Abstract：
:Precise nerve localization is of major importance in both surgery and regional anesthesia. Optically based techniques can identify tissue through differences in optical properties, like absorption and scattering. The aim of this study was to evaluate the potential of optical spectroscopy (diffuse reflectance spectroscopy) for clinical nerve identification in vivo. Eighteen patients (8 male, 10 female, age 53 ± 13 years) undergoing inguinal lymph node resection or resection or a soft tissue tumor in the groin were included to measure the femoral or sciatic nerve and the surrounding tissues. In vivo optical measurements were performed using Diffuse Reflectance Spectroscopy (400-1600 nm) on nerve, near nerve adipose tissue, muscle, and subcutaneous fat using a needle-shaped probe. Model-based analyses were used to derive verified quantitative parameters as concentrations of optical absorbers and several parameters describing scattering. A total of 628 optical spectra were recorded. Measured spectra reveal noticeable tissue specific characteristics. Optical absorption of water, fat, and oxy- and deoxyhemoglobin was manifested in the measured spectra. The parameters water and fat content showed significant differences (P < 0.005) between nerve and all surrounding tissues. Classification using k-Nearest Neighbor based on the derived parameters revealed a sensitivity of 85% and a specificity of 79%, for identifying nerve from surrounding tissues. Diffuse Reflectance Spectroscopy identifies peripheral nerve bundles. The differences found between tissue groups are assignable to the tissue composition and structure.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Langhout GC,Kuhlmann KFD,Wouters MWJM,van der Hage JA,van Coevorden F,Müller M,Bydlon TM,Sterenborg HJCM,Hendriks BHW,Ruers TJMdoi
10.1007/s10103-017-2433-1subject
Has Abstractpub_date
2018-04-01 00:00:00pages
619-625issue
3eissn
0268-8921issn
1435-604Xpii
10.1007/s10103-017-2433-1journal_volume
33pub_type
杂志文章abstract：:The purposes of the study were to evaluate the bond strength of bioceramic TotalFill root repair material (RRM) in retrograde cavities prepared using Er:YAG and Er,Cr:YSGG laser and steel bur, and to analyze failure modes. The root canals of 30 single-rooted teeth were endodontically treated, their root-ends were rese...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02835-z
更新日期：2020-02-01 00:00:00
abstract：:The objective of this study was to evaluate the microbiological and clinical outcomes following nonsurgical treatment by either scaling and root planing, combination of Nd:YAG and Er:YAG lasers, or by Er:YAG laser treatment alone. The study involved 60 patients with generalized chronic periodontitis, randomly assigned...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-018-2491-z
更新日期：2018-09-01 00:00:00
abstract：:Laser excision has been used with increasing success to treat oral leukoplakia. The aim of the present study was to evaluate whether clinical healing of a leukoplakia after laser surgery is associated with a normal functional status of the new epithelium and whether pathological alterations in these parameters are rel...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-011-0941-y
更新日期：2012-01-01 00:00:00
abstract：:The present work evaluated the effects of LED light irradiation on the healing of the navels of neonatal dairy calves. Fifty-seven neonatal calves were divided into two groups. Animals had their umbilical stumps immersed in 10% iodine tincture for 60 s, and this process was repeated every 24 h for three consecutive da...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2283-x
更新日期：2017-09-01 00:00:00
abstract：:Nitrogen laser-induced fluorescence (LIF) and tungsten halogen lamp excited diffuse reflectance spectra were recorded in 350- to 700-nm range on a miniature fiber-optic spectrometer from in vitro premolar tooth during various stages of artificial erosion with 36% phosphoric acid. Both the LIF spectral intensity and th...
journal_title：Lasers in medical science
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abstract：:Down syndrome (DS) has characteristics that include mental retardation, a characteristic phenotype, congenital heart defects, immune disorders, and increased risk of periodontal disease (PD). Antimicrobial photodynamic therapy (aPDT) is the combined use of photosensitizers associated with low-level laser (LLL) and oxy...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-016-2020-x
更新日期：2016-12-01 00:00:00
abstract：:The aim of this study was to compare the rate of tooth displacement, quantity of root resorption, and alveolar bone changes in five groups: corticopuncture (CP), low-level laser therapy (LLLT), CP combined with LLLT (CP + LLLT), control (C), and negative control (NC). A total of 60 half-maxilla from 30 male Wistar rat...
