Abstract：
:Dermatosis papulosa nigra (DPN) is a common condition of pigmented skin. Whilst lesions are benign, they may be symptomatic or cosmetically disfiguring. Ablative lasers have previously been reported as a useful therapeutic modality in DPN. We report the largest case series to date of patients with DPN ablated with the carbon dioxide (CO2) laser. A retrospective case note review was conducted of all patients with DPN treated in our laser clinic in the last five years, and a post-treatment telephone survey was undertaken to assess patient satisfaction. Forty-five patients were identified, with a median age of 41 years (range 25-74 years), of whom 37 (82%) were female. The median number of treatments undertaken was three (range 1-10). Of the 18 respondents to the telephone survey, when asked to grade their satisfaction with the procedure out of 10, median response was 9.5 (range 6-10) with nine patients citing the maximum score of 10. All patients replied that their confidence had improved following the procedure and that they would recommend the treatment to other patients. Five respondents (28%) reported recurrence of a few lesions following CO2 laser ablation; the remaining 13 respondents (72%) reported no recurrence of DPN. No respondents reported any other post-procedural complications (including scarring, hypopigmentation and hyperpigmentation). We advocate use of the CO2 laser as a safe, convenient means of treating DPN, with a high degree of patient satisfaction, low recurrence rate and few complications.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Ali FR,Bakkour W,Ferguson JE,Madan Vdoi
10.1007/s10103-016-1906-ysubject
Has Abstractpub_date
2016-04-01 00:00:00pages
593-5issue
3eissn
0268-8921issn
1435-604Xpii
10.1007/s10103-016-1906-yjournal_volume
31pub_type
杂志文章abstract：:This retrospective case-control study aimed to compare 30 versus 40 W power of CO2 laser for the therapy of genitourinary syndrome of menopause (GSM). Postmenopausal women with severe intensity of dyspareunia and dryness were eligible to be included in this study. Primary outcomes were dyspareunia and dryness. Seconda...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2293-8
更新日期：2017-11-01 00:00:00
abstract：:The aim of this study was to evaluate the shear bond strength (SBS) of a microhybrid composite resin bonded with three different adhesive systems to Er:YAG laser- (EL) or bur-prepared dentin surfaces and to analyze the quality and ultrastructure of the adhesive-dentin interfaces by scanning electron microscopy (SEM). ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1424-0
更新日期：2015-02-01 00:00:00
abstract：:Facial vitiligo has considerable psychological and emotional impacts. Though topical corticosteroids are the mainstay treatment, adverse reactions are a concern for prolonged use. Additionally, 308-nm excimer lamps have been widely used in vitiligo. This study aimed to assess the effectiveness of a combined 308-nm exc...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-020-03048-5
更新日期：2020-12-01 00:00:00
abstract：:The published online version contains mistake. Warren S. Warren was not included in the author group section. Corrected author group section is shown above. ...
journal_title：Lasers in medical science
pub_type： 杂志文章,已发布勘误
doi：10.1007/s10103-017-2339-y
更新日期：2017-12-01 00:00:00
abstract：:Oxygen consumption at the targeted site has a significant effect on dosimetry in photodynamic therapy (PDT). However, oxygen consumption in PDT using a pulsed laser as a light source has not been clarified. We therefore investigated the dependence of cytotoxicity on the oxygen consumption and the photosensitizer photo...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-004-0288-8
更新日期：2004-01-01 00:00:00
abstract：:5-aminolevulinic acid-mediated photodynamic therapy (ALA-PDT) provides a novel and promising treatment for esophageal cancer. However, its specific mechanism has not been fully elucidated and its efficacy is remarkably varied. This study investigated the effect of ALA-PDT on esophageal squamous carcinoma cell line Eca...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-010-0810-0
更新日期：2011-01-01 00:00:00
abstract：:The aims of this study were to evaluate the effects of Photogem®-mediated photosensitization on rat palatal mucosa and the biodistribution of the photosensitizer in this tissue. A solution of Photogem® (500 or 1000 mg/l) was applied to the palatal mucosa for 30 min and the exposure time to blue LED (460 nm) was 20 min...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0909-y
更新日期：2012-03-01 00:00:00
