Abstract：
:This review aimed to identify the efficacy of low-level laser therapy (LLLT) in the management of orthodontic pain. This systematic review and meta-analysis was carried out in accordance with Cochrane Handbook and the PRISMA statement. An extensive literature search for RCTs, quasi-RCTs, and CCTs was performed through CENTRAL, PubMed, Embase, Medline, CNKI, and CBM up to October 2011. Risk of bias assessment was performed via referring to the Cochrane tool for risk of bias assessment. Meta-analysis was implemented using Review Manager 5.1. As a result, four RCTs, two quasi-RCTs, and two CCTs were selected from 152 relevant studies, including 641 patients from six countries. The meta-analysis demonstrated that 24% risk of incidence of pain was reduced by LLLT (RR = 0.76, 95% CI range 0.63-0.92, P = 0.006). In addition, compared to the control group, LLLT brought forward "the most painful day" (MD = -0.42, 95% CI range -0.74- -0.10, P = 0.009). Furthermore, the LLLT group also implied a trend of earlier end of pain compared with the control group (MD = -1.37, 95% CI range -3.37-0.64, P = 0.18) and the pseudo-laser group (MD = -1.04, 95% CI range -4.22-2.15, P = 0.52). However, because of the methodological shortcomings and risk of bias of included trials, LLLT was proved with limited evidence in delaying pain onset and reducing pain intensity. In the future, larger and better-designed RCTs will be required to provide clearer recommendations.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
He WL,Li CJ,Liu ZP,Sun JF,Hu ZA,Yin X,Zou SJdoi
10.1007/s10103-012-1196-ysubject
Has Abstractpub_date
2013-11-01 00:00:00pages
1581-9issue
6eissn
0268-8921issn
1435-604Xjournal_volume
28pub_type
杂志文章,meta分析,评审abstract：:Liquid-assisted hard tissue ablation by infrared lasers has extensive clinical application. However, detailed studies are still needed to explore the underlying mechanism. In the present study, the dynamic process of bubble evolution induced by Ho:YAG laser under water without and with bone tissue at different thickne...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-1931-x
更新日期：2016-07-01 00:00:00
abstract：:The optical properties of the skin (absorption coefficient, scattering coefficient, refractive index) may serve to characterize the skin and are important for correct light dosimetry in many optical diagnostic procedures and laser treatments especially photodynamic therapy and laser therapy. We determined in vivo the ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-009-0725-9
更新日期：2010-03-01 00:00:00
abstract：:This study aimed to evaluate the surface changes caused in zirconia by different surface treatments and the influence of the surface treatment and cement selection on bonding to zirconia under aging. Sintered zirconia specimens were divided into five groups (n = 31) based on the surface treatment, namely, control, air...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1221-1
更新日期：2014-01-01 00:00:00
abstract：:The use of the CO(2) laser in the management of oral dysplastic lesions has become a more common practice. Very few studies have evaluated recurrence, residual disease malignant transformation, and overall outcome in patients undergoing such a procedure. In this prospective study, a total of 123 oral dysplastic lesion...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-011-0916-z
更新日期：2012-01-01 00:00:00
abstract：:Previous studies have been suggested that photodynamic therapy (PDT) can be used as an adjuvant treatment for denture stomatitis. In this study, we evaluated the effects of multiple sessions of PDT on Candida glabrata biofilms in specimens of polymerized acrylic resin formed after 5 days. Subsequently, four applicatio...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2147-4
更新日期：2017-04-01 00:00:00
abstract：:The objective of this study was to evaluate the microbiological and clinical outcomes following nonsurgical treatment by either scaling and root planing, combination of Nd:YAG and Er:YAG lasers, or by Er:YAG laser treatment alone. The study involved 60 patients with generalized chronic periodontitis, randomly assigned...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-018-2491-z
更新日期：2018-09-01 00:00:00
abstract：:Burn scars are known for their tendency to worsen with hypertrophy and contracture, causing esthetic and functional problems. The objective is to analyze the effectiveness of low-level laser therapy on post-burn hypertrophic scar tissue in children. A randomized controlled study included 15 children, ranging from 2 to...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-018-2572-z
更新日期：2018-12-01 00:00:00
