Abstract：
:Primary hyperparathyroidism (HPT) in 80% of patients is due to a solitary parathyroid adenoma, while in 20% multigland pathology exists, usually hyperplasia [Scott-Coombes, Surgery, 21(12):309-312, 2003]. Despite recent advances in minimally invasive parathyroidectomy, better preoperative localisation techniques and intraoperative parathyroid hormone (PTH) monitoring, a 4% failure rate [Grant CS, Thompson G, Farley D, Arch Surg, 140:47-479, 2005] persists making accurate differentiation between adenomas and hyperplasia of prime importance. We investigated the ability of Raman spectroscopy to accurately differentiate between parathyroid adenomas and hyperplasia. Raman spectra were measured at defined points on the parathyroid tissue sections using a bench-top microscopy system. Multivariate analysis of the spectra was carried out to construct a diagnostic algorithm correlating spectral results with the histopathological diagnosis. A total of 698 spectra were analysed. Principal-component (PCA)-fed linear discriminant analysis (LDA) used to construct a diagnostic algorithm. Detection sensitivity for parathyroid adenomas was 95% and hyperplasia was 93%. These preliminary results indicate that Raman spectroscopy is potentially an excellent tool to differentiate between parathyroid adenomas and hyperplasia.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Das K,Stone N,Kendall C,Fowler C,Christie-Brown Jdoi
10.1007/s10103-006-0397-7subject
Has Abstractpub_date
2006-12-01 00:00:00pages
192-7issue
4eissn
0268-8921issn
1435-604Xjournal_volume
21pub_type
杂志文章abstract：:Low-energy laser irradiation (Ga-Al-As semiconductor laser, output 50 mW) was applied to rat osteoclast precursor cells for 1, 3, 6, or 10 min at 24-h intervals during the culture period. The number of tartrate-resistant acid phosphatase positive multinucleate cells was increased by approximately 1.3-fold in the 3- an...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-005-0368-4
更新日期：2006-04-01 00:00:00
abstract：:Recently, investigations suggest the benefits of low-level laser (light) therapy (LLLT) in noninvasive treatment of cellulite, improvement of body countering, and control of lipid profile. However, the underlying key mechanism for such potential effects associated to aerobic plus resistance training to reduce body fat...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-015-1759-9
更新日期：2015-07-01 00:00:00
abstract：:The aim of this in vitro study was to assess the effect of Er:YAG laser surface treatment on the tensile bond strength of a sealant in permanent teeth. A total of 30 sound third molars were selected and embedded in cold-cure acrylic resin. The enamel surfaces were flattened by a grinding. The teeth were randomly divid...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-010-0869-7
更新日期：2012-03-01 00:00:00
abstract：:Bisphosphonate-related osteonecrosis of the jaw is a well-known potential side effect of long-term bisphosphonate therapy; the primary objective of the treatment should be to improve patient quality of life through pain and infection management, to prevent the development of new lesions, and to slow disease progressio...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-016-1929-4
更新日期：2016-08-01 00:00:00
abstract：:This study aims to evaluate whether optical coherence tomography (OCT) using both the surface and the endoluminal technique is feasible to investigate the locations and degree of encrustation process in clinically used ureteral stents. After removal from patients, 14 polyurethane JJ stents were investigated. A fresh J...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1177-1
更新日期：2013-05-01 00:00:00
abstract：:This study analyzed the effects of photobiomodulation (PBM) with low-level laser therapy on nociceptive behavior and neuronal activity in the trigeminal nucleus after experimental unilateral temporomandibular joint (TMJ) disc injury. The animals were divided into 4 groups (n = 10 each): group 1, surgical injury of the...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02842-0
更新日期：2020-03-01 00:00:00
abstract：:Photodynamic rejuvenation therapy (PDRT) is a growing field in cosmetic dermatology. In this study, different sources of light (a yellow laser, a red laser and ultraviolet A (UVA) lamps) were used to activate a second-generation photosensitiser, hypericin. Uptake of hypericin was monitored over 24 h and efficacy of PD...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1115-2
更新日期：2013-02-01 00:00:00
