Abstract：
:Induction of matrix synthesis by low-level laser has been demonstrated extensively. However, the question of dose- or power intensity-dependency is under-investigated. To address this issue we chose human osteoblast cell cultures and measured their alkaline phosphatase (ALP) activity after laser irradiation. The cell cultures were irradiated periodically by 690 nm radiation via optical transmission fiber-based laser needles, reaching into the culture dishes. The osteoblasts showed no induction of ALP activity when we used a single laser needle stimulation with a laser irradiance of 51 mW/cm(2), an increase of approximately 43% at 102 mW/cm(2) irradiance (two needles per well) and a ninefold increase at 204 mW/cm(2) irradiance (four needles per well), leaving the temperature of the culture medium unaffected. We concluded that the osteoblastic response in ALP activity to a laser stimulus shows a logarithmic relationship, with a distinct threshold, rather than a linear dose-dependency. Secondly, the laser irradiance, rather than the dose, is relevant for the impact of the laser.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Haxsen V,Schikora D,Sommer U,Remppis A,Greten J,Kasperk Cdoi
10.1007/s10103-007-0511-5subject
Has Abstractpub_date
2008-10-01 00:00:00pages
381-4issue
4eissn
0268-8921issn
1435-604Xjournal_volume
23pub_type
杂志文章abstract：:Hyperthermia treatment can induce component changes on cell. This study explored the potential of Z-scan to improve accuracy in the identification of subtle differences in mouse colon cancer cell line CT26 during hyperthermia treatment. Twenty-one samples were subjected individually to treatment of hyperthermia at 41,...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02759-8
更新日期：2019-10-01 00:00:00
abstract：:This study aimed to evaluate in vitro performance of near-infrared laser transillumination (NIR-LTI) for detecting early occlusal caries in permanent teeth and compare it with quantitative light-induced fluorescence (QLF), DIAGNOdent Pen (DDPen), and conventional radiography (CR). Ninety-four occlusal surfaces present...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-014-1704-3
更新日期：2015-09-01 00:00:00
abstract：:We aimed at examining the effects of a percentage of air/water in spray on the cutting efficiency of Er,Cr:YSGG laser for enamel and dentin. The intensity and frequency of irradiation were 3.0 W and 20 Hz for the enamel surface and 2.0 W and 20 Hz for the dentin surface, respectively. Flattened surfaces of enamel and ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2607-5
更新日期：2019-02-01 00:00:00
abstract：:The purpose of this study was to evaluate the surface and intrapulpal temperatures after treatments with different bleaching gels subjected to different types of light activation. A K-type thermocouple and infrared thermometer were used to measure the temperature increase during the 15- or 30-min treatment period. Lig...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1366-6
更新日期：2015-02-01 00:00:00
abstract：:Endometriosis is a chronic disease affecting mainly women of the reproductive age. Its most common manifestations include impaired fecundity, pelvic pain, and dyschezia. Laparoscopic removal of endometriotic foci remains to be the gold standard for the treatment of endometriosis. More effective techniques of endoscopi...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-014-1630-4
更新日期：2015-01-01 00:00:00
abstract：:Detection of demineralization of root surface caries is an important issue since preventive approaches prolong tooth life. Quantitative light-induced fluorescence (QLF) has been shown to be useful for the laboratory assessment of demineralization of root surfaces. The aim of this study was to determine the demineraliz...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0899-9
更新日期：2012-03-01 00:00:00
abstract：:The Nd:YAG laser efficacy associated with conventional treatment for bacterial reduction has been investigated throughout literature. The purpose of this study was to evaluate the bacterial reduction after Nd:YAG laser irradiation associated with scaling and root planning in class II furcation defects in patients with...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s10103-007-0482-6
更新日期：2008-10-01 00:00:00
abstract：:Skin represents an interface between internal and external environment; it protects human body by regulating the water loss and the maintenance of body temperature, defending against irritant and pathogen agents, and against physical, chemical, and UV damage. It provides to essential physiological functions, such as t...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2635-1
