Abstract:
:To evaluate the efficacy of short-term subthreshold micropulse yellow laser photocoagulation (SMYLP) on eyes with diabetic macular edema (DME) with different central foveal thicknesses (CFT). Eighty eyes of 40 patients who had previously undergone ranibizumab treatment for DME and who subsequently had recurrent macular edema were included to the study. The study subjects were divided into four groups according to their initial CFT values (group 1, 250-300 μm; group 2, 301-400 μm; group 3, > 401 μm; group 4, 250-300 μm untreated control subjects). Patients were treated with SMYLP for one session and followed for 6 months. All patients underwent complete ophthalmologic evaluation. The alteration from baseline in CFT and the best corrected visual acuity (BCVA) were measured. Patients with a pretreatment CFT ≤ 300 μm experienced the statistically significant reduction in CFT and gain in BCVA at 2 months (p < 0.05), whereas patients with baseline CFT > 300 μm experienced no significant change (p > 0.05). Hyperautofluorescence lesions, that were not previously described, were detected in fundus autofluorescence imaging in the early period after SYMLP laser and these lesions were regressed with time. Our study indicates that the SYMLP provides a statistically significant improvement in BCVA and a reduction in CFT in the patients with a pretreatment CFT of 300 μm or less in DME and can be safe and effective in mild DME treatment.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Citirik Mdoi
10.1007/s10103-018-2672-9subject
Has Abstractpub_date
2019-07-01 00:00:00pages
907-912issue
5eissn
0268-8921issn
1435-604Xpii
10.1007/s10103-018-2672-9journal_volume
34pub_type
杂志文章abstract::Gingival melanin hyperpigmentation is an esthetic concern for many individuals. In this study, we compared the standard surgical removal method with two different Er,Cr:YSGG laser settings in order to find the best treatment method. In 33 dental arches, the following three treatment groups were comparatively evaluated...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-018-2501-1
更新日期:2018-11-01 00:00:00
abstract::The erbium:YSGG and erbium:YAG lasers are used for tissue ablation in dermatology, dentistry and ophthalmology. The purpose of this study was to compare germanium oxide and sapphire optical fibres for transmission of sufficient Q-switched erbium laser pulse energies for potential use in both soft and hard tissue ablat...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-004-0316-8
更新日期:2004-01-01 00:00:00
abstract::A rabbit model of endophthalmitis was established to evaluate the antiinflammatory effect of low-level laser therapy (LLLT) as an adjunct to treatment for Staphylococcus epidermidis endophthalmitis. Rabbits were randomly divided into three groups to receive intravitreal injections into their left eye: group A received...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-011-0991-1
更新日期:2012-05-01 00:00:00
abstract::We evaluated functional and morphological changes after trans-tympanic laser application using several different powers of photobiomodulation (PBM). The left (L) ears of 17 rats were irradiated for 30 min daily over 14 days using a power density of 909.1 (group A, 5040 J), 1136.4 (group B, 6300 J), and 1363.6 (group C...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-015-1851-1
更新日期:2016-02-01 00:00:00
abstract::The aim of the present study was to assess, by means of Raman spectroscopy, the repair of complete surgical tibial fractures fixed with wire osteosynthesis (WO) treated or not with infrared laser (λ780 nm) or infrared light emitting diode (LED) (λ850 ± 10 nm) lights, 142.8 J/cm2 per treatment, associated or not to the...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-018-2508-7
更新日期:2018-11-01 00:00:00
abstract::Recurrent herpes labialis is a worldwide life-long oral health problem that remains unsolved. It affects approximately one third of the world population and causes frequent pain and discomfort episodes, as well as social restriction due to its compromise of esthetic features. In addition, the available antiviral drugs...
