Abstract：
:This retrospective case-control study aimed to compare 30 versus 40 W power of CO2 laser for the therapy of genitourinary syndrome of menopause (GSM). Postmenopausal women with severe intensity of dyspareunia and dryness were eligible to be included in this study. Primary outcomes were dyspareunia and dryness. Secondary outcomes were itching/burning, dysuria, frequency and urgency, Female Sexual Function Index (FSFI), vaginal maturation value (VMV), and Vaginal Health Index Score (VHIS). One laser therapy was applied every month for 3 months. Outcomes were evaluated at baseline and 1 month following the 3rd therapy. Fifty (25 per group) women were included in this study. In the 30-W group, mean improvement of dyspareunia, dryness, itching/burning, FSFI, VMV, and VHIS was 6.1 ± 1.7, 6.0 ± 1.9, 5.9 ± 2.0, 16.6 ± 6.7, 29.9 ± 13.0, and 11.0 ± 2.9, respectively (within group comparisons all p < 0.001). In the 40-W group, mean improvement of dyspareunia, dryness, itching/burning, FSFI, VMV, and VHIS was 6.1 ± 1.7, 6.5 ± 2.0, 5.2 ± 2.5, 14.8 ± 7.1, 25.0 ± 13.4, and 10.5 ± 4.1, respectively (within-group comparisons, all p ≤ 0.001). Comparison between 30 and 40 W revealed that mean improvement or presence of all GSM symptoms and clinical signs was not statistically significant different. CO2 laser therapy may improve GSM symptoms and clinical signs. This improvement did not seem to associate to power of 30 or 40 W.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Pitsouni E,Grigoriadis T,Falagas M,Tsiveleka A,Salvatore S,Athanasiou Sdoi
10.1007/s10103-017-2293-8subject
Has Abstractpub_date
2017-11-01 00:00:00pages
1865-1872issue
8eissn
0268-8921issn
1435-604Xpii
10.1007/s10103-017-2293-8journal_volume
32pub_type
杂志文章abstract：:Dermatosis papulosa nigra (DPN) is a common condition of pigmented skin. Whilst lesions are benign, they may be symptomatic or cosmetically disfiguring. Ablative lasers have previously been reported as a useful therapeutic modality in DPN. We report the largest case series to date of patients with DPN ablated with the...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-1906-y
更新日期：2016-04-01 00:00:00
abstract：:The aim of the present study was to investigate the influence of low-level red (660 nm) and infrared (780 nm) laser with four different radiance exposures on human umbilical vein endothelial cells (HUVECs) in vitro. HUVECs (1.5 × 104) were incubated in 96-well culture plates. The cells were maintained in M199 medium s...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03016-z
更新日期：2021-02-01 00:00:00
abstract：:The aim of the present study was to investigate laser-fluorescence effects on the root surface. The possibility of detecting subgingival calculus should be evaluated to control complete calculus removal after scaling and root planing. Twenty freshly extracted human teeth, partially covered with calculus on the root su...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-002-0241-7
更新日期：2003-01-01 00:00:00
abstract：:The purpose of this study is to determine the effectiveness of endoscopic diode laser therapy in patients presenting rectal bleeding due to chronic radiation proctitis (CRP). A retrospective analysis of CRP patients who underwent diode laser therapy in a single institution between 2010 and 2016 was carried out. The pa...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2323-6
更新日期：2018-01-01 00:00:00
abstract：:In order to design and manufacture a reliable biomedical sensor, sensitive tests have to be performed. This is of superlative importance as it has to be used for the general public. Keeping this into account, the test mechanism of such an extremely sensitive sensor is being done that involves exhaustive protocols rega...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02945-8
更新日期：2020-09-01 00:00:00
abstract：:Laser acupuncture is a modality of low-level light therapy used as an alternative to needling for the past three decades. Although it has proved effective for the treatment of various conditions, the mechanisms underlying its effects are not fully understood. To contribute to this understanding, this study was designe...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1260-7
更新日期：2013-09-01 00:00:00
abstract：:To evaluate the efficacy of laser fibrotomy in patients with oral submucous fibrosis (OSMF) and also to correlate the habit variables causing OSMF. Thirty patients diagnosed clinically and histopathologically with OSMF were included in the study. Laser fibrotomy was done under local anesthesia using Zolar diode laser ...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-018-2531-8
更新日期：2018-11-01 00:00:00