abstract：:The optical properties of the skin (absorption coefficient, scattering coefficient, refractive index) may serve to characterize the skin and are important for correct light dosimetry in many optical diagnostic procedures and laser treatments especially photodynamic therapy and laser therapy. We determined in vivo the ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-009-0725-9
更新日期：2010-03-01 00:00:00
abstract：:This study aimed to evaluate the surface changes caused in zirconia by different surface treatments and the influence of the surface treatment and cement selection on bonding to zirconia under aging. Sintered zirconia specimens were divided into five groups (n = 31) based on the surface treatment, namely, control, air...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1221-1
更新日期：2014-01-01 00:00:00
abstract：:Photobiomodulation is a treatment that has been widely used in neurotrauma and neurodegenerative diseases. In the present study, low-level laser therapy was administered to patients with spinal cord injury. Twenty-five individuals were divided into two groups: placebo photobiomodulation plus physiotherapy and active p...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-018-2447-3
更新日期：2018-05-01 00:00:00
abstract：:A retrospective study was conducted to investigate the incidence of reported adverse responses after epilatory laser treatment to control the growth of facial hair in patients with polycystic ovary syndrome. Forty-eight patients received a median of 6 (range 2-11) treatments with an Aesculap ruby laser during a 704 da...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0451-0
更新日期：2008-01-01 00:00:00
abstract：:The present study aimed to evaluate in vitro whether the low-level laser (LLL) delivering fractionated total energy (multiple irradiation) or single irradiation stimulates regeneration-associated events (viability and proliferation) in stem cells from human exfoliated deciduous teeth (SHED). Cells received LLL irradia...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02836-y
更新日期：2019-12-01 00:00:00
abstract：:We evaluated functional and morphological changes after trans-tympanic laser application using several different powers of photobiomodulation (PBM). The left (L) ears of 17 rats were irradiated for 30 min daily over 14 days using a power density of 909.1 (group A, 5040 J), 1136.4 (group B, 6300 J), and 1363.6 (group C...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-015-1851-1
更新日期：2016-02-01 00:00:00
abstract：:The aim of the study was to investigate the effect of low-level 809 nm laser irradiation on the proliferation rate of human larynx carcinoma cells in vitro. Epithelial tumor cells were obtained from a laryngeal carcinoma and cultured under standard conditions. For laser treatment the cells were spread on 96-well tissu...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-003-0265-7
更新日期：2003-01-01 00:00:00
abstract：:The published online version contains mistake. Warren S. Warren was not included in the author group section. Corrected author group section is shown above. ...
journal_title：Lasers in medical science
pub_type： 杂志文章,已发布勘误
doi：10.1007/s10103-017-2339-y
更新日期：2017-12-01 00:00:00
abstract：:The most common cause of laryngitis is the laryngopharyngeal reflux disease. The symptoms of laryngitis can be hoarseness, globus, chronic cough, voice fatigue, throat pain, and dysphagia. Low-level laser therapy (LLLT) is beneficial to reduce the pain and inflammatory response without side effects. Therefore, LLLT ma...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1323-4
更新日期：2014-01-01 00:00:00
abstract：:We evaluated the acute electrophysiological effects of low-energy pulsed laser irradiation on isolated frog sciatic nerve measured by extracellular recording technique. A pulsed gallium-arsenide (GaAs) laser (wavelength: 904 nm, pulse duration 220 ns, peak power per pulse: 27W, spot size: 0.28 cm(2), total applied ene...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-002-8268-3
更新日期：2002-01-01 00:00:00
abstract：:Reepithelialization and wound closure are the desired outcome for several ulcerative conditions. Such resolution reduces the possibility of wound contamination and maintenance of the injury and improves the reestablishment of tissue morphology and functions. Investigators are seeking adjuvant therapies that can accele...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2176-z
更新日期：2018-02-01 00:00:00
abstract：:In this study, we compared the microleakage of composite fillings cured with halogen bulb, LED and argon ion laser (488 nm). Twenty-four extracted human molars were divided randomly in three groups. Six cavities were prepared on the coronal part of each tooth. Standard cavities (1.7 x 2 mm) were prepared. Cavities wer...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0504-4
