Abstract:
:Recurrent herpes labialis is a worldwide life-long oral health problem that remains unsolved. It affects approximately one third of the world population and causes frequent pain and discomfort episodes, as well as social restriction due to its compromise of esthetic features. In addition, the available antiviral drugs have not been successful in completely eliminating the virus and its recurrence. Currently, different kinds of laser treatment and different protocols have been proposed for the management of recurrent herpes labialis. Therefore, the aim of the present article was to review the literature regarding the effects of laser irradiation on recurrent herpes labialis and to identify the indications and most successful clinical protocols. The literature was searched with the aim of identifying the effects on healing time, pain relief, duration of viral shedding, viral inactivation, and interval of recurrence. According to the literature, none of the laser treatment modalities is able to completely eliminate the virus and its recurrence. However, laser phototherapy appears to strongly decrease pain and the interval of recurrences without causing any side effects. Photodynamic therapy can be helpful in reducing viral titer in the vesicle phase, and high-power lasers may be useful to drain vesicles. The main advantages of the laser treatment appear to be the absence of side effects and drug interactions, which are especially helpful for older and immunocompromised patients. Although these results indicate a potential beneficial use for lasers in the management of recurrent herpes labialis, they are based on limited published clinical trials and case reports. The literature still lacks double-blind controlled clinical trials verifying these effects and such trials should be the focus of future research.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
de Paula Eduardo C,Aranha AC,Simões A,Bello-Silva MS,Ramalho KM,Esteves-Oliveira M,de Freitas PM,Marotti J,Tunér Jdoi
10.1007/s10103-013-1311-8subject
Has Abstractpub_date
2014-07-01 00:00:00pages
1517-29issue
4eissn
0268-8921issn
1435-604Xjournal_volume
29pub_type
杂志文章,评审abstract::The purpose of this study is to evaluate microtensile bond strength (μTBS) of an etch-and-rinse adhesive to enamel and dentin after treatment with Er:YAG laser using different pulse durations. Extracted human molars were flattened to obtain enamel or dentin surfaces. The enamel specimens (E) were divided into nine gro...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-010-0830-9
更新日期:2012-01-01 00:00:00
abstract::There is concern that the delicate fibres and cylindrical diffuser tips used for intraluminal PDT of blood vessels might break during the treatment. We have developed and tested a simple system to monitor for fibre breakage during PDT. Light from the laser is passed through a beam expander, then a beam splitter, and t...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-003-0270-x
更新日期:2003-01-01 00:00:00
abstract::This ablation rate study has been carried out with a fibre-deliverable, 308 nm, XeCl laser, producing long pulses of 200 ns as opposed to the usual 10-20 ns. This in-depth study aimed to evaluate the ablation rates for this longer pulse length. The effects on the ablation depth of dentine, enamel, soft tissue and bone...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-004-0315-9
更新日期:2004-01-01 00:00:00
abstract::To evaluate the efficacy and safety of holmium laser enucleation of prostate (HoLEP) for treating urinary retention in patients with advanced prostate cancer. Thirty-eight cases of advanced prostate cancer with urinary retention were enrolled in this retrospective study. All the 38 patients were treated with CAB as a ...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-019-02913-2
更新日期:2020-08-01 00:00:00
abstract::Recent studies have shown that direct laser metal sintering (DLMS) produces structures with complex geometry and consequently that allow better osteoconductive properties. The aim of this patient report was to evaluate the early bone response to DLMS implant surface retrieved from human jaws. Four experimental DLMS im...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-010-0831-8
更新日期:2011-01-01 00:00:00
abstract::To evaluate the efficacy of laser fibrotomy in patients with oral submucous fibrosis (OSMF) and also to correlate the habit variables causing OSMF. Thirty patients diagnosed clinically and histopathologically with OSMF were included in the study. Laser fibrotomy was done under local anesthesia using Zolar diode laser ...
journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章
doi:10.1007/s10103-018-2531-8
更新日期:2018-11-01 00:00:00
abstract::Our previous in vitro study has shown that toluidine blue (TB)-mediated lethal photosensitization of periodontal pathogens (PPs) from periodontal patients is possible. The purpose of this study was to investigate whether TB-mediated photosensitization exerted damaging effects on periodontal tissues in mice. Twenty-fou...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-007-0513-3
更新日期:2009-03-01 00:00:00
abstract::Low-level red laser (LLRL)-tissue interactions have a wide range of medical applications and are garnering increased attention. Although the positive effects of low-level laser therapy (LLLT) have frequently been reported and enhanced collagen accumulation has been identified as one of the most important mechanisms in...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-015-1823-5
更新日期:2015-12-01 00:00:00
abstract::This review aimed to identify the efficacy of low-level laser therapy (LLLT) in the management of orthodontic pain. This systematic review and meta-analysis was carried out in accordance with Cochrane Handbook and the PRISMA statement. An extensive literature search for RCTs, quasi-RCTs, and CCTs was performed through...