journal_title：Lasers in medical science
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更新日期：2018-05-01 00:00:00
abstract：:Dermatosis papulosa nigra (DPN) is a common condition of pigmented skin. Whilst lesions are benign, they may be symptomatic or cosmetically disfiguring. Ablative lasers have previously been reported as a useful therapeutic modality in DPN. We report the largest case series to date of patients with DPN ablated with the...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-1906-y
更新日期：2016-04-01 00:00:00
abstract：:Infrared laser therapy is used for skeletal muscle repair based on its biostimulative effect on satellite cells. However, shortening of telomere length limits regenerative potential in satellite cells, which occurs after each cell division cycle. Also, laser therapy could be more effective on non-physiologic tissues. ...
journal_title：Lasers in medical science
pub_type： 杂志文章
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更新日期：2016-08-01 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03211-y
更新日期：2021-01-07 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章
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更新日期：2008-10-01 00:00:00
abstract：:Both high-intensity ultraviolet and narrowband ultraviolet B (NB-UVB) are important therapeutic options for vitiligo management, but high-intensity ultraviolet is more effective than NB-UVB. However, the underlying mechanisms have not been well investigated. Herein, we compare the effects of high-intensity ultraviolet...
journal_title：Lasers in medical science
pub_type： 杂志文章
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更新日期：2014-09-01 00:00:00
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journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-012-1140-1
更新日期：2013-05-01 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0451-0
更新日期：2008-01-01 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
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更新日期：2021-02-01 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0909-y
更新日期：2012-03-01 00:00:00
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journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
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更新日期：2014-01-01 00:00:00
abstract：:Since time immemorial, tuberculosis (TB) has intimidated the human race owing to its severity. Its socio-economic burden has led to it being a major cause of concern. It is one of the world's major causes of death from a single agent. Since most of the middle- and low-income countries are burdened with TB, sputum smea...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
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journal_title：Lasers in medical science
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journal_title：Lasers in medical science
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journal_title：Lasers in medical science
pub_type： 杂志文章
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更新日期：2004-01-01 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
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更新日期：2014-11-01 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章,评审
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更新日期：2021-01-03 00:00:00
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journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0567-x
更新日期：2009-05-01 00:00:00
abstract：:This study aimed to compare the effects of photobiomodulation (PBM) in different energy densities and irradiances on maintaining cell viability, and proliferation of pulp fibroblasts from human primary teeth (HPF) were cultured in DMEM and used between the fourth and eighth passages. Then, HPF were irradiated with the...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2301-z
更新日期：2017-09-01 00:00:00
abstract：:The optical properties of the skin (absorption coefficient, scattering coefficient, refractive index) may serve to characterize the skin and are important for correct light dosimetry in many optical diagnostic procedures and laser treatments especially photodynamic therapy and laser therapy. We determined in vivo the ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-009-0725-9
更新日期：2010-03-01 00:00:00
abstract：:The purpose of this study was to compare the effectiveness of 1470- and 980-nm lasers with regard to power output, complications, recanalization rates, and treatment response. We prospectively evaluated the effectiveness of endovenous laser ablation (EVLA) in a total of 152 great and small saphenous veins from 96 pati...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-015-1768-8
更新日期：2015-07-01 00:00:00
abstract：:Biostimulatory effect of cell proliferation and bone formation by laser irradiation has been reported, however, very little is known about the molecular basis of mechanisms. We previously constructed the cDNA library of mouse osteoblastic cells (MC3T3-E1) which enhanced gene expression by laser irradiation using a sub...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/pl00011357
更新日期：2001-01-01 00:00:00
abstract：:Laser angioplasty has been evaluated for coronary applications since the early 1980s. Early complications of dissection, perforation and thermal injury led to a loss of enthusiasm for this technique. Recent advances in catheter development, including optimally spaced laser fibres, athermic 308 nm wave-length catheters...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/pl00011338
更新日期：2001-01-01 00:00:00
abstract：:In periodontal therapy, the use of low-level diode lasers has recently been considered to improve wound healing of the gingival tissue. However, its effects on human gingival epithelial cells (HGECs) remain unknown. The aim of the present study was to examine whether high-frequency low-level diode laser irradiation st...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1292-7
更新日期：2014-07-01 00:00:00