更新日期：2009-01-01 00:00:00
abstract：:Inflammation of synovial membrane and degeneration of articular cartilage in osteoarthritis (OA) lead to major changes in joint space width (JSW) and biochemical components such as collagen-II telopeptide (CTX-II) and matrix metallo protineases (MMP-3, 8, and 13). Low-level laser therapy (LLLT) is thought to have an a...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-016-2114-5
更新日期：2017-02-01 00:00:00
abstract：:Microvascular surgery is time consuming and requires high expertise. Laser-assisted vascular anastomosis (LAVA) is a promising sutureless technique that has the potential to facilitate this procedure. In this study, we evaluate the handling of our soldering material and the 1-week patency rate in a porcine model. Six ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2250-6
更新日期：2017-08-01 00:00:00
abstract：:Biostimulatory effect of cell proliferation and bone formation by laser irradiation has been reported, however, very little is known about the molecular basis of mechanisms. We previously constructed the cDNA library of mouse osteoblastic cells (MC3T3-E1) which enhanced gene expression by laser irradiation using a sub...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/pl00011357
更新日期：2001-01-01 00:00:00
abstract：:Benzene is volatile organic hydrocarbon which is widely used in a wide range of industries. Studies have shown that exposure to benzene consequences serious health risks for human. Understanding the effect and risks of environmental hazard materials in the laser therapy of skin is interesting which can show useful or ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03211-y
更新日期：2021-01-07 00:00:00
abstract：:This study aimed to evaluate in vitro performance of near-infrared laser transillumination (NIR-LTI) for detecting early occlusal caries in permanent teeth and compare it with quantitative light-induced fluorescence (QLF), DIAGNOdent Pen (DDPen), and conventional radiography (CR). Ninety-four occlusal surfaces present...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-014-1704-3
更新日期：2015-09-01 00:00:00
abstract：:We report results on the use of organically modified silica nanoparticles (SiNp) as a vehicle for the delivery of curcumin in human oral cancer cells for improvement of uptake and phototoxicity. Nanoformulated drug (curcumin-SiNp complex) was prepared by postloading curcumin in SiNp, and the complex was soluble in aqu...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1357-7
更新日期：2014-03-01 00:00:00
abstract：:Primary hepatocellular carcinoma (HCC) and colon carcinoma are two of the most common clinical malignancies along with high morbidity and mortality. As low-power laser irradiation (LPLI) can induce cytotoxicity or cell apoptosis on several types of hyperplasia, LPLI may be a potential alternative treatment for gastroe...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02869-3
更新日期：2020-04-01 00:00:00
abstract：:The traditional needle cricothyroidotomy procedure is performed blindly without any medical equipment. Complications including posterior tracheal wall perforation, accidental vessel puncture, and missed tracheal puncture are reported. Therefore, we proposed a dual-wavelength fiber-optic technique based on the techniqu...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03065-4
更新日期：2020-07-23 00:00:00
abstract：:Bone morphogenetic proteins (BMPs) are secreted signaling molecules belonging to the transforming growth factor-beta (TGF-beta) superfamily. The objective of this study was to determine how gallium-aluminum-arsenium (GaAlAs) 650 nm laser influenced the action of BMPs on bone defects created in rat femurs. The sample c...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0595-6
更新日期：2009-09-01 00:00:00
abstract：:The aim of this in vitro study was to evaluate the effect of laser treatment on shear bond strength of a self-adhesive flowable resin composite to human dentin. Eighty extracted sound human molar teeth were used for the study. The teeth were sectioned mesiodistally and embedded in acrylic blocks. The dentin surfaces w...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1158-4
更新日期：2013-01-01 00:00:00
abstract：:This study assessed the effect of curcumin as a photosensitizer in antimicrobial photodynamic therapy (aPDT) for the treatment of induced periodontitis in rats. Periodontitis was induced via a ligature around the mandibular first molar on the left side of 96 rats. The ligature was removed 7 days later, and the animals...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2261-3
更新日期：2017-11-01 00:00:00
