Abstract：
:Reepithelialization and wound closure are the desired outcome for several ulcerative conditions. Such resolution reduces the possibility of wound contamination and maintenance of the injury and improves the reestablishment of tissue morphology and functions. Investigators are seeking adjuvant therapies that can accelerate wound healing and are developing new strategies for clinical applications. This study compared the effects of epidermal growth factor (EGF) application and low-level laser therapy (LLLT) on cultured epithelial cells. Cells were seeded in 24-well plates. After a 24-h incubation, the epithelial cells were either treated with EGF (100 μM in serum-free DMEM for 72 h) or subjected to LLLT (780 nm, 25 mW, 0.5, 1.5, and 3 J/cm2) by three applications every 24 h. Seventy-two hours after cells were treated with EGF or LLLT, cell migration, viability, proliferation, and collagen synthesis were assessed. Cells treated with EGF showed increased cell viability, proliferation, and collagen synthesis compared with those cells that received no treatment. LLLT enhanced cell migration; however, no significant effects of laser irradiation on other cell functions were observed. Comparison of both therapies demonstrated that EGF and LLLT enhanced specific epithelial cell activities related to wound healing.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Basso FG,Pansani TN,Cardoso LM,Citta M,Soares DG,Scheffel DS,Hebling J,de Souza Costa CAdoi
10.1007/s10103-017-2176-zsubject
Has Abstractpub_date
2018-02-01 00:00:00pages
445-449issue
2eissn
0268-8921issn
1435-604Xpii
10.1007/s10103-017-2176-zjournal_volume
33pub_type
杂志文章abstract：:Detection of demineralization of root surface caries is an important issue since preventive approaches prolong tooth life. Quantitative light-induced fluorescence (QLF) has been shown to be useful for the laboratory assessment of demineralization of root surfaces. The aim of this study was to determine the demineraliz...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0899-9
更新日期：2012-03-01 00:00:00
abstract：:Despite the positive effects of low-level laser therapy (LLLT) on muscle fatigue before exercises using a single muscle group, the acute effects of LLLT on performance in cardiopulmonary exercise testing (CPET) are poorly understood. We aimed to assess the acute effects of LLLT on physiologic and electromyographic res...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-014-1595-3
更新日期：2014-11-01 00:00:00
abstract：:The objective of this study was to describe the dynamics of water heating carried out by continuous laser radiation with wavelengths 1.47, 1.55, and 1.94 μm with different types of fibers used for endovenous laser coagulation. The study was conducted in water using high-speed surveying of the heating process through t...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03184-y
更新日期：2020-11-07 00:00:00
abstract：:Dermatosis papulosa nigra (DPN) is a common condition of pigmented skin. Whilst lesions are benign, they may be symptomatic or cosmetically disfiguring. Ablative lasers have previously been reported as a useful therapeutic modality in DPN. We report the largest case series to date of patients with DPN ablated with the...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-016-1906-y
更新日期：2016-04-01 00:00:00
abstract：:The effect of low-level laser therapy (LLLT) on the cardiovascular system is not fully established. Since the endothelium is an important endocrine element, establishing the mechanisms of LLLT action is an important issue.The aim of the study was to evaluate the effect of transdermal LLLT on endothelial function.In th...
