28 00:00:00

abstract：:St. Louis encephalitis virus (SLEV) and West Nile virus (WNV) present ecological and antigenic similarities and are responsible for serious human diseases. In addition, WNV is a significant pathogen in terms of equine health. The purpose of our study was to analyse the seroprevalence of SLEV and WNV in equine sera col...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Tauro L,Marino B,Diaz LA,Lucca E,Gallozo D,Spinsanti L,Contigiani M

更新日期：2012-06-01 00:00:00

abstract：:[This corrects the article doi: 10.1590/0074-02760180073]. ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors：

更新日期：2018-01-01 00:00:00

abstract：:Genomic DNA fragments from males of Psychodopygus wellcomei were isolated and shown to be useful as sensitive diagnostic probes for positively separating individuals of this species from those of Ps. complexus. These two members of the Ps. squamiventris series are found sympatrically in foci of cutaneous leishmaniasis...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Ready PD,Lainson R,Shaw JJ,Souza AA

更新日期：1991-01-01 00:00:00

abstract：:The preferred food items of the slugs Laevicaulis alte and the snails Achatina fulica were used to prepare 'poison baits' by injecting the pesticides 'Rogor' and 'Nuvan' to kill these mollusc pests. The 'poison baits' prepared with Trichosanthes dioica and Lycopersicum esculentum were accepted by 100% individuals of b...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Panigrahi A,Raut SK

更新日期：1993-04-01 00:00:00

abstract：:Granuloma size is the variable most frequently used to evaluate the immunopathogenesis of schistosome infections. However, hepatic fibrosis is at the least an equally relevant variable. Hepatic fibrosis and the size of circumoval granulomas are frequently dissociated in experimental murine Schistosoma mansoni and S. j...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Cheever AW

更新日期：1997-09-01 00:00:00

abstract：:In visceral leishmaniasis, phlebotomine vectors are targets for control measures. Understanding the ecosystem of the vectors is a prerequisite for creating these control measures. This study endeavours to delineate the suitable locations of Phlebotomus argentipes with relation to environmental characteristics between ...

journal_title：Memorias do Instituto Oswaldo Cruz

authors： Kesari S,Bhunia GS,Kumar V,Jeyaram A,Ranjan A,Das P

更新日期：2011-08-01 00:00:00