abstract：:Most of the widely used scales to evaluate scars are subjective relying on clinical observations. There is a growing need to find out a noninvasive objective tool for this purpose. The study is aimed at evaluating the value of the high-resolution ultrasound in the assessment of the scars when compared with a clinical ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02830-4
更新日期：2020-03-01 00:00:00
abstract：:Wound healing is a very complex process, some phases of which have only recently been explained. Magnetic and electromagnetic fields can modulate this process in a non-thermal way. The aim of this research was to compare the influence of constant and pulsed electromagnetic fields and low-level laser therapy (LLLT) on ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0564-0
更新日期：2009-05-01 00:00:00
abstract：:The molecular changes in gene expression following ablative laser treatment of skin lesions, such as atrophic scars and UV-damaged skin, are not completely understood. A standardized in vitro model of human skin, to study the effects of laser treatment on human skin, has been recently developed. Therefore, the aim of ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2175-0
更新日期：2017-05-01 00:00:00
abstract：:Endometriosis is a chronic disease affecting mainly women of the reproductive age. Its most common manifestations include impaired fecundity, pelvic pain, and dyschezia. Laparoscopic removal of endometriotic foci remains to be the gold standard for the treatment of endometriosis. More effective techniques of endoscopi...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-014-1630-4
更新日期：2015-01-01 00:00:00
abstract：:Low-level laser therapy (LLLT) has proved to have biostimulating effects on tissues over which they are applied, therefore accelerating the healing process. Most studies in implantology were focused on a reduction of the duration of osseointegration. There exist few articles analyzing the potential effects of these th...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-015-1860-0
更新日期：2016-02-01 00:00:00
abstract：:Bisphosphonate-related osteonecrosis of the jaw is a well-known potential side effect of long-term bisphosphonate therapy; the primary objective of the treatment should be to improve patient quality of life through pain and infection management, to prevent the development of new lesions, and to slow disease progressio...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-016-1929-4
更新日期：2016-08-01 00:00:00
abstract：:A growing number of laboratory and clinical studies over the past 10 years have shown that low-level laser stimulation (633 or 670 nm) at extremely low power densities (about 0.15 mW/cm(2)), when administered through a particular emission mode, is capable of eliciting significant biological effects. Studies on cell cu...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-010-0837-2
更新日期：2011-01-01 00:00:00
abstract：:Low-level visible light irradiation was found to stimulate proliferation potential of various types of cells in vitro. Stem cells in general are of significance for implantation in regenerative medicine. The aim of the present study was to investigate the effect of low-level light irradiation on the proliferation of m...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1207-z
更新日期：2013-07-01 00:00:00
abstract：:Low-energy laser irradiation (Ga-Al-As semiconductor laser, output 50 mW) was applied to rat osteoclast precursor cells for 1, 3, 6, or 10 min at 24-h intervals during the culture period. The number of tartrate-resistant acid phosphatase positive multinucleate cells was increased by approximately 1.3-fold in the 3- an...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-005-0368-4
更新日期：2006-04-01 00:00:00
abstract：:The aim of this study was to investigate the effects of low-level laser (LLL) irradiation on the turnover of fibronectin and collagen type I in periodontal tissue during tooth movement in rats by immunohistochemistry. Thirty male Sprague-Dawley rats aged 15 weeks were assigned to either an experimental group (n = 15) ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0585-8
更新日期：2010-01-01 00:00:00
abstract：:Oral lichen planus (OLP) is an inflammatory disease that can be painful, mainly in the atrophic and erosive forms. Numerous drugs have been used with dissimilar results, but most treatments are empirical. However, to date, the most commonly employed and useful agents for the treatment of OLP are topical corticosteroid...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-013-1313-6
更新日期：2014-01-01 00:00:00
abstract：:The objective of this study was to determine the efficacy and safety of a novel method of facial rejuvenation using a 2940-nm erbium:YAG laser with Spatially Modulated Ablation™. A pilot study was performed in 16 women with moderate to severe signs of facial aging relative to chronological age, who underwent two treat...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-016-2010-z
