Abstract：
:The objective of this study was to determine the efficacy and safety of a novel method of facial rejuvenation using a 2940-nm erbium:YAG laser with Spatially Modulated Ablation™. A pilot study was performed in 16 women with moderate to severe signs of facial aging relative to chronological age, who underwent two treatment sessions with an Er:YAG laser coupled to the RecoSMA™ technology (Linline, Minsk, Belarus). The whole face was treated in all patients. Clinical efficacy, tolerance, adverse effects, complications, and histological changes due to the treatment were evaluated. Clinical photographs and biopsies were taken before treatment and 3 months after the second treatment session. All patients completed the study and presented no significant complications. Histological changes in the epidermis and dermis as a result of treatment were found. Fine lines, wrinkles, and overall facial aging improved significantly (p < 0.0001). The mean reduction of fine lines and wrinkles was 59 % (r = 40-75 %). The mean improvement of overall facial aging was 74 % (r = 55-90 %). After showing the patients the comparative photographs before and after treatment, 75 % of women stated that they were satisfied or very satisfied and would recommend the treatment. Preliminary results show an excellent safety/efficacy profile for this novel technology, which, based on observed results, can be considered to have advantages over other methods of facial rejuvenation with lasers.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Trelles MA,Khomchenko V,Alcolea JM,Martínez-Carpio PAdoi
10.1007/s10103-016-2010-zsubject
Has Abstractpub_date
2016-09-01 00:00:00pages
1465-71issue
7eissn
0268-8921issn
1435-604Xpii
10.1007/s10103-016-2010-zjournal_volume
31pub_type
临床试验,杂志文章abstract：:Laser acupuncture is a modality of low-level light therapy used as an alternative to needling for the past three decades. Although it has proved effective for the treatment of various conditions, the mechanisms underlying its effects are not fully understood. To contribute to this understanding, this study was designe...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1260-7
更新日期：2013-09-01 00:00:00
abstract：:This study aimed to investigate the influence of low-power gallium-aluminium-arsenide (GaAlAs) laser [830 nm, continuous wave (CW), 40 mW and fluence 4 J/cm(2)] on the healing of surgically created bone defects in rats treated with bioactive glass graft material. Surgical bone defects were created in the mandibles of ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0590-y
更新日期：2009-07-01 00:00:00
abstract：:The present study aimed to evaluate in vitro whether the low-level laser (LLL) delivering fractionated total energy (multiple irradiation) or single irradiation stimulates regeneration-associated events (viability and proliferation) in stem cells from human exfoliated deciduous teeth (SHED). Cells received LLL irradia...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02836-y
更新日期：2019-12-01 00:00:00
abstract：:The Achilles tendon has a high incidence of rupture, and the healing process leads to a disorganized extracellular matrix (ECM) with a high rate of injury recurrence. To evaluate the effects of different conditions of low-level laser (LLL) application on partially tenotomized tendons, adult male rats were divided into...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1236-7
更新日期：2013-09-01 00:00:00
abstract：:This retrospective case-control study aimed to compare 30 versus 40 W power of CO2 laser for the therapy of genitourinary syndrome of menopause (GSM). Postmenopausal women with severe intensity of dyspareunia and dryness were eligible to be included in this study. Primary outcomes were dyspareunia and dryness. Seconda...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2293-8
更新日期：2017-11-01 00:00:00
abstract：:The relative amounts of 5-aminolaevulinic acid (ALA)-induced hydrophobic and hydrophilic porphyrins produced in normal mouse tissue and solid Ehrlich ascites carcinoma in mice were investigated as a function of added glucose, light irradiation and restricted blood flow to the tumour. Protoporphyrin IX (PpIX) is the pr...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/BF02765103
更新日期：1997-10-01 00:00:00
abstract：:To identify the best low level laser photobiomodulation application site at the same irradiation time to increase the viability of the skin flap in rats. Eighteen male rats (Rattus norvegicus: var. Albinus, Rodentia Mammalia) were randomly distributed into three groups (n = 6). Group I (GI) was submitted to simulated ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2694-3
更新日期：2019-07-01 00:00:00