abstract：:Recurrent herpes labialis is a worldwide life-long oral health problem that remains unsolved. It affects approximately one third of the world population and causes frequent pain and discomfort episodes, as well as social restriction due to its compromise of esthetic features. In addition, the available antiviral drugs...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-013-1311-8
更新日期：2014-07-01 00:00:00
abstract：:A two-dimensional model including the effects of dynamic changes in the physical properties on tissue temperature and damage was developed to describe laser energy transport, heat transfer, and damage accumulation during laser-induced interstitial thermotherapy (LITT). The Monte Carlo method was used to simulate photo...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-004-0324-8
更新日期：2005-01-01 00:00:00
abstract：:Photodynamic therapy (PDT) with photosensitizer is one of the promising modalities for cancer treatment. For clinical use of PDT, screening process should be preceded to enhance sensitivity to PDT. Thus, we investigated a molecular biomarker to determine the sensitivity to pheophorbide a (Pa)-PDT in immortalized human...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1350-1
更新日期：2015-02-01 00:00:00
abstract：:Bothropic venom contains a range of biologically active substances capable of causing severe local and systemic envenoming symptomatology within its victims. The snake anti-venom is effective against systemic effects but has no neutralizing effect against the fast developing local effects. Herein, mice gastrocnemius i...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2252-4
更新日期：2017-08-01 00:00:00
abstract：PURPOSE:Acne scarring represents a common problem that negatively impacts patients' quality of life. Different types of treatments are currently available for this dermatological condition. This study evaluates the efficacy of a new 675-nm laser source system on acne scars with the use of established parameters that gu...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03063-6
更新日期：2021-02-01 00:00:00
abstract：:The aim of this study was to evaluate the effect of cavity preparation with Er:YAG laser on dentin adjacent to restorations submitted to cariogenic challenge in situ, by subsuperficial microhardness analysis. Bovine incisors were sectioned, flattened, and polished, resulting in 40 dentin slabs. The slabs were randomly...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-016-2136-z
更新日期：2017-02-01 00:00:00
abstract：:Laser therapy is able to modulate cell metabolism and accelerate the repair of fracture. Little attention has been given to the effect of laser on bone with osteopenia or osteoporosis. The purpose of our study was to verify the effect of laser therapy in combination with bisphosphonate on osteopenic bone structure. Th...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0568-9
更新日期：2009-05-01 00:00:00
abstract：:The objective of this study was to evaluate the safety and efficacy of flexible ureteroscopy (FURS) and holmium:YAG laser lithotripsy for the treatment of upper urinary tract stones in patients on active oral anticoagulants. The records of 1081 patients who underwent flexible ureteroscopic holmium:YAG (Ho:YAG) laser l...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2289-4
更新日期：2017-09-01 00:00:00
abstract：:According to the standard Arrhenius relation, tissue damage is linearly dependent on the duration of exposure to elevated temperatures and exponentially dependent on the temperature itself. However, recently published measurements of damage threshold temperatures at extremely short exposure times (commonly present dur...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-02704-1
更新日期：2019-08-01 00:00:00
abstract：:Photofrin photodynamic therapy (PDT) is a licenced treatment for Barrett's oesophagus (BE) with high-grade dysplasia (HGD) but causes strictures and photosensitivity and complete reversal of dysplasia (CR-HGD) by 50 % at 5 years. 5-Aminolaevulinic acid (ALA) is an alternative treatment with non-randomised data suggest...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-012-1132-1
更新日期：2013-05-01 00:00:00
abstract：:The purposes of the study were to evaluate the bond strength of bioceramic TotalFill root repair material (RRM) in retrograde cavities prepared using Er:YAG and Er,Cr:YSGG laser and steel bur, and to analyze failure modes. The root canals of 30 single-rooted teeth were endodontically treated, their root-ends were rese...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02835-z
更新日期：2020-02-01 00:00:00
abstract：:The present work reports the photo-biomodulatory effect of red (632.8 nm) and near infrared (785 and 830 nm) lasers on burn injury in Swiss albino mice. Animals were induced with a 15-mm full thickness burn injury and irradiated with various fluences (1, 2, 3, 4, and 6 J/cm2) of each laser wavelength under study havin...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-2044-2