更新日期：2016-09-01 00:00:00
abstract：:A nevus is described as a benign, often pigmented, skin growth that can be congenital or acquired. Different types of nevi are located at different depths within the skin. Traditional treatments for nevi include topical treatments, dermabrasion, and excision, which are generally ineffective, invasive, and often result...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-014-1697-y
更新日期：2015-09-01 00:00:00
abstract：:We assess the long-term effect of pulsed high-intensity laser therapy (HILT) in the treatment of the post-mastectomy pain syndrome (PMPS). A total of 61 women participated in this study (30 in the laser group and 31 in the placebo laser group), with a mean age of 53.56 ± 1.11 years. Patients who were randomly assigned...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-015-1780-z
更新日期：2015-08-01 00:00:00
abstract：:The aim of the present study was to evaluate the success rate of failed implants re-implanted after surface treatment with CO2 laser. Despite the widespread use of dental implants, there are many incidents of failures. It is believed that lasers can be applied to decontaminate the implant surface without damaging the ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-1921-z
更新日期：2016-07-01 00:00:00
abstract：:The aim of this study was to compare the concentration of mast cells (MCs) in the healing process of incisions. Thirty rats were submitted to six linear incisions each, performed in the dorsal skin by carbon dioxide (CO(2)) and diode lasers, electrocautery and conventional scalpel. The animals were euthanized at inter...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0616-5
更新日期：2009-07-01 00:00:00
abstract：:Preclinical studies have shown that photodynamic therapy (PDT) enhances immune responses. To examine the role of the direct effects of PDT in liver cancer with regard to enhancement of the antitumor response, we injected PDT-generated H22 liver cancer cell lysate (as a tumor vaccine) intradermally into Kunming mice. I...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0609-4
更新日期：2009-07-01 00:00:00
abstract：:Excimer laser recanalisation of in-stent restenosis may be a viable modality for improving coronary patency. However, the presence of arterial stents modifies the thermal properties of the irradiated area and may alter temperature patterns generated during ablation. The goal of this study was to evaluate, in vitro, te...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/pl00011348
更新日期：2001-01-01 00:00:00
abstract：:Low-level red laser (LLRL)-tissue interactions have a wide range of medical applications and are garnering increased attention. Although the positive effects of low-level laser therapy (LLLT) have frequently been reported and enhanced collagen accumulation has been identified as one of the most important mechanisms in...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-015-1823-5
更新日期：2015-12-01 00:00:00
abstract：:It is well known that laser-assisted hatching (LAH) is the most popular and ideal embryo hatching technology, but the relevance to pregnancy outcomes of cryopreserved-thawed embryo transfer (ET) is controversial. The purpose of this meta-analysis was to evaluate the effects of LAH on pregnancy outcomes of cryopreserve...
journal_title：Lasers in medical science
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s10103-017-2372-x
更新日期：2018-04-01 00:00:00
abstract：:Physical stimulation of body surface points is known to affect various organ functions. In traditional Chinese medicine, so-called acupoints were defined. These points can be physically stimulated to effectively treat various diseases. Here we describe for the first time the effect of CO(2) laser stimulation at the ac...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0973-3
更新日期：2012-03-01 00:00:00
abstract：:The purpose of this article was to analyze the photobiomodulator role of low-level laser therapy (LLLT) on the skeletal muscle remodeling following cryoinjury in rats, focusing the types I and III collagen proteins. Laser phototherapy has been employed to stimulate repair in different tissues. However, its role in ske...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0951-9
更新日期：2011-11-01 00:00:00
abstract：:The aim of this study was to determine whether it is safe to use photo-activated disinfection (PAD) during root canal treatment without heating the periodontal tissues. Root canals of 30 freshly extracted single-rooted teeth were prepared using ProFiles up to size ISO 40 and then filled with photo-sensitiser: tolonium...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0526-y
更新日期：2009-01-01 00:00:00
