Character of skin on photo-thermal response and its regeneration process using second-harmonic generation microscopy.

Abstract:

:Quantitative characterization of skin collagen on photo-thermal response and its regeneration process is an important but difficult task. In this study, morphology and spectrum characteristics of collagen during photo-thermal response and its light-induced remodeling process were obtained by second-harmonic generation microscope in vivo. The texture feature of collagen orientation index and fractal dimension was extracted by image processing. The aim of this study is to detect the information hidden in skin texture during the process of photo-thermal response and its regeneration. The quantitative relations between injured collagen and texture feature were established for further analysis of the injured characteristics. Our results show that it is feasible to determine the main impacts of phototherapy on the skin. It is important to understand the process of collagen remodeling after photo-thermal injuries from texture feature.

journal_name

Lasers Med Sci

authors

Wu SL,Li H,Zhang XM,Chen WR,Wang YX

doi

10.1007/s10103-013-1296-3

subject

Has Abstract

pub_date

2014-01-01 00:00:00

pages

141-6

issue

1

eissn

0268-8921

issn

1435-604X

journal_volume

29

pub_type

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