Abstract：
:Acneiform rash associated with epidermal growth factor receptor inhibitors frequently presents facial manifestations. The treatment modality for such lesions still needs to be elucidated. The aim of this original report was to evaluate the effectiveness of high-level laser therapy in reducing the severity of facial acneiform rash induced by cetuximab, an epidermal growth factor receptor inhibitors. Four patients with metastatic colorectal cancer and two patients with head and neck cancer showing cetuximab-induced facial rash were treated by high-level laser therapy in two 8-min-long consecutive sessions/day over a 4-day treatment. Patients wore protective glasses to prevent eye damage related to laser light. Subsequently, patients were seen once a week for up to 21 days and after 180 days. During each day of treatment and each follow-up recall, patients were asked to complete a questionnaire about the onset and progression of their acneiform rash (for a total of eight sessions). Cetuximab-related toxicity and general discomfort visual analogue scales were also recorded in each of these eight sessions in the treated and control areas in each patient. After the fourth session of high-level laser therapy, the patients showed a noteworthy decrease in both cetuximab-related toxicity and visual analogue scales, up to a complete regression of the lesions at the end of the follow-up in all treated areas. The high-level laser therapy was effective in the healing of acneiform rash associated with epidermal growth factor receptor inhibitors with no side effects.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Gobbo M,Ottaviani G,Mustacchi G,Di Lenarda R,Biasotto Mdoi
10.1007/s10103-011-1029-4subject
Has Abstractpub_date
2012-09-01 00:00:00pages
1085-90issue
5eissn
0268-8921issn
1435-604Xjournal_volume
27pub_type
杂志文章abstract：:The aim of this in vitro study was to assess the effect of Er:YAG laser surface treatment on the tensile bond strength of a sealant in permanent teeth. A total of 30 sound third molars were selected and embedded in cold-cure acrylic resin. The enamel surfaces were flattened by a grinding. The teeth were randomly divid...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-010-0869-7
更新日期：2012-03-01 00:00:00
abstract：:The bond strength of resin composite to Er,Cr:YSGG laser-irradiated enamel and dentin has been evaluated in only a few studies. Therefore, we measured and compared the micro-shear bond strength of composite restorations to enamel and dentin using two different cavity-preparation tools and conditioning methods. One hun...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0961-7
更新日期：2012-07-01 00:00:00
abstract：PURPOSE:Acne scarring represents a common problem that negatively impacts patients' quality of life. Different types of treatments are currently available for this dermatological condition. This study evaluates the efficacy of a new 675-nm laser source system on acne scars with the use of established parameters that gu...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03063-6
更新日期：2021-02-01 00:00:00
abstract：:Osteoarthritis (OA) is a chronic joint disease that leads to pain and functional incapacity. The aim of the study is to investigate the effects of the incorporation of photobiomodulation (PBM) (via cluster) into a physical exercise program on the level of pain, lower limb muscle strength, and physical capacity, in pat...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-019-02807-3
更新日期：2020-02-01 00:00:00
abstract：:The effects of He-Ne laser irradiation on erythrocyte hemolysis were studied. Erythrocytes are prone to be easily damaged with hemolysis under laser irradiation. It was found that the power density (PD) of laser irradiation, but not the total irradiation power, is the crucial parameter for the hemolysis. Under irradia...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-004-0320-z
更新日期：2004-01-01 00:00:00
abstract：:Low-level laser therapy (LLLT) has proved to have biostimulating effects on tissues over which they are applied, therefore accelerating the healing process. Most studies in implantology were focused on a reduction of the duration of osseointegration. There exist few articles analyzing the potential effects of these th...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-015-1860-0
更新日期：2016-02-01 00:00:00
abstract：:Recent studies with phototherapy have shown positive results in enhancement of performance and improvement of recovery when applied before exercise. However, several factors still remain unknown such as therapeutic windows, optimal treatment parameters, and effects of combination of different light sources (laser and ...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-014-1611-7
更新日期：2014-11-01 00:00:00
