Abstract：
:Photodynamic therapy (PDT) is used for the prevention and treatment of non-melanoma skin cancer. Until recently, clinically approved indications have been restricted to actinic keratoses, nodular and superficial basal cell carcinoma, and, since 2006, Bowen disease. However, the range of indications has been expanding continuously. PDT is also used for the treatment of non-malignant conditions such as acne vulgaris and leishmaniasis, as well as for treating premature skin aging due to sun exposure. The production of reactive oxygen intermediates like singlet oxygen depends on the light dose applied as well as the concentration and localization of the photosensitizer in the diseased tissue. Either cytotoxic effects resulting in tumor destruction or immunomodulatory effects improving inflammatory skin conditions are induced. Treating superficial non-melanoma skin cancer, PDT has been shown to be highly efficient, despite the low level of invasiveness. The excellent cosmetic results after treatment are beneficial, too.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Choudhary S,Nouri K,Elsaie MLdoi
10.1007/s10103-009-0716-xsubject
Has Abstractpub_date
2009-11-01 00:00:00pages
971-80issue
6eissn
0268-8921issn
1435-604Xjournal_volume
24pub_type
杂志文章,评审abstract：:Tissue characterisation by fluorescence imaging, using exogenous fluorophores, is a promising method for cancer detection. Histochemical alterations in the composition of mucins, when neoplastic transformations occur, could be exploited to derive more selective fluoroprobes indicative of early malignant transformation...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/pl00011361
更新日期：2001-01-01 00:00:00
abstract：:This retrospective case-control study aimed to compare 30 versus 40 W power of CO2 laser for the therapy of genitourinary syndrome of menopause (GSM). Postmenopausal women with severe intensity of dyspareunia and dryness were eligible to be included in this study. Primary outcomes were dyspareunia and dryness. Seconda...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2293-8
更新日期：2017-11-01 00:00:00
abstract：:The traditional needle cricothyroidotomy procedure is performed blindly without any medical equipment. Complications including posterior tracheal wall perforation, accidental vessel puncture, and missed tracheal puncture are reported. Therefore, we proposed a dual-wavelength fiber-optic technique based on the techniqu...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03065-4
更新日期：2020-07-23 00:00:00
abstract：:Wound healing is a very complex process, some phases of which have only recently been explained. Magnetic and electromagnetic fields can modulate this process in a non-thermal way. The aim of this research was to compare the influence of constant and pulsed electromagnetic fields and low-level laser therapy (LLLT) on ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0564-0
更新日期：2009-05-01 00:00:00
abstract：:Various therapies for the treatment of sprains have emerged as advances occur in biomedical engineering and photobiology. Therapy with coherent and non-coherent light is a treatment modality for various musculoskeletal injuries. The main certified phototherapy benefits are the reduction of nociceptive processes and th...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-018-2460-6
更新日期：2018-07-01 00:00:00
abstract：:Knee osteoarthritis (KOA) is a common degenerative disease in which several treatments and treatment associations have been investigated. This review analyzed the efficacy of the association of photobiomodulation therapy (PBMT) and exercises for people with KOA in randomized controlled clinical trials. PubMed, Scopus,...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-020-03223-8
更新日期：2021-01-03 00:00:00
abstract：:Compensatory hypertrophy (CH) occurs due to excessive mechanical load on a muscle, promoting an increase in the size of muscle fibers. In clinical practice, situations such as partial nerve injuries, denervation, and muscle imbalance caused by trauma to muscles and nerves or diseases that promote the loss of nerve con...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03095-y
更新日期：2020-07-07 00:00:00
abstract：:Antimicrobial photodynamic therapy represents an alternative method of killing resistant pathogens. Efforts have been made to develop delivery systems for hydrophobic drugs to improve the photokilling. This study evaluated the photodynamic effect of chloro-aluminum phthalocyanine (ClAlPc) encapsulated in nanoemulsions...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1354-x
更新日期：2015-02-01 00:00:00
abstract：:The optical properties of the skin (absorption coefficient, scattering coefficient, refractive index) may serve to characterize the skin and are important for correct light dosimetry in many optical diagnostic procedures and laser treatments especially photodynamic therapy and laser therapy. We determined in vivo the ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-009-0725-9
更新日期：2010-03-01 00:00:00
abstract：:Skin flaps are still a matter of concern among surgeons, as failures can occur leading to flap necrosis. However, low-level laser irradiation has been reported as an effective tool to improve the viability of ischemic flaps, yet its mechanisms of action remain unclear. We investigated the effect of low-level laser irr...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-1011-1
更新日期：2012-05-01 00:00:00
abstract：:Induction of matrix synthesis by low-level laser has been demonstrated extensively. However, the question of dose- or power intensity-dependency is under-investigated. To address this issue we chose human osteoblast cell cultures and measured their alkaline phosphatase (ALP) activity after laser irradiation. The cell ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0511-5
更新日期：2008-10-01 00:00:00
abstract：:The aim of this study was to evaluate the bactericidal effect of ultraviolet (UV) light at 265-nm (UVC) and 310-nm (UVB) wavelengths from a newly developed UV light-emitting diode (LED) device against cariogenic bacteria in vitro. Suspensions of Streptococcus mutans (S. mutans) and Streptococcus sobrinus were directly...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2685-4
更新日期：2019-07-01 00:00:00
abstract：:A limited number of studies have evaluated the efficacy and safety of electrode pin fractional radiofrequency (FRF) for periorbital wrinkle treatment in Asian patients, but none have measured noninvasive methodological objective parameters such as periorbital wrinkle area. This study aimed to investigate the efficacy ...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-016-2084-7
更新日期：2017-01-01 00:00:00