journal_title：Lasers in medical science
pub_type： 临床试验,杂志文章
doi：10.1007/s10103-016-1971-2
更新日期：2016-09-01 00:00:00
abstract：:Photodynamic therapy (PDT) is used for the prevention and treatment of non-melanoma skin cancer. Until recently, clinically approved indications have been restricted to actinic keratoses, nodular and superficial basal cell carcinoma, and, since 2006, Bowen disease. However, the range of indications has been expanding ...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-009-0716-x
更新日期：2009-11-01 00:00:00
abstract：:A novel skin phantom is described that is constructed with quantifiable amounts of skin pigments, as well as a light scattering medium in the form of barium sulphate suspension. The two predominant skin pigments (melanin and haemoglobin) are varied in controlled amounts within the phantoms to simulate skin colour in d...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0495-1
更新日期：2008-10-01 00:00:00
abstract：:Low-energy laser irradiation (Ga-Al-As semiconductor laser, output 50 mW) was applied to rat osteoclast precursor cells for 1, 3, 6, or 10 min at 24-h intervals during the culture period. The number of tartrate-resistant acid phosphatase positive multinucleate cells was increased by approximately 1.3-fold in the 3- an...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-005-0368-4
更新日期：2006-04-01 00:00:00
abstract：:The aim of this study was to determine whether it is safe to use photo-activated disinfection (PAD) during root canal treatment without heating the periodontal tissues. Root canals of 30 freshly extracted single-rooted teeth were prepared using ProFiles up to size ISO 40 and then filled with photo-sensitiser: tolonium...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0526-y
更新日期：2009-01-01 00:00:00
abstract：:The aim of this work was to investigate the long-term effects of a single application of a water-cooled pulsed neodymium yttrium aluminium garnet (Nd:YAG) laser, in combination with scaling and root planing (SRP) for the treatment of periodontal inflammation. Twenty-two patients were included in this split-mouth singl...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-010-0807-8
更新日期：2011-11-01 00:00:00
abstract：:The most common cause of laryngitis is the laryngopharyngeal reflux disease. The symptoms of laryngitis can be hoarseness, globus, chronic cough, voice fatigue, throat pain, and dysphagia. Low-level laser therapy (LLLT) is beneficial to reduce the pain and inflammatory response without side effects. Therefore, LLLT ma...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1323-4
更新日期：2014-01-01 00:00:00
abstract：:The aim of this study was to evaluate the degree of conversion (DC) and to identify the viscoelastic properties: storage modulus (E'), loss modulus (E"), tangent delta (tan δ), and glass transition temperature (T g ) of a microhybrid resin-composite light-activated by three different protocols. A Filtek Z250 (3 M ESPE...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-014-1572-x
更新日期：2015-05-01 00:00:00
abstract：:The aim of this study is to evaluate the effectiveness of the low-level laser therapy (LLLT) in the control of pain, swelling, and trismus associated with surgical removal of impacted lower third molars. Thirty patients were randomized into two treatment groups, each with 15 patients-group test (LLLT) and a group cont...
journal_title：Lasers in medical science
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10103-012-1174-4
更新日期：2013-05-01 00:00:00
abstract：:We review the different spectroscopic techniques including the most recent laser-induced breakdown spectroscopy (LIBS) for the characterization of materials in any phase (solid, liquid or gas) including biological materials. A brief history of the laser and its application in bioscience is presented. The development o...
journal_title：Lasers in medical science
pub_type： 杂志文章,评审
doi：10.1007/s10103-011-0921-2
更新日期：2011-09-01 00:00:00
abstract：:This study aimed to evaluate in vitro performance of near-infrared laser transillumination (NIR-LTI) for detecting early occlusal caries in permanent teeth and compare it with quantitative light-induced fluorescence (QLF), DIAGNOdent Pen (DDPen), and conventional radiography (CR). Ninety-four occlusal surfaces present...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-014-1704-3
更新日期：2015-09-01 00:00:00
abstract：:Physical stimulation of body surface points is known to affect various organ functions. In traditional Chinese medicine, so-called acupoints were defined. These points can be physically stimulated to effectively treat various diseases. Here we describe for the first time the effect of CO(2) laser stimulation at the ac...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-011-0973-3
更新日期：2012-03-01 00:00:00
abstract：:The optical properties of hemoglobin could indicate the degree of hemolysis. We aimed to utilize this to develop a real-time blood damage monitoring device for cardiopulmonary bypass (CPB) systems. The real-time blood damage monitoring device comprised a near-infrared spectroscopy optical module with a fiber spectrome...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03094-z
更新日期：2020-07-10 00:00:00
