Abstract：
:Preclinical studies have shown that photodynamic therapy (PDT) enhances immune responses. To examine the role of the direct effects of PDT in liver cancer with regard to enhancement of the antitumor response, we injected PDT-generated H22 liver cancer cell lysate (as a tumor vaccine) intradermally into Kunming mice. In the control group, the cell lysate was substituted with normal saline solution. A liver tumor model was established by the injection of H22 cell suspension. We found that the PDT-generated vaccine significantly increased the percentages of CD4(+), CD8(+), and CD19(+) cells, inhibited tumor growth, and prolonged the survival time. Our findings suggest that PDT-generated vaccines can significantly enhance the antitumor immune response and may have the potential to be used as an adjuvant therapy clinically.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Zhang H,Ma W,Li Ydoi
10.1007/s10103-008-0609-4subject
Has Abstractpub_date
2009-07-01 00:00:00pages
549-52issue
4eissn
0268-8921issn
1435-604Xjournal_volume
24pub_type
杂志文章abstract：:To evaluate the efficacy of laser fibrotomy in patients with oral submucous fibrosis (OSMF) and also to correlate the habit variables causing OSMF. Thirty patients diagnosed clinically and histopathologically with OSMF were included in the study. Laser fibrotomy was done under local anesthesia using Zolar diode laser ...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-018-2531-8
更新日期：2018-11-01 00:00:00
abstract：:Photodynamic therapy (PDT) with photosensitizer is one of the promising modalities for cancer treatment. For clinical use of PDT, screening process should be preceded to enhance sensitivity to PDT. Thus, we investigated a molecular biomarker to determine the sensitivity to pheophorbide a (Pa)-PDT in immortalized human...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1350-1
更新日期：2015-02-01 00:00:00
abstract：:The objective of this study was to assess the effects of 780-nm low-level laser therapy at different periods of 7, 14 and 21 days after cryolesion, including the dose (10 or 50 J/cm(2)), to promote a better muscle repair evidenced by histopathological and immunohistochemical analyses. Fifty-four male rats were divided...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1277-6
更新日期：2014-01-01 00:00:00
abstract：:We evaluated functional and morphological changes after trans-tympanic laser application using several different powers of photobiomodulation (PBM). The left (L) ears of 17 rats were irradiated for 30 min daily over 14 days using a power density of 909.1 (group A, 5040 J), 1136.4 (group B, 6300 J), and 1363.6 (group C...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-015-1851-1
更新日期：2016-02-01 00:00:00
abstract：:To identify the best low level laser photobiomodulation application site at the same irradiation time to increase the viability of the skin flap in rats. Eighteen male rats (Rattus norvegicus: var. Albinus, Rodentia Mammalia) were randomly distributed into three groups (n = 6). Group I (GI) was submitted to simulated ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2694-3
更新日期：2019-07-01 00:00:00
abstract：:In root canal therapy, irrigating solutions are essential to assist in debridement and disinfection. Their spread and action is often restricted by canal anatomy, requiring some form of activation. Lasers have been shown to be promising tools for this purpose (laser-activated irrigation (LAI)). For LAI to be effective...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1307-4
更新日期：2014-09-01 00:00:00
abstract：:Previous studies have been suggested that photodynamic therapy (PDT) can be used as an adjuvant treatment for denture stomatitis. In this study, we evaluated the effects of multiple sessions of PDT on Candida glabrata biofilms in specimens of polymerized acrylic resin formed after 5 days. Subsequently, four applicatio...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2147-4
更新日期：2017-04-01 00:00:00
abstract：:This study was designed to determine the laser dose for the stimulation, zero-bioactivation, and inhibition of normal and neoplastic cells in vitro. The medical use of laser biomodulation has been occurring for decades in the area of tissue healing and inflammatory conditions. The potential to modulate the regeneratio...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-1040-9
更新日期：2012-09-01 00:00:00
abstract：:Induction of matrix synthesis by low-level laser has been demonstrated extensively. However, the question of dose- or power intensity-dependency is under-investigated. To address this issue we chose human osteoblast cell cultures and measured their alkaline phosphatase (ALP) activity after laser irradiation. The cell ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0511-5
更新日期：2008-10-01 00:00:00
abstract：:This study aimed to analyze the effects of light-emitting diode (LED) therapy on sternotomy pain and healing in patients who underwent coronary artery bypass grafting (CABG). The patients were followed for 6 months after the surgery to determine their dehiscence. This study was conducted with 90 volunteers who electiv...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-013-1503-2
更新日期：2014-05-01 00:00:00
abstract：:A disrupted wound repair process often leads to the development of chronic wounds, and pose a major physical, social and economic inconvenience on patients and the public health sector. Chronic wounds are a common complication seen in diabetes mellitus (DM), and often the severity necessitates amputation of the lower ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03041-y
更新日期：2020-06-01 00:00:00
abstract：:The aim of this study was to investigate the effect of different working modes (pulsed and micropulsed) and power settings of a standardized 980-nm diode laser on collateral thermal soft-tissue damage. A total of 108 bovine liver samples were cut with a diode laser at various settings in pulsed and micropulsed mode an...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-1007-x
更新日期：2012-09-01 00:00:00
abstract：:This study aimed to investigate the influence of low-power 830 nm gallium-aluminium-arsenide (GaAlAs) laser [continuous wave (CW) 40 mW and fluence 4 J/cm(2), with total energy density of 16 J/cm(2)] on the healing of human infra-bony defects treated with bioactive glass graft material. Twenty patients with chronic pe...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-008-0576-9
更新日期：2009-05-01 00:00:00
abstract：:This retrospective case-control study aimed to compare 30 versus 40 W power of CO2 laser for the therapy of genitourinary syndrome of menopause (GSM). Postmenopausal women with severe intensity of dyspareunia and dryness were eligible to be included in this study. Primary outcomes were dyspareunia and dryness. Seconda...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2293-8