abstract：:The molecular changes in gene expression following ablative laser treatment of skin lesions, such as atrophic scars and UV-damaged skin, are not completely understood. A standardized in vitro model of human skin, to study the effects of laser treatment on human skin, has been recently developed. Therefore, the aim of ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2175-0
更新日期：2017-05-01 00:00:00
abstract：:Since time immemorial, tuberculosis (TB) has intimidated the human race owing to its severity. Its socio-economic burden has led to it being a major cause of concern. It is one of the world's major causes of death from a single agent. Since most of the middle- and low-income countries are burdened with TB, sputum smea...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-019-02947-6
更新日期：2020-08-01 00:00:00
abstract：:The aim of the present study was to evaluate the success rate of failed implants re-implanted after surface treatment with CO2 laser. Despite the widespread use of dental implants, there are many incidents of failures. It is believed that lasers can be applied to decontaminate the implant surface without damaging the ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-1921-z
更新日期：2016-07-01 00:00:00
abstract：:Different ablation techniques have been utilized in the treatment of Barrett's esophagus (BE) to reduce the risk of degeneration. Treatment complications, risk of recurrence, and buried intestinal metaplasia (IM) are all major concerns. The effect of diode laser treatment on BE, studied in a group of patients over a l...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-010-0836-3
更新日期：2011-03-01 00:00:00
abstract：:The traditional needle cricothyroidotomy procedure is performed blindly without any medical equipment. Complications including posterior tracheal wall perforation, accidental vessel puncture, and missed tracheal puncture are reported. Therefore, we proposed a dual-wavelength fiber-optic technique based on the techniqu...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03065-4
更新日期：2020-07-23 00:00:00
abstract：:Previous studies have been suggested that photodynamic therapy (PDT) can be used as an adjuvant treatment for denture stomatitis. In this study, we evaluated the effects of multiple sessions of PDT on Candida glabrata biofilms in specimens of polymerized acrylic resin formed after 5 days. Subsequently, four applicatio...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2147-4
更新日期：2017-04-01 00:00:00
abstract：:Lasers have many favorable features as a light source owing to their monochromaticity and coherence. This study examined the mechanical properties of composite resins that were light-cured using a diode-pumped solid state (DPSS) laser. Eight composite resins were light-cured using four different light sources (one qua...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1117-0
更新日期：2013-02-01 00:00:00
abstract：:The aim of this study was to evaluate the shear bond strength (SBS) of a microhybrid composite resin bonded with three different adhesive systems to Er:YAG laser- (EL) or bur-prepared dentin surfaces and to analyze the quality and ultrastructure of the adhesive-dentin interfaces by scanning electron microscopy (SEM). ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1424-0
更新日期：2015-02-01 00:00:00
abstract：:The objective of this study was to evaluate the microbiological and clinical outcomes following nonsurgical treatment by either scaling and root planing, combination of Nd:YAG and Er:YAG lasers, or by Er:YAG laser treatment alone. The study involved 60 patients with generalized chronic periodontitis, randomly assigned...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-018-2491-z
更新日期：2018-09-01 00:00:00
abstract：:The in vivo photodynamic activities of four poly(ethylene glycol) (PEG) conjugates of the photosensitiser 5,10,15,20-tetrakis-(m-hydroxyphenyl)chlorin (mTHPC, temoporfin, Foscan(®)) were compared with that of mTHPC over a range of drug-light intervals using acute tumour necrosis and skeletal muscles swelling in a mous...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s101030050019
更新日期：1999-03-01 00:00:00
abstract：:The aim of this study was to evaluate the bactericidal effect of ultraviolet (UV) light at 265-nm (UVC) and 310-nm (UVB) wavelengths from a newly developed UV light-emitting diode (LED) device against cariogenic bacteria in vitro. Suspensions of Streptococcus mutans (S. mutans) and Streptococcus sobrinus were directly...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2685-4
更新日期：2019-07-01 00:00:00
abstract：:Nonablative skin rejuvenation using laser, intense pulsed lights (IPLs), or radiofrequency techniques are becoming increasingly popular. In this paper, a novel protocol that integrates IPL sessions, low intense light and vitamin C, low-weight hyaluronic acid, betaglucan dermal injection versus IPL photorejuvenation as...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s10103-007-0456-8