journal_title:Lasers in medical science
pub_type: 杂志文章,评审
doi:10.1007/s10103-013-1311-8
更新日期:2014-07-01 00:00:00
abstract::In an in vitro study, the effect of light polarization on the efficiency of 5-aminolaevulinic acid (ALA) photodynamic therapy (PDT) of basal cell carcinoma (BCC) was investigated. Three states of light polarization (non-polarized, linearly polarized, and circularly polarized) were considered. Cells were exposed to gre...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2369-5
更新日期:2018-02-01 00:00:00
abstract::Low-energy laser irradiation (Ga-Al-As semiconductor laser, output 50 mW) was applied to rat osteoclast precursor cells for 1, 3, 6, or 10 min at 24-h intervals during the culture period. The number of tartrate-resistant acid phosphatase positive multinucleate cells was increased by approximately 1.3-fold in the 3- an...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-005-0368-4
更新日期:2006-04-01 00:00:00
abstract::The purpose of this study is to evaluate microtensile bond strength (μTBS) of an etch-and-rinse adhesive to enamel and dentin after treatment with Er:YAG laser using different pulse durations. Extracted human molars were flattened to obtain enamel or dentin surfaces. The enamel specimens (E) were divided into nine gro...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-010-0830-9
更新日期:2012-01-01 00:00:00
abstract::Skin represents an interface between internal and external environment; it protects human body by regulating the water loss and the maintenance of body temperature, defending against irritant and pathogen agents, and against physical, chemical, and UV damage. It provides to essential physiological functions, such as t...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-018-2635-1
更新日期:2019-04-01 00:00:00
abstract::Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of infections in humans. Photodynamic therapy using blue light (450 nm) could possibly be used to reduce MRSA on different human tissue surfaces without killing the human cells. It could be less harmful than 300-400 nm light or common disinfectan...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-019-02774-9
更新日期:2019-12-01 00:00:00
abstract::The purpose of this study is twofold: (1) to determine the feasibility of optical coherence tomography (OCT) to differentiate normal and diseased tissue of the neck region intraoperatively and (2) to evaluate how accurately a cohort of test subjects can identify various tissue types when shown a sample set of OCT imag...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-020-03024-z
更新日期:2020-04-27 00:00:00
abstract::Although the application of Q-switched lasers on nevus of Ota (OTA) is well demonstrated, debates about clinical option between Q-switched alexandrite laser (QSA) and Q-switched Nd:YAG laser (QSNY) still remain. This systematic review and meta-analysis estimated the overall successful rate of OTA pigment clearance and...
journal_title:Lasers in medical science
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s10103-016-1885-z
更新日期:2016-04-01 00:00:00
abstract::The authors tested the diagnostic potential of the portable autofluorescence optical system that was developed in the preoperative evaluation of resection margins, and thus of the resection line safety in patients with low-positioned colorectal carcinoma. A total of 217 spectral measurements of the fluorescence proper...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-010-0847-0
更新日期:2011-05-01 00:00:00
abstract::Nonablative skin rejuvenation using laser, intense pulsed lights (IPLs), or radiofrequency techniques are becoming increasingly popular. In this paper, a novel protocol that integrates IPL sessions, low intense light and vitamin C, low-weight hyaluronic acid, betaglucan dermal injection versus IPL photorejuvenation as...
journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s10103-007-0456-8
更新日期:2008-04-01 00:00:00
abstract::For better evaluation of the efficacy of low-level laser therapy in treating painful diabetic neuropathy and in protecting nerve fiber damage, we conducted a study with type 1 diabetic rats induced by streptozotocin. It is well known that diabetic peripheral neuropathy is the leading cause of pain in those individuals...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-016-2140-3
更新日期:2017-04-01 00:00:00
abstract::The objective of this study was to evaluate the microbiological and clinical outcomes following nonsurgical treatment by either scaling and root planing, combination of Nd:YAG and Er:YAG lasers, or by Er:YAG laser treatment alone. The study involved 60 patients with generalized chronic periodontitis, randomly assigned...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-018-2491-z
更新日期:2018-09-01 00:00:00
abstract::The aim of this in vitro study was to assess the effect of Er:YAG laser surface treatment on the tensile bond strength of a sealant in permanent teeth. A total of 30 sound third molars were selected and embedded in cold-cure acrylic resin. The enamel surfaces were flattened by a grinding. The teeth were randomly divid...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-010-0869-7
