Abstract:
:This study analyzed the effects of photobiomodulation (PBM) with low-level laser therapy on nociceptive behavior and neuronal activity in the trigeminal nucleus after experimental unilateral temporomandibular joint (TMJ) disc injury. The animals were divided into 4 groups (n = 10 each): group 1, surgical injury of the articular disc and PBM; group 2, sham-operated subjected to PBM; group 3, surgical injury of the articular disc; and group 4, control (Naïve). Ten sessions of PBM were performed using GaAs laser with a wavelength of 904 nm, power of 75 W pico, average power of 0.043 W, area of the beam of 0.13 cm2, duration of the pulses of 60 nseg (in the frequency of 9500 Hz), energy density of 5.95 J/cm2, energy per point of 0.7 J, and power density of 333.8 mW/cm2, and the irradiation was done for 18 s per point. Neuropathic symptoms were evaluated using the von Frey test. Trigeminal ganglion samples underwent immunoblotting to examine the expression of substance P, vanilloid transient potential receptor of subtype-1 (TRPV-1), and peptide related to the calcitonin gene (CGRP). There was a total decrease in pain sensitivity after the second session of PBM in operated animals, and this decrease remains until the last session. There was a significant decrease in the expression of SP, TRPV-1, and CGRP after PBM. Photobiomodulation therapy was effective in reducing nociceptive behavior and trigeminal nucleus neuronal activity after TMJ disc injury.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
de Freitas Rodrigues A,de Oliveira Martins D,Chacur M,Luz JGCdoi
10.1007/s10103-019-02842-0subject
Has Abstractpub_date
2020-03-01 00:00:00pages
447-453issue
2eissn
0268-8921issn
1435-604Xpii
10.1007/s10103-019-02842-0journal_volume
35pub_type
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journal_title:Lasers in medical science
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journal_title:Lasers in medical science
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journal_title:Lasers in medical science
pub_type: 杂志文章,已发布勘误
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abstract::Acupuncture is a form of traditional Chinese medicine that has developed over thousands of years. We studied the effects of laser puncture, needle acupuncture, and light stimulation on cerebral blood flow in 15 healthy volunteers (mean age 25.0±1.9 years, 5 female, 10 male) with non-invasive transcranial Doppler sonog...
journal_title:Lasers in medical science
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journal_title:Lasers in medical science
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journal_title:Lasers in medical science
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journal_title:Lasers in medical science
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