journal_title:Lasers in medical science
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s10103-012-1196-y
更新日期:2013-11-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-005-0328-z
更新日期:2005-01-01 00:00:00
abstract::Osteoarthritis (OA) triggers increased levels of inflammatory markers, including prostaglandin (PG) E2 and proinflammatory cytokines. The elevation of cytokine levels is closely associated with increased articular tissue degeneration. Thus, the use of combination therapies may presumably be able to enhance the effects...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-016-2091-8
更新日期:2017-01-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-012-1251-8
更新日期:2013-11-01 00:00:00
abstract::The potential of laser-induced fluorescence (LIF) spectroscopy for the characterization of different stages of dental caries using 404-nm diode laser excitation was investigated. In vitro spectra from 16 sound, 10 noncavitated carious and 10 cavitated carious molar teeth were recorded on a miniature fibre-optic spectr...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-010-0771-3
更新日期:2011-05-01 00:00:00
abstract::In this study, the impact of two-dimensional (2D) and three-dimensional (3D) vision on laparoscopic performance of novice surgeons is examined. Twenty-five novice surgeons were directed to complete four basic tasks from European Training in Basic Laparoscopic Urological Skills (E-BLUS) with both 2D and 3D systems in a...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-015-1739-0
更新日期:2015-05-01 00:00:00
abstract::This study aimed to investigate the influence of low-power 830 nm gallium-aluminium-arsenide (GaAlAs) laser [continuous wave (CW) 40 mW and fluence 4 J/cm(2), with total energy density of 16 J/cm(2)] on the healing of human infra-bony defects treated with bioactive glass graft material. Twenty patients with chronic pe...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-008-0576-9
更新日期:2009-05-01 00:00:00
abstract::Skin flaps are still a matter of concern among surgeons, as failures can occur leading to flap necrosis. However, low-level laser irradiation has been reported as an effective tool to improve the viability of ischemic flaps, yet its mechanisms of action remain unclear. We investigated the effect of low-level laser irr...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-011-1011-1
更新日期:2012-05-01 00:00:00
abstract::Recent studies have demonstrated the beneficial effect of low-power lasers and polarized light on wound healing, inflammation, and the treatment of rheumatologic and neurologic disorders. The overall effect of laser irradiation treatment is still controversial due to the lack of studies on the biochemical mechanisms a...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2398-0
更新日期:2018-04-01 00:00:00
abstract::Patients with pain avoid movements, leading to a gradual impairment of their physical condition and functionality. In this context, the use of ultrasound (US) and low-level laser therapy (LLLT) show promising results for nonpharmacological and noninvasive treatment. The aim of this study was evaluated the synergistic ...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-014-1659-4
更新日期:2015-01-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-008-0595-6
更新日期:2009-09-01 00:00:00
abstract::Antimicrobial photodynamic therapy (APDT) combined with endodontic treatment has been recognized as an alternative approach to complement conventional root canal disinfection methods on bacterial biofilms. We developed an in vitro model of bioluminescent Candida albicans biofilm inside curved dental root canals and i...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-014-1629-x
更新日期:2015-08-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
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更新日期:2015-08-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章
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更新日期:2017-08-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章
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更新日期:2017-11-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章,评审
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更新日期:2020-08-19 00:00:00
abstract::In order to design and manufacture a reliable biomedical sensor, sensitive tests have to be performed. This is of superlative importance as it has to be used for the general public. Keeping this into account, the test mechanism of such an extremely sensitive sensor is being done that involves exhaustive protocols rega...
journal_title:Lasers in medical science
pub_type: 杂志文章
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更新日期:2020-09-01 00:00:00
abstract::A retrospective study was conducted to investigate the incidence of reported adverse responses after epilatory laser treatment to control the growth of facial hair in patients with polycystic ovary syndrome. Forty-eight patients received a median of 6 (range 2-11) treatments with an Aesculap ruby laser during a 704 da...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-007-0451-0
更新日期:2008-01-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-012-1057-8
更新日期:2013-02-01 00:00:00
abstract::Low-level visible light irradiation was found to stimulate proliferation potential of various types of cells in vitro. Stem cells in general are of significance for implantation in regenerative medicine. The aim of the present study was to investigate the effect of low-level light irradiation on the proliferation of m...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-012-1207-z
更新日期:2013-07-01 00:00:00
abstract::The aims of this study were to evaluate the effects of Photogem®-mediated photosensitization on rat palatal mucosa and the biodistribution of the photosensitizer in this tissue. A solution of Photogem® (500 or 1000 mg/l) was applied to the palatal mucosa for 30 min and the exposure time to blue LED (460 nm) was 20 min...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-011-0909-y
更新日期:2012-03-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章
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更新日期:2020-07-07 00:00:00