Abstract:
:Low-level visible light irradiation was found to stimulate proliferation potential of various types of cells in vitro. Stem cells in general are of significance for implantation in regenerative medicine. The aim of the present study was to investigate the effect of low-level light irradiation on the proliferation of mesenchymal stem cells (MSCs). MSCs were isolated from the bone marrow, and light irradiation was applied at energy densities of 2.4, 4.8, and 7.2 J/cm(2). Illumination of the MSCs resulted in almost twofold increase in cell number as compared to controls. Elevated reactive oxygen species and nitric oxide production was also observed in MSCs cultures following illumination with broadband visible light. The present study clearly demonstrates the ability of broadband visible light illumination to promote proliferation of MSCs in vitro. These results may have an important impact on wound healing.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Lipovsky A,Oron U,Gedanken A,Lubart Rdoi
10.1007/s10103-012-1207-zsubject
Has Abstractpub_date
2013-07-01 00:00:00pages
1113-7issue
4eissn
0268-8921issn
1435-604Xjournal_volume
28pub_type
杂志文章abstract::Most of the widely used scales to evaluate scars are subjective relying on clinical observations. There is a growing need to find out a noninvasive objective tool for this purpose. The study is aimed at evaluating the value of the high-resolution ultrasound in the assessment of the scars when compared with a clinical ...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-019-02830-4
更新日期:2020-03-01 00:00:00
abstract::This study compares sensitivity reduction after dental restoration with and without prior diode laser (DL) irradiation for cervical dentine hypersensitivity (CDH) from non-carious cervical lesions (NCCLs) unresponsive to desensitizing agents. Eighty-eight teeth of 28 subjects (21 females; age 23-64 years), with CDH fr...
journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章
doi:10.1007/s10103-016-2087-4
更新日期:2017-01-01 00:00:00
abstract::Photodynamic therapy (PDT) with photosensitizer is one of the promising modalities for cancer treatment. For clinical use of PDT, screening process should be preceded to enhance sensitivity to PDT. Thus, we investigated a molecular biomarker to determine the sensitivity to pheophorbide a (Pa)-PDT in immortalized human...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-013-1350-1
更新日期:2015-02-01 00:00:00
abstract::Knee osteoarthritis (KOA) is a common degenerative disease in which several treatments and treatment associations have been investigated. This review analyzed the efficacy of the association of photobiomodulation therapy (PBMT) and exercises for people with KOA in randomized controlled clinical trials. PubMed, Scopus,...
journal_title:Lasers in medical science
pub_type: 杂志文章,评审
doi:10.1007/s10103-020-03223-8
更新日期:2021-01-03 00:00:00
abstract::Retinal development involves a complex coordination of events that may be affected by premature delivery, leading to retinopathy of prematurity (ROP), a potential blinding childhood disease. The avascular retina drives further disease progression, with laser ablation reducing unfavorable anatomic outcomes as well as m...