abstract：:Although some studies claim to the increase of composite resin adhesion to Er:YAG-laser-treated dentin, there are still no reports on the adhesion of composite resin cements to the irradiated surface. This in vitro study evaluated the tensile bond strength (TBS) of a composite resin cement to dentin treated with the E...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-006-0433-7
更新日期：2007-09-01 00:00:00
abstract：:Laser micromachining with ultrashort pulses has shown great promise for clean, safe surgical treatment of bone tissue. However, comparisons of performance and development of "best practice" have been hampered by the difficulty of comparing results across a wide variety of experimental approaches and under surgically i...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02899-x
更新日期：2020-08-01 00:00:00
abstract：:Bothropic venom contains a range of biologically active substances capable of causing severe local and systemic envenoming symptomatology within its victims. The snake anti-venom is effective against systemic effects but has no neutralizing effect against the fast developing local effects. Herein, mice gastrocnemius i...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2252-4
更新日期：2017-08-01 00:00:00
abstract：:The present work evaluated the effects of LED light irradiation on the healing of the navels of neonatal dairy calves. Fifty-seven neonatal calves were divided into two groups. Animals had their umbilical stumps immersed in 10% iodine tincture for 60 s, and this process was repeated every 24 h for three consecutive da...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2283-x
更新日期：2017-09-01 00:00:00
abstract：:The objective of this study was to describe the dynamics of water heating carried out by continuous laser radiation with wavelengths 1.47, 1.55, and 1.94 μm with different types of fibers used for endovenous laser coagulation. The study was conducted in water using high-speed surveying of the heating process through t...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03184-y
更新日期：2020-11-07 00:00:00
abstract：:This study aimed to assess the effect of toluidine blue (TB)-mediated photodynamic inactivation of periodontal pathogens (PP) from periodontopathic patients. Photodynamic therapy (PDT) was carried out using TB and 635 nm laser light irradiation. The bactericidal effect was evaluated, and important PDT parameters inclu...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0454-x
更新日期：2008-01-01 00:00:00
abstract：:The aim of this study was to compare the rate of tooth displacement, quantity of root resorption, and alveolar bone changes in five groups: corticopuncture (CP), low-level laser therapy (LLLT), CP combined with LLLT (CP + LLLT), control (C), and negative control (NC). A total of 60 half-maxilla from 30 male Wistar rat...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2421-5
更新日期：2018-05-01 00:00:00
abstract：:Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is a side effect of bisphosphonate therapy. However, its pathophysiology is not yet fully elucidated, and effective treatment of BRONJ remains unclear. The aim of this study is to investigate the effects of alendronate on oral keratinocytes and of low-level laser...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1382-6
更新日期：2015-02-01 00:00:00
abstract：:Lasers have many favorable features as a light source owing to their monochromaticity and coherence. This study examined the mechanical properties of composite resins that were light-cured using a diode-pumped solid state (DPSS) laser. Eight composite resins were light-cured using four different light sources (one qua...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1117-0
更新日期：2013-02-01 00:00:00
abstract：:The biodistribution and pharmacokinetics of meta-tetra(hydroxyphenyl)chlorin (mTHPC)(1) have been documented in humans, rats, dogs and rabbits. It has been demonstrated to be an effective photodynamic therapy agent for treatment of squamous cell carcinoma. Squamous cell carcinoma is a common feline neoplasm, causing s...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s101030200014
更新日期：2002-01-01 00:00:00
abstract：:The objective of this study was to determine the efficacy and safety of a novel method of facial rejuvenation using a 2940-nm erbium:YAG laser with Spatially Modulated Ablation™. A pilot study was performed in 16 women with moderate to severe signs of facial aging relative to chronological age, who underwent two treat...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-016-2010-z
更新日期：2016-09-01 00:00:00
abstract：:We report results on the use of organically modified silica nanoparticles (SiNp) as a vehicle for the delivery of curcumin in human oral cancer cells for improvement of uptake and phototoxicity. Nanoformulated drug (curcumin-SiNp complex) was prepared by postloading curcumin in SiNp, and the complex was soluble in aqu...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1357-7
更新日期：2014-03-01 00:00:00
abstract：:The published online version contains mistake. Warren S. Warren was not included in the author group section. Corrected author group section is shown above. ...
journal_title：Lasers in medical science
pub_type： 杂志文章,已发布勘误
doi：10.1007/s10103-017-2339-y
更新日期：2017-12-01 00:00:00
abstract：:The aim of this in vitro study was to assess the effect of Er:YAG laser surface treatment on the tensile bond strength of a sealant in permanent teeth. A total of 30 sound third molars were selected and embedded in cold-cure acrylic resin. The enamel surfaces were flattened by a grinding. The teeth were randomly divid...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-010-0869-7
更新日期：2012-03-01 00:00:00
abstract：:A consistently effective treatment for small leg veins (< or = 1.0 mm) is still being sought. The efficacy of an 810 nm diode laser in vein removal was assessed in a preliminary study. Fifteen females, skin types I to III, vein diameters 0.5-1 mm, aged from 25 to 42 years, participated in the study. An 810 nm diode la...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-004-0295-9
更新日期：2004-01-01 00:00:00
abstract：:The aim of the present study was to evaluate the success rate of failed implants re-implanted after surface treatment with CO2 laser. Despite the widespread use of dental implants, there are many incidents of failures. It is believed that lasers can be applied to decontaminate the implant surface without damaging the ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-1921-z
更新日期：2016-07-01 00:00:00
abstract：:The purpose of this study was to compare the effectiveness of 1470- and 980-nm lasers with regard to power output, complications, recanalization rates, and treatment response. We prospectively evaluated the effectiveness of endovenous laser ablation (EVLA) in a total of 152 great and small saphenous veins from 96 pati...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-015-1768-8
更新日期：2015-07-01 00:00:00
