Abstract：
:The effect of low-level laser therapy (LLLT) on the cardiovascular system is not fully established. Since the endothelium is an important endocrine element, establishing the mechanisms of LLLT action is an important issue.The aim of the study was to evaluate the effect of transdermal LLLT on endothelial function.In this study, healthy volunteers (n = 40, age = 20-40 years) were enrolled. N = 30 (14 female, 16 male, mean age 30 ± 5 years) constituted the laser-irradiated group (LG). The remaining 10 subjects (6 women, 4 men, mean age 28 ± 5 years) constituted the control group (CG). Participants were subjected to LLLT once a day for three consecutive days. Blood for biochemical assessments was drawn before the first irradiation and 24 h after the last session. In the LG, transdermal illumination of radial artery was conducted (a semiconductor laser λ = 808 nm, irradiation 50 mW, energy density 1.6 W/cm(2) and a dose 20 J/day, a total dose of 60 J). Biochemical parameters (reflecting angiogenesis: vascular endothelial growth factor (VEGF), fibroblast growth factor (FGF), angiostatin; antioxidative status: glutathione (GSH) and the nitric oxide metabolic pathway: symmetric dimethylarginine (SDMA), asymmetric dimethylarginine (ADMA) and L-arginine) were assessed. In the LG, a significant increase in GSH levels and considerable decrease in angiostatin concentration following the LLLT were observed. No significant differences in levels of the VEGF, FGF, SDMA, ADMA were observed.LLLT modifies vascular endothelial function by increasing its antioxidant and angiogenic potential. We found no significant differences in levels of the nitric oxide pathway metabolites within 24 h following the LLLT irradiation.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Szymczyszyn A,Doroszko A,Szahidewicz-Krupska E,Rola P,Gutherc R,Jasiczek J,Mazur G,Derkacz Adoi
10.1007/s10103-016-1971-2subject
Has Abstractpub_date
2016-09-01 00:00:00pages
1301-7issue
7eissn
0268-8921issn
1435-604Xpii
10.1007/s10103-016-1971-2journal_volume
31pub_type
临床试验,杂志文章abstract：:Laser beam deflection is a useful tool for studying the dynamics of the pulsed laser ablation mechanism, and has the advantage of being used as an in situ laser damage monitoring technique for both bulk and thin film polymeric and biological tissue samples. This work employs the photothermal deflection technique to st...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/BF02767153
更新日期：1997-12-01 00:00:00
abstract：:We report the results of endoscopic laser therapy on 59 patients with upper gastrointestinal vascular ectasia. After 300 sessions, complications were two nonbleeding and three bleeding ulcers, treated successfully with endoscopic therapy. After treatment, blood transfusions were abolished in 61% and reduced in 22% of ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-006-0389-7
更新日期：2006-09-01 00:00:00
abstract：:The aim of this study is to evaluate the effectiveness of the low-level laser therapy (LLLT) in the control of pain, swelling, and trismus associated with surgical removal of impacted lower third molars. Thirty patients were randomized into two treatment groups, each with 15 patients-group test (LLLT) and a group cont...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-012-1174-4
更新日期：2013-05-01 00:00:00
abstract：:Corrosiveness of enamel surfaces of Smartbleach, Opus White, Opalescense Xtra Boost and a gel containing titanium dioxide (TiO(2)) particles, activated either by a frequency doubled neodymium: yttrium-aluminum-garnet (Nd:YAG) laser (532 nm) or a diode laser (810 nm) was evaluated by environmental scanning electron mic...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0567-x
更新日期：2009-05-01 00:00:00
abstract：:Inflammation of synovial membrane and degeneration of articular cartilage in osteoarthritis (OA) lead to major changes in joint space width (JSW) and biochemical components such as collagen-II telopeptide (CTX-II) and matrix metallo protineases (MMP-3, 8, and 13). Low-level laser therapy (LLLT) is thought to have an a...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-016-2114-5
更新日期：2017-02-01 00:00:00
abstract：:A novel skin phantom is described that is constructed with quantifiable amounts of skin pigments, as well as a light scattering medium in the form of barium sulphate suspension. The two predominant skin pigments (melanin and haemoglobin) are varied in controlled amounts within the phantoms to simulate skin colour in d...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0495-1
更新日期：2008-10-01 00:00:00
abstract：:We aimed at examining the effects of a percentage of air/water in spray on the cutting efficiency of Er,Cr:YSGG laser for enamel and dentin. The intensity and frequency of irradiation were 3.0 W and 20 Hz for the enamel surface and 2.0 W and 20 Hz for the dentin surface, respectively. Flattened surfaces of enamel and ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2607-5
更新日期：2019-02-01 00:00:00
abstract：:Previous in vivo and in vitro studies have reported that low-level diode laser therapy induces a biostimulatory effect, such as cell proliferation. The aim of the present study was to evaluate whether the laser irradiation of osteoblast-like cells (MG-63) can modify alkaline phosphatase activity (ALP), antigenic profi...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-014-1557-9