journal_title:Lasers in medical science
pub_type: 杂志文章,评审
doi:10.1007/s10103-011-1021-z
更新日期:2013-02-01 00:00:00
abstract:PURPOSE:Acne scarring represents a common problem that negatively impacts patients' quality of life. Different types of treatments are currently available for this dermatological condition. This study evaluates the efficacy of a new 675-nm laser source system on acne scars with the use of established parameters that gu...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-020-03063-6
更新日期:2021-02-01 00:00:00
abstract::The objective of this study was to evaluate the microbiological and clinical outcomes following nonsurgical treatment by either scaling and root planing, combination of Nd:YAG and Er:YAG lasers, or by Er:YAG laser treatment alone. The study involved 60 patients with generalized chronic periodontitis, randomly assigned...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-018-2491-z
更新日期:2018-09-01 00:00:00
abstract::We evaluated functional and morphological changes after trans-tympanic laser application using several different powers of photobiomodulation (PBM). The left (L) ears of 17 rats were irradiated for 30 min daily over 14 days using a power density of 909.1 (group A, 5040 J), 1136.4 (group B, 6300 J), and 1363.6 (group C...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-015-1851-1
更新日期:2016-02-01 00:00:00
abstract::The objective of this study was to evaluate the safety and efficacy of flexible ureteroscopy (FURS) and holmium:YAG laser lithotripsy for the treatment of upper urinary tract stones in patients on active oral anticoagulants. The records of 1081 patients who underwent flexible ureteroscopic holmium:YAG (Ho:YAG) laser l...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2289-4
更新日期:2017-09-01 00:00:00
abstract::We aimed to evaluate the effectiveness of temperature-controlled laser soldering for repair of large perforated corneas in a porcine model. Eight Yorkshire pigs aged 6 months underwent 6-mm-deep 180° crescent-shaped trephination of the central corneas. Right corneal injuries were repaired by placement of 47 % bovine a...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-015-1737-2
更新日期:2015-05-01 00:00:00
abstract::Laser acupuncture is a modality of low-level light therapy used as an alternative to needling for the past three decades. Although it has proved effective for the treatment of various conditions, the mechanisms underlying its effects are not fully understood. To contribute to this understanding, this study was designe...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-012-1260-7
更新日期:2013-09-01 00:00:00
abstract::A disrupted wound repair process often leads to the development of chronic wounds, and pose a major physical, social and economic inconvenience on patients and the public health sector. Chronic wounds are a common complication seen in diabetes mellitus (DM), and often the severity necessitates amputation of the lower ...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-020-03041-y
更新日期:2020-06-01 00:00:00
abstract::The aim of this study was to evaluate the effect of cavity preparation with Er:YAG laser on dentin adjacent to restorations submitted to cariogenic challenge in situ, by subsuperficial microhardness analysis. Bovine incisors were sectioned, flattened, and polished, resulting in 40 dentin slabs. The slabs were randomly...
journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章
doi:10.1007/s10103-016-2136-z
更新日期:2017-02-01 00:00:00
abstract::Burn scars are known for their tendency to worsen with hypertrophy and contracture, causing esthetic and functional problems. The objective is to analyze the effectiveness of low-level laser therapy on post-burn hypertrophic scar tissue in children. A randomized controlled study included 15 children, ranging from 2 to...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-018-2572-z
更新日期:2018-12-01 00:00:00
abstract::Laser therapy is able to modulate cell metabolism and accelerate the repair of fracture. Little attention has been given to the effect of laser on bone with osteopenia or osteoporosis. The purpose of our study was to verify the effect of laser therapy in combination with bisphosphonate on osteopenic bone structure. Th...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-008-0568-9
更新日期:2009-05-01 00:00:00
abstract::Various therapies for the treatment of sprains have emerged as advances occur in biomedical engineering and photobiology. Therapy with coherent and non-coherent light is a treatment modality for various musculoskeletal injuries. The main certified phototherapy benefits are the reduction of nociceptive processes and th...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-018-2460-6
更新日期:2018-07-01 00:00:00
abstract::We evaluated the acute electrophysiological effects of low-energy pulsed laser irradiation on isolated frog sciatic nerve measured by extracellular recording technique. A pulsed gallium-arsenide (GaAs) laser (wavelength: 904 nm, pulse duration 220 ns, peak power per pulse: 27W, spot size: 0.28 cm(2), total applied ene...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-002-8268-3
更新日期:2002-01-01 00:00:00
abstract::The aim of the present study was to investigate laser-fluorescence effects on the root surface. The possibility of detecting subgingival calculus should be evaluated to control complete calculus removal after scaling and root planing. Twenty freshly extracted human teeth, partially covered with calculus on the root su...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-002-0241-7
更新日期:2003-01-01 00:00:00
abstract::This review aimed to identify the efficacy of low-level laser therapy (LLLT) in the management of orthodontic pain. This systematic review and meta-analysis was carried out in accordance with Cochrane Handbook and the PRISMA statement. An extensive literature search for RCTs, quasi-RCTs, and CCTs was performed through...
