Abstract:
:The aim of this study was to evaluate the efficacy of low-level laser therapy (LLLT) and alpha-lipoic acid (ALA) in the treatment of burning mouth syndrome (BMS) and secondary oral burning (SOB) by unstimulated sialometry, symptom assessment, and measurement of salivary TNF-α levels. Forty-four patients were randomized into four treatment groups: BMS/laser (n = 10), BMS/ALA (n = 5), SOB/laser (n = 15), and SOB/ALA (n = 14). The control group consisted of eight healthy female subjects. Unstimulated salivary flow was measured before and after treatment, and the collected saliva was stored at - 20 °C for the analysis of TNF-α. Symptoms were evaluated before and after treatment using a pain visual analog scale. Most patients were women (81.8%) during menopause (72.2%). LLLT and ALA were efficient in increasing salivary flow only in BMS but provided symptom relief in both conditions. TNF-α levels did not differ between patients with BMS and SOB or between those patients and the control group. No differences were observed in posttreatment TNF-α levels in either condition. The results of this study suggest that LLLT and ALA are efficient therapies in reducing burning mouth symptoms, with LLLT being more efficient than ALA.
journal_name
Lasers Med Scijournal_title
Lasers in medical scienceauthors
Barbosa NG,Gonzaga AKG,de Sena Fernandes LL,da Fonseca AG,Queiroz SIML,Lemos TMAM,da Silveira ÉJD,de Medeiros AMCdoi
10.1007/s10103-018-2472-2subject
Has Abstractpub_date
2018-08-01 00:00:00pages
1255-1262issue
6eissn
0268-8921issn
1435-604Xpii
10.1007/s10103-018-2472-2journal_volume
33pub_type
杂志文章,随机对照试验abstract::The most common cause of laryngitis is the laryngopharyngeal reflux disease. The symptoms of laryngitis can be hoarseness, globus, chronic cough, voice fatigue, throat pain, and dysphagia. Low-level laser therapy (LLLT) is beneficial to reduce the pain and inflammatory response without side effects. Therefore, LLLT ma...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-013-1323-4
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abstract::Two-photon excited fluorescence (TPEF) microscopy, based on signal from cells, can provide detailed information on tissue architecture and cellular morphology in unstained histological sections to generate subcellular-resolution images from tissue directly. In this paper, we used TPEF microscopy to image microstructur...
journal_title:Lasers in medical science
pub_type: 杂志文章
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abstract::Oral lichen planus (OLP) is an inflammatory disease that can be painful, mainly in the atrophic and erosive forms. Numerous drugs have been used with dissimilar results, but most treatments are empirical. However, to date, the most commonly employed and useful agents for the treatment of OLP are topical corticosteroid...
journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-013-1424-0
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abstract::Osteoarthritis (OA) triggers increased levels of inflammatory markers, including prostaglandin (PG) E2 and proinflammatory cytokines. The elevation of cytokine levels is closely associated with increased articular tissue degeneration. Thus, the use of combination therapies may presumably be able to enhance the effects...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-016-2091-8
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abstract::The aim of the present study was to investigate and compare the effects of high intensity laser therapy (HILT) and low level laser therapy (LLLT) on the treatment of patients with Bell's palsy. Forty-eight patients participated in and completed this study. The mean age was 43 ± 9.8 years. They were randomly assigned i...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10103-013-1352-z
更新日期:2014-01-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-016-1956-1
更新日期:2016-08-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章
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journal_title:Lasers in medical science
pub_type: 杂志文章
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更新日期:2018-08-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-010-0830-9
更新日期:2012-01-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-011-0953-7
更新日期:2012-03-01 00:00:00
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-010-0775-z
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journal_title:Lasers in medical science
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journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-019-02899-x
更新日期:2020-08-01 00:00:00
abstract::We observed the promoting effects of the 2940-nm erbium:YAG (Er:YAG) fractional laser in topical drug delivery for psoriasis. A total of five (four males and one female) recalcitrant psoriasis patients were given laser treatment eight times at 1-week intervals with the following parameters: 5-11% spot density and 100-...
journal_title:Lasers in medical science
pub_type: 临床试验,杂志文章
doi:10.1007/s10103-017-2259-x
更新日期:2017-08-01 00:00:00
abstract::This study aimed to investigate the influence of low-power gallium-aluminium-arsenide (GaAlAs) laser [830 nm, continuous wave (CW), 40 mW and fluence 4 J/cm(2)] on the healing of surgically created bone defects in rats treated with bioactive glass graft material. Surgical bone defects were created in the mandibles of ...
journal_title:Lasers in medical science
pub_type: 杂志文章
doi:10.1007/s10103-008-0590-y
更新日期:2009-07-01 00:00:00
abstract::To evaluate the efficacy and safety of holmium laser enucleation of prostate (HoLEP) for treating urinary retention in patients with advanced prostate cancer. Thirty-eight cases of advanced prostate cancer with urinary retention were enrolled in this retrospective study. All the 38 patients were treated with CAB as a ...
journal_title:Lasers in medical science
pub_type: 杂志文章
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journal_title:Lasers in medical science
pub_type: 杂志文章
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journal_title:Lasers in medical science
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pub_type: 杂志文章
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journal_title:Lasers in medical science
pub_type: 杂志文章
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更新日期:2018-02-01 00:00:00
abstract::Transoral laser microsurgery (TLM) is an emerging technique for the management of laryngeal and other head and neck malignancies. It is increasingly being used in place of traditional open surgery because of lower morbidity and improved organ preservation. Since the surgery is performed from the inside working outward...
journal_title:Lasers in medical science
pub_type: 杂志文章,评审
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更新日期:2011-01-01 00:00:00
abstract::Core-shell nanoparticles have unusual physical, chemical and biological properties. Until now, for the Ag and TiO2 combination, only Ag core and TiO2 shell nanoparticles have been practically demonstrated. In this investigation, novel TiO2@Ag core-shell (TiO2 core and Ag shell) nanoparticles were produced via ultrason...
journal_title:Lasers in medical science
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abstract::In this study, shear bond strength (SBS) of metal orthodontic brackets to porcelain following conditioning by Er:YAG (erbium-doped yttrium aluminum garnet) and Nd:YAG (neodymium-doped yttrium aluminum garnet) laser in comparison to conventional methods was evaluated. One hundred glazed porcelain discs with an upper ce...
journal_title:Lasers in medical science
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abstract::We describe the diversity of indications for laser hair removal (LHR) therapy and compare our experience with the literature. Patients' case notes referred to the Birmingham Regional Skin Laser Centre between 2003 and 2011 for laser hair removal, with indications other than hirsutism, were reviewed retrospectively. Th...
journal_title:Lasers in medical science
pub_type: 杂志文章,评审
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journal_title:Lasers in medical science
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journal_title:Lasers in medical science
pub_type: 杂志文章
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abstract::Recent studies have investigated whether low level laser therapy (LLLT) can optimize human muscle performance in physical exercise. This study tested the effect of LLLT on muscle performance in physical strength training in humans compared with strength training only. The study involved 36 men (20.8±2.2 years old), cl...
journal_title:Lasers in medical science
pub_type: 杂志文章,随机对照试验
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更新日期:2011-05-01 00:00:00
abstract::Lasers and light-emitting diodes are used for a range of biomedical applications with many studies reporting their beneficial effects. However, three main concerns exist regarding much of the low-level light therapy (LLLT) or photobiomodulation literature; (1) incomplete, inaccurate and unverified irradiation paramete...
journal_title:Lasers in medical science
pub_type: 杂志文章,评审
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