Abstract:
:To identify the best low level laser photobiomodulation application site at the same irradiation time to increase the viability of the skin flap in rats. Eighteen male rats (Rattus norvegicus: var. Albinus, Rodentia Mammalia) were randomly distributed into three groups (n = 6). Group I (GI) was submitted to simulated laser photobiomodulation; group II (GII) was submitted to laser photobiomodulation at three points in the flap cranial base, and group III (GIII) was submitted to laser photobiomodulation at 12 points distributed along the flap. All groups were irradiated with an Indium, Galium, Aluminum, and Phosphorus diode laser (InGaAlP), 660 nm, with 50 mW power, irradiated for a total time of 240 s in continuous emission mode. The treatment started immediately after performing the cranial base random skin flap (10 × 4 cm2 dimension) and reapplied every 24 h, with a total of five applications. The animals were euthanized after the evaluation of the percentage of necrosis area, and the material was collected for histological analysis on the seventh postoperative day. GII animals presented a statistically significant decrease for the necrosis area when compared to the other groups, and a statistically significant increase in the quantification of collagen when compared to the control. We did not observe a statistical difference between the TGFβ and FGF expression in the different groups evaluated. The application of laser photobiomodulation at three points of the flap cranial base was more effective than at 12 points regarding the reduction of necrosis area.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Martignago CCS,Tim CR,Assis L,Neves LMG,Bossini PS,Renno AC,Avo LRS,Liebano RE,Parizotto NAdoi
10.1007/s10103-018-2694-3subject
Has Abstractpub_date
2019-07-01 00:00:00pages
1041-1047issue
5eissn
0268-8921issn
1435-604Xpii
10.1007/s10103-018-2694-3journal_volume
34pub_type
杂志文章abstract::Despite the positive effects of low-level laser therapy (LLLT) on muscle fatigue before exercises using a single muscle group, the acute effects of LLLT on performance in cardiopulmonary exercise testing (CPET) are poorly understood. We aimed to assess the acute effects of LLLT on physiologic and electromyographic res...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
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abstract::Acneiform rash associated with epidermal growth factor receptor inhibitors frequently presents facial manifestations. The treatment modality for such lesions still needs to be elucidated. The aim of this original report was to evaluate the effectiveness of high-level laser therapy in reducing the severity of facial ac...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-011-1029-4
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abstract::Inflammation of synovial membrane and degeneration of articular cartilage in osteoarthritis (OA) lead to major changes in joint space width (JSW) and biochemical components such as collagen-II telopeptide (CTX-II) and matrix metallo protineases (MMP-3, 8, and 13). Low-level laser therapy (LLLT) is thought to have an a...
journal_title:Lasers in medical science
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abstract::This study aims to evaluate whether optical coherence tomography (OCT) using both the surface and the endoluminal technique is feasible to investigate the locations and degree of encrustation process in clinically used ureteral stents. After removal from patients, 14 polyurethane JJ stents were investigated. A fresh J...
journal_title:Lasers in medical science
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journal_title:Lasers in medical science
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journal_title:Lasers in medical science
pub_type: 杂志文章
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-019-02766-9
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abstract::In 30 patients with periodontitis, a total of 278 teeth exhibiting bleeding on probing, subgingival calculus, and a probing depth between 3-6 mm were examined. For each participant, two treatment types were alternatively applied on the contralateral quadrants: scaling and root planing (SRP) as control, and SRP followe...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-010-0799-4
更新日期:2011-07-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
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更新日期:2015-01-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-008-0564-0
更新日期:2009-05-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-014-1560-1
更新日期:2014-09-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-013-1350-1
更新日期:2015-02-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-018-2488-7
更新日期:2018-07-01 00:00:00
abstract::Endometriosis is a chronic disease affecting mainly women of the reproductive age. Its most common manifestations include impaired fecundity, pelvic pain, and dyschezia. Laparoscopic removal of endometriotic foci remains to be the gold standard for the treatment of endometriosis. More effective techniques of endoscopi...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-014-1630-4
更新日期:2015-01-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-019-02931-0
更新日期:2020-04-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章
doi:10.1007/s10103-018-2531-8
更新日期:2018-11-01 00:00:00
abstract::There is concern that the delicate fibres and cylindrical diffuser tips used for intraluminal PDT of blood vessels might break during the treatment. We have developed and tested a simple system to monitor for fibre breakage during PDT. Light from the laser is passed through a beam expander, then a beam splitter, and t...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-003-0270-x
更新日期:2003-01-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-007-0489-z
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journal_title:Lasers in medical science
pub_type: 杂志文章
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journal_title:Lasers in medical science
pub_type: 杂志文章
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journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-010-0804-y
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-012-1213-1
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-011-0953-7
更新日期:2012-03-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章,评审
doi:10.1007/s10103-019-02947-6
更新日期:2020-08-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章,评审
doi:10.1007/s10103-006-0420-z
更新日期:2007-06-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章,评审
doi:10.1007/s10103-011-0921-2
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2398-0
更新日期:2018-04-01 00:00:00
abstract::Photodynamic rejuvenation therapy (PDRT) is a growing field in cosmetic dermatology. In this study, different sources of light (a yellow laser, a red laser and ultraviolet A (UVA) lamps) were used to activate a second-generation photosensitiser, hypericin. Uptake of hypericin was monitored over 24 h and efficacy of PD...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-012-1115-2
更新日期:2013-02-01 00:00:00
abstract::In spinal cord injury (SCI), inflammation is a major mediator of damage and loss of function and is regulated primarily by the bone marrow-derived macrophages (BMDMs). Photobiomodulation (PBM) or low-level light stimulation is known to have anti-inflammatory effects and has previously been used in the treatment of SCI...
journal_title:Lasers in medical science
pub_type: 杂志文章
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更新日期:2020-09-01 00:00:00