Abstract:
:Since time immemorial, tuberculosis (TB) has intimidated the human race owing to its severity. Its socio-economic burden has led to it being a major cause of concern. It is one of the world's major causes of death from a single agent. Since most of the middle- and low-income countries are burdened with TB, sputum smear examination using conventional light microscopy is often the only resort for diagnosing TB. However, fluorescence microscopy is used as standard in most high-income countries, owing to its increased sensitivity. Light-emitting diodes (LEDs), being inexpensive, are increasingly gaining popularity as an alternative light source for fluorescence microscopy. It has been found to be highly efficient and has a lot of advantages over the conventional Ziehl-Neelsen-based bright field microscopy. In this review, we discuss about the usefulness of LED-based fluorescence microscopy in diagnosing TB and how it is superior to the other sources of light used.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Ojha A,Banik S,Melanthota SK,Mazumder Ndoi
10.1007/s10103-019-02947-6subject
Has Abstractpub_date
2020-08-01 00:00:00pages
1431-1437issue
6eissn
0268-8921issn
1435-604Xpii
10.1007/s10103-019-02947-6journal_volume
35pub_type
杂志文章,评审abstract::The goal of this study was to assess the ablation, coagulation, and carbonization characteristics of the holmium:YAG (Ho:YAG) laser and thulium fiber lasers (TFL). The Ho:YAG laser (100 W av.power), the quasi-continuous (QCW) TFL (120 W av.power), and the SuperPulsed (SP) TFL (50 W av.power) were compared on a non-fro...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-020-03189-7
更新日期:2020-11-11 00:00:00
abstract::Precise nerve localization is of major importance in both surgery and regional anesthesia. Optically based techniques can identify tissue through differences in optical properties, like absorption and scattering. The aim of this study was to evaluate the potential of optical spectroscopy (diffuse reflectance spectrosc...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2433-1
更新日期:2018-04-01 00:00:00
abstract::Laser excision has been used with increasing success to treat oral leukoplakia. The aim of the present study was to evaluate whether clinical healing of a leukoplakia after laser surgery is associated with a normal functional status of the new epithelium and whether pathological alterations in these parameters are rel...
journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章
doi:10.1007/s10103-011-0941-y
更新日期:2012-01-01 00:00:00
abstract::In this study, shear bond strength (SBS) of metal orthodontic brackets to porcelain following conditioning by Er:YAG (erbium-doped yttrium aluminum garnet) and Nd:YAG (neodymium-doped yttrium aluminum garnet) laser in comparison to conventional methods was evaluated. One hundred glazed porcelain discs with an upper ce...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-010-0878-6
更新日期:2012-03-01 00:00:00
abstract::Photobiomodulation is a treatment that has been widely used in neurotrauma and neurodegenerative diseases. In the present study, low-level laser therapy was administered to patients with spinal cord injury. Twenty-five individuals were divided into two groups: placebo photobiomodulation plus physiotherapy and active p...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-018-2447-3
更新日期:2018-05-01 00:00:00
abstract::In root canal therapy, irrigating solutions are essential to assist in debridement and disinfection. Their spread and action is often restricted by canal anatomy, requiring some form of activation. Lasers have been shown to be promising tools for this purpose (laser-activated irrigation (LAI)). For LAI to be effective...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-013-1307-4
更新日期:2014-09-01 00:00:00
abstract::Excimer laser recanalisation of in-stent restenosis may be a viable modality for improving coronary patency. However, the presence of arterial stents modifies the thermal properties of the irradiated area and may alter temperature patterns generated during ablation. The goal of this study was to evaluate, in vitro, te...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/pl00011348
更新日期:2001-01-01 00:00:00
abstract::Liquid-assisted hard tissue ablation by infrared lasers has extensive clinical application. However, detailed studies are still needed to explore the underlying mechanism. In the present study, the dynamic process of bubble evolution induced by Ho:YAG laser under water without and with bone tissue at different thickne...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-016-1931-x
更新日期:2016-07-01 00:00:00