abstract：:The in vivo photodynamic activities of four poly(ethylene glycol) (PEG) conjugates of the photosensitiser 5,10,15,20-tetrakis-(m-hydroxyphenyl)chlorin (mTHPC, temoporfin, Foscan(®)) were compared with that of mTHPC over a range of drug-light intervals using acute tumour necrosis and skeletal muscles swelling in a mous...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s101030050019
更新日期：1999-03-01 00:00:00
abstract：:We report the use of spectral domain polarization sensitive optical coherence tomography for ex-vivo imaging of human oral mandibular tissue samples. Our results show that compared to the changes observed in the epithelium thickness and the decay constant of A-scan intensity profile, a much larger degree of change was...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-2096-3
更新日期：2017-01-01 00:00:00
abstract：:The present work evaluated the effects of LED light irradiation on the healing of the navels of neonatal dairy calves. Fifty-seven neonatal calves were divided into two groups. Animals had their umbilical stumps immersed in 10% iodine tincture for 60 s, and this process was repeated every 24 h for three consecutive da...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2283-x
更新日期：2017-09-01 00:00:00
abstract：:The Nd:YAG laser efficacy associated with conventional treatment for bacterial reduction has been investigated throughout literature. The purpose of this study was to evaluate the bacterial reduction after Nd:YAG laser irradiation associated with scaling and root planning in class II furcation defects in patients with...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s10103-007-0482-6
更新日期：2008-10-01 00:00:00
abstract：:We evaluated functional and morphological changes after trans-tympanic laser application using several different powers of photobiomodulation (PBM). The left (L) ears of 17 rats were irradiated for 30 min daily over 14 days using a power density of 909.1 (group A, 5040 J), 1136.4 (group B, 6300 J), and 1363.6 (group C...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-015-1851-1
更新日期：2016-02-01 00:00:00
abstract：:Oxygen consumption at the targeted site has a significant effect on dosimetry in photodynamic therapy (PDT). However, oxygen consumption in PDT using a pulsed laser as a light source has not been clarified. We therefore investigated the dependence of cytotoxicity on the oxygen consumption and the photosensitizer photo...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-004-0288-8
更新日期：2004-01-01 00:00:00
abstract：:Acne vulgaris is one of the most common dermatologic disorders encountered in everyday practice. Treatment options for this often psychologically scarring disease are numerous and, for many individuals, provide relief from the disorder. However, factors such as antibiotic resistance and slow onset of action from many ...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-006-0420-z
更新日期：2007-06-01 00:00:00
abstract：:This retrospective case-control study aimed to compare 30 versus 40 W power of CO2 laser for the therapy of genitourinary syndrome of menopause (GSM). Postmenopausal women with severe intensity of dyspareunia and dryness were eligible to be included in this study. Primary outcomes were dyspareunia and dryness. Seconda...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2293-8
更新日期：2017-11-01 00:00:00
abstract：:A rabbit model of endophthalmitis was established to evaluate the antiinflammatory effect of low-level laser therapy (LLLT) as an adjunct to treatment for Staphylococcus epidermidis endophthalmitis. Rabbits were randomly divided into three groups to receive intravitreal injections into their left eye: group A received...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0991-1
更新日期：2012-05-01 00:00:00
abstract：:Epithelial cells play an important role in reparative events. Therefore, therapies that can stimulate the proliferation and metabolism of these cells could accelerate the healing process. To evaluate the effects of low-level laser therapy (LLLT), human keratinocytes were irradiated with an InGaAsP diode laser prototyp...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1057-8
更新日期：2013-02-01 00:00:00
abstract：:The present study aimed to evaluate in vitro whether the low-level laser (LLL) delivering fractionated total energy (multiple irradiation) or single irradiation stimulates regeneration-associated events (viability and proliferation) in stem cells from human exfoliated deciduous teeth (SHED). Cells received LLL irradia...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02836-y
更新日期：2019-12-01 00:00:00
abstract：:Although the application of Q-switched lasers on nevus of Ota (OTA) is well demonstrated, debates about clinical option between Q-switched alexandrite laser (QSA) and Q-switched Nd:YAG laser (QSNY) still remain. This systematic review and meta-analysis estimated the overall successful rate of OTA pigment clearance and...