journal_title:Lasers in medical science
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s10103-012-1196-y
更新日期:2013-11-01 00:00:00
abstract::Topical anaesthetic cream (TAC) is commonly used as a pre-treatment of ablative fractional resurfacing (AFR) laser. Most of anaesthetic cream contains distilled water as major component. Therefore, pre-operative TAC may interfere the photothermal reaction in the skin treated with fractional carbon-dioxide (FCO2) laser...
journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章
doi:10.1007/s10103-016-2112-7
更新日期:2017-02-01 00:00:00
abstract::Bactericidal and detoxification effects of diode laser (DL) have been reported in periodontal treatment. The objective of this study was investigating the additional effect of DL with nonsurgical periodontal treatment on the red complex bacteria in type 2 diabetes mellitus (DM) patients with chronic periodontitis (CP)...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-020-02997-1
更新日期:2020-08-01 00:00:00
abstract::Minimal hepatic encephalopathy (MHE) has been shown to affect daily functioning, quality of life, driving and overall mortality. However, little is known about treating or diagnosing early impairments involved in MHE. We studied one of its precipitating factors, portal hypertension. The purpose was to evaluate an enha...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-016-2042-4
更新日期:2016-11-01 00:00:00
abstract::The aim of this study was to compare the effects of Nd:YAG, Er:YAG, and diode lasers on the morphology and permeability of root canal walls. The three laser wavelengths mentioned interact differently with dentin and therefore it is possible that the permeability changes caused will determine different indications duri...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-010-0775-z
更新日期:2010-09-01 00:00:00
abstract::Primary hepatocellular carcinoma (HCC) and colon carcinoma are two of the most common clinical malignancies along with high morbidity and mortality. As low-power laser irradiation (LPLI) can induce cytotoxicity or cell apoptosis on several types of hyperplasia, LPLI may be a potential alternative treatment for gastroe...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-019-02869-3
更新日期:2020-04-01 00:00:00
abstract::The aim of this study was to verify the maximum number of repetitions, fatigue index, blood lactate concentration ([Lac]), and cardiac autonomic responses after LED irradiation (LEDI) in the ipsilateral and contralateral limb. Twelve male subjects (22.0 ± 3.86 years; weight 82.94 ± 12.58 kg; height 1.77 ± 0.05 m), phy...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-017-2391-7
更新日期:2018-02-01 00:00:00
abstract::Photodynamic therapy (PDT) has been used to inhibit intimal hyperplasia in injured arteries. Because of the limited tissue penetration of visible light, an endovascular light source with a guided wire is often required for effective treatment. Indocyanine green (ICG), a near-infrared (NIR) photosensitizer, has been us...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-018-2488-7
更新日期:2018-07-01 00:00:00
abstract::The potential of laser-induced fluorescence (LIF) spectroscopy for the characterization of different stages of dental caries using 404-nm diode laser excitation was investigated. In vitro spectra from 16 sound, 10 noncavitated carious and 10 cavitated carious molar teeth were recorded on a miniature fibre-optic spectr...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-010-0771-3
更新日期:2011-05-01 00:00:00
abstract::Laser micromachining with ultrashort pulses has shown great promise for clean, safe surgical treatment of bone tissue. However, comparisons of performance and development of "best practice" have been hampered by the difficulty of comparing results across a wide variety of experimental approaches and under surgically i...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-019-02899-x
更新日期:2020-08-01 00:00:00
abstract::Corrosiveness of enamel surfaces of Smartbleach, Opus White, Opalescense Xtra Boost and a gel containing titanium dioxide (TiO(2)) particles, activated either by a frequency doubled neodymium: yttrium-aluminum-garnet (Nd:YAG) laser (532 nm) or a diode laser (810 nm) was evaluated by environmental scanning electron mic...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-008-0567-x
更新日期:2009-05-01 00:00:00
abstract::The aim of this study was to evaluate the degree of conversion (DC) and to identify the viscoelastic properties: storage modulus (E'), loss modulus (E"), tangent delta (tan δ), and glass transition temperature (T g ) of a microhybrid resin-composite light-activated by three different protocols. A Filtek Z250 (3 M ESPE...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-014-1572-x
更新日期:2015-05-01 00:00:00