更新日期：2016-12-01 00:00:00
abstract：:Low-power laser therapy has become popular in clinical applications including promoting wound healing and pain relief. However, effects of this photoradiation on human hepatoma cells are rarely studied. Previously, we found 808 nm gallium aluminum arsenide (GaAlAs) continuous wave laser had an inhibitory effect on the...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-005-0369-3
更新日期：2006-04-01 00:00:00
abstract：:Interstitial laser Doppler flowmetry was used to measure the effect of interstitial laser-induced thermotherapy on local blood perfusion in normal rat liver in the peripheral treatment region elevated to hyperthermic temperatures. The Nd:YAG laser emitting at 1064 nm was utilised as heat generation source. The plane-c...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s101030050036
更新日期：1999-06-01 00:00:00
abstract：:We evaluated functional and morphological changes after trans-tympanic laser application using several different powers of photobiomodulation (PBM). The left (L) ears of 17 rats were irradiated for 30 min daily over 14 days using a power density of 909.1 (group A, 5040 J), 1136.4 (group B, 6300 J), and 1363.6 (group C...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-015-1851-1
更新日期：2016-02-01 00:00:00
abstract：:Reepithelialization and wound closure are the desired outcome for several ulcerative conditions. Such resolution reduces the possibility of wound contamination and maintenance of the injury and improves the reestablishment of tissue morphology and functions. Investigators are seeking adjuvant therapies that can accele...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-017-2176-z
更新日期：2018-02-01 00:00:00
abstract：:Bacterial biofilms are often found in chronically infected wounds. Biofilms protect bacteria from antibiotics and impair wound healing. Surgical debridement is often needed to remove the biofilm from an infected wound. Laser-generated shockwave (LGS) treatment is a novel tissue-sparing treatment for biofilm disruption...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03171-3
更新日期：2020-10-27 00:00:00
abstract：:A growing number of laboratory and clinical studies over the past 10 years have shown that low-level laser stimulation (633 or 670 nm) at extremely low power densities (about 0.15 mW/cm(2)), when administered through a particular emission mode, is capable of eliciting significant biological effects. Studies on cell cu...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-010-0837-2
更新日期：2011-01-01 00:00:00
abstract：:The authors tested the diagnostic potential of the portable autofluorescence optical system that was developed in the preoperative evaluation of resection margins, and thus of the resection line safety in patients with low-positioned colorectal carcinoma. A total of 217 spectral measurements of the fluorescence proper...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-010-0847-0
更新日期：2011-05-01 00:00:00
abstract：:This study aimed to investigate the influence of low-power gallium-aluminium-arsenide (GaAlAs) laser [830 nm, continuous wave (CW), 40 mW and fluence 4 J/cm(2)] on the healing of surgically created bone defects in rats treated with bioactive glass graft material. Surgical bone defects were created in the mandibles of ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-008-0590-y
更新日期：2009-07-01 00:00:00
abstract：:Cancer treatment with chemotherapy or radiotherapy is associated with some side effects including in the oral cavity. One of the more significant oral complications is oral mucositis (OM) which induces severe pain and limits fundamental life behaviors such as eating, drinking, and talking. Although advancements in can...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02757-w
更新日期：2019-09-01 00:00:00
abstract：:Diabetes mellitus (DM) is associated with musculoskeletal damage. Investigations have indicated that healing of the surgically tenotomized Achilles tendon was considerably augmented following low-level laser therapy (LLLT) in non-diabetic, healthy animals. The aim of the present study was to evaluate the effect of LLL...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1074-7
更新日期：2013-02-01 00:00:00
abstract：:The purpose of this article was to analyze the photobiomodulator role of low-level laser therapy (LLLT) on the skeletal muscle remodeling following cryoinjury in rats, focusing the types I and III collagen proteins. Laser phototherapy has been employed to stimulate repair in different tissues. However, its role in ske...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0951-9
更新日期：2011-11-01 00:00:00