更新日期：2017-11-01 00:00:00
abstract：:High-intensity focused ultrasound (HIFU) can be applied noninvasively to create focused zones of tissue coagulation on various skin layers. We performed a comparative study of HIFU, evaluating patterns of focused tissue coagulation and ablation upon application thereof. A tissue-mimicking (TM) phantom was prepared wit...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-015-1804-8
更新日期：2015-12-01 00:00:00
abstract：:To determine the relation between retinal microstructural changes and the response to 577-nm subthreshold micropulse laser (SML) treatment in chronic central serous chorioretinopathy (cCSC). This retrospective study included 39 eyes of 39 patients with cCSC, treated with the 577-nm SML. The eyes were evaluated in thre...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03225-6
更新日期：2021-01-07 00:00:00
abstract：:The purpose of this in vitro study was to observe the morphological changes and apical dye penetration at apical dentin surfaces after apicoectomy with conventional techniques and laser beam. Sixty single-rooted extracted teeth were selected for the study. The crowns were resected below the cemento-enamel junction. Th...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0497-z
更新日期：2008-10-01 00:00:00
abstract：:Low-back pain is very frequent, especially in active adult population. There are several different orthopaedic condition that can cause low-back pain, and the pain worsen the quality of life significantly. The treatments vary from drugs, physical therapies, kinesiology, local infiltrations, and so on. Laser therapy ha...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-014-1684-3
更新日期：2015-01-01 00:00:00
abstract：:Treatment of disseminated superficial actinic porokeratosis (DSAP) is poorly standardized. The present review seeks to comprehensively discuss the potential for laser and light modalities in the treatment of DSAP. A systematic review of light and laser treatment modalities was conducted to include 26 cases of patients...
journal_title：Lasers in medical science
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s10103-017-2179-9
更新日期：2017-05-01 00:00:00
abstract：:Despite the positive effects of low-level laser therapy (LLLT) on muscle fatigue before exercises using a single muscle group, the acute effects of LLLT on performance in cardiopulmonary exercise testing (CPET) are poorly understood. We aimed to assess the acute effects of LLLT on physiologic and electromyographic res...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-014-1595-3
更新日期：2014-11-01 00:00:00
abstract：:Acne vulgaris is one of the most common dermatologic disorders encountered in everyday practice. Treatment options for this often psychologically scarring disease are numerous and, for many individuals, provide relief from the disorder. However, factors such as antibiotic resistance and slow onset of action from many ...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-006-0420-z
更新日期：2007-06-01 00:00:00
abstract：:Photobiomodulation (PBM) has been shown to improve wound healing by promoting mesenchymal stem cell migration and proliferation. However, it remains unknown whether an 808-nm diode laser can influence human gingival mesenchymal stem cells (HGMSCs), and which dose this works well. In the present study, it was found tha...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03040-z
更新日期：2020-10-01 00:00:00
abstract：:The present work evaluated the effects of LED light irradiation on the healing of the navels of neonatal dairy calves. Fifty-seven neonatal calves were divided into two groups. Animals had their umbilical stumps immersed in 10% iodine tincture for 60 s, and this process was repeated every 24 h for three consecutive da...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2283-x
更新日期：2017-09-01 00:00:00
abstract：:We report the results of endoscopic laser therapy on 59 patients with upper gastrointestinal vascular ectasia. After 300 sessions, complications were two nonbleeding and three bleeding ulcers, treated successfully with endoscopic therapy. After treatment, blood transfusions were abolished in 61% and reduced in 22% of ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-006-0389-7
更新日期：2006-09-01 00:00:00
abstract：:Retinal development involves a complex coordination of events that may be affected by premature delivery, leading to retinopathy of prematurity (ROP), a potential blinding childhood disease. The avascular retina drives further disease progression, with laser ablation reducing unfavorable anatomic outcomes as well as m...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-011-1021-z
更新日期：2013-02-01 00:00:00
abstract：:Bothropic venom contains a range of biologically active substances capable of causing severe local and systemic envenoming symptomatology within its victims. The snake anti-venom is effective against systemic effects but has no neutralizing effect against the fast developing local effects. Herein, mice gastrocnemius i...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2252-4
更新日期：2017-08-01 00:00:00
abstract：:Hyperthermia treatment can induce component changes on cell. This study explored the potential of Z-scan to improve accuracy in the identification of subtle differences in mouse colon cancer cell line CT26 during hyperthermia treatment. Twenty-one samples were subjected individually to treatment of hyperthermia at 41,...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02759-8
更新日期：2019-10-01 00:00:00
abstract：:The erbium:YSGG and erbium:YAG lasers are used for tissue ablation in dermatology, dentistry and ophthalmology. The purpose of this study was to compare germanium oxide and sapphire optical fibres for transmission of sufficient Q-switched erbium laser pulse energies for potential use in both soft and hard tissue ablat...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-004-0316-8
更新日期：2004-01-01 00:00:00
abstract：:Since time immemorial, tuberculosis (TB) has intimidated the human race owing to its severity. Its socio-economic burden has led to it being a major cause of concern. It is one of the world's major causes of death from a single agent. Since most of the middle- and low-income countries are burdened with TB, sputum smea...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-019-02947-6
更新日期：2020-08-01 00:00:00
abstract：:The aim of the present study was to assess, by means of Raman spectroscopy, the repair of complete surgical tibial fractures fixed with wire osteosynthesis (WO) treated or not with infrared laser (λ780 nm) or infrared light emitting diode (LED) (λ850 ± 10 nm) lights, 142.8 J/cm2 per treatment, associated or not to the...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2508-7
更新日期：2018-11-01 00:00:00