更新日期：2019-04-01 00:00:00
abstract：:Quantitative characterization of skin collagen on photo-thermal response and its regeneration process is an important but difficult task. In this study, morphology and spectrum characteristics of collagen during photo-thermal response and its light-induced remodeling process were obtained by second-harmonic generation...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1296-3
更新日期：2014-01-01 00:00:00
abstract：:The aim of this study was to evaluate the degree of conversion (DC) and to identify the viscoelastic properties: storage modulus (E'), loss modulus (E"), tangent delta (tan δ), and glass transition temperature (T g ) of a microhybrid resin-composite light-activated by three different protocols. A Filtek Z250 (3 M ESPE...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-014-1572-x
更新日期：2015-05-01 00:00:00
abstract：:Infrared laser therapy is used for skeletal muscle repair based on its biostimulative effect on satellite cells. However, shortening of telomere length limits regenerative potential in satellite cells, which occurs after each cell division cycle. Also, laser therapy could be more effective on non-physiologic tissues. ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-1956-1
更新日期：2016-08-01 00:00:00
abstract：:Low-energy laser irradiation (Ga-Al-As semiconductor laser, output 50 mW) was applied to rat osteoclast precursor cells for 1, 3, 6, or 10 min at 24-h intervals during the culture period. The number of tartrate-resistant acid phosphatase positive multinucleate cells was increased by approximately 1.3-fold in the 3- an...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-005-0368-4
更新日期：2006-04-01 00:00:00
abstract：:Recent studies have demonstrated the beneficial effect of low-power lasers and polarized light on wound healing, inflammation, and the treatment of rheumatologic and neurologic disorders. The overall effect of laser irradiation treatment is still controversial due to the lack of studies on the biochemical mechanisms a...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2398-0
更新日期：2018-04-01 00:00:00
abstract：:Bactericidal and detoxification effects of diode laser (DL) have been reported in periodontal treatment. The objective of this study was investigating the additional effect of DL with nonsurgical periodontal treatment on the red complex bacteria in type 2 diabetes mellitus (DM) patients with chronic periodontitis (CP)...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-020-02997-1
更新日期：2020-08-01 00:00:00
abstract：:Low-level laser therapy (LLLT), widely used in physiotherapy, has been known to enhance wound healing and stimulate cell proliferation, including fibroblast and endothelial cells. Applying LLLT can increase cell proliferation in many kinds of cells including fibroblasts and endothelial cells. However, the protective m...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2364-x
更新日期：2018-02-01 00:00:00
abstract：:Bothropic venom contains a range of biologically active substances capable of causing severe local and systemic envenoming symptomatology within its victims. The snake anti-venom is effective against systemic effects but has no neutralizing effect against the fast developing local effects. Herein, mice gastrocnemius i...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2252-4
更新日期：2017-08-01 00:00:00
abstract：:Compensatory hypertrophy (CH) occurs due to excessive mechanical load on a muscle, promoting an increase in the size of muscle fibers. In clinical practice, situations such as partial nerve injuries, denervation, and muscle imbalance caused by trauma to muscles and nerves or diseases that promote the loss of nerve con...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03095-y
更新日期：2020-07-07 00:00:00
abstract：:The purpose of this study is to evaluate microtensile bond strength (μTBS) of an etch-and-rinse adhesive to enamel and dentin after treatment with Er:YAG laser using different pulse durations. Extracted human molars were flattened to obtain enamel or dentin surfaces. The enamel specimens (E) were divided into nine gro...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-010-0830-9
更新日期：2012-01-01 00:00:00
abstract：:Photobiomodulation (PBM) has been shown to improve wound healing by promoting mesenchymal stem cell migration and proliferation. However, it remains unknown whether an 808-nm diode laser can influence human gingival mesenchymal stem cells (HGMSCs), and which dose this works well. In the present study, it was found tha...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03040-z
