Abstract：
:This in vitro study evaluated the role of photobiomodulation therapy (PBMT) on viability and migration of human dental pulp stem cells (hDPSCs) and its association to epigenetic mechanisms such as histone acetylation. The hDPSCs were characterized and assigned into control and PBMT groups. For the PBMT, five laser irradiations at 6-h intervals were performed using a continuous-wave InGaAlP diode laser. Viability (MTT), migration (scratch), and histone acetylation H3 (H3K9ac immunofluorescence) were evaluated immediately after the last irradiation. PBMT significantly increased the viability (P = 0.004). Also, PBMT group showed significantly increased migration of cells in the wound compared to the control in 6 h (P = 0.002), 12 h (P = 0.014) and 18 h (P = 0.083) being faster than the control, which only finished the process at 24 h. PBMT induced epigenetic modifications in hDPSC due to increased histone acetylation (P = 0.001). PBMT increased viability and migration of hDPSCs, which are related with the upregulation of histone acetylation and could be considered a promising adjuvant therapy for regenerative endodontic treatment.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Zaccara IM,Mestieri LB,Pilar EFS,Moreira MS,Grecca FS,Martins MD,Kopper PMPdoi
10.1007/s10103-019-02931-0subject
Has Abstractpub_date
2020-04-01 00:00:00pages
741-749issue
3eissn
0268-8921issn
1435-604Xpii
10.1007/s10103-019-02931-0journal_volume
35pub_type
杂志文章abstract：:This retrospective case-control study aimed to compare 30 versus 40 W power of CO2 laser for the therapy of genitourinary syndrome of menopause (GSM). Postmenopausal women with severe intensity of dyspareunia and dryness were eligible to be included in this study. Primary outcomes were dyspareunia and dryness. Seconda...
journal_title：Lasers in medical science
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abstract：:Scars from self-inflicted wounds, referred to as "hesitation marks," are usually linear, flat, poorly oriented, white in color, and often located on the forearm. Many patients do not undergo treatment for these due to limited available modalities. The aim of this study was to evaluate the efficacy and safety of the pi...
journal_title：Lasers in medical science
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abstract：:Zirconia has been regarded as a promising material for dental implants, and Nd:YAG laser treatment has been proposed as a potential strategy to improve its bioactivity. The main aim of the present study was to evaluate the in vitro behavior of human fetal osteoblasts in contact with laser-textured zirconia implant sur...
journal_title：Lasers in medical science
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abstract：:The aims of this study were to evaluate the effects of Photogem®-mediated photosensitization on rat palatal mucosa and the biodistribution of the photosensitizer in this tissue. A solution of Photogem® (500 or 1000 mg/l) was applied to the palatal mucosa for 30 min and the exposure time to blue LED (460 nm) was 20 min...
journal_title：Lasers in medical science
pub_type： 杂志文章
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journal_title：Lasers in medical science
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journal_title：Lasers in medical science
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journal_title：Lasers in medical science
pub_type： 杂志文章,评审
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journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：Lasers in medical science
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journal_title：Lasers in medical science
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更新日期：2020-07-23 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章
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journal_title：Lasers in medical science
pub_type： 杂志文章
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journal_title：Lasers in medical science
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journal_title：Lasers in medical science
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更新日期：2006-04-01 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章
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更新日期：2010-01-01 00:00:00
abstract：:To determine the relation between retinal microstructural changes and the response to 577-nm subthreshold micropulse laser (SML) treatment in chronic central serous chorioretinopathy (cCSC). This retrospective study included 39 eyes of 39 patients with cCSC, treated with the 577-nm SML. The eyes were evaluated in thre...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03225-6
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abstract：:In this study, the impact of two-dimensional (2D) and three-dimensional (3D) vision on laparoscopic performance of novice surgeons is examined. Twenty-five novice surgeons were directed to complete four basic tasks from European Training in Basic Laparoscopic Urological Skills (E-BLUS) with both 2D and 3D systems in a...
journal_title：Lasers in medical science
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abstract：:A new outpatient non-surgical method using Er:YAG laser for snoring has been demonstrated. The aim of this systematic review and meta-analysis was to investigate the effects of this treatment on snoring. Relevant 1548 articles were searched from various databases from 1 January 2000 to September 2018 including PubMed,...
journal_title：Lasers in medical science
pub_type： 杂志文章,meta分析
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journal_title：Lasers in medical science
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journal_title：Lasers in medical science
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journal_title：Lasers in medical science
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更新日期：2010-03-01 00:00:00
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journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
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journal_title：Lasers in medical science
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journal_title：Lasers in medical science
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journal_title：Lasers in medical science
pub_type： 杂志文章,meta分析,评审
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abstract：:Epithelial cells play an important role in reparative events. Therefore, therapies that can stimulate the proliferation and metabolism of these cells could accelerate the healing process. To evaluate the effects of low-level laser therapy (LLLT), human keratinocytes were irradiated with an InGaAsP diode laser prototyp...
journal_title：Lasers in medical science
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