Abstract:
:In an in vitro study, the effect of light polarization on the efficiency of 5-aminolaevulinic acid (ALA) photodynamic therapy (PDT) of basal cell carcinoma (BCC) was investigated. Three states of light polarization (non-polarized, linearly polarized, and circularly polarized) were considered. Cells were exposed to green (532 pm 20 nm) irradiation from light emitting diodes. Cell survival was measured by the colorimetric assay (WST-1) and Trypan blue staining. The colorimetric assay showed a pronounced decrease in the cell viability (up to 30%) using polarized light compared to the non-polarized one in the wavelength region used. Similar results were obtained by the cell counting method (20-30% increase in cell death). The observed effect was dependent on the concentration of photosensitizer. The effect is more expressed in the case of linearly polarized light compared to the circularly polarized one. Results show that the use of polarized light increases the efficiency of in vitro ALA-PDT of BCC. Utilizing polarized light, it is possible to obtain the same effect from PDT by lower concentrations of photosensitizer. Additionally, the concentration dependency of PDT response and photo-bleaching is also reduced.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
JalalKamali M,Nematollahi-Mahani SN,Shojaei M,Shamsoddini A,Arabpour Ndoi
10.1007/s10103-017-2369-5subject
Has Abstractpub_date
2018-02-01 00:00:00pages
305-313issue
2eissn
0268-8921issn
1435-604Xpii
10.1007/s10103-017-2369-5journal_volume
33pub_type
杂志文章abstract::Photobiomodulation is a treatment that has been widely used in neurotrauma and neurodegenerative diseases. In the present study, low-level laser therapy was administered to patients with spinal cord injury. Twenty-five individuals were divided into two groups: placebo photobiomodulation plus physiotherapy and active p...
journal_title:Lasers in medical science
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journal_title:Lasers in medical science
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abstract::In this study, we compared the microleakage of composite fillings cured with halogen bulb, LED and argon ion laser (488 nm). Twenty-four extracted human molars were divided randomly in three groups. Six cavities were prepared on the coronal part of each tooth. Standard cavities (1.7 x 2 mm) were prepared. Cavities wer...
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journal_title:Lasers in medical science
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journal_title:Lasers in medical science
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journal_title:Lasers in medical science
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journal_title:Lasers in medical science
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journal_title:Lasers in medical science
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journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
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journal_title:Lasers in medical science
pub_type: 杂志文章
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journal_title:Lasers in medical science
pub_type: 杂志文章
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journal_title:Lasers in medical science
pub_type: 杂志文章
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journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
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更新日期:2019-06-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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journal_title:Lasers in medical science
pub_type: 杂志文章
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journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
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journal_title:Lasers in medical science
pub_type: 杂志文章
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journal_title:Lasers in medical science
pub_type: 杂志文章
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pub_type: 临床试验,杂志文章
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journal_title:Lasers in medical science
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journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
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journal_title:Lasers in medical science
pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00
abstract::The aim of this study was to investigate the effect of different working modes (pulsed and micropulsed) and power settings of a standardized 980-nm diode laser on collateral thermal soft-tissue damage. A total of 108 bovine liver samples were cut with a diode laser at various settings in pulsed and micropulsed mode an...
journal_title:Lasers in medical science
pub_type: 杂志文章
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