Abstract:
:The authors tested the diagnostic potential of the portable autofluorescence optical system that was developed in the preoperative evaluation of resection margins, and thus of the resection line safety in patients with low-positioned colorectal carcinoma. A total of 217 spectral measurements of the fluorescence properties of normal (117) and malignant (100) tissues in 19 patients with colorectal carcinoma were accomplished. The measured spectra thus acquired were then evaluated using logistic regression. Using the principal component method, the authors selected the 30 and 40 most significant wavelengths, respectively, which they then used to construct the logistic model. The model met the basic criteria of statistical significance. The classification power of the model was 79.7% (for 30 wavelengths) and 82.5% (for 40). Statistical discrimination was 0.88 and 0.91, respectively. These results confirm that the optical setup that we selected is suitable for the peroperative testing of the distal resection line. It is capable of differentiating with 90% confidence pathological tissue and thus of reliably guiding further histological processing.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Ducháč V,Zavadil J,Vránová J,Jirásek T,Stukavec J,Horák Ldoi
10.1007/s10103-010-0847-0subject
Has Abstractpub_date
2011-05-01 00:00:00pages
325-33issue
3eissn
0268-8921issn
1435-604Xjournal_volume
26pub_type
杂志文章abstract::Lasers have many favorable features as a light source owing to their monochromaticity and coherence. This study examined the mechanical properties of composite resins that were light-cured using a diode-pumped solid state (DPSS) laser. Eight composite resins were light-cured using four different light sources (one qua...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-012-1117-0
更新日期:2013-02-01 00:00:00
abstract::The purpose of this study was to evaluate the thickness and qualitative characteristics of the hybrid layer after two cavity preparation methods, using Er:YAG laser in QSP mode and conventional carbide burs. Additionally, two different adhesive techniques were investigated using etch-and-rinse and self-etch adhesive s...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-018-2575-9
更新日期:2019-02-01 00:00:00
abstract::This study aimed to investigate the influence of low-power gallium-aluminium-arsenide (GaAlAs) laser [830 nm, continuous wave (CW), 40 mW and fluence 4 J/cm(2)] on the healing of surgically created bone defects in rats treated with bioactive glass graft material. Surgical bone defects were created in the mandibles of ...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-008-0590-y
更新日期:2009-07-01 00:00:00
abstract::The erbium:YSGG and erbium:YAG lasers are used for tissue ablation in dermatology, dentistry and ophthalmology. The purpose of this study was to compare germanium oxide and sapphire optical fibres for transmission of sufficient Q-switched erbium laser pulse energies for potential use in both soft and hard tissue ablat...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-004-0316-8
更新日期:2004-01-01 00:00:00
abstract:INTRODUCTION:In-transit cutaneous malignant melanoma metastases remains a difficult and distressing disease. It is a sequela to the primary lesion represented by melanoma deposits between the site of excision and the draining lymph nodes. We present our experience of carbon dioxide ablation of in-transit cutaneous mali...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-008-0580-0
更新日期:2009-05-01 00:00:00
abstract::This retrospective case-control study aimed to compare 30 versus 40 W power of CO2 laser for the therapy of genitourinary syndrome of menopause (GSM). Postmenopausal women with severe intensity of dyspareunia and dryness were eligible to be included in this study. Primary outcomes were dyspareunia and dryness. Seconda...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2293-8
更新日期:2017-11-01 00:00:00
abstract::The objective of this study was to evaluate the safety and efficacy of flexible ureteroscopy (FURS) and holmium:YAG laser lithotripsy for the treatment of upper urinary tract stones in patients on active oral anticoagulants. The records of 1081 patients who underwent flexible ureteroscopic holmium:YAG (Ho:YAG) laser l...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2289-4
更新日期:2017-09-01 00:00:00
abstract::Low-level laser irradiation (LLLI) and recombinant human bone morphogenetic protein type 2 (rhBMP-2) have been used to stimulate bone formation. LLLI stimulates proliferation of osteoblast precursor cells and cell differentiation and rhBMP-2 recruits osteoprogenitor cells to the bone healing area. This in vivo study e...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-011-1022-y
更新日期:2012-09-01 00:00:00
abstract::There are many laser technologies that are being tested that claim to support hair regrowth for patients with alopecia areata (AA). In this paper, we will determine whether the body of evidence supports the use of devices using monochromatic light sources to treat AA. Articles were gathered from PubMed, Embase, and th...