更新日期:2012-03-01 00:00:00
abstract::Dermatosis papulosa nigra (DPN) is a common condition of pigmented skin. Whilst lesions are benign, they may be symptomatic or cosmetically disfiguring. Ablative lasers have previously been reported as a useful therapeutic modality in DPN. We report the largest case series to date of patients with DPN ablated with the...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-016-1906-y
更新日期:2016-04-01 00:00:00
abstract::The goal of this study was to assess the ablation, coagulation, and carbonization characteristics of the holmium:YAG (Ho:YAG) laser and thulium fiber lasers (TFL). The Ho:YAG laser (100 W av.power), the quasi-continuous (QCW) TFL (120 W av.power), and the SuperPulsed (SP) TFL (50 W av.power) were compared on a non-fro...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-020-03189-7
更新日期:2020-11-11 00:00:00
abstract::Two-photon excited fluorescence (TPEF) microscopy, based on signal from cells, can provide detailed information on tissue architecture and cellular morphology in unstained histological sections to generate subcellular-resolution images from tissue directly. In this paper, we used TPEF microscopy to image microstructur...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-014-1652-y
更新日期:2015-01-01 00:00:00
abstract::Candida albicans is an opportunistic pathogen commensal in the oral cavity, vagina, and healthy skin. Common therapeutic options for fungal infections are topical or systemic antifungal drugs. Recently, in cutaneous pathologies, lasers and light-based treatments have emerged showing few contraindications and minimal s...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2407-3
更新日期:2018-07-01 00:00:00
abstract::Oral mucositis (OM) and radiodermatitis (RD) are serious side effects of radiotherapy (RT), often leading to its suspension, need for analgesics, and enteral/parenteral nutrition. Laser therapy is becoming a recommended treatment option. This prospective study aimed at demonstrating the beneficial effect of class IV l...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-015-1857-8
更新日期:2016-04-01 00:00:00
abstract::For chronic rhinitis that is refractory to medical therapy, surgical intervention such as endoscopic vidian neurectomy (VN) can be used to control the intractable symptoms. Lasers can contribute to minimizing the invasiveness of ENT surgery. The aim of this retrospective study is to compare in patients who underwent d...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2330-7
更新日期:2017-12-01 00:00:00
abstract::Photobiomodulation is a treatment that has been widely used in neurotrauma and neurodegenerative diseases. In the present study, low-level laser therapy was administered to patients with spinal cord injury. Twenty-five individuals were divided into two groups: placebo photobiomodulation plus physiotherapy and active p...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-018-2447-3
更新日期:2018-05-01 00:00:00
abstract::The aim of the present study was to evaluate the success rate of failed implants re-implanted after surface treatment with CO2 laser. Despite the widespread use of dental implants, there are many incidents of failures. It is believed that lasers can be applied to decontaminate the implant surface without damaging the ...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-016-1921-z
更新日期:2016-07-01 00:00:00
abstract::To evaluate the efficacy and safety of holmium laser enucleation of prostate (HoLEP) for treating urinary retention in patients with advanced prostate cancer. Thirty-eight cases of advanced prostate cancer with urinary retention were enrolled in this retrospective study. All the 38 patients were treated with CAB as a ...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-019-02913-2
更新日期:2020-08-01 00:00:00
abstract::From the very first reports describing the method of action of phototherapy, the effects have been considered to be the result of photochemical and photophysical interactions between the absorbed photons and tissue and not related to secondary changes in tissue or skin temperature. However, thermal effects have been r...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-015-1755-0
更新日期:2015-07-01 00:00:00
abstract::We describe the diversity of indications for laser hair removal (LHR) therapy and compare our experience with the literature. Patients' case notes referred to the Birmingham Regional Skin Laser Centre between 2003 and 2011 for laser hair removal, with indications other than hirsutism, were reviewed retrospectively. Th...
journal_title:Lasers in medical science
pub_type: 杂志文章,评审
doi:10.1007/s10103-013-1464-5
更新日期:2015-01-01 00:00:00
abstract::Patients with pain avoid movements, leading to a gradual impairment of their physical condition and functionality. In this context, the use of ultrasound (US) and low-level laser therapy (LLLT) show promising results for nonpharmacological and noninvasive treatment. The aim of this study was evaluated the synergistic ...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-014-1659-4
更新日期:2015-01-01 00:00:00