更新日期：2008-04-01 00:00:00
abstract：UNLABELLED:Connective tissue graft (CTG), which is considered to be among the best techniques for treating gingival recession, has presented stable long-term results. However, this technique causes morbidity and discomfort in the palatine region due to graft removal at that site. A previous study reports that photobiom...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-016-1988-6
更新日期：2016-09-01 00:00:00
abstract：:The purpose of this study was to evaluate the acid resistance of erbium:yttrium-aluminum-garnet (Er:YAG) lased sub-surface dentin using a scanning electron microscope (SEM). Dentin disks were exposed to a single pulse of Er:YAG laser irradiation at 80 mJ/pulse under water spray, with the contact sapphire tip vertical ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0553-3
更新日期：2009-07-01 00:00:00
abstract：:The present investigation focuses on understanding the role of photobiomodulation in enhancing tissue proliferation. Circular excision wounds of diameter 1.5 cm were created on Swiss albino mice and treated immediately with 2 J/cm2 and 10 J/cm2 single exposures of the Helium-Neon laser along with sham-irradiated contr...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03202-z
更新日期：2020-11-27 00:00:00
abstract：:A growing number of laboratory and clinical studies over the past 10 years have shown that low-level laser stimulation (633 or 670 nm) at extremely low power densities (about 0.15 mW/cm(2)), when administered through a particular emission mode, is capable of eliciting significant biological effects. Studies on cell cu...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-010-0837-2
更新日期：2011-01-01 00:00:00
abstract：:We report the results of endoscopic laser therapy on 59 patients with upper gastrointestinal vascular ectasia. After 300 sessions, complications were two nonbleeding and three bleeding ulcers, treated successfully with endoscopic therapy. After treatment, blood transfusions were abolished in 61% and reduced in 22% of ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-006-0389-7
更新日期：2006-09-01 00:00:00
abstract：:Photofrin photodynamic therapy (PDT) is a licenced treatment for Barrett's oesophagus (BE) with high-grade dysplasia (HGD) but causes strictures and photosensitivity and complete reversal of dysplasia (CR-HGD) by 50 % at 5 years. 5-Aminolaevulinic acid (ALA) is an alternative treatment with non-randomised data suggest...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-012-1132-1
更新日期：2013-05-01 00:00:00
abstract：:Despite the positive effects of low-level laser therapy (LLLT) on muscle fatigue before exercises using a single muscle group, the acute effects of LLLT on performance in cardiopulmonary exercise testing (CPET) are poorly understood. We aimed to assess the acute effects of LLLT on physiologic and electromyographic res...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-014-1595-3
更新日期：2014-11-01 00:00:00
abstract：:This study analyzed the effects of light-emitting diode (LED) therapy on the morphology of muscle tissue as well as collagen remodeling and matrix metalloproteinase 2 (MMP-2) activity in the skeletal muscle of rats following acute injury. Wistar rats were divided into four groups: (1) control, (2) sham, (3) untreated ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-1888-9
更新日期：2016-04-01 00:00:00
abstract：:The aim of this study was to identify biochemical changes in sciatic nerve (SN) after crush injury and low-level laser therapy (LLLT) with 660 nm and 808 nm by Raman spectroscopy (RS) analysis. A number of 32 Wistar rats were used, divided into four groups (control 1, control 2, LASER 660 nm, and LASER 808 nm). All an...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2627-1
更新日期：2019-04-01 00:00:00
abstract：:Primary hepatocellular carcinoma (HCC) and colon carcinoma are two of the most common clinical malignancies along with high morbidity and mortality. As low-power laser irradiation (LPLI) can induce cytotoxicity or cell apoptosis on several types of hyperplasia, LPLI may be a potential alternative treatment for gastroe...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02869-3
更新日期：2020-04-01 00:00:00
abstract：:Bisphosphonate-related osteonecrosis of the jaw is a well-known potential side effect of long-term bisphosphonate therapy; the primary objective of the treatment should be to improve patient quality of life through pain and infection management, to prevent the development of new lesions, and to slow disease progressio...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-016-1929-4
更新日期：2016-08-01 00:00:00