abstract：:Primary hepatocellular carcinoma (HCC) and colon carcinoma are two of the most common clinical malignancies along with high morbidity and mortality. As low-power laser irradiation (LPLI) can induce cytotoxicity or cell apoptosis on several types of hyperplasia, LPLI may be a potential alternative treatment for gastroe...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02869-3
更新日期：2020-04-01 00:00:00
abstract：:Different ablation techniques have been utilized in the treatment of Barrett's esophagus (BE) to reduce the risk of degeneration. Treatment complications, risk of recurrence, and buried intestinal metaplasia (IM) are all major concerns. The effect of diode laser treatment on BE, studied in a group of patients over a l...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-010-0836-3
更新日期：2011-03-01 00:00:00
abstract：:The present study aimed to evaluate in vitro whether the low-level laser (LLL) delivering fractionated total energy (multiple irradiation) or single irradiation stimulates regeneration-associated events (viability and proliferation) in stem cells from human exfoliated deciduous teeth (SHED). Cells received LLL irradia...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-019-02836-y
更新日期：2019-12-01 00:00:00
abstract：:This study aimed to evaluate the effects of low-level laser therapy (LLLT) immediately before tetanic contractions in skeletal muscle fatigue development and possible tissue damage. Male Wistar rats were divided into two control groups and nine active LLLT groups receiving one of three different laser doses (1, 3, and...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-014-1560-1
更新日期：2014-09-01 00:00:00
abstract：:In periodontal therapy, the use of low-level diode lasers has recently been considered to improve wound healing of the gingival tissue. However, its effects on human gingival epithelial cells (HGECs) remain unknown. The aim of the present study was to examine whether high-frequency low-level diode laser irradiation st...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1292-7
更新日期：2014-07-01 00:00:00
abstract：:Low-level visible light irradiation was found to stimulate proliferation potential of various types of cells in vitro. Stem cells in general are of significance for implantation in regenerative medicine. The aim of the present study was to investigate the effect of low-level light irradiation on the proliferation of m...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-012-1207-z
更新日期：2013-07-01 00:00:00
abstract：:Quantitative characterization of skin collagen on photo-thermal response and its regeneration process is an important but difficult task. In this study, morphology and spectrum characteristics of collagen during photo-thermal response and its light-induced remodeling process were obtained by second-harmonic generation...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1296-3
更新日期：2014-01-01 00:00:00
abstract：PURPOSE:Acne scarring represents a common problem that negatively impacts patients' quality of life. Different types of treatments are currently available for this dermatological condition. This study evaluates the efficacy of a new 675-nm laser source system on acne scars with the use of established parameters that gu...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-020-03063-6
更新日期：2021-02-01 00:00:00
abstract：:Nitrogen laser-induced fluorescence (LIF) and tungsten halogen lamp excited diffuse reflectance spectra were recorded in 350- to 700-nm range on a miniature fiber-optic spectrometer from in vitro premolar tooth during various stages of artificial erosion with 36% phosphoric acid. Both the LIF spectral intensity and th...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-007-0489-z
更新日期：2008-07-01 00:00:00
abstract：:The aim of the present study was to investigate laser-fluorescence effects on the root surface. The possibility of detecting subgingival calculus should be evaluated to control complete calculus removal after scaling and root planing. Twenty freshly extracted human teeth, partially covered with calculus on the root su...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-002-0241-7
更新日期：2003-01-01 00:00:00
abstract：:The purpose of this study was to evaluate the thickness and qualitative characteristics of the hybrid layer after two cavity preparation methods, using Er:YAG laser in QSP mode and conventional carbide burs. Additionally, two different adhesive techniques were investigated using etch-and-rinse and self-etch adhesive s...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-018-2575-9
更新日期：2019-02-01 00:00:00
abstract：:The in vivo photodynamic activities of four poly(ethylene glycol) (PEG) conjugates of the photosensitiser 5,10,15,20-tetrakis-(m-hydroxyphenyl)chlorin (mTHPC, temoporfin, Foscan(®)) were compared with that of mTHPC over a range of drug-light intervals using acute tumour necrosis and skeletal muscles swelling in a mous...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s101030050019
更新日期：1999-03-01 00:00:00
abstract：:The aim of this study was to evaluate the shear bond strength (SBS) of a microhybrid composite resin bonded with three different adhesive systems to Er:YAG laser- (EL) or bur-prepared dentin surfaces and to analyze the quality and ultrastructure of the adhesive-dentin interfaces by scanning electron microscopy (SEM). ...
journal_title：Lasers in medical science
pub_type： 杂志文章
doi：10.1007/s10103-013-1424-0
更新日期：2015-02-01 00:00:00