更新日期：2014-07-01 00:00:00
abstract：:Laser therapy is able to modulate cell metabolism and accelerate the repair of fracture. Little attention has been given to the effect of laser on bone with osteopenia or osteoporosis. The purpose of our study was to verify the effect of laser therapy in combination with bisphosphonate on osteopenic bone structure. Th...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0568-9
更新日期：2009-05-01 00:00:00
abstract：:Recent studies have investigated whether low level laser therapy (LLLT) can optimize human muscle performance in physical exercise. This study tested the effect of LLLT on muscle performance in physical strength training in humans compared with strength training only. The study involved 36 men (20.8±2.2 years old), cl...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-010-0855-0
更新日期：2011-05-01 00:00:00
abstract：:The bactericidal activity of a pulsed fibre-optic Nd-YAP laser on various strains of oral bacteria: Prevotella nigrescens, Streptococcus sanguis, Actinomyces viscosus (i), Fusobacterium nucleatum, Actinobacillus actinomycetemcomitans and Peptostreptococcus micros (i) was evaluated. A 200-μm optical fibre was placed in...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s101030050010
更新日期：1998-12-01 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2289-4
更新日期：2017-09-01 00:00:00
abstract：:Biostimulatory effect of cell proliferation and bone formation by laser irradiation has been reported, however, very little is known about the molecular basis of mechanisms. We previously constructed the cDNA library of mouse osteoblastic cells (MC3T3-E1) which enhanced gene expression by laser irradiation using a sub...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/pl00011357
更新日期：2001-01-01 00:00:00
abstract：:Delivery of intradermally focused nanosecond laser pulses with small energy as an alternate technique applicable to clinical procedures in dermatological and plastic surgery is an area of relatively new interest with multiple potential applications. We assessed this approach on common tattoo pigments in dermis in an i...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s101030200025
更新日期：2002-01-01 00:00:00
abstract：:Photodynamic therapy (PDT) with photosensitizer is one of the promising modalities for cancer treatment. For clinical use of PDT, screening process should be preceded to enhance sensitivity to PDT. Thus, we investigated a molecular biomarker to determine the sensitivity to pheophorbide a (Pa)-PDT in immortalized human...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1350-1
更新日期：2015-02-01 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-015-1851-1
更新日期：2016-02-01 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03225-6
更新日期：2021-01-07 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章
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更新日期：2003-01-01 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2323-6
更新日期：2018-01-01 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章
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更新日期：2020-11-27 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章
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更新日期：2006-04-01 00:00:00
abstract：:The purpose of this study is to evaluate microtensile bond strength (μTBS) of an etch-and-rinse adhesive to enamel and dentin after treatment with Er:YAG laser using different pulse durations. Extracted human molars were flattened to obtain enamel or dentin surfaces. The enamel specimens (E) were divided into nine gro...
journal_title：Lasers in medical science
pub_type： 杂志文章
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更新日期：2012-01-01 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章
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更新日期：2004-01-01 00:00:00
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journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
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更新日期：2012-01-01 00:00:00
abstract：:A limited number of studies have evaluated the efficacy and safety of electrode pin fractional radiofrequency (FRF) for periorbital wrinkle treatment in Asian patients, but none have measured noninvasive methodological objective parameters such as periorbital wrinkle area. This study aimed to investigate the efficacy ...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
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更新日期：2017-01-01 00:00:00
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journal_title：Lasers in medical science
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journal_title：Lasers in medical science
pub_type： 杂志文章
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journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
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journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0951-9
更新日期：2011-11-01 00:00:00
abstract：:Compensatory hypertrophy (CH) occurs due to excessive mechanical load on a muscle, promoting an increase in the size of muscle fibers. In clinical practice, situations such as partial nerve injuries, denervation, and muscle imbalance caused by trauma to muscles and nerves or diseases that promote the loss of nerve con...
journal_title：Lasers in medical science
pub_type： 杂志文章
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