abstract：:Third-degree burn wounds are considered severe injuries because they destroy all the skin layers and may affect subcutaneous tissues, fasciae, muscles, and bones. To favor the healing process of the injured tissues, it is very useful to diminish the occurrence of the inflammatory process. The present study was aimed a...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1213-1
更新日期：2013-07-01 00:00:00
abstract：:The aim of this study was to identify biochemical changes in sciatic nerve (SN) after crush injury and low-level laser therapy (LLLT) with 660 nm and 808 nm by Raman spectroscopy (RS) analysis. A number of 32 Wistar rats were used, divided into four groups (control 1, control 2, LASER 660 nm, and LASER 808 nm). All an...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2627-1
更新日期：2019-04-01 00:00:00
abstract：:The aim of this work was to investigate the long-term effects of a single application of a water-cooled pulsed neodymium yttrium aluminium garnet (Nd:YAG) laser, in combination with scaling and root planing (SRP) for the treatment of periodontal inflammation. Twenty-two patients were included in this split-mouth singl...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-010-0807-8
更新日期：2011-11-01 00:00:00
abstract：:In order to design and manufacture a reliable biomedical sensor, sensitive tests have to be performed. This is of superlative importance as it has to be used for the general public. Keeping this into account, the test mechanism of such an extremely sensitive sensor is being done that involves exhaustive protocols rega...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02945-8
更新日期：2020-09-01 00:00:00
abstract：:The purpose of this study was to evaluate the thickness and qualitative characteristics of the hybrid layer after two cavity preparation methods, using Er:YAG laser in QSP mode and conventional carbide burs. Additionally, two different adhesive techniques were investigated using etch-and-rinse and self-etch adhesive s...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2575-9
更新日期：2019-02-01 00:00:00
abstract：:Low-power laser therapy has become popular in clinical applications including promoting wound healing and pain relief. However, effects of this photoradiation on human hepatoma cells are rarely studied. Previously, we found 808 nm gallium aluminum arsenide (GaAlAs) continuous wave laser had an inhibitory effect on the...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-005-0369-3
更新日期：2006-04-01 00:00:00
abstract：UNLABELLED:Connective tissue graft (CTG), which is considered to be among the best techniques for treating gingival recession, has presented stable long-term results. However, this technique causes morbidity and discomfort in the palatine region due to graft removal at that site. A previous study reports that photobiom...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-016-1988-6
更新日期：2016-09-01 00:00:00
abstract：:Neurofibromatosis type 1 (NF-1) is an autosomal dominant disorder characterized by skin tumours derived from peripheral nerves. It is a clinically diagnosed disorder of a mainly cosmetic concern. There are different excision modalities for treatment of cutaneous neurofibromas; however, none is considered to be univers...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0485-3
更新日期：2008-07-01 00:00:00
abstract：:Laser micromachining with ultrashort pulses has shown great promise for clean, safe surgical treatment of bone tissue. However, comparisons of performance and development of "best practice" have been hampered by the difficulty of comparing results across a wide variety of experimental approaches and under surgically i...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02899-x
更新日期：2020-08-01 00:00:00
abstract：:The post-stimulation response of neural activities plays an important role to evaluate the effectiveness and safety of neural modulation techniques. Previous studies have established the capability of infrared neural modulation (INM) on neural firing regulation in the central nervous system (CNS); however, the dynamic...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02826-0
更新日期：2020-03-01 00:00:00
abstract：:From the very first reports describing the method of action of phototherapy, the effects have been considered to be the result of photochemical and photophysical interactions between the absorbed photons and tissue and not related to secondary changes in tissue or skin temperature. However, thermal effects have been r...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-015-1755-0
更新日期：2015-07-01 00:00:00
abstract：:The aim of the present study was to investigate the influence of low-level red (660 nm) and infrared (780 nm) laser with four different radiance exposures on human umbilical vein endothelial cells (HUVECs) in vitro. HUVECs (1.5 × 104) were incubated in 96-well culture plates. The cells were maintained in M199 medium s...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03016-z