journal_title:Lasers in medical science
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s10103-017-2412-6
更新日期:2018-02-01 00:00:00
abstract::This study aimed to compare the effects of photobiomodulation (PBM) in different energy densities and irradiances on maintaining cell viability, and proliferation of pulp fibroblasts from human primary teeth (HPF) were cultured in DMEM and used between the fourth and eighth passages. Then, HPF were irradiated with the...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2301-z
更新日期:2017-09-01 00:00:00
abstract::Low-back pain is very frequent, especially in active adult population. There are several different orthopaedic condition that can cause low-back pain, and the pain worsen the quality of life significantly. The treatments vary from drugs, physical therapies, kinesiology, local infiltrations, and so on. Laser therapy ha...
journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章
doi:10.1007/s10103-014-1684-3
更新日期:2015-01-01 00:00:00
abstract::The development of imaging technique to visualize and quantify the structural alteration of the spinal cord injury (SCI) may lead to better understanding and treatments of the injuries. In this work, multiphoton microscopy (MPM) based on two-photon excited fluorescence (TPEF) and second-harmonic generation (SHG) was t...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-018-2630-6
更新日期:2019-04-01 00:00:00
abstract::We describe the diversity of indications for laser hair removal (LHR) therapy and compare our experience with the literature. Patients' case notes referred to the Birmingham Regional Skin Laser Centre between 2003 and 2011 for laser hair removal, with indications other than hirsutism, were reviewed retrospectively. Th...
journal_title:Lasers in medical science
pub_type: 杂志文章,评审
doi:10.1007/s10103-013-1464-5
更新日期:2015-01-01 00:00:00
abstract::The purposes of the study were to evaluate the bond strength of bioceramic TotalFill root repair material (RRM) in retrograde cavities prepared using Er:YAG and Er,Cr:YSGG laser and steel bur, and to analyze failure modes. The root canals of 30 single-rooted teeth were endodontically treated, their root-ends were rese...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-019-02835-z
更新日期:2020-02-01 00:00:00
abstract::Reepithelialization and wound closure are the desired outcome for several ulcerative conditions. Such resolution reduces the possibility of wound contamination and maintenance of the injury and improves the reestablishment of tissue morphology and functions. Investigators are seeking adjuvant therapies that can accele...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2176-z
更新日期:2018-02-01 00:00:00
abstract::The aim of this study was to evaluate the efficacy of low-level laser therapy (LLLT) and alpha-lipoic acid (ALA) in the treatment of burning mouth syndrome (BMS) and secondary oral burning (SOB) by unstimulated sialometry, symptom assessment, and measurement of salivary TNF-α levels. Forty-four patients were randomize...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-018-2472-2
更新日期:2018-08-01 00:00:00
abstract::The purpose of this study is to determine the effectiveness of endoscopic diode laser therapy in patients presenting rectal bleeding due to chronic radiation proctitis (CRP). A retrospective analysis of CRP patients who underwent diode laser therapy in a single institution between 2010 and 2016 was carried out. The pa...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2323-6
更新日期:2018-01-01 00:00:00
abstract::We evaluated functional and morphological changes after trans-tympanic laser application using several different powers of photobiomodulation (PBM). The left (L) ears of 17 rats were irradiated for 30 min daily over 14 days using a power density of 909.1 (group A, 5040 J), 1136.4 (group B, 6300 J), and 1363.6 (group C...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-015-1851-1
更新日期:2016-02-01 00:00:00
abstract::Two-photon excited fluorescence (TPEF) microscopy, based on signal from cells, can provide detailed information on tissue architecture and cellular morphology in unstained histological sections to generate subcellular-resolution images from tissue directly. In this paper, we used TPEF microscopy to image microstructur...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-014-1652-y
更新日期:2015-01-01 00:00:00
abstract::The aim of this in vitro study was to evaluate some parameters of dental etching when irradiated with an erbium, chromium:yttrium-scandium-gallium-garnet (Er,Cr:YSGG) laser. One-hundred sound human third molars were selected and randomly distributed into ten groups (n = 10). The class V cavities of group 1 (control) w...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-008-0623-6
更新日期:2010-05-01 00:00:00
abstract::Lasers and light-emitting diodes are used for a range of biomedical applications with many studies reporting their beneficial effects. However, three main concerns exist regarding much of the low-level light therapy (LLLT) or photobiomodulation literature; (1) incomplete, inaccurate and unverified irradiation paramete...