journal_title：Lasers in medical science
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s10103-016-1885-z
更新日期：2016-04-01 00:00:00
abstract：:The aim of this study was to evaluate the effect of cavity preparation with Er:YAG laser on dentin adjacent to restorations submitted to cariogenic challenge in situ, by subsuperficial microhardness analysis. Bovine incisors were sectioned, flattened, and polished, resulting in 40 dentin slabs. The slabs were randomly...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-016-2136-z
更新日期：2017-02-01 00:00:00
abstract：:Crohn's disease is a chronic relapsing and remitting inflammatory condition which affects any part of the gastrointestinal tract. In the oro-facial region, patients can present peri-oral swellings which results in severe facial disfigurement. To date, assessing the degree of facial changes and evaluation of treatment ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1286-5
更新日期：2014-05-01 00:00:00
abstract：:Recent studies with phototherapy have shown positive results in enhancement of performance and improvement of recovery when applied before exercise. However, several factors still remain unknown such as therapeutic windows, optimal treatment parameters, and effects of combination of different light sources (laser and ...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-014-1611-7
更新日期：2014-11-01 00:00:00
abstract：:We evaluate the safety, efficacy, and oncological outcomes of early palliative photoselective vaporization of the prostate (PVP) by GreenLight high-performance system (HPS) 120-W laser in patients with acute urinary retention (AUR) induced by advanced prostate cancer (PCa). A total of 39 advanced PCa patients with AUR...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1252-7
更新日期：2013-09-01 00:00:00
abstract：:Antibiotics and photodynamic therapy (PDT) are widely employed in curing acne. However, antibiotics as an effective treatment would lead to bacterial resistance and severe side effects. In this study, we aimed to develop a novel TBO hydrogel, which could prolong the retention time of photosensitizer (TBO) at the lesio...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02727-2
更新日期：2019-10-01 00:00:00
abstract：:Various therapies for the treatment of sprains have emerged as advances occur in biomedical engineering and photobiology. Therapy with coherent and non-coherent light is a treatment modality for various musculoskeletal injuries. The main certified phototherapy benefits are the reduction of nociceptive processes and th...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-018-2460-6
更新日期：2018-07-01 00:00:00
abstract：:The optical properties of hemoglobin could indicate the degree of hemolysis. We aimed to utilize this to develop a real-time blood damage monitoring device for cardiopulmonary bypass (CPB) systems. The real-time blood damage monitoring device comprised a near-infrared spectroscopy optical module with a fiber spectrome...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03094-z
更新日期：2020-07-10 00:00:00
abstract：:The objective of this study was to describe the dynamics of water heating carried out by continuous laser radiation with wavelengths 1.47, 1.55, and 1.94 μm with different types of fibers used for endovenous laser coagulation. The study was conducted in water using high-speed surveying of the heating process through t...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03184-y
更新日期：2020-11-07 00:00:00
abstract：:Induction of matrix synthesis by low-level laser has been demonstrated extensively. However, the question of dose- or power intensity-dependency is under-investigated. To address this issue we chose human osteoblast cell cultures and measured their alkaline phosphatase (ALP) activity after laser irradiation. The cell ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0511-5
更新日期：2008-10-01 00:00:00
abstract：:Fungal infection of nails, onychomycosis, is predominantly caused by Trichophyton rubrum. This infection is an important public health concern due to its persistent nature and high recurrence rates. Alternative treatments are urgently required. One such alternative is phototherapy involving the action of photothermal ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1287-4
更新日期：2014-01-01 00:00:00
abstract：:In an in vitro study, the effect of light polarization on the efficiency of 5-aminolaevulinic acid (ALA) photodynamic therapy (PDT) of basal cell carcinoma (BCC) was investigated. Three states of light polarization (non-polarized, linearly polarized, and circularly polarized) were considered. Cells were exposed to gre...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2369-5
更新日期：2018-02-01 00:00:00