更新日期：2021-02-01 00:00:00
abstract：:Central serous chorioretinopathy (CSC) is a disease characterized by a well-defined serous detachment of the neurosensory retina. Therapeutic options in chronic cases are limited, and side effects can result in a limited response. The aim of this article is to assess the efficacy of subthreshold micropulse laser thera...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03129-5
更新日期：2020-08-19 00:00:00
abstract：:The development of imaging technique to visualize and quantify the structural alteration of the spinal cord injury (SCI) may lead to better understanding and treatments of the injuries. In this work, multiphoton microscopy (MPM) based on two-photon excited fluorescence (TPEF) and second-harmonic generation (SHG) was t...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2630-6
更新日期：2019-04-01 00:00:00
abstract：:Topical anaesthetic cream (TAC) is commonly used as a pre-treatment of ablative fractional resurfacing (AFR) laser. Most of anaesthetic cream contains distilled water as major component. Therefore, pre-operative TAC may interfere the photothermal reaction in the skin treated with fractional carbon-dioxide (FCO2) laser...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-016-2112-7
更新日期：2017-02-01 00:00:00
abstract：:A rabbit model of endophthalmitis was established to evaluate the antiinflammatory effect of low-level laser therapy (LLLT) as an adjunct to treatment for Staphylococcus epidermidis endophthalmitis. Rabbits were randomly divided into three groups to receive intravitreal injections into their left eye: group A received...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0991-1
更新日期：2012-05-01 00:00:00
abstract：:Retinal development involves a complex coordination of events that may be affected by premature delivery, leading to retinopathy of prematurity (ROP), a potential blinding childhood disease. The avascular retina drives further disease progression, with laser ablation reducing unfavorable anatomic outcomes as well as m...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-011-1021-z
更新日期：2013-02-01 00:00:00
abstract：:The aim of this study was to quantitatively evaluate the wettability of dentin after Yb:KYW thin-disk femtosecond-pulsed laser ablation by measuring the contact angle. Different laser parameters were used including different fluences (F), scanning speeds, and scanning line spacings. Crowns of 15 extracted human teeth ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-014-1655-8
更新日期：2015-08-01 00:00:00
abstract：:Different ablation techniques have been utilized in the treatment of Barrett's esophagus (BE) to reduce the risk of degeneration. Treatment complications, risk of recurrence, and buried intestinal metaplasia (IM) are all major concerns. The effect of diode laser treatment on BE, studied in a group of patients over a l...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-010-0836-3
更新日期：2011-03-01 00:00:00
abstract：:Laser therapy has proved effective in the treatment of different tissue injuries but little is known about its effect on the testis. The aim of this review was to synthesize research on the in vivo effect of low-level laser therapy on the seminiferous epithelium. A search was performed in the PubMed/Medline, Scopus, W...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-020-03122-y
更新日期：2020-08-19 00:00:00
abstract：:Photobiomodulation (PBM) has been shown to improve wound healing by promoting mesenchymal stem cell migration and proliferation. However, it remains unknown whether an 808-nm diode laser can influence human gingival mesenchymal stem cells (HGMSCs), and which dose this works well. In the present study, it was found tha...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03040-z
更新日期：2020-10-01 00:00:00
abstract：:The present study was designed to evaluate the effects of low-level laser (Nd:YAG) therapy and occlusal splints in patients with signs and symptoms of temporomandibular disorders (TMD) characterized with myofascial pain (MP). A total of 30 patients were selected after being diagnosed with MP according to the Research ...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-014-1522-7
更新日期：2015-04-01 00:00:00
abstract：:To determine the relation between retinal microstructural changes and the response to 577-nm subthreshold micropulse laser (SML) treatment in chronic central serous chorioretinopathy (cCSC). This retrospective study included 39 eyes of 39 patients with cCSC, treated with the 577-nm SML. The eyes were evaluated in thre...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03225-6
更新日期：2021-01-07 00:00:00