更新日期：2020-10-01 00:00:00
abstract：:Since the introduction of laser in clinical practice, different wavelengths have been used for oral surgery on the basis of the different characteristics and affinities of each one. The aim of this study was a comparison of different laser wavelengths in relation to both thermal increase and "histological quality" in ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1081-8
更新日期：2013-02-01 00:00:00
abstract：:Methicillin-resistant Staphylococcus aureus (MRSA) is an important cause of infections in humans. Photodynamic therapy using blue light (450 nm) could possibly be used to reduce MRSA on different human tissue surfaces without killing the human cells. It could be less harmful than 300-400 nm light or common disinfectan...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02774-9
更新日期：2019-12-01 00:00:00
abstract：:The purpose of this study was to evaluate the acid resistance of erbium:yttrium-aluminum-garnet (Er:YAG) lased sub-surface dentin using a scanning electron microscope (SEM). Dentin disks were exposed to a single pulse of Er:YAG laser irradiation at 80 mJ/pulse under water spray, with the contact sapphire tip vertical ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0553-3
更新日期：2009-07-01 00:00:00
abstract：:The objective of this study was to evaluate the microbiological and clinical outcomes following nonsurgical treatment by either scaling and root planing, combination of Nd:YAG and Er:YAG lasers, or by Er:YAG laser treatment alone. The study involved 60 patients with generalized chronic periodontitis, randomly assigned...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-018-2491-z
更新日期：2018-09-01 00:00:00
abstract：:The purpose of this in vitro study was to observe the morphological changes and apical dye penetration at apical dentin surfaces after apicoectomy with conventional techniques and laser beam. Sixty single-rooted extracted teeth were selected for the study. The crowns were resected below the cemento-enamel junction. Th...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0497-z
更新日期：2008-10-01 00:00:00
abstract：:In an in vitro study, the effect of light polarization on the efficiency of 5-aminolaevulinic acid (ALA) photodynamic therapy (PDT) of basal cell carcinoma (BCC) was investigated. Three states of light polarization (non-polarized, linearly polarized, and circularly polarized) were considered. Cells were exposed to gre...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2369-5
更新日期：2018-02-01 00:00:00
abstract：:Although numerous papers have recently been published on ablative fractional resurfacing, there is a lack of information in literature on very long-term results. The aim of this retrospective study is to evaluate the efficacy, adverse side effects, and long-term results of a random fractional ultrapulsed CO2 laser on ...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-012-1116-1
更新日期：2013-02-01 00:00:00
abstract：:Although ear reconstruction technology has been highly developed in recent years, hair growth on the reconstructed ear has plagued both surgeons and patients. In this paper, the authors introduce a clinical application of intense pulsed light depilation in total auricular reconstruction. From August 2012 to August 201...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-017-2255-1
更新日期：2017-08-01 00:00:00
abstract：:Although some studies claim to the increase of composite resin adhesion to Er:YAG-laser-treated dentin, there are still no reports on the adhesion of composite resin cements to the irradiated surface. This in vitro study evaluated the tensile bond strength (TBS) of a composite resin cement to dentin treated with the E...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-006-0433-7
更新日期：2007-09-01 00:00:00
abstract：:This study aimed to investigate the influence of low-power gallium-aluminium-arsenide (GaAlAs) laser [830 nm, continuous wave (CW), 40 mW and fluence 4 J/cm(2)] on the healing of surgically created bone defects in rats treated with bioactive glass graft material. Surgical bone defects were created in the mandibles of ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0590-y
更新日期：2009-07-01 00:00:00
abstract：:This study assessed the effect of curcumin as a photosensitizer in antimicrobial photodynamic therapy (aPDT) for the treatment of induced periodontitis in rats. Periodontitis was induced via a ligature around the mandibular first molar on the left side of 96 rats. The ligature was removed 7 days later, and the animals...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2261-3
更新日期：2017-11-01 00:00:00