journal_title:Lasers in medical science
pub_type: 杂志文章,评审
doi:10.1007/s10103-016-1914-y
更新日期:2016-05-01 00:00:00
abstract::High-intensity focused ultrasound (HIFU) can be applied noninvasively to create focused zones of tissue coagulation on various skin layers. We performed a comparative study of HIFU, evaluating patterns of focused tissue coagulation and ablation upon application thereof. A tissue-mimicking (TM) phantom was prepared wit...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-015-1804-8
更新日期:2015-12-01 00:00:00
abstract::Epithelial cells play an important role in reparative events. Therefore, therapies that can stimulate the proliferation and metabolism of these cells could accelerate the healing process. To evaluate the effects of low-level laser therapy (LLLT), human keratinocytes were irradiated with an InGaAsP diode laser prototyp...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-012-1057-8
更新日期:2013-02-01 00:00:00
abstract::Microvascular surgery is time consuming and requires high expertise. Laser-assisted vascular anastomosis (LAVA) is a promising sutureless technique that has the potential to facilitate this procedure. In this study, we evaluate the handling of our soldering material and the 1-week patency rate in a porcine model. Six ...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-017-2250-6
更新日期:2017-08-01 00:00:00
abstract::The traditional needle cricothyroidotomy procedure is performed blindly without any medical equipment. Complications including posterior tracheal wall perforation, accidental vessel puncture, and missed tracheal puncture are reported. Therefore, we proposed a dual-wavelength fiber-optic technique based on the techniqu...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-020-03065-4
更新日期:2020-07-23 00:00:00
abstract::Laser-assisted new attachment procedure (LANAP) is a new protocol that has been proposed for the treatment of periodontitis. However, there is little evidence regarding the rate of revascularization and the clinical efficacy of LANAP over conventional periodontal therapies. Hence, this study is done to evaluate and co...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-018-2451-7
更新日期:2018-08-01 00:00:00
abstract::This review aimed to identify the efficacy of low-level laser therapy (LLLT) in the management of orthodontic pain. This systematic review and meta-analysis was carried out in accordance with Cochrane Handbook and the PRISMA statement. An extensive literature search for RCTs, quasi-RCTs, and CCTs was performed through...
journal_title:Lasers in medical science
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s10103-012-1196-y
更新日期:2013-11-01 00:00:00
abstract::Burn scars are known for their tendency to worsen with hypertrophy and contracture, causing esthetic and functional problems. The objective is to analyze the effectiveness of low-level laser therapy on post-burn hypertrophic scar tissue in children. A randomized controlled study included 15 children, ranging from 2 to...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-018-2572-z
更新日期:2018-12-01 00:00:00
abstract::Laser excision has been used with increasing success to treat oral leukoplakia. The aim of the present study was to evaluate whether clinical healing of a leukoplakia after laser surgery is associated with a normal functional status of the new epithelium and whether pathological alterations in these parameters are rel...
journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章
doi:10.1007/s10103-011-0941-y
更新日期:2012-01-01 00:00:00
abstract::Unlike other rosacea therapies which need daily takings or applications over long periods, the edge of lasers and light-based therapies (LLBT) is the limited number of sessions to achieve improvement. The proper selection of the adequate physical device in accordance with the patients' skin features and rosacea-relate...
journal_title:Lasers in medical science
pub_type: 杂志文章,评审
doi:10.1007/s10103-020-03200-1
更新日期:2021-01-03 00:00:00