Abstract：
:Minimal hepatic encephalopathy (MHE) has been shown to affect daily functioning, quality of life, driving and overall mortality. However, little is known about treating or diagnosing early impairments involved in MHE. We studied one of its precipitating factors, portal hypertension. The purpose was to evaluate an enhancement in neuronal metabolism through low-light-level therapy (LLLT) and whether this therapy has effects on behavioural task acquisition. Rats were trained to perform a stimulus-response task using the Morris water maze. Three groups of animals were used: a SHAM (sham-operated) group (n = 7), a portal hypertension (PH) group (n = 7) and a PH + LLLT group (n = 7). The triple portal vein ligation method was used to create an animal model of the early developmental phase of HE, and then the animals were exposed to 670 + 10 nm LED light at a dose of 9 J/cm2 once a day for 7 days. The metabolic activity of the brains was studied with cytochrome c oxidase histochemistry. There were differences in behavioural performance, with an improvement in the PH + LLLT group. Energetic brain metabolism revealed significant differences between the groups in all the brain structures analysed, except the anterodorsal thalamus. At the same time, in different brain networks, the PH group showed a more complicated relationship among the structures, while the SHAM and PH + LLLT groups had similar patterns. In this study, we provide the first preliminary insights into the validity of LLLT as a possible intervention to improve memory under minimal hepatic encephalopathy conditions.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Arias N,Méndez M,Arias JLdoi
10.1007/s10103-016-2042-4subject
Has Abstractpub_date
2016-11-01 00:00:00pages
1717-1726issue
8eissn
0268-8921issn
1435-604Xpii
10.1007/s10103-016-2042-4journal_volume
31pub_type
杂志文章abstract：:The molecular changes in gene expression following ablative laser treatment of skin lesions, such as atrophic scars and UV-damaged skin, are not completely understood. A standardized in vitro model of human skin, to study the effects of laser treatment on human skin, has been recently developed. Therefore, the aim of ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2175-0
更新日期：2017-05-01 00:00:00
abstract：:Physical stimulation of body surface points is known to affect various organ functions. In traditional Chinese medicine, so-called acupoints were defined. These points can be physically stimulated to effectively treat various diseases. Here we describe for the first time the effect of CO(2) laser stimulation at the ac...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0973-3
更新日期：2012-03-01 00:00:00
abstract：:The aim of this work is to analyze the effects of LED therapy at 940 nm or cold water immersion therapy (CWI) after an acute bout of exercise on markers of muscle damage and inflammation. Thirty-two male Wistar rats were allocated into four groups: animals kept at rest (control), exercised animals (E), exercised + CWI...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-1039-2
更新日期：2012-09-01 00:00:00
abstract：:The aim of the present study was to evaluate the antimicrobial effect of antimicrobial photodynamic therapy (aPDT) in alveolar treatment of areas with induced periodontitis. Thirty male Wistar rats were subjected to ligature-induced periodontal disease (PD) in the first left inferior molars, while the right side molar...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1400-8
更新日期：2015-02-01 00:00:00
abstract：:This study compares sensitivity reduction after dental restoration with and without prior diode laser (DL) irradiation for cervical dentine hypersensitivity (CDH) from non-carious cervical lesions (NCCLs) unresponsive to desensitizing agents. Eighty-eight teeth of 28 subjects (21 females; age 23-64 years), with CDH fr...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-016-2087-4
更新日期：2017-01-01 00:00:00
abstract：:Precise nerve localization is of major importance in both surgery and regional anesthesia. Optically based techniques can identify tissue through differences in optical properties, like absorption and scattering. The aim of this study was to evaluate the potential of optical spectroscopy (diffuse reflectance spectrosc...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2433-1
更新日期：2018-04-01 00:00:00
abstract：:To evaluate the effect of various media and Iridex MicroPulse P3 (MP3) probe angles on the power output from the Cyclo G6 Glaucoma Laser (G6) System. A laser power meter was used to measure the power output (milliwatts, mW) of the Cyclo G6 System. Each of the ten trials consisted of measurements in six different media...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03089-w