abstract::The molecular changes in gene expression following ablative laser treatment of skin lesions, such as atrophic scars and UV-damaged skin, are not completely understood. A standardized in vitro model of human skin, to study the effects of laser treatment on human skin, has been recently developed. Therefore, the aim of ...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2175-0
更新日期:2017-05-01 00:00:00
abstract::The aim of this study was to compare the concentration of mast cells (MCs) in the healing process of incisions. Thirty rats were submitted to six linear incisions each, performed in the dorsal skin by carbon dioxide (CO(2)) and diode lasers, electrocautery and conventional scalpel. The animals were euthanized at inter...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-008-0616-5
更新日期:2009-07-01 00:00:00
abstract::Bacterial biofilms are often found in chronically infected wounds. Biofilms protect bacteria from antibiotics and impair wound healing. Surgical debridement is often needed to remove the biofilm from an infected wound. Laser-generated shockwave (LGS) treatment is a novel tissue-sparing treatment for biofilm disruption...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-020-03171-3
更新日期:2020-10-27 00:00:00
abstract::Primary hyperparathyroidism (HPT) in 80% of patients is due to a solitary parathyroid adenoma, while in 20% multigland pathology exists, usually hyperplasia [Scott-Coombes, Surgery, 21(12):309-312, 2003]. Despite recent advances in minimally invasive parathyroidectomy, better preoperative localisation techniques and i...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-006-0397-7
更新日期:2006-12-01 00:00:00
abstract::Diabetes mellitus (DM) is associated with musculoskeletal damage. Investigations have indicated that healing of the surgically tenotomized Achilles tendon was considerably augmented following low-level laser therapy (LLLT) in non-diabetic, healthy animals. The aim of the present study was to evaluate the effect of LLL...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-012-1074-7
更新日期:2013-02-01 00:00:00
abstract::The objective of this study was to determine the efficacy and safety of a novel method of facial rejuvenation using a 2940-nm erbium:YAG laser with Spatially Modulated Ablation™. A pilot study was performed in 16 women with moderate to severe signs of facial aging relative to chronological age, who underwent two treat...
journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章
doi:10.1007/s10103-016-2010-z
更新日期:2016-09-01 00:00:00
abstract::Several studies suggest a biomodulatory influence of low-level laser irradiation in the inflammatory and reparative processes of dental tissues. The aim of this study was to investigate the stimulatory effect of 808-nm laser irradiation on root development of rat molars and also to evaluate the histological reaction o...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-011-0935-9
更新日期:2012-05-01 00:00:00
abstract::Interstitial laser Doppler flowmetry was used to measure the effect of interstitial laser-induced thermotherapy on local blood perfusion in normal rat liver in the peripheral treatment region elevated to hyperthermic temperatures. The Nd:YAG laser emitting at 1064 nm was utilised as heat generation source. The plane-c...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s101030050036
更新日期:1999-06-01 00:00:00
abstract::The aim of the present study was to evaluate the success rate of failed implants re-implanted after surface treatment with CO2 laser. Despite the widespread use of dental implants, there are many incidents of failures. It is believed that lasers can be applied to decontaminate the implant surface without damaging the ...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-016-1921-z
更新日期:2016-07-01 00:00:00
abstract::In periodontal therapy, the use of low-level diode lasers has recently been considered to improve wound healing of the gingival tissue. However, its effects on human gingival epithelial cells (HGECs) remain unknown. The aim of the present study was to examine whether high-frequency low-level diode laser irradiation st...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-013-1292-7
更新日期:2014-07-01 00:00:00
abstract::This study assessed the effect of curcumin as a photosensitizer in antimicrobial photodynamic therapy (aPDT) for the treatment of induced periodontitis in rats. Periodontitis was induced via a ligature around the mandibular first molar on the left side of 96 rats. The ligature was removed 7 days later, and the animals...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2261-3
更新日期:2017-11-01 00:00:00
abstract::We review the different spectroscopic techniques including the most recent laser-induced breakdown spectroscopy (LIBS) for the characterization of materials in any phase (solid, liquid or gas) including biological materials. A brief history of the laser and its application in bioscience is presented. The development o...
