Abstract：
:The most common cause of laryngitis is the laryngopharyngeal reflux disease. The symptoms of laryngitis can be hoarseness, globus, chronic cough, voice fatigue, throat pain, and dysphagia. Low-level laser therapy (LLLT) is beneficial to reduce the pain and inflammatory response without side effects. Therefore, LLLT may be a useful tool for the treatment of laryngitis. This study proposes to analyze the effect of laser therapy in a model of reflux-induced laryngitis. The animals were randomly put into three groups: control--non-intubated; nasogastric intubation--intubated; and nasogastric intubation with laser therapy-intubated treated with 105-J/cm(2) laser irradiation. For the induction of laryngitis, the animals were anesthetized and a nasogastric tube was inserted through the nasopharynx until it reached the stomach, for 1 week. Thereafter, measurement of myeloperoxidase activity and the histopathological procedures were performed. In conclusion, we observed in this study that 105-J/cm(2) infrared laser reduced the influx of neutrophils in rats, and it improved the reparative collagenization of the laryngeal tissues.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Marinho RR,Matos RM,Santos JS,Ribeiro MA,Ribeiro RA,Lima RC Jr,Albuquerque RL Jr,Thomazzi SMdoi
10.1007/s10103-013-1323-4subject
Has Abstractpub_date
2014-01-01 00:00:00pages
239-43issue
1eissn
0268-8921issn
1435-604Xjournal_volume
29pub_type
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