更新日期：2020-07-18 00:00:00
abstract：:Neuropathic pain (NP) is caused by damage to the nervous system due to reactive oxygen spices (ROS) increase, antioxidants reduction, ATP production imbalance, and induction of apoptosis. In this investigation, we applied low-level laser 660 nm (photobiomodulation therapy) as a new strategy to modulate pain. In order ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-2062-0
更新日期：2016-12-01 00:00:00
abstract：:Bacterial biofilms are often found in chronically infected wounds. Biofilms protect bacteria from antibiotics and impair wound healing. Surgical debridement is often needed to remove the biofilm from an infected wound. Laser-generated shockwave (LGS) treatment is a novel tissue-sparing treatment for biofilm disruption...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03171-3
更新日期：2020-10-27 00:00:00
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journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-016-2136-z
更新日期：2017-02-01 00:00:00
abstract：:The aim of the study was to investigate the effect of low-level 809 nm laser irradiation on the proliferation rate of human larynx carcinoma cells in vitro. Epithelial tumor cells were obtained from a laryngeal carcinoma and cultured under standard conditions. For laser treatment the cells were spread on 96-well tissu...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-003-0265-7
更新日期：2003-01-01 00:00:00
abstract：:The laser source with 3 μm/2 μm output wavelength has many application prospects in clinical medicine, photoelectric countermeasure, and scientific research measurement. An Er3+ doped ZBLAN fiber laser with output wavelength of 2 .8 μm and 1 .6 μm is experimentally studied. By setting the pump power to 5 W, a continuo...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02766-9
更新日期：2019-10-01 00:00:00
abstract：:The erbium:YSGG and erbium:YAG lasers are used for tissue ablation in dermatology, dentistry and ophthalmology. The purpose of this study was to compare germanium oxide and sapphire optical fibres for transmission of sufficient Q-switched erbium laser pulse energies for potential use in both soft and hard tissue ablat...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-004-0316-8
更新日期：2004-01-01 00:00:00
abstract：:Reepithelialization and wound closure are the desired outcome for several ulcerative conditions. Such resolution reduces the possibility of wound contamination and maintenance of the injury and improves the reestablishment of tissue morphology and functions. Investigators are seeking adjuvant therapies that can accele...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2176-z
更新日期：2018-02-01 00:00:00
abstract：:The main goal of anti-cancer therapeutic approaches is to induce apoptosis in tumor masses but not in the normal tissues. Nevertheless, the combination of photodynamic irradiation with complementary oncostatic agents contributes to better therapeutic performance. Here, we applied two different cell lines; SKOV3 ovaria...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-2016-6
更新日期：2016-11-01 00:00:00
abstract：:Wound healing is a very complex process, some phases of which have only recently been explained. Magnetic and electromagnetic fields can modulate this process in a non-thermal way. The aim of this research was to compare the influence of constant and pulsed electromagnetic fields and low-level laser therapy (LLLT) on ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0564-0
更新日期：2009-05-01 00:00:00
abstract：:Oxygen consumption at the targeted site has a significant effect on dosimetry in photodynamic therapy (PDT). However, oxygen consumption in PDT using a pulsed laser as a light source has not been clarified. We therefore investigated the dependence of cytotoxicity on the oxygen consumption and the photosensitizer photo...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-004-0288-8
更新日期：2004-01-01 00:00:00
abstract：:Antimicrobial photodynamic therapy (APDT) combined with endodontic treatment has been recognized as an alternative approach to complement conventional root canal disinfection methods on bacterial biofilms. We developed an in vitro model of bioluminescent Candida albicans biofilm inside curved dental root canals and i...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-014-1629-x
更新日期：2015-08-01 00:00:00