journal_title:Lasers in medical science
pub_type: 杂志文章,评审
doi:10.1007/s10103-011-0921-2
更新日期:2011-09-01 00:00:00
abstract::A limited number of studies have evaluated the efficacy and safety of electrode pin fractional radiofrequency (FRF) for periorbital wrinkle treatment in Asian patients, but none have measured noninvasive methodological objective parameters such as periorbital wrinkle area. This study aimed to investigate the efficacy ...
journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章
doi:10.1007/s10103-016-2084-7
更新日期:2017-01-01 00:00:00
abstract::Oral mucositis (OM) and radiodermatitis (RD) are serious side effects of radiotherapy (RT), often leading to its suspension, need for analgesics, and enteral/parenteral nutrition. Laser therapy is becoming a recommended treatment option. This prospective study aimed at demonstrating the beneficial effect of class IV l...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-015-1857-8
更新日期:2016-04-01 00:00:00
abstract::Both high-intensity ultraviolet and narrowband ultraviolet B (NB-UVB) are important therapeutic options for vitiligo management, but high-intensity ultraviolet is more effective than NB-UVB. However, the underlying mechanisms have not been well investigated. Herein, we compare the effects of high-intensity ultraviolet...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-014-1568-6
更新日期:2014-09-01 00:00:00
abstract::In spinal cord injury (SCI), inflammation is a major mediator of damage and loss of function and is regulated primarily by the bone marrow-derived macrophages (BMDMs). Photobiomodulation (PBM) or low-level light stimulation is known to have anti-inflammatory effects and has previously been used in the treatment of SCI...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-019-02941-y
更新日期:2020-09-01 00:00:00
abstract::The development of imaging technique to visualize and quantify the structural alteration of the spinal cord injury (SCI) may lead to better understanding and treatments of the injuries. In this work, multiphoton microscopy (MPM) based on two-photon excited fluorescence (TPEF) and second-harmonic generation (SHG) was t...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-018-2630-6
更新日期:2019-04-01 00:00:00
abstract:PURPOSE:Acne scarring represents a common problem that negatively impacts patients' quality of life. Different types of treatments are currently available for this dermatological condition. This study evaluates the efficacy of a new 675-nm laser source system on acne scars with the use of established parameters that gu...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-020-03063-6
更新日期:2021-02-01 00:00:00
abstract::To evaluate the efficacy of short-term subthreshold micropulse yellow laser photocoagulation (SMYLP) on eyes with diabetic macular edema (DME) with different central foveal thicknesses (CFT). Eighty eyes of 40 patients who had previously undergone ranibizumab treatment for DME and who subsequently had recurrent macula...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-018-2672-9
更新日期:2019-07-01 00:00:00
abstract::From the very first reports describing the method of action of phototherapy, the effects have been considered to be the result of photochemical and photophysical interactions between the absorbed photons and tissue and not related to secondary changes in tissue or skin temperature. However, thermal effects have been r...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-015-1755-0
更新日期:2015-07-01 00:00:00
abstract::Patients with pain avoid movements, leading to a gradual impairment of their physical condition and functionality. In this context, the use of ultrasound (US) and low-level laser therapy (LLLT) show promising results for nonpharmacological and noninvasive treatment. The aim of this study was evaluated the synergistic ...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-014-1659-4
更新日期:2015-01-01 00:00:00
abstract::Bactericidal and detoxification effects of diode laser (DL) have been reported in periodontal treatment. The objective of this study was investigating the additional effect of DL with nonsurgical periodontal treatment on the red complex bacteria in type 2 diabetes mellitus (DM) patients with chronic periodontitis (CP)...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-020-02997-1
更新日期:2020-08-01 00:00:00