Effects of dynamic changes of tissue properties during laser-induced interstitial thermotherapy (LITT).

Abstract:

:A two-dimensional model including the effects of dynamic changes in the physical properties on tissue temperature and damage was developed to describe laser energy transport, heat transfer, and damage accumulation during laser-induced interstitial thermotherapy (LITT). The Monte Carlo method was used to simulate photon transport in a tissue in the nonuniform optical property field, with the finite difference method used to solve the Pennes bioheat equation to calculate the temperature distribution and the Arrhenius equation used to predict the extent of thermal damage. The numerical results showed that the dynamic changes in the optical properties, thermal properties, and blood perfusion rate significantly affected damage volume accumulation and temperature history and should be included in numerical simulations of the LITT treatment.

journal_name

Lasers Med Sci

authors

Jiang SC,Zhang XX

doi

10.1007/s10103-004-0324-8

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

197-202

issue

4

eissn

0268-8921

issn

1435-604X

journal_volume

19

pub_type

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