abstract：:Recently, investigations suggest the benefits of low-level laser (light) therapy (LLLT) in noninvasive treatment of cellulite, improvement of body countering, and control of lipid profile. However, the underlying key mechanism for such potential effects associated to aerobic plus resistance training to reduce body fat...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-015-1759-9
更新日期：2015-07-01 00:00:00
abstract：:The aim of this study was to evaluate the degree of conversion (DC) and to identify the viscoelastic properties: storage modulus (E'), loss modulus (E"), tangent delta (tan δ), and glass transition temperature (T g ) of a microhybrid resin-composite light-activated by three different protocols. A Filtek Z250 (3 M ESPE...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-014-1572-x
更新日期：2015-05-01 00:00:00
abstract：:Low-level laser therapy (LLLT) induces anti-inflammatory and angiogenic activities in wound healing. However, the mechanism of action and optimal parameters require further clarification. In this study, we investigated the effects of LLLT on wound healing matrix metalloproteinase (MMP)-2 immunoexpression and angiogeni...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-2080-y
更新日期：2017-01-01 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0489-z
更新日期：2008-07-01 00:00:00
abstract：:Liquid-assisted hard tissue ablation by infrared lasers has extensive clinical application. However, detailed studies are still needed to explore the underlying mechanism. In the present study, the dynamic process of bubble evolution induced by Ho:YAG laser under water without and with bone tissue at different thickne...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-1931-x
更新日期：2016-07-01 00:00:00
abstract：:Treatment of disseminated superficial actinic porokeratosis (DSAP) is poorly standardized. The present review seeks to comprehensively discuss the potential for laser and light modalities in the treatment of DSAP. A systematic review of light and laser treatment modalities was conducted to include 26 cases of patients...
journal_title：Lasers in medical science
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s10103-017-2179-9
更新日期：2017-05-01 00:00:00
abstract：:Facial vitiligo has considerable psychological and emotional impacts. Though topical corticosteroids are the mainstay treatment, adverse reactions are a concern for prolonged use. Additionally, 308-nm excimer lamps have been widely used in vitiligo. This study aimed to assess the effectiveness of a combined 308-nm exc...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-020-03048-5
更新日期：2020-12-01 00:00:00
abstract：:Epithelial cells play an important role in reparative events. Therefore, therapies that can stimulate the proliferation and metabolism of these cells could accelerate the healing process. To evaluate the effects of low-level laser therapy (LLLT), human keratinocytes were irradiated with an InGaAsP diode laser prototyp...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1057-8
更新日期：2013-02-01 00:00:00
abstract：:This ablation rate study has been carried out with a fibre-deliverable, 308 nm, XeCl laser, producing long pulses of 200 ns as opposed to the usual 10-20 ns. This in-depth study aimed to evaluate the ablation rates for this longer pulse length. The effects on the ablation depth of dentine, enamel, soft tissue and bone...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-004-0315-9
更新日期：2004-01-01 00:00:00
abstract：:To evaluate the efficacy of laser fibrotomy in patients with oral submucous fibrosis (OSMF) and also to correlate the habit variables causing OSMF. Thirty patients diagnosed clinically and histopathologically with OSMF were included in the study. Laser fibrotomy was done under local anesthesia using Zolar diode laser ...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-018-2531-8
更新日期：2018-11-01 00:00:00
abstract：:Outpatient laser ablation of palatine tonsils is a very interesting procedure that has been recently introduced as a routine in head and neck surgery departments. The aim of this study was to describe a new strategy using a Doppler-guided fibre optic neodymium-yttrium-aluminium-garnet (YAG) laser to remove up to 80 % ...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-012-1140-1
更新日期：2013-05-01 00:00:00
abstract：:Although some studies claim to the increase of composite resin adhesion to Er:YAG-laser-treated dentin, there are still no reports on the adhesion of composite resin cements to the irradiated surface. This in vitro study evaluated the tensile bond strength (TBS) of a composite resin cement to dentin treated with the E...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-006-0433-7
更新日期：2007-09-01 00:00:00
